0. DOCID:11941 SCORE: 0.0036501672262141
DOCNO: 7077060
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: diagnosis
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: T L Fabry TL
AUTHOR: A Frankel A
AUTHOR: J D Waye JD
PUBTYPE: Journal Article
JOURNALTITLE: Journal of clinical gastroenterology.
COUNTRY: UNITED STATES
TITLE: Gastric polyps.
PUBDATE: 19820201
We suggest an approach to patients with gastric polyps, based on a study of 73 patients seen at this institution over a 5-year period. There were 40 cases of adenomatous and 20 cases of hamartomatous polyps. Differentiation between these two groups of polyps was not possible on the basis of clinical presentation, laboratory data, radiological, or endoscopic appearance. Differentiation was possible only on histologic examination of a totally resected specimen. In this series, only the adenomatous polyps were associated with gastric cancers in five patients. Since the malignancy either preceded or followed the recognition of adenomatous polyps, it is important to establish an early definite histological diagnosis. Patients with known adenomatous polyps should be followed closely for the development of gastric carcinoma, even after the polyps have been removed.

1. DOCID:10881 SCORE: 0.00347466150294851
DOCNO: 6323872
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: metabolism
QUALIFIER: metabolism
QUALIFIER: metabolism
QUALIFIER: metabolism
QUALIFIER: metabolism
AUTHOR: H Fleming H
AUTHOR: R Blumenthal R
AUTHOR: E Gurpide E
PUBTYPE: Journal Article
JOURNALTITLE: Journal of steroid biochemistry.
COUNTRY: ENGLAND
TITLE: Characteristics of cyclic nucleotide dependent regulation of cytoplasmic E2 binders in cultured endometrial and breast cells.
PUBDATE: 19840101
Estradiol binding levels have previously been shown to be increased or decreased by the addition of of cGMP or cAMP respectively to cellular homogenates prepared from human endometrial tissue or from the endometrial cell line HEC 1. Similar cyclic nucleotide dependent effects have now been demonstrated in homogenates prepared from a second endometrial cell line, HEC 50, and from two breast cancer cell lines, CG-5 and T47D. It was previously shown that ATP and Mg2+ are necessary for the generation or inactivation of E2 binding sites. The present study demonstrates that the concentration of K+ and of dithiothreitol can also affect these reactions.

2. DOCID:11690 SCORE: 0.00306679603860673
DOCNO: 6231185
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: R Abele R
AUTHOR: E Kaplan E
AUTHOR: R Grossenbacher R
AUTHOR: H J Schmid HJ
AUTHOR: F Cavalli F
PUBTYPE: Journal Article
JOURNALTITLE: European journal of cancer & clinical oncology.
COUNTRY: ENGLAND
TITLE: Phase II study of doxifluridine in advanced squamous cell carcinoma of the head and neck.
PUBDATE: 19840301
We conducted a phase II trial with 5'-deoxy-5-fluoridine (doxifluridine) in advanced squamous cell carcinoma of the head and neck. The drug was given at the dose of 4 g/m2 daily X 5 every 3 weeks. Twenty eligible patients entered this trial, 12 being evaluable for response to doxifluridine. The majority of these patients received previous treatment for cancer. One complete and two partial remissions were observed (25%). Drug-induced toxicity consisted mainly of myelosuppression, mild nausea and vomiting, stomatitis and central nervous system side-effects. Other dosages or schedules for doxifluridine administration might be explored in poor-risk patients.

