0. DOCID:21756 SCORE: 0.00300160235496145
DOCNO: 9136458
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
AUTHOR: N G Huilgol NG
AUTHOR: M M Khan MM
AUTHOR: R Puniyani R
AFFILIATION: Division of Radiation Oncology, Dr. Balabhai Nanavati Hospital & Medical Center, Bombay.
PUBTYPE: Clinical Trial
PUBTYPE: Controlled Clinical Trial
PUBTYPE: Journal Article
JOURNALTITLE: Indian journal of cancer.
COUNTRY: INDIA
TITLE: Capillary perfusion--a study in two groups of radiated patients for cancer of head and neck.
PUBDATE: 19950601
Laser Doppler velocitometry is novel non-invasive technique to assess cutaneous microcirculation. Patients undergoing radiation therapy for head and neck cancer with convention and accelerated fraction action were evaluated under normal condition before and after radiation. A total of 70 sites in group A (conventional fractionation) and 35 sites in group B (accelerated fractionation were evaluated. Increase in perfusion was noted in patients undergoing radiation with accelerated fractionation.


1. DOCID:23630 SCORE: 0.00256107479477434
DOCNO: 8825571
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: veterinary
QUALIFIER: veterinary
QUALIFIER: surgery
QUALIFIER: therapy
QUALIFIER: veterinary
QUALIFIER: veterinary
AUTHOR: E G MacEwen EG
AUTHOR: I D Kurzman ID
AFFILIATION: Department of Medical Sciences, University of Wisconsin, Madison 53706, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The Veterinary clinics of North America. Small animal practice.
COUNTRY: UNITED STATES
TITLE: Canine osteosarcoma: amputation and chemoimmunotherapy.
PUBDATE: 19960101
Canine osteosarcoma is a highly metastatic cancer commonly seen in large breed dogs. At the time of diagnosis, approximately 90% to 95% of the dogs have established micrometastases. Dogs undergoing amputation alone have a median survival time of 3 to 4 months. Amputation followed by cisplatin chemotherapy increases median survival times to 9 to 11 months. When dogs are treated with amputation and cisplatin, followed by immunotherapy (with liposome-encapsulated muramyl tripeptide phosphatidylethanolamine), median survival times increase to 14.4 months, the longest reported median survival time for dogs with osteosarcoma treated by amputation and any form of adjuvant therapy.


2. DOCID:22575 SCORE: 0.00254010779188935
DOCNO: 7731639
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Breast Neoplasms
DESCRIPTOR: Carcinoma in Situ
DESCRIPTOR: Carcinoma, Ductal, Breast
AUTHOR: M J Silverstein MJ
AFFILIATION: Breast Center, Van Nuys, California, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Obstetrics and gynecology clinics of North America.
COUNTRY: UNITED STATES
TITLE: Noninvasive breast cancer. The dilemma of the 1990s.
PUBDATE: 19941201
The most profound impact in the field of breast cancer during the last 15 years has been the development and acceptance of screening mammography: a test capable of finding nonpalpable cancer years before it would have become clinically evident. Many of these nonpalpable lesions are noninvasive; many of them are not even real cancers. The spectrum of treatment for noninvasive breast cancer runs from nothing more than excisional biopsy to bilateral mastectomy. No wonder noninvasive breast cancer is one of the most confusing problems in oncology today, for both patients and physicians.


3. DOCID:23664 SCORE: 0.00241929106014584
DOCNO: 7600538
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: DNA Damage
DESCRIPTOR: Oxidative Stress
QUALIFIER: toxicity
QUALIFIER: toxicity
AUTHOR: H Wiseman H
AUTHOR: H Kaur H
AUTHOR: B Halliwell B
AFFILIATION: Department of Nutrition and Dietetics, King's College London, Kensington, UK.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Cancer letters.
COUNTRY: IRELAND
TITLE: DNA damage and cancer: measurement and mechanism.
PUBDATE: 19950601
There is currently great interest in the possible role of reactive nitrogen species and reactive oxygen species in causing DNA damage that leads to cancer. It appears likely that certain reactive oxygen species can act as complete carcinogens. However, the development of human cancer will depend on other factors such as the extent of DNA damage, antioxidant levels and DNA repair systems. The true picture will only be seen if we have reliable and sensitive techniques for the measurement of DNA damage. In this article we outline various methods for measuring DNA damage base, with special emphasis on HPLC and GC-MS based systems.


4. DOCID:21838 SCORE: 0.00221611645118611
DOCNO: 8618405
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
QUALIFIER: therapy
AUTHOR: H Takita H
AFFILIATION: Department of Thoracic Surgery and Oncology, Roswell Park Cancer Institute, New York State Department of Health, Buffalo 14263, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Journal of surgical oncology.
COUNTRY: UNITED STATES
TITLE: Perioperative therapy for locoregional nonsmall-cell lung cancer.
PUBDATE: 19960501
Surgical therapy remains the treatment of choice for resectable nonsmall-cell lung cancer (NSCLC). However, the 5-year survival results of surgical therapy is 40-70%, which is far from acceptable. In this report, past results of perioperative therapies were reviewed to identify the future direction of effort in improving the therapy of NSCLC. Two perioperative modes of treatment that may possibly improve postsurgical survival were identified, i.e., neoadjuvant chemotherapy for resectable NSCLC and postoperative specific active immunotherapy.


