0. DOCID:11399 SCORE: 0.00596287455029616
DOCNO: 6857203
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Occult Blood
QUALIFIER: diagnosis
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: R Gnauck R
PUBTYPE: Journal Article
JOURNALTITLE: Schweizerische medizinische Wochenschrift.
COUNTRY: SWITZERLAND
TITLE: [Practical experiences with the stool test for occult blood]
PUBDATE: 19830401
In the light of the literature and 10 years personal experience, the following conclusions are drawn: 1. Screening for colon cancer with Hemoccult works and is practicable. 2. Asymptomatic and unknown symptomatic cancers are detected. 3. These cancers are predominantly in an early stage (70% at Dukes A and B). 4. Large adenomatous polyps, i.e. precancerous neoplasias, can also be detected. 5. One-time testing may miss 15-20% of cancers and 40-50% of adenomatous polyps (depending on their size!). 6. Repeated screening during the 2 years before diagnosis lowers these false-negative figures to less than 10% in carcinomas and less than 30% in large polyps. 7. Screening for colon cancer should be started at age 45 and thereafter repeated annually.


1. DOCID:15260 SCORE: 0.00557555480784048
DOCNO: 2740581
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: I De Llano Rodríguez I
AUTHOR: L Rodrigo Sáez L
AUTHOR: D Prados Cano D
AUTHOR: H Schleiman Halabi H
PUBTYPE: Journal Article
JOURNALTITLE: Revista española de las enfermedades del aparato digestivo.
COUNTRY: SPAIN
TITLE: [Groups at risk and early detection of cancer of the colon and rectum]
PUBDATE: 19890401
Early detection of cancer of the colon and rectum is fundamental because survival is linked to the pathologic stage. The population groups at high risk are reviewed, as well as the different screening techniques: search for occult blood in stool (Hemoccult), rectal palpation, rigid rectosigmoidoscopy, flexible fiberoptic sigmoidoscopy, radiology and determination of carcinoembryonic antigen. It is concluded that the Hemoccult test is the most useful technique for early diagnosis and it should be performed in individuals over 40 years and in the high risk population. The other diagnostic tests should be carried out if this test is positive.


2. DOCID:14609 SCORE: 0.00557551730196334
DOCNO: 2691730
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: R Yatani R
AUTHOR: I Kusano I
AUTHOR: T Shiraishi T
AUTHOR: T Hayashi T
AUTHOR: G N Stemmermann GN
AFFILIATION: Department of Pathology, Mie University School of Medicine.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Japanese journal of clinical oncology.
COUNTRY: JAPAN
TITLE: Latent prostatic carcinoma: pathological and epidemiological aspects.
PUBDATE: 19891201
In conclusion, a review of the epidemiology and pathology of latent prostatic cancer suggests this tumor to be the probable initial phase of a biological continuum that ends with metastatic cancer. Histological grade and tumor volume are highly correlated, as are histological grade and mitotic index. It has also been suggested that atypical intraductal hyperplasia is, in turn, a precursor of carcinoma. This concept gains support from the close association of the two conditions among younger (less than 60 years of age) patients and from their similar mitotic and labeling indices.


3. DOCID:10565 SCORE: 0.00492724347669841
DOCNO: 6313983
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: M Fukuoka M
AUTHOR: M Takada M
AUTHOR: S Negoro S
AUTHOR: S Tamai S
AUTHOR: K Matsui K
AUTHOR: N Sakai N
AUTHOR: S Ryu S
AUTHOR: T Yoshinaga T
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [Conditions suitable for chemotherapy of lung cancer]
PUBDATE: 19830801
The influence of several factors for response to Chemotherapy and survival was analysed in 310 patients with inoperable lung cancer who were treated by single or combination chemotherapy. In small cell lung cancer, survival was strongly affected by the results of induction chemotherapy, and combination chemotherapy with three or four drugs was most effective. In non-small cell lung cancer, performance status and body weight loss on admission were important factors for response to chemotherapy and survival. Combinations did not improve the response rate in non-small cell lung cancer.


