0. DOCID:25581 SCORE: 0.00236567493147002
DOCNO: 11577673
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
QUALIFIER: prevention & control
QUALIFIER: prevention & control
AUTHOR: B F Barker BF
AUTHOR: G J Barker GJ
AFFILIATION: Department of Oral and Maxillofacial Pathology, University of Missouri-Kansas City School of Dentistry, USA. barkerb@umkc.edu
PUBTYPE: Journal Article
JOURNALTITLE: Journal of the California Dental Association.
COUNTRY: United States
TITLE: Oral management of the patient with cancer in the head and neck region.
PUBDATE: 20010801
Cancer therapies--including surgery, radiation, and chemotherapy--may unfavorably affect the oral/dental health of patients. Existing dental problems can also result in serious complications that may be prevented by dental intervention prior to cancer therapy. This paper will be limited to a discussion of the detrimental effects of radiation therapy on the oral cavity and salivary glands and appropriate dental management.

1. DOCID:26461 SCORE: 0.00207746634095906
DOCNO: 12013537
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
AUTHOR: G W Sledge GW
AFFILIATION: Indiana University School of Medicine, Indianapolis, USA. gsledge@iupui.edu
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Journal of mammary gland biology and neoplasia.
COUNTRY: United States
TITLE: Breast cancer in the clinic: treatments past, treatments future.
PUBDATE: 20011001
Therapeutic options for the patient with systemic breast cancer were long limited to either chemotherapy and hormonal therapy. While these therapies provide palliation for many patients with advanced disease, and occasionally cure the patient with micrometastatic disease, they are not optimal either with regard to toxicity or efficacy. This paper reviews the past of systemic therapy (chemotherapy and hormonal therapy), then discusses developing treatment strategies. These strategies include the recently introduced anti-HER-2 antibody trastuzumab, novel agents targeting other aspects of tumor growth mechanisms, as well as agents blocking angiogenesis.

2. DOCID:27513 SCORE: 0.00182801215060964
DOCNO: 9528237
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: transplantation
QUALIFIER: surgery
AUTHOR: T Kaneko T
AUTHOR: S Uemura S
AUTHOR: H Harada H
AUTHOR: S Sugihara S
AUTHOR: T Egami T
AFFILIATION: Department of Surgery, Shimonoseki Kousei Hospital, Yamaguchi, Japan.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Kyobu geka. The Japanese journal of thoracic surgery.
COUNTRY: JAPAN
TITLE: [A case of acute empyema who underwent omentopexy and was found to have gastric cancer during operation]
PUBDATE: 19980301
A 76-year-old man had undergone omentopexy for empyema. He was found to have gastric cancer and revealed Borrmann III by gastroendoscopy intraoperative period. Segmental gastrectomy was performed without dissection of lymph nodes, because his general condition was poor. After operation, the patient showed septic shock, ARDS and hepato-renal failure but his condition was getting improved by conservative therapy. After 5 years later, he was examined gastro-endoscopy, abdominal and chest CT and revealed no recurrence sign.

3. DOCID:30487 SCORE: 0.0015603064886632
DOCNO: 16009521
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: chemistry
QUALIFIER: pharmacology
QUALIFIER: chemistry
AUTHOR: Gordon M Cragg GM
AUTHOR: David J Newman DJ
AFFILIATION: Natural Products Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, P.O. Box B, Frederick, MD 21702-1201, USA. cragg@mail.nih.gov
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Journal of ethnopharmacology.
COUNTRY: Ireland
TITLE: Plants as a source of anti-cancer agents.
PUBDATE: 20050801
Plant-derived compounds have been an important source of several clinically useful anti-cancer agents. These include vinblastine, vincristine, the camptothecin derivatives, topotecan and irinotecan, etoposide, derived from epipodophyllotoxin, and paclitaxel (taxol A number of promising new agents are in clinical development based on selective activity against cancer-related molecular targets, including flavopiridol and combretastin A4 phosphate, while some agents which failed in earlier clinical studies are stimulating renewed interest.

4. DOCID:26993 SCORE: 0.00155919843254587
DOCNO: 9646040
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Models, Genetic
QUALIFIER: genetics
QUALIFIER: genetics
AUTHOR: K Shannon K
AFFILIATION: Department of Pediatrics, University of California, San Francisco 94143, USA. kevins@itsa.ucsf.edu
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Environmental health perspectives.
COUNTRY: UNITED STATES
TITLE: Genetic predispositions and childhood cancer.
PUBDATE: 19980601
This article provides an overview of the problem of genetic susceptibility to childhood cancer with a particular emphasis on problems with ascertaining inherited cancer risk and the role of tumor-suppressor gene mutations in cancer predispositions. The association between neurofibromatosis type 1 and childhood leukemia is used to illustrate some of the issues faced by molecular biologists and genetic epidemiologists in identifying and analyzing at-risk individuals. The problem of incomplete penetrance in cancer susceptibility is presented and potential models are discussed. The article concludes with a number of tentative conclusions from existing data and speculations for future studies.

5. DOCID:27001 SCORE: 0.00155919843251899
DOCNO: 10410154
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Protein Biosynthesis
QUALIFIER: complications
QUALIFIER: therapeutic use
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: etiology
QUALIFIER: complications
AUTHOR: H Koshida H
AUTHOR: T Kametani T
AUTHOR: S Masuda S
AFFILIATION: Second Dept. of Internal Medicine, Kohseiren Takaoka Hospital.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [A case of lung cancer with hypercalcemia and renal failure responsive to pamidronate]
PUBDATE: 19990501
A 46-year-old man was diagnosed as Stage IV lung cancer with neck lymph node and bilateral adrenal metastases. He was treated with seven courses of combined chemotherapy (CDDP + etoposide), until he showed extreme hypercalcemia and acute renal failure. The bisphosphonate, pamidronate with elcatonin and prednisolone dramatically lowered his serum calcium level and normalized his renal function. This is a representative case of humoral hypercalcemia of malignancy whose serum calcium could be safely and effectively controlled with pamidronate.

