0. DOCID:19769 SCORE: 0.00505739905744972
DOCNO: 8483604
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Prostheses and Implants
QUALIFIER: surgery
QUALIFIER: radiotherapy
QUALIFIER: surgery
AUTHOR: G Granström G
AUTHOR: A Tjellström A
AUTHOR: P I Brånemark PI
AUTHOR: J Fornander J
AFFILIATION: Department of Otolaryngology-Head and Neck Surgery, Ostra Hospital, University of Gothenburg, Sweden.
PUBTYPE: Journal Article
JOURNALTITLE: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
COUNTRY: UNITED STATES
TITLE: Bone-anchored reconstruction of the irradiated head and neck cancer patient.
PUBDATE: 19930401
Titanium implants in facial bones for retention of epitheses or dental bridges were used for reconstruction in cancer patients after tumor surgery. Even heavily irradiated bones could integrate the implants and bear the load from the epithesis. No major complications, such as wound infection, fistulation, or osteoradionecrosis, occurred after implant surgery. There was, however, an increased loss of implants with time after irradiation, especially in the orbital region. When hyperbaric oxygen was used as adjunctive treatment, implant losses were reduced.

1. DOCID:18560 SCORE: 0.00460490342165036
DOCNO: 1323751
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: physiopathology
QUALIFIER: physiopathology
QUALIFIER: etiology
QUALIFIER: physiology
AUTHOR: B E Smith BE
AFFILIATION: Mayo Medical School, Scottsdale, Arizona.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Neurologic clinics.
COUNTRY: UNITED STATES
TITLE: Inflammatory sensory polyganglionopathies.
PUBDATE: 19920801
The inflammatory sensory polyganglionopathies are a group of uncommon neurologic disorders primarily affecting dorsal root ganglion cells and their processes. Subdivided into malignant and nonmalignant inflammatory sensory polyganglionopathy, these conditions are important in the differential diagnosis of sensory neuropathy. The clinical significance of malignant inflammatory sensory polyganglionopathy, a paraneoplastic syndrome, rests in the discovery of subclinical cancer, which may produce antineuronal nuclear antibodies directed against the dorsal root ganglion cell and other neurons resulting in characteristic neurologic deficits. Prompt recognition of these distinctive signs and symptoms may result in early diagnosis and improved patient survival and lead to a better understanding of immune-mediated neurologic disease.

2. DOCID:19528 SCORE: 0.00384528692082569
DOCNO: 2164207
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnostic use
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: analysis
AUTHOR: J Guzman J
AUTHOR: A Kraft A
AUTHOR: K J Bross KJ
AUTHOR: G Würtemberger G
AUTHOR: U Costabel U
AFFILIATION: Pathologisches Institut und Medizinische Klinik der Universität Freiburg.
PUBTYPE: Journal Article
JOURNALTITLE: Pneumologie (Stuttgart, Germany)
COUNTRY: GERMANY, WEST
TITLE: [Immunocytochemical characterization of malignant pleural effusions of small cell bronchial cancer]
PUBDATE: 19900201
In pleural effusions, histologically proven to be malignant in 13 patients with small cell lung cancer, the immunocytological profile of tumour cells, together with the distribution of the lymphocyte subpopulations, were established. In all cases, tumor cells were demonstrable with the monoclonal antibodies EMA, HEA-125, Sam 2, 6, 8 and 10. In contrast, conventional cytology was positive in only 6 of the 13 cases. As in other malignant or inflammatory effusions, phenotyping of the lymphocytes revealed an elevated T4/T8 ratio in comparison with the normal value for peripheral blood.

