0. DOCID:22388 SCORE: 0.00352122227147568
DOCNO: 7554509
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Health Behavior
QUALIFIER: prevention & control
AUTHOR: J S Rossi JS
AUTHOR: L M Blais LM
AUTHOR: C A Redding CA
AUTHOR: M A Weinstock MA
AFFILIATION: Department of Psychology, University of Rhode Island, Kingston, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Dermatologic clinics.
COUNTRY: UNITED STATES
TITLE: Preventing skin cancer through behavior change. Implications for interventions.
PUBDATE: 19950701
Sun exposure is the only major causative factor for skin cancer for which prevention is feasible. Both individual and community-based interventions have been effective in changing sun exposure knowledge and attitudes but generally have not been effective in changing behaviors. An integrative model of behavior change is described that has been successful in changing behavior across a wide range of health conditions. This model holds promise for developing a rational public health approach to skin cancer prevention based on sound behavioral science.

1. DOCID:22416 SCORE: 0.00352122092672893
DOCNO: 8091052
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
QUALIFIER: therapy
AUTHOR: L Perey L
AUTHOR: S Leyvraz S
AFFILIATION: Centre pluridisciplinaire d'oncologie, Lausanne.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Schweizerische Rundschau für Medizin Praxis = Revue suisse de médecine Praxis.
COUNTRY: SWITZERLAND
TITLE: [Primary and adjuvant treatment of breast cancer: an update]
PUBDATE: 19940801
Several articles covering treatment of mammary carcinoma in situ and invading mammary cancer have been published recently. This article delivers a short description of the clinical picture and the treatment of a noninvasive tumor as well as of the mainly conservative primary treatment of invasive carcinoma in common use since 20 years. Systemic adjuvant treatment is discussed in the context of results from a meta-analysis publishes two years ago in 'Lancet'. Finally, various directives for the execution of an adjuvant treatment are given that are offered today outside of a study protocol.

2. DOCID:21432 SCORE: 0.00317445279439055
DOCNO: 9167659
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: prevention & control
AUTHOR: R M Freid RM
AUTHOR: N S Davis NS
AUTHOR: G H Weiss GH
AFFILIATION: Department of Urology, University of Cincinnati College of Medicine, Ohio, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The Medical clinics of North America.
COUNTRY: UNITED STATES
TITLE: Prostate cancer screening and management.
PUBDATE: 19970501
Several other newer therapeutic modalities are being investigated to determine their potential role in the treatment of prostate cancer. Cryotherapy, microwave hyperthermia, laser therapy, and high-intensity focused ultrasound have all been introduced in recent years. Each of these techniques is based on a different principle, yet they all attempt to kill prostate cancer cells in a minimally invasive manner. Insufficient follow-up data are available to allow strong recommendations regarding these treatments.

3. DOCID:22108 SCORE: 0.00290787471785965
DOCNO: 9256902
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Neoplasm Regression, Spontaneous
QUALIFIER: secondary
QUALIFIER: pathology
QUALIFIER: secondary
QUALIFIER: secondary
AUTHOR: J Lokich J
AFFILIATION: Cancer Center of Boston at Plymouth, Framingham, MA, USA.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: American journal of clinical oncology : the official publication of the American Radium Society.
COUNTRY: UNITED STATES
TITLE: Spontaneous regression of metastatic renal cancer. Case report and literature review.
PUBDATE: 19970801
A case of spontaneous regression of pleural and intrapulmonary metastases from renal cell cancer is reported with more than 60 cases reported since the original review of this clinical phenomenon in 1964. The metastatic disease sites are most often pulmonary, but extrapulmonary sites include liver, bone, and CNS regressions. The role of nephrectomy in "spontaneous regression" continues to be obscure, accounting for < 50% of documented cases. Immunologic mechanisms, although intellectually attractive, have not been identified.

4. DOCID:22997 SCORE: 0.00282263979371401
DOCNO: 7554603
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Laparoscopy
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: W H Parker WH
AFFILIATION: University of California at Los Angeles, School of Medicine, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Clinical obstetrics and gynecology.
COUNTRY: UNITED STATES
TITLE: The case for laparoscopic management of the adnexal mass.
PUBDATE: 19950601
Careful patient selection criteria can be used to identify patients who are appropriate for management of an adnexal masses via operative laparoscopy. Proper intraoperative assessment and liberal use of rapid frozen section are also important for optimal clinical outcome. Reported studies show that laparoscopic management of adnexal masses can be safely done. The short hospital stay and rapid return to normal activity combine to potentially reduce the overall cost of patient care. When cancer is unexpectedly found at the time of laparoscopic surgery for an adnexal mass, the surgeon should be prepared to proceed with staging laparotomy for appropriate treatment.