4. DOCID:10950 SCORE: 0.00447161928946932
DOCNO: 6696687
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: epidemiology
QUALIFIER: epidemiology
AUTHOR: H Goepfert H
AUTHOR: W J Dichtel WJ
AUTHOR: N A Samaan NA
PUBTYPE: Journal Article
JOURNALTITLE: Archives of otolaryngology (Chicago, Ill. : 1960)
COUNTRY: UNITED STATES
TITLE: Thyroid cancer in children and teenagers.
PUBDATE: 19840201
A study of thyroid cancer in patients younger than 20 years showed most tumors to be of the differentiated type. Histological types were pure papillary adenocarcinoma (9.5%), mixed papillary and follicular adenocarcinoma (77%), pure follicular adenocarcinoma (2.7%), and medullary carcinoma (10.8%). Of the patients with differentiated carcinoma, 84% had palpable cervical lymphadenopathy and 11% had pulmonary metastasis on admission. Patients with differentiated carcinoma were followed up for a mean of 15.4 years, and patients with medullary carcinoma for a mean of 7.3 years. No patient died as a result of papillary or follicular carcinoma, but two (25%) died of medullary carcinoma. Permanent hypoparathyroidism was found in 17% of patients after total thyroidectomy.


5. DOCID:10970 SCORE: 0.00431905276487843
DOCNO: 6337854
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analysis
QUALIFIER: analysis
QUALIFIER: immunology
QUALIFIER: analysis
QUALIFIER: immunology
AUTHOR: A S Daar AS
AUTHOR: J W Fabre JW
PUBTYPE: Journal Article
JOURNALTITLE: European journal of cancer & clinical oncology.
COUNTRY: ENGLAND
TITLE: The membrane antigens of human colorectal cancer cells: demonstration with monoclonal antibodies of heterogeneity within and between tumours and of anomalous expression of HLA-DR.
PUBDATE: 19830201
The membrane antigens of fifteen colorectal tumours were studied using a number of monoclonal antibodies and the immunoperoxidase technique on frozen sections. With this approach we could easily demonstrate differences in the membrane structure of the cancer cells within the tumour mass of given patients and also readily demonstrate differences between tumours that were indistinguishable by histological and other standard criteria. An unexpected finding was the patchy expression of HLA-DR antigens on cancer cells, in spite of the absence of HLA-DR on normal colorectal epithelium. These findings have interesting theoretical and clinical implications.


6. DOCID:11757 SCORE: 0.00379320430579567
DOCNO: 6092890
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: U Yonemura U
AUTHOR: K Konishi K
AUTHOR: I Miazaki I
AUTHOR: K Miwa K
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Nippon Geka Gakkai zasshi.
COUNTRY: JAPAN
TITLE: [Morphological and immunocytochemical studies of pancreatic multiple endocrine neoplasia type-1]
PUBDATE: 19840801
Morphological and immunocytochemical studies of pancreatic material from a patient with multiple endocrine neoplasia type-1 revealed hyperplasia of islets, multiple microadenomas, adenomas and cancers. Cellular composition of the hyperplastic islets was almost normal but the enlargement of the size and increase of the numbers were observed. Furthermore, neoformation of islets from ducts were found here and there. These hyperplastic islets, microadenomas, adenomas and cancers merged into each other and some of these microadenomas demonstrated malignant pictures. Most of the microadenomas produced multiple peptide hormones, on the other hand some of these revealed a single hormonal activity. These results show that the abnormality of the primordial cells of the pancreatic endocrine cells develops these lesion.