3. DOCID:19735 SCORE: 0.00377221398889351
DOCNO: 1955228
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: complications
QUALIFIER: etiology
AUTHOR: K Yoshioka K
AUTHOR: T Kono T
AUTHOR: J Kitajima J
AUTHOR: K Nakagawa K
AUTHOR: N Yashiro N
AUTHOR: S Taniguchi S
AUTHOR: M Furukawa M
AUTHOR: T Hamada T
AFFILIATION: Department of Dermatology, Osaka City University Medical School, Japan.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: International journal of dermatology.
COUNTRY: UNITED STATES
TITLE: Squamous cell carcinoma developing in epidermolysis bullosa dystrophica.
PUBDATE: 19911001
Two patients with epidermolysis bullosa dystrophica recessiva who had squamous cell carcinoma are presented. Case 1 is a 40-year-old woman who had ulcers on her left lower leg. Case 2 is a 42-year-old man who had a tumor on his left first toe. Wide surgical excision with skin coverage by autograft was performed in case 1. Amputation of the toe in case 2 was performed. A review of the cases of epidermolysis bullosa dystrophica associated with cancer reported in Japan is also presented.

4. DOCID:19648 SCORE: 0.00377219955641381
DOCNO: 8204923
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: genetics
QUALIFIER: genetics
QUALIFIER: genetics
AUTHOR: P Lalle P
AUTHOR: D Stoppa-Lyonnet D
AUTHOR: S Mazoyer S
AUTHOR: P Rio P
AUTHOR: C Girodet C
AUTHOR: A Hardouin A
AUTHOR: S A Narod SA
AUTHOR: H Sobol H
AUTHOR: Y J Bignon YJ
AFFILIATION: Laboratoire d'oncologie moléculaire, centre Jean-Perrin, Clermont-Ferrand, France.
PUBTYPE: Journal Article
JOURNALTITLE: Bulletin du cancer.
COUNTRY: FRANCE
TITLE: [Hereditary predisposition for cancer of the breast and the ovary]
PUBDATE: 19931001
Familial breast cancers represent about 10% of all cases of breast cancers. A predisposition locus has been located in the 17q21 chromosomal region. Nineteen French breast and breast-ovarian cancer families were tested for linkage with five highly polymorphic 17q markers. The five breast-ovarian cancer families as a group give positive evidence for linkage, whereas the 14 breast cancer families do not. Heterogeneity of linkage of familial breast cancer is significant in France and supports the existence of more than one susceptibility gene.

5. DOCID:18891 SCORE: 0.00372810063443648
DOCNO: 1888656
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Mammography
QUALIFIER: radiography
QUALIFIER: radiography
AUTHOR: Y Grumbach Y
AUTHOR: H T Nguyen HT
AFFILIATION: Amiens University Medical Center, France.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Current opinion in radiology.
COUNTRY: UNITED STATES
TITLE: Mammography in younger women.
PUBDATE: 19910801
Breast imaging is not frequently performed in women aged 35 years or younger for several reasons. Approximately half of the radiographic examinations of a breast symptom give normal results because the expected density of the breast in younger women may obscure abnormalities. Results from biopsies performed subsequent to positive mammogram findings confirm the predominance of benign lesions; cancers are rarely observed. After reviewing the main breast diseases that occur in the 20- to 35-year-old age group, we evaluated the accuracy of mammography in diagnosing malignancy, and attempted to summarize guidelines for breast imaging in young women, whose breasts are quite sensitive to radiation.

6. DOCID:16604 SCORE: 0.00362917856291494
DOCNO: 2213910
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Electromagnetic Fields
DESCRIPTOR: Occupational Exposure
QUALIFIER: instrumentation
AUTHOR: A Trappier A
AUTHOR: P Lorio P
AUTHOR: L P Johnson LP
AFFILIATION: Bio-Magnetics Systems, Inc., Newark, NJ 07102.
PUBTYPE: Journal Article
JOURNALTITLE: Journal of the National Medical Association.
COUNTRY: UNITED STATES
TITLE: Evolving perspectives on the exposure risks from magnetic fields.
PUBDATE: 19900901
Based on information from suggesting effects of positive and negative polarity on cancer cells, surveys were performed on magnetic resonance imaging devices, as well as other types of equipment capable of producing appreciable magnetic fields. These surveys were performed in areas where there was a potential for both occupational and general public exposure.

