0. DOCID:17933 SCORE: 0.00544580033304978
DOCNO: 1372399
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: complications
QUALIFIER: etiology
QUALIFIER: etiology
AUTHOR: J B Epstein JB
AUTHOR: S Silverman S
AFFILIATION: Division of Dentistry, British Columbia Cancer Agency, Vancouver, Canada.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Oral surgery, oral medicine, and oral pathology.
COUNTRY: UNITED STATES
TITLE: Head and neck malignancies associated with HIV infection.
PUBDATE: 19920201
Immunosuppressed persons are at greater risk of developing malignancies. In human immunodeficiency virus (HIV) immunosuppression the most common oral cancers are Kaposi's sarcoma and non-Hodgkin's lymphoma. Squamous cell carcinoma has also been reported to be associated with HIV disease. Kaposi's sarcoma is the most frequent neoplastic disease in acquired immunodeficiency syndrome and is by far the most common in the head and neck area. This article reviews the prevalence, clinical features, and management of these diseases in HIV infection.


1. DOCID:22554 SCORE: 0.0049090874355458
DOCNO: 8984148
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: chemistry
QUALIFIER: isolation & purification
QUALIFIER: pharmacology
QUALIFIER: isolation & purification
QUALIFIER: pharmacology
AUTHOR: J H Sheu JH
AUTHOR: S Y Huang SY
AUTHOR: C Y Duh CY
AFFILIATION: Department of Marine Resources, National Sun Yat-Sen University, Taiwan, Republic of China.
PUBTYPE: Journal Article
JOURNALTITLE: Journal of natural products.
COUNTRY: UNITED STATES
TITLE: Cytotoxic oxygenated desmosterols of the red alga Galaxaura marginata.
PUBDATE: 19960101
Desmosterol (1), 24,25-epoxycholesterol (2), 24-hydroperoxycholesta-5,25-dien-3 beta-ol (3), 25-hydroperoxycholesta-5,23(E)-dien-3 beta-ol (4), cholesta-5,25-diene-3 beta,24-diol (5), and 24,25-epoxy-6 beta-hydroxycholest-4-en-3-one (7) were isolated from the marine red alga Galaxaura marginata; sterols 3, 4, and 7 were isolated for the first time from a natural source. Sterols 3-7 exhibited significant cytotoxicity toward several cancer cell lines.


2. DOCID:22600 SCORE: 0.00490908556665496
DOCNO: 9157516
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Gene Therapy
AUTHOR: P Moullier P
AUTHOR: N Ferry N
AUTHOR: J M Heard JM
AFFILIATION: Laboratoire de thérapie génique, CHU Hötel-Dieu, Nantes.
PUBTYPE: Journal Article
JOURNALTITLE: La Revue du praticien.
COUNTRY: FRANCE
TITLE: [Principles and stakes of gene therapy]
PUBDATE: 19970101
As the human genome sequencing expands and the molecular bases of diseases are better understood, the tools that allow gene packaging and transfer are available. Transferring a therapeutical gene becomes a reality and indeed more than 100 clinical protocols are currently exploring a variety of applications, from the inherited genetic diseases such as cystic fibrosis to the acquired ones such as cancer. Herein, we describe the different gene transfer strategies applied to animals and humans and we present the advantages and limitations of the currently available vectors which, today, represent the limiting factor for efficient gene therapy.


3. DOCID:19757 SCORE: 0.00482007106694167
DOCNO: 8371372
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Bladder
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: R J Hedden RJ
AUTHOR: N Husseinzadeh N
AUTHOR: R B Bracken RB
AFFILIATION: Department of Surgery, University of Cincinnati Medical Center, Ohio.
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of urology.
COUNTRY: UNITED STATES
TITLE: Bladder sparing surgery for locally advanced female urethral cancer.
PUBDATE: 19931001
Cystectomy remains one of the standard treatments for women with locally advanced (stage C) urethral cancer, or stage A or B lesions that have failed radiation therapy. Often, the urethral neoplasm does not invade the bladder. We treated 5 women with stage C urethral cancer by wide local excision with or without concomitant radiation therapy, while preserving the bladder. Local control was achieved in all patients with followup ranging from 4 to 75 months (median 42). We believe that bladder sparing treatment strategies should be considered for selected stage C tumors when the bladder is not invaded by the neoplasm.


4. DOCID:19482 SCORE: 0.00438316270256066
DOCNO: 1526520
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Uterine Cervical Neoplasms
QUALIFIER: secondary
QUALIFIER: secondary
QUALIFIER: secondary
AUTHOR: L Kumar L
AUTHOR: R K Tanwar RK
AUTHOR: S P Singh SP
AFFILIATION: Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, Ansari Nagar, New Delhi.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Gynecologic oncology.
COUNTRY: UNITED STATES
TITLE: Intracranial metastases from carcinoma cervix and review of literature.
PUBDATE: 19920901
Brain metastases from primary cervical carcinoma are uncommon. Only 41 cases have been reported so far in the English literature. We have seen 2 cases over the last 2 years among 481 patients with cervical cancer. Brain metastases developed 7 and 35 months after the primary diagnosis. One patient with solitary metastasis had no evidence of disease elsewhere and is free of disease after surgery and radiation therapy 7 months after the brain metastasis. Another patient with multiple brain metastases and cervical disease is alive 2 months after palliative radiation therapy.


