0. DOCID:27723 SCORE: 0.00308969172930824
DOCNO: 15616627
OWNER: NLM
STATUS: PubMed-not-MEDLINE
AUTHOR: A Cases A
AFFILIATION: Department of Nephrology, Hospital Clínic, Barcelona, Spain.
PUBTYPE: Journal Article
JOURNALTITLE: Drug news & perspectives.
COUNTRY: Spain
TITLE: Recent advances in hypertension research and management.
PUBDATE: 19980801
At the 17th Scientific Meeting of the International Society of Hypertension (Amsterdam, June 7-11, 1998), clinicians and scientists from all over the world exchanged the results of latest research on the pathophysiology, prevention and management of hypertension. Progress in two key areas of basic research was presented at the meeting: ion channels and experimental genetics. In the clinical arena, a number of large, long-term studies were presented on topics that included risk factors of cardiovascular events in male hypertensives; antihypertensive therapy and the risk of cancer; and antihypertensive therapy in dementia. A population-wide approach was stressed as essential in a session on diet intervention and hypertension in the 21st century.

1. DOCID:27295 SCORE: 0.00307780529699003
DOCNO: 10363960
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: prevention & control
QUALIFIER: utilization
QUALIFIER: statistics & numerical data
QUALIFIER: statistics & numerical data
PUBTYPE: Journal Article
JOURNALTITLE: MMWR. Morbidity and mortality weekly report.
COUNTRY: UNITED STATES
TITLE: Patients' reports of counseling on mammography screening by health-care providers--North Carolina, 1997.
PUBDATE: 19990501
Regular mammography screening combined with timely and appropriate treatment can reduce mortality from breast cancer by 30% in women aged 50-69 years and 16% in women aged 40-49 years. A physician's recommendation has been strongly associated with a patient having a mammogram. This report analyzes data collected during 1997 in North Carolina as part of the Behavioral Risk Factor Surveillance System (BRFSS), which indicated that 23% of women aged > or =40 years who had had a routine physical examination during the 2 years preceding the survey did not recall having a discussion about mammography with a health-care provider.

2. DOCID:27506 SCORE: 0.00287762378877288
DOCNO: 9735127
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Lymph Node Excision
DESCRIPTOR: Lymphatic Metastasis
DESCRIPTOR: Thyroidectomy
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: H Chen H
AUTHOR: R Udelsman R
AFFILIATION: Division of Surgical Oncology, Johns Hopkins Hospital, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Surgical oncology clinics of North America.
COUNTRY: UNITED STATES
TITLE: Papillary thyroid carcinoma: justification for total thyroidectomy and management of lymph node metastases.
PUBDATE: 19981001
Papillary thyroid carcinoma (PTC) is the most common epithelial thyroid tumor and comprises approximately 80% of all thyroid cancers. In this article, the authors discuss the data showing that total thyroidectomy is the treatment of choice of clinically significant PTC, and review an algorithm for the management of lymph node metastases. Although the prognosis for patients with PTC is generally good, appropriate surgical management (total thyroidectomy plus 131I and life-long TSH suppression) can further reduce recurrence and cancer death rates significantly.

3. DOCID:26144 SCORE: 0.00270857578452313
DOCNO: 10869101
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
AUTHOR: D W Lamson DW
AUTHOR: M S Brignall MS
AFFILIATION: Bastyr University - Kenmore, WA, USA. davisl@seanet.com
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Alternative medicine review : a journal of clinical therapeutic.
COUNTRY: UNITED STATES
TITLE: Antioxidants and cancer, part 3: quercetin.
PUBDATE: 20000601
Quercetin is a flavonoid molecule ubiquitous in nature. A number of its actions make it a potential anti-cancer agent, including cell cycle regulation, interaction with type II estrogen binding sites, and tyrosine kinase inhibition. Quercetin appears to be associated with little toxicity when administered orally or intravenously. Much in vitro and some preliminary animal and human data indicate quercetin inhibits tumor growth. More research is needed to elucidate the absorption of oral doses and the magnitude of the anti-cancer effect.

