0. DOCID:25581 SCORE: 0.00236567493147002
DOCNO: 11577673
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
QUALIFIER: prevention & control
QUALIFIER: prevention & control
AUTHOR: B F Barker BF
AUTHOR: G J Barker GJ
AFFILIATION: Department of Oral and Maxillofacial Pathology, University of Missouri-Kansas City School of Dentistry, USA. barkerb@umkc.edu
PUBTYPE: Journal Article
JOURNALTITLE: Journal of the California Dental Association.
COUNTRY: United States
TITLE: Oral management of the patient with cancer in the head and neck region.
PUBDATE: 20010801
Cancer therapies--including surgery, radiation, and chemotherapy--may unfavorably affect the oral/dental health of patients. Existing dental problems can also result in serious complications that may be prevented by dental intervention prior to cancer therapy. This paper will be limited to a discussion of the detrimental effects of radiation therapy on the oral cavity and salivary glands and appropriate dental management.


1. DOCID:26461 SCORE: 0.00207746634095906
DOCNO: 12013537
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
AUTHOR: G W Sledge GW
AFFILIATION: Indiana University School of Medicine, Indianapolis, USA. gsledge@iupui.edu
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Journal of mammary gland biology and neoplasia.
COUNTRY: United States
TITLE: Breast cancer in the clinic: treatments past, treatments future.
PUBDATE: 20011001
Therapeutic options for the patient with systemic breast cancer were long limited to either chemotherapy and hormonal therapy. While these therapies provide palliation for many patients with advanced disease, and occasionally cure the patient with micrometastatic disease, they are not optimal either with regard to toxicity or efficacy. This paper reviews the past of systemic therapy (chemotherapy and hormonal therapy), then discusses developing treatment strategies. These strategies include the recently introduced anti-HER-2 antibody trastuzumab, novel agents targeting other aspects of tumor growth mechanisms, as well as agents blocking angiogenesis.


2. DOCID:27513 SCORE: 0.00182801215060964
DOCNO: 9528237
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: transplantation
QUALIFIER: surgery
AUTHOR: T Kaneko T
AUTHOR: S Uemura S
AUTHOR: H Harada H
AUTHOR: S Sugihara S
AUTHOR: T Egami T
AFFILIATION: Department of Surgery, Shimonoseki Kousei Hospital, Yamaguchi, Japan.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Kyobu geka. The Japanese journal of thoracic surgery.
COUNTRY: JAPAN
TITLE: [A case of acute empyema who underwent omentopexy and was found to have gastric cancer during operation]
PUBDATE: 19980301
A 76-year-old man had undergone omentopexy for empyema. He was found to have gastric cancer and revealed Borrmann III by gastroendoscopy intraoperative period. Segmental gastrectomy was performed without dissection of lymph nodes, because his general condition was poor. After operation, the patient showed septic shock, ARDS and hepato-renal failure but his condition was getting improved by conservative therapy. After 5 years later, he was examined gastro-endoscopy, abdominal and chest CT and revealed no recurrence sign.


3. DOCID:26993 SCORE: 0.00155919843254587
DOCNO: 9646040
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Models, Genetic
QUALIFIER: genetics
QUALIFIER: genetics
AUTHOR: K Shannon K
AFFILIATION: Department of Pediatrics, University of California, San Francisco 94143, USA. kevins@itsa.ucsf.edu
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Environmental health perspectives.
COUNTRY: UNITED STATES
TITLE: Genetic predispositions and childhood cancer.
PUBDATE: 19980601
This article provides an overview of the problem of genetic susceptibility to childhood cancer with a particular emphasis on problems with ascertaining inherited cancer risk and the role of tumor-suppressor gene mutations in cancer predispositions. The association between neurofibromatosis type 1 and childhood leukemia is used to illustrate some of the issues faced by molecular biologists and genetic epidemiologists in identifying and analyzing at-risk individuals. The problem of incomplete penetrance in cancer susceptibility is presented and potential models are discussed. The article concludes with a number of tentative conclusions from existing data and speculations for future studies.


4. DOCID:27001 SCORE: 0.00155919843251899
DOCNO: 10410154
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Protein Biosynthesis
QUALIFIER: complications
QUALIFIER: therapeutic use
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: etiology
QUALIFIER: complications
AUTHOR: H Koshida H
AUTHOR: T Kametani T
AUTHOR: S Masuda S
AFFILIATION: Second Dept. of Internal Medicine, Kohseiren Takaoka Hospital.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [A case of lung cancer with hypercalcemia and renal failure responsive to pamidronate]
PUBDATE: 19990501
A 46-year-old man was diagnosed as Stage IV lung cancer with neck lymph node and bilateral adrenal metastases. He was treated with seven courses of combined chemotherapy (CDDP + etoposide), until he showed extreme hypercalcemia and acute renal failure. The bisphosphonate, pamidronate with elcatonin and prednisolone dramatically lowered his serum calcium level and normalized his renal function. This is a representative case of humoral hypercalcemia of malignancy whose serum calcium could be safely and effectively controlled with pamidronate.