5. DOCID:23317 SCORE: 0.00269527968668065
DOCNO: 9127168
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: physiology
QUALIFIER: physiology
QUALIFIER: enzymology
QUALIFIER: physiology
AUTHOR: S R Bramhall SR
AFFILIATION: University Department of Surgery, Queen Elizabeth Hospital, Birmingham, UK.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: International journal of pancreatology : official journal of the International Association of Pancreatology.
COUNTRY: UNITED STATES
TITLE: The matrix metalloproteinases and their inhibitors in pancreatic cancer. From molecular science to a clinical application.
PUBDATE: 19970201
The matrix metalloproteinases (MMPs) and their tissue-specific inhibitors (TIMPs) are described and their roles in tumor invasion and metastasis are reviewed. The expression and activity of the MMPs and TIMPs in pancreatic cancer is reported and illustrated with immunohistochemistry and in situ hybridization. The role of MMP inhibitors (MMPIs) is reviewed in vivo and the use of novel MMPIs, e.g., BB94 (Batimastat) and BB2516 (Marimastat); in animal experiments are also described. Finally, the preliminary results from a phase 2 trial of BB2516 (Marimastat) in pancreatic cancer are reported.

6. DOCID:21121 SCORE: 0.00266679475140526
DOCNO: 9073307
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: chemistry
QUALIFIER: pharmacology
QUALIFIER: pharmacology
AUTHOR: H Knudsen H
AUTHOR: P E Nielsen PE
AFFILIATION: Department of Medical Biochemistry & Genetics, The Panum Institute, Copenhagen N, Denmark.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Anti-cancer drugs.
COUNTRY: ENGLAND
TITLE: Application of peptide nucleic acid in cancer therapy.
PUBDATE: 19970201
Peptide nucleic acid (PNA) is a DNA mimic with a pseudopeptide backbone composed of aminoethyl glycine units. Several features of PNA, such as superior hybridization affinities to RNA and DNA, high biological stability, and convenient solid-phase synthesis, make it a promising candidate for use as a gene targeting drug. Here we review the chemical and biological properties of PNA in relation to its potential as an anti-cancer drug.

7. DOCID:23148 SCORE: 0.00259436012660876
DOCNO: 8800010
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: methods
QUALIFIER: secondary
QUALIFIER: surgery
AUTHOR: K M McMasters KM
AUTHOR: M J Edwards MJ
AFFILIATION: Department of Surgery, University of Louisville School of Medicine, KY 40292, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The Journal of the Kentucky Medical Association.
COUNTRY: UNITED STATES
TITLE: Liver cryosurgery.
PUBDATE: 19960601
Liver cryosurgery is a relatively new form of treatment for unresectable liver cancer that involves in situ ablation of liver tumors by freezing them with liquid nitrogen. Cryosurgery has been used mainly to treat liver metastases from colorectal cancer, but other types of metastases and primary liver cancers have been treated as well. Results of liver cryosurgery over the past decade have demonstrated that it is a safe and effective treatment for malignant liver tumors. Because only a small percentage of primary and metastatic liver tumors are resectable, cryosurgery offers a potentially curative treatment option for patients with unresectable disease.

8. DOCID:23186 SCORE: 0.00251032019851168
DOCNO: 7856476
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: secondary
QUALIFIER: secondary
AUTHOR: G Iaconetta G
AUTHOR: E Lamaida E
AUTHOR: A Rossi A
AUTHOR: F Signorelli F
AUTHOR: A Manto A
AUTHOR: A Giamundo A
AFFILIATION: Institute of Neurosurgery, Medical Oncology, School of Medicine, University Federico II of Naples.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Acta neurologica.
COUNTRY: ITALY
TITLE: Leptomeningeal carcinomatosis: review of the literature.
PUBDATE: 19940801
Metastases from solid tumors that seed the leptomeninges (meningeal carcinomatosis) are an important neurologic complication of systemic cancer. Recently many authors have reported that its incidence is increasing; particularly it has been demonstrated for breast cancer and small cell bronchogenic carcinoma. A cytologic examination of cerebrospinal fluid (CSF) establishes the diagnosis. Gadolinium-enhanced MRI has demonstrated superiority over other imaging with the clinical context and CSF analysis may lead to a rapid diagnosis and treatment of leptomeningeal carcinomatosis. Despite all measures, prognosis remains poor because of the presence of multiple metastases elsewhere.

9. DOCID:20552 SCORE: 0.00249626172180554
DOCNO: 7766364
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
AUTHOR: S A Lamb SA
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Critical care nursing clinics of North America.
COUNTRY: UNITED STATES
TITLE: Radiation therapy options for management of the brain tumor patient.
PUBDATE: 19950301
Radiation therapy rarely cures malignant brain tumors; however, it is the best treatment available at present. Refinement of radiation delivery systems must continue in order to minimize normal tissue injury and to maximize the quality of life. Multimodal therapy designed to attack cancer at its genetic makeup holds great promise. Radiation therapy will always remain one of the forms of therapy used to treat malignant brain tumors.