4. DOCID:27589 SCORE: 0.00255531119228448
DOCNO: 10391016
AUTHOR: D A Cooper DA
AUTHOR: A L Eldridge AL
AUTHOR: J C Peters JC
AFFILIATION: Department of Regulatory and Clinical Development, Food and Beverage Products, Procter & Gamble Company, Cincinnati, OH 45224-1703, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Nutrition reviews.
COUNTRY: UNITED STATES
TITLE: Dietary carotenoids and lung cancer: a review of recent research.
PUBDATE: 19990501
Several hundred carotenoid research studies have been published since 1996, when two major intervention trials showed a lack of protective effect of beta-carotene supplements against lung cancer. Recent epidemiologic studies continue to show an association between high dietary intake of beta-carotene and lower risk of lung cancer. New research is attempting to clarify the apparently contradictory results of intervention and epidemiologic studies. Promising areas of investigation include characterizing biologic activities of carotenoids and gaining further insight into whether they may serve primarily as markers for a healthy lifestyle or diet.

5. DOCID:26603 SCORE: 0.00251632386031549
DOCNO: 10206304
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Genes, myc
DESCRIPTOR: Polymorphism, Restriction Fragment Length
QUALIFIER: genetics
AUTHOR: M J Ejarque MJ
AUTHOR: M Vicente M
AUTHOR: M Bernués M
AUTHOR: A Oliver A
AUTHOR: J Vicente J
AUTHOR: G Capellá G
AUTHOR: F Lluís F
AUTHOR: G Chéchile G
AFFILIATION: Urology Service, Fundació Puigvert, Barcelona, Spain.
PUBTYPE: Journal Article
JOURNALTITLE: British journal of cancer.
COUNTRY: SCOTLAND
TITLE: Restriction fragment length polymorphism of the L-myc gene is not a prognostic factor in bladder cancer patients.
PUBDATE: 19990401
The L-myc restriction fragment length polymorphism has been suggested to be of prognostic significance in some types of primary tumours. We examined the prognostic and susceptibility significance of the L-myc genotype in a group of 98 bladder cancer patients. The L-myc genotype did not correlate with any pathologic parameter and does not offer any clinical utility in patients with bladder cancer.

6. DOCID:27376 SCORE: 0.00239344666940715
DOCNO: 10494319
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: blood
QUALIFIER: diagnosis
QUALIFIER: immunology
QUALIFIER: blood
AUTHOR: L F Wymenga LF
AUTHOR: H J Mensink HJ
AFFILIATION: Martini Ziekenhuis, afd. Urologie, Groningen.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Nederlands tijdschrift voor geneeskunde.
COUNTRY: NETHERLANDS
TITLE: [Prostate-specific antigen as a tumor marker of prostate carcinoma]
PUBDATE: 19990801
Prostate specific antigen (PSA) is currently the tumour marker of choice for prostatic carcinoma. Various indices of PSA have been developed in an attempt to refine its sensitivity and improve its clinical value. These include the ratio of serum PSA level and prostate volume, the rate of change of the PSA level with time, age-referenced PSA, and the proportion of free PSA in serum relative to total PSA (free to total PSA ratio). The free to total PSA ratio is lower in patients with prostate cancer than in those with elevated PSA levels due to benign prostatic hyperplasia.

7. DOCID:27412 SCORE: 0.00239344550614514
DOCNO: 14538145
OWNER: NLM
STATUS: PubMed-not-MEDLINE
AUTHOR: S Scheinbach S
AFFILIATION: Nabisco Research, Schaeberle Technology Center, 200 DeForest Ave., E. Hanover, New Jersey 07936, USA. ScheinbachS@Nabisco.com
PUBTYPE: Journal Article
JOURNALTITLE: Biotechnology advances.
COUNTRY: England
TITLE: Probiotics: functionality and commercial status.
PUBDATE: 19980501
Probiotics in the form of fermented milk products have been consumed for centuries. In this century various health benefits have been purported to result from consumption of foods containing live microorganisms, particularly lactic acid bacteria (LAB). Probiotics can provide relief for lactose intolerant individuals and reduce bouts of diarrhea. Evidence for other claims such as lowering serum cholesterol, suppressing cancer and stimulating the immune system remains to be clearly established by conducting well-controlled, statistically-valid clinical trials. Although the benefits to healthy individuals are uncertain, many consumers especially in Japan and Europe, perceive probiotic products to be healthful, and sales are robust.