7. DOCID:9798 SCORE: 0.00373972493516705
DOCNO: 3004726
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
QUALIFIER: therapeutic use
AUTHOR: T P Miller TP
AUTHOR: R B Livingston RB
PUBTYPE: Journal Article
JOURNALTITLE: Cancer treatment reports.
COUNTRY: UNITED STATES
TITLE: Phase II trial of 5-FU, vincristine, and mitomycin (FOMi) in metastatic bronchioloalveolar cell lung cancer: a Southwest Oncology Group Study.
PUBDATE: 19851101
Twenty-three previously untreated patients with bronchioloalveolar cell lung cancer who had measurable disease and distant metastases (stage IIIM1, extensive) were treated with combination chemotherapy including 5-FU, vincristine, and mitomycin. Two of 23 patients (9%) achieved partial response lasting 5 and 6 months. Two patients (9%) died of sepsis while neutropenic. The current study does not justify the use of 5-FU, vincristine, and mitomycin combination chemotherapy in patients with metastatic bronchioloalveolar cell lung cancer.


8. DOCID:15987 SCORE: 0.00369582630707352
DOCNO: 3764396
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiography
QUALIFIER: radiography
AUTHOR: M Schamaun M
AUTHOR: A Rüttimann A
PUBTYPE: Journal Article
JOURNALTITLE: Schweizerische medizinische Wochenschrift.
COUNTRY: SWITZERLAND
TITLE: [Cavernous bronchus carcinoma]
PUBDATE: 19860901
In thoracic surgery patients the etiology of cavities has drastically changed in the last 20 years. While at present only very few patients need surgery for cavernous tuberculosis, cavities of cancerous origin are becoming more and more frequent. During the period from 1977 to 1985 24 out of 225 bronchogenic carcinomas treated by resection were found to be cavernous (10.7%). Radiologically the degree of cavitation extended from a small marginal or central air collection to the formation of large, irregular, and thick-walled caverns. The excavation is the result of necrobiotic changes within the tumor. It arises when the tumor masses penetrate into the bronchial tree and are expectorated. However, prognosis of cavitated cancer remains exclusively dependent on the stage of the tumor. The cavitation itself seems not to influence it.


9. DOCID:9188 SCORE: 0.00364544806886123
DOCNO: 6547214
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: secondary
QUALIFIER: secondary
AUTHOR: A Mauro A
PUBTYPE: Journal Article
JOURNALTITLE: Minerva medica.
COUNTRY: ITALY
TITLE: [Leptomeningeal carcinomatous metastases]
PUBDATE: 19840501
The metastatic involvement of leptomeninges is an uncommon complication of systemic cancer, but there are evidences that its incidence is increasing, particularly for breast cancer. The two commonest primary sites are the breast and the lung and adenocarcinoma is the most frequent histologic type of carcinoma to metastasize to the leptomeninges. Clinical diagnosis is suggested by the simultaneous occurrence of symptoms and signs in more than one areas of CNS. Examination of cerebrospinal fluid is the most helpful diagnostic procedure. A combination of radiotherapy and intrathecal or intraventricular administration of Methotrexate seems to be the most successful treatment.


10. DOCID:11388 SCORE: 0.00355048216898976
DOCNO: 6652592
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: standards
QUALIFIER: epidemiology
AUTHOR: E A Clarke EA
AUTHOR: S Hilditch S
PUBTYPE: Journal Article
JOURNALTITLE: Canadian Medical Association journal.
COUNTRY: CANADA
TITLE: Problems in determining the incidence of cervical cancer.
PUBDATE: 19831201
Since cancer registries have different recording practices, the incidence rates that they report must be compared with caution. Indexes of reliability of recording indicated that in 1971 the reported incidence of cervical cancer in Ontario was too high. In 1971 Ontario used a method of passive reporting of cancer cases: the Ontario Cancer Registry linked hospital reports, death certificates and reports from the Ontario Cancer Treatment and Research Foundation's treatment centres to produce a single record for each case. Pathological confirmation was requested for cases thus recorded by the registry. In 26% of cases a diagnosis other than cervical cancer was indicated. With these cases omitted, the incidence rate became 15.1/100 000, as opposed to the 20.5/100 000 reported by the registry.