10. DOCID:23813 SCORE: 0.0024923211317001
DOCNO: 9184378
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Cancer Vaccines
QUALIFIER: genetics
QUALIFIER: methods
QUALIFIER: methods
QUALIFIER: immunology
QUALIFIER: therapy
AUTHOR: E M Jaffee EM
AUTHOR: D M Pardoll DM
AFFILIATION: The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Methods (San Diego, Calif.)
COUNTRY: UNITED STATES
TITLE: Considerations for the clinical development of cytokine gene-transduced tumor cell vaccines.
PUBDATE: 19970601
In preclinical models, tumor cells genetically altered to secrete cytokines or express costimulatory molecules can generate systemic antitumor immunity. In some studies, these tumor vaccines have been shown to eradicate micrometastases. These results have led to the initiation of numerous phase I clinical trials employing either genetically modified or allogenic tumor vaccines. This article addresses a number of issues related to the clinical development of cytokine gene-transduced tumor cell vaccines including: (1) the production of cytokine-secreting tumor vaccines; and (2) the preclinical feasibility and toxicity studies required for testing these vaccines in patients with cancer.

11. DOCID:21339 SCORE: 0.00246930388504694
DOCNO: 7721161
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Body Mass Index
QUALIFIER: chemistry
QUALIFIER: analysis
AUTHOR: J Kotarski J
AFFILIATION: II Kliniki Ginekologii Operacyjnej Akademii Medycznej w Lublinie.
PUBTYPE: Journal Article
JOURNALTITLE: Ginekologia polska.
COUNTRY: POLAND
TITLE: [Estrone concentration in endometrial cancer tissue in relation to body mass]
PUBDATE: 19940901
The estrone concentration was estimated in tissue of endometrial cancer and in the serum of 103 postmenopausal women. Patients were divided into two subgroups: normal body mass and overweight (above 130% of ideal body mass). The mean (+/- SED) tissue estrone concentration in women with normal body mass was 0.54 +/- 0.06 pmol/g tissue and did not differ from that of overweight. Tissue estrone concentration correlated positively with Broc Index in subgroup with normal body mass and not in overweight.

12. DOCID:22236 SCORE: 0.00239304945755431
DOCNO: 7974900
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: J E Montie JE
AFFILIATION: Department of Urology, Wayne State University School of Medicine, Detroit, Michigan.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The Urologic clinics of North America.
COUNTRY: UNITED STATES
TITLE: Follow-up after penectomy for penile cancer.
PUBDATE: 19941101
The primary area of concern for follow-up after initial therapy for penile cancer is the inguinal lymph nodes. Physical examination is the mainstay for follow-up but inguinal computed tomography scans can be of benefit in selected patients. Follow-up must be weighed heavily in the first 6 to 12 months as most metastases are noted in this period. Close follow-up is justifiable in penile cancer because many patients may be cured in spite of low volume inguinal lymph node metastatic disease. A proposed follow-up strategy is presented.

13. DOCID:21007 SCORE: 0.00235418517013704
DOCNO: 7827419
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: administration & dosage
QUALIFIER: drug therapy
AUTHOR: J M Murray JM
AFFILIATION: School of Mathematics, University of New South Wales, Kensington, Australia.
PUBTYPE: Journal Article
JOURNALTITLE: Mathematical biosciences.
COUNTRY: UNITED STATES
TITLE: Optimal drug regimens in cancer chemotherapy for single drugs that block progression through the cell cycle.
PUBDATE: 19941001
In this paper we study the application of a single drug in cancer chemotherapy where the drug can block progression through the cell cycle. Under certain conditions we determine the regimen that reduces the tumor population to a desired endpoint in minimal time while keeping a normal cell population above some lower limit. We also study the sensitivity of the optimal solution to various parameters.

14. DOCID:22561 SCORE: 0.0023475028522886
DOCNO: 8748088
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Models, Biological
QUALIFIER: therapeutic use
QUALIFIER: prevention & control
AUTHOR: Y Hirata Y
AFFILIATION: Hirata Hospital, Kochi City, Japan.
PUBTYPE: Journal Article
JOURNALTITLE: Medical hypotheses.
COUNTRY: ENGLAND
TITLE: An enzymatic effect for cancer prevention and eradication.
PUBDATE: 19951101
As previously described in a series of hypotheses, cancer development depends on an unconvertable duplication mitosis caused by some abnormal supplement of the mitotic maturation promoting system which is paralyzed in the cancerous cell's cytoplasm. This abnormal supplement, which may be responsible for the cancer's development, must be a biochemical compound that could be eliminated by exposure to the action of certain enzymes. Accordingly, in order to prevent and eradicate cancer development in general, an enzyme which would destroy and eliminate the biochemical supplement needs to be identified, and a specific method of delivering the enzyme to the supplement needs to be devised.