5. DOCID:17885 SCORE: 0.00418667233431429
DOCNO: 1877115
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: administration & dosage
QUALIFIER: surgery
AUTHOR: H W Herr HW
AFFILIATION: Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York.
PUBTYPE: Journal Article
JOURNALTITLE: The Urologic clinics of North America.
COUNTRY: UNITED STATES
TITLE: Transurethral resection and intravesical therapy of superficial bladder tumors.
PUBDATE: 19910801
The treatment of superficial bladder cancer is aimed at eradicating existing disease, inhibiting tumor recurrence, and preventing progression to invasion or metastasis. Transurethral resection is the primary modality, with intravesical therapy used in some cases to kill residual overt or occult carcinoma and premalignant lesions. Among the agents tested extensively, BCG appears to be more effective than mitomycin C, doxorubicin, or thiotepa, especially against carcinoma in situ. A number of questions remain to be answered about the management of this disease.


6. DOCID:19909 SCORE: 0.00396748367295342
DOCNO: 2040753
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Models, Biological
DESCRIPTOR: Mohs Surgery
DESCRIPTOR: Teaching Materials
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: D J Leffell DJ
AFFILIATION: Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut 06510.
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of dermatologic surgery and oncology.
COUNTRY: UNITED STATES
TITLE: An educational device for Mohs micrographic surgery. A three-dimensional model of basal cell carcinoma.
PUBDATE: 19910601
Mohs micrographic surgery for skin cancer (fresh-tissue technique) involves the processing of tissue in a complex fashion. The advantages of this method relate to the asymmetric three-dimensional growth of basal cell carcinoma (BCC). A device is described here based on published knowledge about the growth of BCC. The model demonstrates the precise way in which Mohs surgery varies from other surgical approaches to yield higher cure rates in specific circumstances. This device may be helpful in educating residents and medical students about Mohs surgery and in preparing patients for this procedure.


7. DOCID:16860 SCORE: 0.0039081662091143
DOCNO: 1692981
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: blood
QUALIFIER: diagnosis
QUALIFIER: blood
AUTHOR: G P Manca GP
AFFILIATION: Divisione di Urologia, U.S.S.L. n. 22, Ospedale Civile, Sondrio.
PUBTYPE: Journal Article
JOURNALTITLE: Minerva medica.
COUNTRY: ITALY
TITLE: [The role of PSA in prostatic adenocarcinoma]
PUBDATE: 19900401
The introduction of new tumours markers poses the problem of assessing their real predictive power and of considering all their possible uses. The following questions have been examined: 1) is PSA able to offer early diagnosis of prostate Ca 2) is there a relationship between cancer grading and PSA levels? 3) is it possible to use PSA to monitor patients under treatment? 4) can PSA predict the existence of bone metastasis?


8. DOCID:22134 SCORE: 0.00355432527794318
DOCNO: 10153735
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: legislation & jurisprudence
QUALIFIER: legislation & jurisprudence
QUALIFIER: economics
AUTHOR: E Brown E
PUBTYPE: Journal Article
JOURNALTITLE: Physician executive.
COUNTRY: UNITED STATES
TITLE: The medical device payment controversy rages on.
PUBDATE: 19951101
Who will pay for investigational research? This seemingly endless debate assumes different guises as different aspects of the health care industry come under scrutiny. The latest wrinkle in the debate involves reimbursement for devices that are not FDA approved. My September column discussed the issue of funding investigational cancer therapies, specifically high-dose therapy and bone marrow transplant, as treatments for various malignancies. That controversy was centered on the use of FDA-approved drugs in settings beyond the labeled indications. However, the issue with medical devices is different. It involves implantable devices that the FDA says have not proven to be safe and effective.


9. DOCID:18280 SCORE: 0.00348908056530081
DOCNO: 2249312
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: chemistry
QUALIFIER: chemistry
QUALIFIER: analysis
AUTHOR: M Liu M
AFFILIATION: China-Japan Friendship Hospital, Beijing.
PUBTYPE: Journal Article
JOURNALTITLE: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases.
COUNTRY: CHINA
TITLE: [Transforming growth factor-alpha in human lung cancer tissue]
PUBDATE: 19900601
12 cases of human lung cancer tissue were analyzed for the presence of transforming growth factor-alpha with RIA. Histologically 9 were squamous cell carcinoma and 3 were adenocarcinoma. Except one squamous carcinoma, TGF-alpha could be detected in 11 cases. TGF-alpha level was from 0.26 ng to 1.26 ng per gram tissue. There was no significant difference in TGF-alpha level between squamous cell carcinoma and adenocarcinoma. The relationship between TGF-alpha and human lung cancer remains for further study.