7. DOCID:18440 SCORE: 0.00341383884687323
DOCNO: 1850333
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Liver Neoplasms
QUALIFIER: secondary
QUALIFIER: secondary
QUALIFIER: etiology
QUALIFIER: blood
AUTHOR: S Otabe S
AUTHOR: S Muto S
AUTHOR: Y Asano Y
AUTHOR: K Sato K
AUTHOR: M Ohtani M
AUTHOR: C Kawamoto C
AUTHOR: K Ido K
AUTHOR: K Kimura K
AFFILIATION: Department of Gastroenterology, Jichi Medical School, Tochigi, Japan.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Clinical nephrology.
COUNTRY: GERMANY
TITLE: Hyperreninemic hypoaldosteronism due to hepatocellular carcinoma metastatic to the adrenal gland.
PUBDATE: 19910201
Metastases to the adrenal glands are common in patients with cancer, but among those affected, hyperreninemic hypoaldosteronism is noted very rarely. A case of hyperreninemic hypoaldosteronism secondary to metastatic hepatocellular carcinoma is reported. Laboratory data revealed selective aldosterone deficiency with hyperreninemia. Biopsy documented replacement of the adrenal glands with metastatic hepatocellular carcinoma. A review of the literature disclosed that the present case was an extremely rare one of its kind.

8. DOCID:16404 SCORE: 0.00314561318477496
DOCNO: 1918190
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Genome, Human
QUALIFIER: genetics
AUTHOR: W F Bodmer WF
AFFILIATION: Imperial Cancer Research Fund, London.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Hospital practice (Office ed.)
COUNTRY: UNITED STATES
TITLE: Cancer genetics and the human genome.
PUBDATE: 19911001
We can fully expect that the information from the genome project, combined with epidemiologic and other genetic studies, will pinpoint the series of events, in germ cells and somatic cells, that result in the initiation and progression of the various cancers. Within 10 years, the treatment and prevention of at least one of the major common cancers should be within reach.

9. DOCID:18849 SCORE: 0.00312206051379532
DOCNO: 8294236
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: isolation & purification
QUALIFIER: pharmacology
QUALIFIER: metabolism
AUTHOR: K Kojiri K
AUTHOR: S Nakajima S
AUTHOR: H Suzuki H
AUTHOR: A Okura A
AUTHOR: H Suda H
AFFILIATION: New Drug Discovery Research Laboratories, Tsukuba Research Institute, Banyu Pharmaceutical Co., Ltd., Japan.
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of antibiotics.
COUNTRY: JAPAN
TITLE: A new antitumor substance, BE-18591, produced by a streptomycete. I. Fermentation, isolation, physico-chemical and biological properties.
PUBDATE: 19931201
New antitumor substance, designated BE-18591, was isolated from the culture broth of a streptomycete, strain BA18591. The active principle was extracted from mycelium by methanol and purified by silica gel chromatography. BE-18591 inhibited the growth of MKN-45 human stomach cancer cell line as well as P388 cell line. In in vivo experiments, BE-18591 inhibited the growth of Ehrlich ascites tumor.BE-18591 showed antimicrobial activity against Gram-positive and some Gram-negative bacteria.

10. DOCID:17034 SCORE: 0.00307372708816034
DOCNO: 8255582
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: drug therapy
QUALIFIER: pharmacology
AUTHOR: M P Kalapos MP
AFFILIATION: Boston Biomedical Research Institute, Department of Metabolic Regulation.
PUBTYPE: Biography
PUBTYPE: Historical Article
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Orvosi hetilap.
COUNTRY: HUNGARY
TITLE: [Submolecular theory of cancer. In memoriam Albert Szent-Györgyi]
PUBDATE: 19931201
The author surveys the way leading to the electronic theory of cancer and analyses the role of methylglyoxal and glyoxalases. Based on the comparison of experimental data with the theory it can be concluded that (i) data being at disposal are not convincing enough either to verify or to confute the theory; (ii) compounds having function to influence the glyoxalase system can, however, be considered as tumour-selective anticancer agents.