5. DOCID:21827 SCORE: 0.00221611172589764
DOCNO: 8022070
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Atrioventricular Node
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: H Kawano H
AUTHOR: R Okada R
AUTHOR: Y Kawano Y
AUTHOR: T Tokano T
AUTHOR: M Sumiyoshi M
AUTHOR: Y Nakazato Y
AUTHOR: Y Nakata Y
AUTHOR: H Yamaguchi H
AUTHOR: T Shirai T
AFFILIATION: Research Laboratory for Cardiovascular Pathology, Juntendo University School of Medicine, Tokyo, Japan.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Japanese heart journal.
COUNTRY: JAPAN
TITLE: Mesothelioma in the atrioventricular node. Case report.
PUBDATE: 19940301
A patient with complete atrioventricular block and an implanted permanent pacemaker died of colon cancer at the age of 64 years. At autopsy, a cardiac tumor in the region of the atrioventricular node (mesothelioma of the atrioventricular node) was found. The origin of this type of tumor is controversial. Histochemical findings suggested that the tumor in this case was of endodermal origin.


6. DOCID:20542 SCORE: 0.00209515879762345
DOCNO: 8823770
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: secondary
AUTHOR: A Das A
AUTHOR: F H Hochberg FH
AFFILIATION: Department of Neurology, Massachusetts General Hospital, Boston, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Neurosurgery clinics of North America.
COUNTRY: UNITED STATES
TITLE: Clinical presentation of intracranial metastases.
PUBDATE: 19960701
Intracranial metastases are the single most costly neurologic ailment. This article provides the clinician with detailed statements of the patterns of their appearance and tumors of origin. Most common causative cancers are of lung, breast, or melanoma origin. Aggressive therapies carry with them the risk of nervous system dissemination of rare tumors, remote complications of these cancers and the morbidity of therapy.


7. DOCID:23313 SCORE: 0.0020524516426229
DOCNO: 9294342
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Arachnoid
DESCRIPTOR: Pia Mater
QUALIFIER: secondary
QUALIFIER: secondary
QUALIFIER: pathology
QUALIFIER: etiology
AUTHOR: J J Chua JJ
AUTHOR: P K Tan PK
AUTHOR: W T Seow WT
AFFILIATION: Department of Surgery Tan Tock Seng Hospital, Singapore.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Singapore medical journal.
COUNTRY: SINGAPORE
TITLE: Leptomeningeal metastasis with urological presentation.
PUBDATE: 19970601
The incidence of clinical leptomeningeal metastases from non-neurologic solid tumour is generally increasing as a result of better survival of systemic cancer with chemotherapy. Their presentation varies according to the neurological involvement. A case of leptomeningeal metastasis from an unknown primary source presenting with urinary incontinence as the sole complaint is reported. While urinary incontinence is common in the community and is often functional, neurogenic causes must also be considered. Urodynamic study and electrophysiological assessment are useful investigations in the exclusion of a neurogenic cause. An MRI of the spine will be required to define any anatomic lesion.


8. DOCID:20297 SCORE: 0.00204968281261697
DOCNO: 7582586
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: ultrasonography
QUALIFIER: surgery
AUTHOR: C J Lightdale CJ
AFFILIATION: Columbia University, College of Physicians and Surgeons, Columbia-Presbyterian Medical Center, New York, New York, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Gastrointestinal endoscopy clinics of North America.
COUNTRY: UNITED STATES
TITLE: Detection of anastomotic recurrence by endoscopic ultrasonography.
PUBDATE: 19950701
There seems little doubt that endoscopic ultrasonography is highly sensitive and significantly better than computed tomography for the diagnosis of recurrent cancer at the surgical anastomosis after resection of esophageal and gastric cancer. The impact of using EUS for this purpose is discussed.


9. DOCID:22114 SCORE: 0.00200595651543378
DOCNO: 8995110
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: W M Weinstein WM
AFFILIATION: Department of Medicine, University of California at Los Angeles Center for the Health Sciences, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Gastrointestinal endoscopy clinics of North America.
COUNTRY: UNITED STATES
TITLE: Precursor lesions for cancer of the cardia.
PUBDATE: 19970101
This article gives the rationale for the likelihood that the precursor lesion for cancer of the cardia is either short segments of Barrett's esophagus or even intestinalized (globlet cell change) mucosa at a normally located squamo-columnar junction. Intestinal metaplasia of the cardia is likely a wear and tear phenomenon in many individuals without gastroesophageal reflux disease (GERD). Markers that stratify risk further are required before routine biopsy specimens of the Z-line can be obtained in the clinical evaluation of patients with GERD.