10. DOCID:20511 SCORE: 0.00341465989667457
DOCNO: 9460335
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: drug therapy
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
AUTHOR: T J Powles TJ
AFFILIATION: Royal Marsden Hospital, Sutton, Surrey.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: European journal of cancer care.
COUNTRY: ENGLAND
TITLE: Evolving clinical strategies: innovative approaches to the use of mitoxantrone--introduction.
PUBDATE: 19971201
New clinical strategies and innovative approaches to the use of mitoxantrone include high-dose treatment, new combinations such as 5-fluorouracil with leucovorin (NFL), and neoadjuvant therapy for metastatic and primary breast cancer. Its use in other malignancies such as acute leukaemia and low-grade non-Hodgkin's lymphoma are also areas of significant development.


11. DOCID:19893 SCORE: 0.00323646862090166
DOCNO: 1551076
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: ultrastructure
QUALIFIER: genetics
QUALIFIER: pathology
AUTHOR: C Sreekantaiah C
AUTHOR: M K Bhargava MK
AFFILIATION: Department of Pathology, Kidwai Memorial Institute of Oncology, Bangalore, India.
PUBTYPE: Journal Article
JOURNALTITLE: Cancer genetics and cytogenetics.
COUNTRY: UNITED STATES
TITLE: Double minute chromatin bodies in carcinoma of the human cervix uteri.
PUBDATE: 19920201
In direct G-banded preparations of 150 cases of cervical cancer, double minutes (dmin) were observed in 43% (64 cancers) of the patients, including a case of carcinoma-in-situ (CIS). The incidence of dmin varied from 1 to over 20 per cell. The karyotypic findings in the tumors containing dmin did not reveal any similarities and the prognosis of the patients with dmin was significantly worse compared to those without dmin. The presence of dmin in cytogenetic preparations of primary tumors may indicate a role in the maintenance and/or progression of malignancy, particularly as dmin have been suggested to represent amplified genes.


12. DOCID:23169 SCORE: 0.0031829421732717
DOCNO: 7501534
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Attitude to Health
QUALIFIER: psychology
QUALIFIER: psychology
QUALIFIER: psychology
QUALIFIER: surgery
AUTHOR: J Watt-Watson J
AUTHOR: J Graydon J
AFFILIATION: Faculty of Nursing, University of Toronto, Ontario, Canada.
PUBTYPE: Journal Article
JOURNALTITLE: The Nursing clinics of North America.
COUNTRY: UNITED STATES
TITLE: Impact of surgery on head and neck cancer patients and their caregivers.
PUBDATE: 19951201
Little information has been gathered about the experiences of head and neck cancer patients at the time of their initial surgery and about the ramifications of the surgery for patients and their caregivers. The authors discuss the pain experience of patients, the relationship of pain to their fatigue and negative mood, and the concerns of both patients and caregivers. Family caregivers are expected to take responsibility for the patients, and it is important for nurses to recognize the concerns of both patients and caregivers at the time of discharge into the home setting.


13. DOCID:16761 SCORE: 0.00311022438461839
DOCNO: 1497830
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Nursing Diagnosis
QUALIFIER: nursing
QUALIFIER: therapy
AUTHOR: T J Aitken TJ
PUBTYPE: Journal Article
JOURNALTITLE: Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses.
COUNTRY: UNITED STATES
TITLE: Gastrointestinal manifestations in the child with cancer.
PUBDATE: 19920701
Pediatric oncology nurses provide a major role in the assessment and management of gastrointestinal complications in children resulting from cancer therapies. The clinical problems most frequently seen in this area include stomatitis, nausea, vomiting, constipation, and diarrhea. These areas are reviewed in detail according to various nursing diagnoses including definitions and pathophysiology, recent studies and interventions, special considerations for children, and patient and parent education.


14. DOCID:22431 SCORE: 0.0030787614776549
DOCNO: 9224590
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: complications
QUALIFIER: etiology
QUALIFIER: surgery
AUTHOR: R J Gimpelson RJ
AFFILIATION: Department of Obstetrics and Gynecology, St. Louis University School of Medicine, St. Louis, Missouri, USA.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of the American Association of Gynecologic Laparoscopists.
COUNTRY: UNITED STATES
TITLE: Not so benign endometrial hyperplasia: endometrial cancer after endometrial ablation.
PUBDATE: 19970801
The masking or development of endometrial cancer after endometrial ablation is a concern often alluded to in discussions of complications of endometrial ablation. It is necessary to look for a common factor when this complication occurs. Six cases published in peer-reviewed literature were collected to establish a link between the development of endometrial cancer and endometrial ablation. Preexisting endometrial hyperplasia seems to be the common denominator, and should be considered a contraindication to endometrial ablation until more data are collected.