11. DOCID:14364 SCORE: 0.0035290241352467
DOCNO: 3050199
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
AUTHOR: T Okawa T
AUTHOR: K Yamada K
AUTHOR: M Kita M
AFFILIATION: Dept. of Radiology, Tokyo Women's Medical College.
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [Early cancer in the head and neck]
PUBDATE: 19880801
In head and neck tumors, there is no definition of early cancer. If T1N0M0, no lymph node and distant metastasis, will be early cancer, it is difficult to detect the tumor at early phase in head and neck tumor except for tongue and laryngeal cancer. Because it is hard to define it at early stage in the tumor surrounding by bony structure or tumor growing endophytically. Although almost tumor of head and neck were easily diagnosed by inspection and palpation, total imaging examination should be done actively for detection of early stage of cancer.


12. DOCID:14395 SCORE: 0.00350361243447139
DOCNO: 3464227
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: complications
AUTHOR: T Fujimoto T
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [Antibiotic therapy of acute infection in patients with cancer]
PUBDATE: 19861001
Considerable progress has been made in the supportive care of patients undergoing cancer therapy. This progress has been associated with the improved survival of some patients. However, infection continues to be the major fatal complication in cancer. patients. The response of granulocytopenic patients with infections to some of the current available antibiotics is suboptimal. Since neutropenia is common during cancer treatment, there is a continual risk of infection in cancer patients; thus it is important for medical oncologists to become aware of these complications and their management. The most frequent types of acute infections, their clinical manifestations, and available antibiotic therapies were reviewed.


13. DOCID:14939 SCORE: 0.00346311209347444
DOCNO: 3629853
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Hemostasis
QUALIFIER: physiology
QUALIFIER: blood
AUTHOR: A N Tulupov AN
AUTHOR: V I Buravtsov VI
AUTHOR: A L Kostiuchenko AL
AUTHOR: S V Grishakov SV
AUTHOR: A N Bel'skikh AN
PUBTYPE: Journal Article
JOURNALTITLE: Vestnik khirurgii imeni I. I. Grekova.
COUNTRY: USSR
TITLE: [Clinical importance of changes in thrombocytic hemostasis in lung cancer]
PUBDATE: 19870401
Clinico-laboratory examinations of 86 patients have shown that lung cancer develops against the background of activation of the thrombocytic link of hemostasis which manifested itself in thrombocytosis, greater degree of destruction of the lysosomal membranes, lower energy resources of the cells, their tendency to slow and little reversible aggregation. The authors consider that the indicators of the ADP-induced aggregation of thrombocytes may be used for prognosis of postoperative pyo-inflammatory and thromboembolic complications. HBO is good for correction of alterations in the thrombocytic link of hemostasis in lung cancer and its suppurative complications.


14. DOCID:10061 SCORE: 0.00341518103528335
DOCNO: 6851804
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analysis
QUALIFIER: blood
AUTHOR: A J Krush AJ
AUTHOR: N Zamcheck N
AUTHOR: H T Lynch HT
PUBTYPE: Journal Article
JOURNALTITLE: Diseases of the colon and rectum.
COUNTRY: UNITED STATES
TITLE: CEA and genetics. Gardner's syndrome.
PUBDATE: 19830601
During an eight-year period, serial plasma determinations were made on members of a Gardner's syndrome family in order to see if 1. levels rise when polyps first appear, and when cancer occurs; and 2. levels fall after colectomy with ileoproctostomy, ileostomy, or rectal mucosal replacement surgery. CEA analyses were carried out in the laboratory of Norman Zamcheck, M.D., using the Roche method. Small increases in CEA titer accompanied the appearance of polyps and small decreases accompanied their removal. Further serial studies are needed to determine whether changes in CEA titer can be indicators of polyp and/or cancer occurrence.