8. DOCID:27940 SCORE: 0.00235357175912633
DOCNO: 10211509
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: J Cebrian J
AUTHOR: S W Larach SW
AUTHOR: A Ferrara A
AUTHOR: P R Williamson PR
AUTHOR: M F Trevisani MF
AUTHOR: H J Lujan HJ
AUTHOR: A Kassir A
AFFILIATION: Colon and Rectal Clinic of Orlando, Florida 32806, USA.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Diseases of the colon and rectum.
COUNTRY: UNITED STATES
TITLE: Small-cell carcinoma of the rectum: report of two cases.
PUBDATE: 19990201
Small-cell carcinoma of the rectum is an infrequent pathologic finding, and its precise incidence is unknown. Its incidence is less than 0.2 percent among all colorectal cancers. This tumor manifests highly aggressive behavior. The treatment of choice is combination chemotherapy similar to that used for small-cell carcinoma of the lung, but in small localized tumors surgery plus chemotherapy is an alternative. We present two cases of small-cell carcinoma of the lower rectum and a review of the literature.

9. DOCID:27950 SCORE: 0.00226542171010741
DOCNO: 9793012
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: secondary
QUALIFIER: therapy
AUTHOR: P Puri P
AUTHOR: S K Datta SK
AFFILIATION: Department of Ophthalmology, Hull Royal Infirmary, UK.
PUBTYPE: Journal Article
JOURNALTITLE: European journal of cancer care.
COUNTRY: ENGLAND
TITLE: Management of choroidal metastasis: a report.
PUBDATE: 19980901
Cancers metastatic to the eye are the most common intraocular malignancy, the choroid being the most common site of affection. Breast and lung cancers are the two most common malignancies metastatic to the eye. Patients usually present with diminished visual acuity of field loss. Management of these cases is very gratifying with a large majority of patients showing resolution and maintenance of useful vision in the involved eye. This communication presents our experience in management of a case of choroidal metastasis from a breast primary. A combination of radiotherapy and chemotherapy lead to complete resolution of the lesion with no recurrences in a follow-up of over 6 months.

10. DOCID:27605 SCORE: 0.00218967085415648
DOCNO: 9864888
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Taxoids
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: drug therapy
QUALIFIER: analogs & derivatives
QUALIFIER: therapeutic use
AUTHOR: M Espié M
AUTHOR: C Cuvier C
AUTHOR: A Gorins A
AUTHOR: M Marty M
AFFILIATION: Centre des Maladies du Sein, Oncologie Médicale, Hôpital Saint-Louis, Paris.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Contraception, fertilité, sexualité (1992)
COUNTRY: FRANCE
TITLE: [Taxanes in the treatment of breast and ovarian cancers: current indications and results]
PUBDATE: 19981101
Since the last years, taxanes are among the most active molecules in the treatment of advanced breast and ovarian cancers. Concerning the ovarian cancer, Paclitaxel in association with Cisplatinum is about to become the first line reference protocol. Studies are going on in order to define the association and the optimal way of administration. Concerning breast cancer, Docetaxel seems to provide the most interesting response rates after failures of anthracyclines. In France, randomised studies in adjuvant situation have started with this molecule.