5. DOCID:26111 SCORE: 0.00155918534492885
DOCNO: 10683074
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: D J Booser DJ
AUTHOR: R S Walters RS
AUTHOR: F A Holmes FA
AUTHOR: G N Hortobagyi GN
AFFILIATION: Department of Breast Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston 77030, USA.
PUBTYPE: Clinical Trial
PUBTYPE: Clinical Trial, Phase II
PUBTYPE: Journal Article
JOURNALTITLE: American journal of clinical oncology.
COUNTRY: UNITED STATES
TITLE: Continuous-infusion high-dose leucovorin with 5-fluorouracil and cisplatin for relapsed metastatic breast cancer: a phase II study.
PUBDATE: 20000201
Twelve women with metastatic breast cancer were treated with continuous infusion high dose leucovorin, 5-fluorouracil and cisplatin. Toxicity was severe although the dose was lower than previously described for the treatment of other cancers, and there was little anti-tumor activity. Many other regimens are more effective and less toxic.


6. DOCID:26027 SCORE: 0.00155918534484821
DOCNO: 11579535
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiography
QUALIFIER: secondary
QUALIFIER: radiography
QUALIFIER: secondary
QUALIFIER: radiography
AUTHOR: K Ohno K
AUTHOR: Y Sasaki Y
AFFILIATION: Department of Surgery, Osaka Kosei-Nenkin Hospital, 4-2-78 Fukushima, Fukushima-ku, Osaka, 553-0003, Japan.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society.
COUNTRY: Japan
TITLE: [A case of mediastinal adenocarcinoma of unknown origin presenting as a diffuse tumor shadow in the middle mediastinum]
PUBDATE: 20010701
We report a case of mediastinal adenocarcinoma of unknown origin presenting as a diffuse tumor shadow in the middle mediastinum. Cases of metastasis from cancer of unknown origin to hilar or mediastinal lymph nodes have often been reported. However, our case shows no round shadow indicating an enlarged lymph node, suggesting that the mediastinal adenocarcinoma originated from mediastinal tissue.


7. DOCID:27470 SCORE: 0.00155915859707159
DOCNO: 10757846
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: methods
AUTHOR: J A Ibarra JA
AFFILIATION: Department of Breast Pathology and Cytopathology, MemorialCare Breast Center, Long Beach Memorial Medical Center, Long Beach, California, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Surgical oncology clinics of North America.
COUNTRY: UNITED STATES
TITLE: The pathologist in breast cancer: contemporary issues in the interdisciplinary approach.
PUBDATE: 20000401
The pathologist's contribution to the interdisciplinary team approach in breast cancer management is a cornerstone for decision-making. Continuous communication with the radiologist, surgeon, oncologist, and radiation oncologist is essential. Preoperative diagnosis, surgical specimen work-up with size determination, sentinel lymph node examination, processing forms to facilitate the work-up, and diagnostic templates are some of the items covered in this review of the pathologist's contribution to the interdisciplinary team in breast cancer. Use of diagnostic templates or synoptic reports routinely provide the complete diagnostic information required for treatment decisions.


8. DOCID:24433 SCORE: 0.00154360983677706
DOCNO: 11007245
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Endosonography
QUALIFIER: secondary
QUALIFIER: methods
QUALIFIER: secondary
QUALIFIER: pathology
AUTHOR: T A Woodward TA
AUTHOR: D M Menke DM
AUTHOR: S J Buskirk SJ
AFFILIATION: Division of Gastroenterology, Mayo Clinic Jacksonville, Florida 32224, USA.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: The American journal of gastroenterology.
COUNTRY: UNITED STATES
TITLE: Solitary pelvic nodule: diagnosis of metastatic prostate cancer by endoscopic ultrasound-guided, fine-needle aspiration.
PUBDATE: 20000901
Prostate cancer manifesting as an isolated perirectal mass is a rare occurrence. The following is a report of a single pelvic nodule that was determined to be metastatic prostate cancer by endoscopic ultrasound-guided, fine-needle aspiration.


9. DOCID:24444 SCORE: 0.00154360981951852
DOCNO: 9545192
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Phosphoric Monoester Hydrolases
DESCRIPTOR: Tumor Suppressor Proteins
QUALIFIER: etiology
QUALIFIER: metabolism
AUTHOR: A Smith A
AUTHOR: A Ashworth A
AFFILIATION: Cancer Research Campaign Centre for Cell and Molecular Biology, Section of Gene Function and Regulation, Chester Beatty Laboratories, The Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK. anna@icr.ac.uk
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Current biology : CB.
COUNTRY: ENGLAND
TITLE: Cancer predisposition: where's the phosphate?
PUBDATE: 19980301
Mutations in a protein phosphatase and a protein kinase cause hamartomatous polyposis syndromes, which are characterised by the formation of multiple benign polyps and an increased susceptibility to some types of cancer.