3. DOCID:14993 SCORE: 0.00295934558160644
DOCNO: 2765765
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: mortality
QUALIFIER: mortality
QUALIFIER: mortality
AUTHOR: Z Kirkali Z
AUTHOR: L E Moffat LE
AUTHOR: R F Deane RF
AUTHOR: K F Kyle KF
AUTHOR: A G Graham AG
AFFILIATION: Department of Urology, Western Infirmary, Glasgow.
PUBTYPE: Journal Article
JOURNALTITLE: British journal of urology.
COUNTRY: ENGLAND
TITLE: Urothelial tumours of the upper urinary tract.
PUBDATE: 19890701
We present a retrospective 10 year analysis of 76 patients with urothelial tumours of the upper urinary tract. Patients older than 65 years, and female patients, presented with more advanced stages and had a worse prognosis. The grade and stage of the tumour has the greatest impact on survival. No conclusions can be drawn on the efficacy of various types of surgery, but simple nephrectomy gave a 5-year survival of 68%, with a stump recurrence rate of 15%. We observed that patients with urothelial tumours had 4 fold increased chance of developing gastrointestinal cancer.

4. DOCID:11819 SCORE: 0.00273972049329066
DOCNO: 4014150
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: methods
QUALIFIER: mortality
AUTHOR: R Brookmeyer R
AUTHOR: N Day N
AUTHOR: V Pompe-Kirn V
PUBTYPE: Journal Article
JOURNALTITLE: American journal of epidemiology.
COUNTRY: UNITED STATES
TITLE: Assessing the impact of additional follow-up in cohort studies.
PUBDATE: 19850401
An approach is described for predicting the statistical value of extending follow-up in a cohort study. A simple approximation to the expected number of new events of interest is given. The effect of these events on inferences for parameters such as a standardized mortality ratio is approached in two ways. The first concerns the probability of reversing the conclusion of a significance test. The second approach finds the plausible range of values for the standardized mortality ratio after further follow-up that are consistent with the currently available data. Each of these values is displayed together with the precision of the estimate. The methods are illustrated with results from the International Radiation Study of Cervical Cancer (IARC Scientific Publication No. 52, 1984).

5. DOCID:13938 SCORE: 0.00273804944884876
DOCNO: 2632037
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: B N Zhang BN
PUBTYPE: Journal Article
JOURNALTITLE: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases.
COUNTRY: CHINA
TITLE: [Tuberculosis of the breast misdiagnosed as breast cancer]
PUBDATE: 19891001
The authors report 15 patients with tuberculosis of the breast initially misdiagnosed as breast cancers. Criteria of differentiation of breast tuberculosis were: incidence (Tbc: cancer = 1: 245), lacking in constant site of involvement, possible concomitant involvement of other organs, eg. lung tuberculosis, youth of the patient, multi-para and history of breast feeding, in isolated cases, co-existence of tuberculosis and cancer is not impossible. The authors stress meticulous care in evaluating the history, symptoms, signs and supplementary examinations. Needle biopsy and pathology are indicated.

6. DOCID:10497 SCORE: 0.00272209259556745
DOCNO: 6632211
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Bile Ducts, Intrahepatic
QUALIFIER: pathology
AUTHOR: M Kurashina M
AUTHOR: S Kozuka S
AUTHOR: N Nakashima N
AUTHOR: N Hirabayashi N
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [Mode of spread of intrahepatic bile duct carcinoma]
PUBDATE: 19830901
To determine the area of surgical resection and the prognosis in patients with intrahepatic bile duct carcinoma, we studied the mode of spread of this cancer, using 27 autopsy and 4 lobectomized cases. In hilar carcinoma, there was lymphatic invasion to the extrahepatic bile duct before invation to the hepatic lobules. Scirrhous cancer spread more distantly toward the peripheral areas of the liver than non-scirrhous cancer. The occurrence of extrahepatic metastasis might involve the following factors; depth of infiltration, extent of venous invasion, intrahepatic metastasis, size of the main tumor, and number of hepatic segments invaded by the cancer.