11. DOCID:27277 SCORE: 0.0021717180794068
DOCNO: 10748669
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: toxicity
QUALIFIER: chemically induced
QUALIFIER: toxicity
QUALIFIER: prevention & control
QUALIFIER: etiology
AUTHOR: F Conso F
AFFILIATION: Département universitaire de médecine du travail, Faculté Cochin-Port-Royal, Paris.
PUBTYPE: Journal Article
JOURNALTITLE: La Revue du praticien.
COUNTRY: FRANCE
TITLE: [Recent advances in environmental toxicology]
PUBDATE: 20000201
Among the sanitary effects of environmental chemicals, 3 examples illustrate the complexity of the issues to be solved: 1. endocrine disrupters, xenobiotics which interfere with hormonal systems, could increase the risk of reproductive and developmental disturbances and explain the rising incidence of hormone-dependent cancers; 2. multiple chemical sensitivity due to odorous chemicals has severe social consequences and warrants further research; 3. the reappearance of well-known poisoning cases and the emergent new toxic diseases due to substitutive products for solvents, cooling agents and spray propellants banned for ecological purpose, demonstrate the need for surveillance programmes of industrial and household products.

12. DOCID:27326 SCORE: 0.00217171688181498
DOCNO: 10950238
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: analogs & derivatives
QUALIFIER: drug effects
QUALIFIER: therapeutic use
AUTHOR: R Govindarajan R
AUTHOR: K M Heaton KM
AUTHOR: R Broadwater R
AUTHOR: A Zeitlin A
AUTHOR: N P Lang NP
AUTHOR: M Hauer-Jensen M
PUBTYPE: Clinical Trial
PUBTYPE: Letter
JOURNALTITLE: Lancet.
COUNTRY: ENGLAND
TITLE: Effect of thalidomide on gastrointestinal toxic effects of irinotecan.
PUBDATE: 20000801
Irinotecan is the only accepted second-line treatment for colorectal cancer in the USA. Doses are, however, frequently limited by associated late-onset diarrhoea. Thalidomide has antiangiogenic and immunomodulatory properties and is being investigated as an antineoplastic. We did a pilot study of combination therapy with thalidomide and irinotecan for metastatic colorectal cancer. In an interim analysis of nine patients, thalidomide had almost eliminated the dose-limiting gastrointestinal toxic effects of irinotecan, especially diarrhoea and nausea (each p<0.0001), and eight of nine patients were able to complete the chemotherapy course.

13. DOCID:25351 SCORE: 0.00215675182491268
DOCNO: 11001067
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Neovascularization, Physiologic
QUALIFIER: physiology
QUALIFIER: physiology
AUTHOR: G D Yancopoulos GD
AUTHOR: S Davis S
AUTHOR: N W Gale NW
AUTHOR: J S Rudge JS
AUTHOR: S J Wiegand SJ
AUTHOR: J Holash J
AFFILIATION: Regeneron Pharmacueticals, Inc., Tarrytown, New York 10591, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Nature.
COUNTRY: ENGLAND
TITLE: Vascular-specific growth factors and blood vessel formation.
PUBDATE: 20000901
A recent explosion in newly discovered vascular growth factors has coincided with exploitation of powerful new genetic approaches for studying vascular development. An emerging rule is that all of these factors must be used in perfect harmony to form functional vessels. These new findings also demand re-evaluation of therapeutic efforts aimed at regulating blood vessel growth in ischaemia, cancer and other pathological settings.

14. DOCID:27430 SCORE: 0.00212635352897322
DOCNO: 11601068
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: epidemiology
AUTHOR: A J Sasco AJ
AFFILIATION: L'unité d'épidémiologie pour la prévention du cancer au centre international de recherche sur le cancer, recherche à l'Institut national de la santé et de la recherche médicale 150, cours Albert-Thomas 69372 Lyon. sasco@iarc.fr
PUBTYPE: Journal Article
JOURNALTITLE: La Revue du praticien.
COUNTRY: France
TITLE: [Epidemiology of uterine cancers]
PUBDATE: 20010901
Uterine cancers comprise 2 distinct pathological entities: cancer of the cervix and cancer of the corpus. They differ both in descriptive and etiologic epidemiology. Cervical cancer is more frequent in the developing world, is decreasing in terms of incidence and even more mortality in many countries and has essentially a viral etiology, being linked to human papilloma viruses. Cancer of the uterine corpus is more frequent in the developed world, is rather stable in terms of incidence and mostly has a hormonal etiology.