11. DOCID:18411 SCORE: 0.00302653483567999
DOCNO: 1423237
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Diploidy
QUALIFIER: genetics
QUALIFIER: genetics
AUTHOR: M Johansson M
AUTHOR: Y Jin Y
AUTHOR: S Heim S
AUTHOR: N Mandahl N
AUTHOR: G Hambraeus G
AUTHOR: L Johansson L
AUTHOR: F Mitelman F
AFFILIATION: Department of Clinical Genetics, University Hospital, Lund, Sweden.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Cancer genetics and cytogenetics.
COUNTRY: UNITED STATES
TITLE: Pseudodiploid karyotypes in adenosquamous carcinomas of the lung.
PUBDATE: 19921001
Pseudodiploid karyotypes with clonal structural rearrangements were observed in short-term cultures from two adenosquamous carcinomas (ASC) of the lung, a tumor type hitherto virtually uncharacterized cytogenetically. The karyotypes were 46,XX,der(1)t(1;14)(q44;q22),add(9)(q34) in the first tumor and 46,XX,i(17)(q10) in the second tumor. We suggest that ASC of the lung differ from other lung cancers by having pseudodiploid instead of massively aneuploid tumor stemlines.

12. DOCID:17695 SCORE: 0.00302042278771862
DOCNO: 8409699
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Receptors, Cell Surface
AUTHOR: C W Distelhorst CW
AFFILIATION: Department of Medicine, Case Western Reserve University, Cleveland, Ohio 44106-4937.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The Journal of laboratory and clinical medicine.
COUNTRY: UNITED STATES
TITLE: Steroid hormone receptors.
PUBDATE: 19930901
Tremendous advances have been made in understanding the fundamental mechanisms of steroid hormone action. The cloning of the genes that encode classic steroid hormone receptors revealed that these receptors are but part of a large family of ligand-responsive transcriptional regulators. This fundamental advance has already contributed greatly to our understanding of a variety of diseases, particularly cancer, and the total dividend has not yet been realized. Steroid receptors have been and will be a fruitful area of research for many years.

13. DOCID:19738 SCORE: 0.00300855484410235
DOCNO: 1626943
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Gastrectomy
QUALIFIER: administration & dosage
QUALIFIER: secondary
QUALIFIER: drug therapy
AUTHOR: T Mura T
AUTHOR: H Bandou H
AUTHOR: T Nomura T
AUTHOR: K Watanabe K
AUTHOR: T Kobayashi T
AFFILIATION: Department of Surgery, NTT Kanazawa Hospital, Ishikawa, Japan.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [A resected case of advanced gastric cancer with complete remission of liver metastasis by chronic daily administration of oral etoposide and UFT]
PUBDATE: 19920701
An advanced gastric cancer with liver metastasis was treated with the combination MMC, Etoposide and UFT. Etoposide was administered orally at 25-50 mg/day to the gastric cancer patient with liver metastasis. In operative findings, there was no liver and lymphoid node metastasis. The gastric tumor diminished in size and changed its characteristics due to the chemotherapy. In 19 months, no liver nor LN metastasis was observed by CT scan. Presently, the patient feels well and receives outpatient treatment.

14. DOCID:19680 SCORE: 0.00300855292697218
DOCNO: 1626943
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Gastrectomy
QUALIFIER: administration & dosage
QUALIFIER: secondary
QUALIFIER: drug therapy
AUTHOR: T Mura T
AUTHOR: H Bandou H
AUTHOR: T Nomura T
AUTHOR: K Watanabe K
AUTHOR: T Kobayashi T
AFFILIATION: Department of Surgery, NTT Kanazawa Hospital, Ishikawa, Japan.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [A resected case of advanced gastric cancer with complete remission of liver metastasis by chronic daily administration of oral etoposide and UFT]
PUBDATE: 19920701
An advanced gastric cancer with liver metastasis was treated with the combination MMC, Etoposide and UFT. Etoposide was administered orally at 25-50 mg/day to the gastric cancer patient with liver metastasis. In operative findings, there was no liver and lymphoid node metastasis. The gastric tumor diminished in size and changed its characteristics due to the chemotherapy. In 19 months, no liver nor LN metastasis was observed by CT scan. Presently, the patient feels well and receives outpatient treatment.