10. DOCID:26577 SCORE: 0.00138739489581871
DOCNO: 11142101
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Disability Evaluation
QUALIFIER: etiology
QUALIFIER: etiology
AUTHOR: T Kühn T
AFFILIATION: Alte Leipziger Lebensversicherung a. G, Alte Leipziger Platz 1, 61440 Oberursel.
PUBTYPE: Journal Article
JOURNALTITLE: Versicherungsmedizin / herausgegeben von Verband der Lebensversicherungs-Unternehmen e.V. und Verband der Privaten Krankenversicherung e.V.
COUNTRY: Germany
TITLE: [Work disability: malignant tumors as markers of noticeable risk in occupational groups]
PUBDATE: 20001201
A risk adequate premium development of private disability insurance requires a correct valuation of the disability probability. If the reasons for disability are known, especially the share of cancer, the development of damage within a job class can be anticipated. For this a relatively small collective is enough. The new findings should be substantiated as far as possible by further analysis and can be the basis for the evaluation of disability probabilities of job classes within the business in force.


11. DOCID:24329 SCORE: 0.00129036505644294
DOCNO: 11082992
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Biopsy, Needle
QUALIFIER: pathology
AUTHOR: J Krawczyk J
AUTHOR: T Krawczyk T
AUTHOR: S Lukaszek S
AFFILIATION: Instytut Centrum Zdrowia Matki Polki.
PUBTYPE: Journal Article
JOURNALTITLE: Ginekologia polska.
COUNTRY: POLAND
TITLE: [Diagnostic value of fine needle aspiration biopsy in breast cancer diagnosis (cytohistological correlation): preliminary note]
PUBDATE: 20000901
A valuation trial of the usefulness of fine needle aspiration biopsy in breast cancer diagnosis attempted. The absence of false positive results, high sensitivity (84%), low price and short time of diagnosis allow omitting the intraoperative or open biopsy in the case of surgical treatment or initial chemotherapy.


12. DOCID:26981 SCORE: 0.00129036302523132
DOCNO: 9843660
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: genetics
QUALIFIER: genetics
QUALIFIER: methods
AUTHOR: G Lucotte G
AUTHOR: G Mercier G
AUTHOR: A Burckel A
AFFILIATION: Regional Center of Neurogenetics, Service of Neurology, Maison Blanche Hospital, 45 rue Cognacq-Jay, Reims, France.
PUBTYPE: Journal Article
JOURNALTITLE: Molecular and cellular probes.
COUNTRY: ENGLAND
TITLE: The use of nested RT-PCR of prostate-specific membrane antigen in blood cells: implications for the detection of haematogenous neoplastic cells in patients with prostate adenocarcinoma.
PUBDATE: 19981201
The aim of this study was to determine the presence of haematogenous neoplastic cells in patients with prostate cancer. Circulating prostate cells can be detected in cancer patients by using a nested-reverse transcriptase-polymerase chain reaction assay (RT-PCR), for prostate-specific membrane (PSM) antigen mRNA. This sensitive nested RT-PCR assay may play a crucial role in the administration of adjuvant therapy of patients with prostate adenocarcinoma.


13. DOCID:27558 SCORE: 0.00129035578672634
DOCNO: 11195421
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: etiology
QUALIFIER: complications
AUTHOR: P Sabbatini P
AFFILIATION: Gynecology Section, Solid Tumor Division, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Oncology (Williston Park, N.Y.)
COUNTRY: United States
TITLE: Contribution of anemia to fatigue in the cancer patient.
PUBDATE: 20001101
One of the goals of the proposed National Comprehensive Cancer Network Practice Guidelines for Cancer-Related Fatigue is outlining a systematic approach to the evaluation, intervention, and assessment of outcome in the treatment of fatigue. Anemia has been characterized as a major contributor to fatigue, and a review of patients receiving cancer therapy showed that the majority developed anemia. The current data support the value of returning hemoglobin levels to the normal range in terms of maximizing improvements in quality of life related to anemia. The potential impact of anemia in terms of treatment outcome is under investigation.


14. DOCID:27816 SCORE: 0.00102207313242141
DOCNO: 10528565
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: prevention & control
QUALIFIER: adverse effects
AUTHOR: G E Kaugars GE
AUTHOR: L M Abbey LM
AUTHOR: D G Page DG
AUTHOR: J A Svirsky JA
AUTHOR: J C Burns JC
AUTHOR: T Pillion T
AFFILIATION: Department of Oral Pathology, Medical College of Virginia, Richmond 23298-0566, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Journal of the California Dental Association.
COUNTRY: UNITED STATES
TITLE: Prevention and detection of lip cancer--the dentist's role.
PUBDATE: 19990401
With their attention to the oral area, dentists are in an excellent position not only to diagnose lip cancer, but also to counsel patients in its prevention. Patients need to be educated on the dangers of ultraviolet radiation and the measures available to decrease exposure to it. This article discusses the circumstances that increase the chance of developing lip cancer, the variety of ways to decrease that chance, and the recognition and treatment of premalignant and malignant lip lesions.