7. DOCID:15781 SCORE: 0.0027215425465512
DOCNO: 2758914
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: G Z Zhu GZ
PUBTYPE: Journal Article
JOURNALTITLE: Zhonghua fu chan ke za zhi.
COUNTRY: CHINA
TITLE: [Endometrioid carcinoma of the ovary: clinicopathologic analysis in 87 cases]
PUBDATE: 19890301
From Jan. 1972 through Dec. 1984, 87 cases of endometrioid carcinoma of ovary were treated in our hospital, accounting for 23.5% of all cases of epithelial ovarian cancer admitted during the same period. Histologically they could be subdivided into 4 types, i. e. endometrioid carcinoma, clear cell carcinoma, adenocanthoma, and adenosquamous carcinoma. The 5-year survival rates for each type of tumors were 51.2, 0, 100 and 0% respectively. The 5- and 10-year survival rates were 90.1 and 90.1% for stage I, patients, 23.3 and 23.3% for stage II, 4.6 and 0% for stage III, and nil for stage IV. For improving the survival rate and reducing the incidence of recurrence, postoperative long term hormonal therapy should be considered.

8. DOCID:11379 SCORE: 0.00269233034147727
DOCNO: 6546732
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: therapy
AUTHOR: J Menczer J
AUTHOR: G Ben-Baruch G
AUTHOR: M Modan M
AUTHOR: J Brenner J
AUTHOR: H Brenner H
PUBTYPE: Journal Article
JOURNALTITLE: Gynecologic oncology.
COUNTRY: UNITED STATES
TITLE: A comparison of postoperative radiotherapy with postoperative chemotherapy in stage II-IV ovarian cancer patients.
PUBDATE: 19840201
A retrospective comparison between 28 stage II-IV ovarian cancer patients who received postoperative abdominopelvic irradiation and 15 such patients who received postoperative cis-platinum, Adriamycin, and Cytoxan chemotherapy was made. In both treatment groups there was a trend for a longer progression-free interval and 3-year survival in patients with residual tumor masses of less than 2 cm in diameter. In these patients there was also a trend favoring radiotherapy. However, all differences were not significant. Criteria for the choice of either modality of postoperative therapy of ovarian cancer patients remain to be determined. Nevertheless, the efficacy of both modes of treatment does not differ greatly.

9. DOCID:14831 SCORE: 0.00268448543488949
DOCNO: 2680304
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Kidney Neoplasms
DESCRIPTOR: Scalp
QUALIFIER: secondary
QUALIFIER: secondary
AUTHOR: A Menter A
AUTHOR: A S Boyd AS
AUTHOR: D M McCaffree DM
AFFILIATION: Department of Internal Medicine, Baylor University Medical Center, Dallas, Texas 75246.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Cutis; cutaneous medicine for the practitioner.
COUNTRY: UNITED STATES
TITLE: Recurrent renal cell carcinoma presenting as skin nodules: two case reports and review of the literature.
PUBDATE: 19891001
The skin is a relatively rare site for metastatic carcinoma compared to other organs such as bone, lung, and liver. Once it is discovered, however, the underlying disease has usually become widespread. We describe two patients with recurrent renal cell carcinoma who presented with skin nodules six and ten years, respectively, after their initial cancers were diagnosed. Treatment options and prognostic factors are outlined and dermatologists are urged to consider neoplastic disease when confronted with patients presenting with acute, asymptomatic skin nodules.

10. DOCID:15020 SCORE: 0.00265281092964191
DOCNO: 2823678
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: etiology
QUALIFIER: complications
QUALIFIER: etiology
AUTHOR: M G Wyatt MG
AUTHOR: P W Houghton PW
AUTHOR: N J Mortensen NJ
AUTHOR: R C Williamson RC
AFFILIATION: University Department of Surgery, Bristol Royal Infirmary.
PUBTYPE: Journal Article
JOURNALTITLE: Annals of the Royal College of Surgeons of England.
COUNTRY: ENGLAND
TITLE: The malignant potential of colorectal Crohn's disease.
PUBDATE: 19870901
Six patients developed colorectal carcinoma in association with Crohn's disease. The cancer was diagnosed at a mean age of 46 years and a mean 19 years after the onset of Crohn's disease. Five carcinomas arose in the chronically inflamed segment of bowel, while a sixth arose in caecum previously bypassed for Crohn's ileitis. Four carcinomas were mucinous, four presented with fistula and four were treated by complete removal of the large intestine. Three patients have died of residual or recurrent cancer. The data support an aetiological link between Crohn's proctocolitis and carcinoma.