10. DOCID:23818 SCORE: 0.00194877845982663
DOCNO: 9103006
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: genetics
AUTHOR: S O Kolset SO
AUTHOR: C A Drevon CA
AUTHOR: K Prydz K
AFFILIATION: Institutt for ernaeringsforskning, Universitetet i Oslo, Blindern.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Tidsskrift for den Norske laegeforening.
COUNTRY: NORWAY
TITLE: [Proteoglycans and pathology--new aspects]
PUBDATE: 19970301
It is well documented that proteoglycans are involved in a wide range of pathological conditions. Recently published results in international journals provide new information on the role of proteoglycans in such conditions. A mutation in the gene encoding for a cell surface proteoglycan has been demonstrated in overgrowth syndromes. A proteoglycan has been isolated from urine and shown to induce cachexia in cancer patients. Furthermore, in both achondrogenesis and colon cancer, the reduced ability to sulphate proteoglycans is due to genetic defects in cellular sulfate transporters. Finally, fibrosis has been inhibited in glomerulonephritic mice by transferring the gene for decorin, a transforming growth factor beta-1 binding proteoglycan, into muscle tissue.


11. DOCID:23319 SCORE: 0.00194331218672455
DOCNO: 9033377
AUTHOR: C M Furnival CM
AFFILIATION: Wesley Medical Centre, Auchenflower, Brisbane, Queensland, Australia.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The Australian and New Zealand journal of surgery.
COUNTRY: AUSTRALIA
TITLE: Breast cancer: current issues in diagnosis and treatment.
PUBDATE: 19970101
The diagnosis and treatment of breast cancer in Australia has changed in response to new technologies and cultural influences which have emphasized the importance of psychological and social aspects of breast cancer. In this review article, recent developments are examined in relation to current surgical practice. Changes in the incidence of breast cancer, the effect of mammographic screening on the outcome of treatment, the increasing use of breast-conserving surgery, the timing of surgery in relation to the menstrual cycle and the importance of risk factors for breast cancer are all considered. Breast cancer is a potentially curable disease. Early detection and conservative surgery provide a framework for disease control.


12. DOCID:21310 SCORE: 0.00192780516095811
DOCNO: 9238925
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: G H Knowles GH
AUTHOR: D I Jodrell DI
AFFILIATION: Imperial Cancer Research Fund, Department of Clinical Oncology, Western General Hospital, Edinburgh.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: European journal of cancer care.
COUNTRY: ENGLAND
TITLE: Recent developments in adjuvant chemotherapy for colorectal cancer.
PUBDATE: 19970301
Recent developments in the use of systemic chemotherapy and intraportal chemotherapy in the treatment for colorectal cancer suggests that a reduction in mortality is achievable. This paper provides an overview of the management of colorectal cancer and the rationale behind adjuvant chemotherapy. A review of the current research literature published from both America and Europe will follow. Finally, the limitations and implications of the reviewed data will be discussed.


13. DOCID:23784 SCORE: 0.00191714004506932
DOCNO: 8079172
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: chemistry
QUALIFIER: analogs & derivatives
QUALIFIER: metabolism
QUALIFIER: chemistry
QUALIFIER: metabolism
AUTHOR: A K Chaudhary AK
AUTHOR: M Nokubo M
AUTHOR: G R Reddy GR
AUTHOR: S N Yeola SN
AUTHOR: J D Morrow JD
AUTHOR: I A Blair IA
AUTHOR: L J Marnett LJ
AFFILIATION: A. B. Hancock Jr. Memorial Laboratory for Cancer Research, Vanderbilt University School of Medicine, Nashville, TN 37232-0146.
PUBTYPE: Journal Article
JOURNALTITLE: Science.
COUNTRY: UNITED STATES
TITLE: Detection of endogenous malondialdehyde-deoxyguanosine adducts in human liver.
PUBDATE: 19940901
Endogenous DNA adducts may contribute to the etiology of human genetic disease and cancer. One potential source of endogenous DNA adducts is lipid peroxidation, which generates mutagenic carbonyl compounds such as malondialdehyde. A sensitive mass spectrometric method permitted detection and quantitation of the major malondialdehyde-DNA adduct, a pyrimidopurinone derived from deoxyguanosine. DNA from disease-free human liver was found to contain 5400 adducts per cell, a frequency comparable to that of adducts formed by exogenous carcinogens.


14. DOCID:23480 SCORE: 0.00190408273420017
DOCNO: 8291659
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: W Van de Voorde W
AUTHOR: H Van Poppel H
AUTHOR: K Haustermans K
AUTHOR: L Baert L
AUTHOR: J Lauweryns J
AFFILIATION: Department of Pathology I, University Hospitals, Katholieke Universiteit, Leuven, Belgium.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: The American journal of surgical pathology.
COUNTRY: UNITED STATES
TITLE: Mucin-secreting adenocarcinoma of the prostate with neuroendocrine differentiation and Paneth-like cells.
PUBDATE: 19940201
We present an unusual variant of prostatic adenocarcinoma with obvious mucinous and neuroendocrine features, arising in the transition zone. The neuroendocrine component is largely represented by Paneth-like cells (PLCs). These cells correspond to previously described eosinophilic cells and are amphicrine. We could demonstrate immunohistochemically the presence of calcitonin in some of these PLCs. The prognostic significance of these special characteristics is not well known, but it is most likely that this type of prostate cancer will not respond well to hormonal therapy.