11. DOCID:11190 SCORE: 0.00262680230432416
DOCNO: 4071330
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: African Continental Ancestry Group
DESCRIPTOR: European Continental Ancestry Group
QUALIFIER: pathology
AUTHOR: R J Pegoraro RJ
AUTHOR: D Nirmul D
AUTHOR: J V Bryer JV
AUTHOR: J P Jordaan JP
AUTHOR: S M Joubert SM
PUBTYPE: Journal Article
JOURNALTITLE: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.
COUNTRY: SOUTH AFRICA
TITLE: Clinical patterns of presentation of breast cancer in women of different racial groups in South Africa.
PUBDATE: 19851101
The ages at presentation of white patients with breast cancer were found to be significantly higher than those of blacks, Indians and coloureds; 73% of white women fell into the postmenopausal group, in marked contrast to only 35% of Indians, while blacks and coloureds had similar proportions of pre- and post-menopausal patients. A significantly higher incidence of poorly differentiated tumours was seen in Indian and black patients. Blacks showed a significant tendency to present with more advanced disease, while whites were generally diagnosed at a much earlier stage.

12. DOCID:9222 SCORE: 0.00260133026249239
DOCNO: 3843375
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: chemically induced
QUALIFIER: chemically induced
AUTHOR: S K Hoar SK
AUTHOR: J Santodonato J
AUTHOR: T P Cameron TP
AUTHOR: M I Kelsey MI
PUBTYPE: Journal Article
JOURNALTITLE: Journal of occupational medicine. : official publication of the Industrial Medical Association.
COUNTRY: UNITED STATES
TITLE: Monographs on human exposures to chemicals in the workplace.
PUBDATE: 19850801
The National Cancer Institute has contracted with Syracuse Research Corporation to produce monographs on the potential hazards of human exposure to approximately 70 chemicals used in the workplace. The monographs include detailed exposure data for specific job categories, as well as summaries of chemical and physical data, animal and human toxicological studies, short-term assays, and epidemiologic data. The information is useful for identifying suitable populations for epidemiologic research.

13. DOCID:10697 SCORE: 0.00257840146456463
DOCNO: 6617281
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: secondary
AUTHOR: J R Jett JR
AUTHOR: C G Hollinger CG
AUTHOR: A R Zinsmeister AR
AUTHOR: P C Pairolero PC
PUBTYPE: Journal Article
JOURNALTITLE: Chest.
COUNTRY: UNITED STATES
TITLE: Pulmonary resection of metastatic renal cell carcinoma.
PUBDATE: 19831001
Over a ten-year period, 44 patients with known primary renal cell cancer underwent thoracotomy for pulmonary metastases. The median postthoracotomy survival for all patients was 33 months. The five-year survival was 27 percent. Postthoracotomy survival was significantly better in those patients with a disease free interval of greater than 24 months and patients with metastatic lesions greater than or equal to 3 cm. No difference in survival was detected in patients with one versus more than one lesion or in patients undergoing complete resection versus incomplete resection or biopsy only. Age, sex, grade of tumor, or location of the pulmonary metastasis had no influence on survival.

14. DOCID:13037 SCORE: 0.002551816104612
DOCNO: 3469806
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: O Bertetto O
AUTHOR: V Dongiovanni V
AUTHOR: M Clerico M
AUTHOR: A Calciati A
PUBTYPE: Journal Article
JOURNALTITLE: Tumori.
COUNTRY: ITALY
TITLE: Phase II trial of weekly 4-epi-doxorubicin (epirubicin) in squamous cell carcinoma of the head and neck.
PUBDATE: 19870201
We tested 4'-epi-doxorubicin (epirubicin) in 15 patients with advanced squamous cell carcinoma of the head and neck which progressed after conventional therapy. The drug was administered at the dosage of 25 mg/m2 weekly. No patient achieved objective response. Toxicity was minimal. Epirubicin given at this dose and schedule revealed no activity in heavily pretreated patients with cancer of the head and neck.