6. DOCID:26111 SCORE: 0.00155918534492885
DOCNO: 10683074
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: D J Booser DJ
AUTHOR: R S Walters RS
AUTHOR: F A Holmes FA
AUTHOR: G N Hortobagyi GN
AFFILIATION: Department of Breast Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston 77030, USA.
PUBTYPE: Clinical Trial
PUBTYPE: Clinical Trial, Phase II
PUBTYPE: Journal Article
JOURNALTITLE: American journal of clinical oncology.
COUNTRY: UNITED STATES
TITLE: Continuous-infusion high-dose leucovorin with 5-fluorouracil and cisplatin for relapsed metastatic breast cancer: a phase II study.
PUBDATE: 20000201
Twelve women with metastatic breast cancer were treated with continuous infusion high dose leucovorin, 5-fluorouracil and cisplatin. Toxicity was severe although the dose was lower than previously described for the treatment of other cancers, and there was little anti-tumor activity. Many other regimens are more effective and less toxic.

7. DOCID:26027 SCORE: 0.00155918534484821
DOCNO: 11579535
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiography
QUALIFIER: secondary
QUALIFIER: radiography
QUALIFIER: secondary
QUALIFIER: radiography
AUTHOR: K Ohno K
AUTHOR: Y Sasaki Y
AFFILIATION: Department of Surgery, Osaka Kosei-Nenkin Hospital, 4-2-78 Fukushima, Fukushima-ku, Osaka, 553-0003, Japan.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society.
COUNTRY: Japan
TITLE: [A case of mediastinal adenocarcinoma of unknown origin presenting as a diffuse tumor shadow in the middle mediastinum]
PUBDATE: 20010701
We report a case of mediastinal adenocarcinoma of unknown origin presenting as a diffuse tumor shadow in the middle mediastinum. Cases of metastasis from cancer of unknown origin to hilar or mediastinal lymph nodes have often been reported. However, our case shows no round shadow indicating an enlarged lymph node, suggesting that the mediastinal adenocarcinoma originated from mediastinal tissue.

8. DOCID:27470 SCORE: 0.00155915859707159
DOCNO: 10757846
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: methods
AUTHOR: J A Ibarra JA
AFFILIATION: Department of Breast Pathology and Cytopathology, MemorialCare Breast Center, Long Beach Memorial Medical Center, Long Beach, California, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Surgical oncology clinics of North America.
COUNTRY: UNITED STATES
TITLE: The pathologist in breast cancer: contemporary issues in the interdisciplinary approach.
PUBDATE: 20000401
The pathologist's contribution to the interdisciplinary team approach in breast cancer management is a cornerstone for decision-making. Continuous communication with the radiologist, surgeon, oncologist, and radiation oncologist is essential. Preoperative diagnosis, surgical specimen work-up with size determination, sentinel lymph node examination, processing forms to facilitate the work-up, and diagnostic templates are some of the items covered in this review of the pathologist's contribution to the interdisciplinary team in breast cancer. Use of diagnostic templates or synoptic reports routinely provide the complete diagnostic information required for treatment decisions.

9. DOCID:24433 SCORE: 0.00154360983677706
DOCNO: 11007245
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Endosonography
QUALIFIER: secondary
QUALIFIER: methods
QUALIFIER: secondary
QUALIFIER: pathology
AUTHOR: T A Woodward TA
AUTHOR: D M Menke DM
AUTHOR: S J Buskirk SJ
AFFILIATION: Division of Gastroenterology, Mayo Clinic Jacksonville, Florida 32224, USA.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: The American journal of gastroenterology.
COUNTRY: UNITED STATES
TITLE: Solitary pelvic nodule: diagnosis of metastatic prostate cancer by endoscopic ultrasound-guided, fine-needle aspiration.
PUBDATE: 20000901
Prostate cancer manifesting as an isolated perirectal mass is a rare occurrence. The following is a report of a single pelvic nodule that was determined to be metastatic prostate cancer by endoscopic ultrasound-guided, fine-needle aspiration.

10. DOCID:24444 SCORE: 0.00154360981951852
DOCNO: 9545192
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Phosphoric Monoester Hydrolases
DESCRIPTOR: Tumor Suppressor Proteins
QUALIFIER: etiology
QUALIFIER: metabolism
AUTHOR: A Smith A
AUTHOR: A Ashworth A
AFFILIATION: Cancer Research Campaign Centre for Cell and Molecular Biology, Section of Gene Function and Regulation, Chester Beatty Laboratories, The Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK. anna@icr.ac.uk
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Current biology : CB.
COUNTRY: ENGLAND
TITLE: Cancer predisposition: where's the phosphate?
PUBDATE: 19980301
Mutations in a protein phosphatase and a protein kinase cause hamartomatous polyposis syndromes, which are characterised by the formation of multiple benign polyps and an increased susceptibility to some types of cancer.

11. DOCID:29255 SCORE: 0.00154327627376209
DOCNO: 14606062
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: methods
QUALIFIER: trends
QUALIFIER: therapy
AUTHOR: Chao Zhang C
AUTHOR: Zhan-Kui Liu ZK
AFFILIATION: Department of General Surgery, Southwest Hospital, Third Military Medical University, Gaotan Yan, Chongqing 400038, China. meizhang6688@yahoo.com.cn
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: World journal of gastroenterology : WJG.
COUNTRY: China
TITLE: Gene therapy for gastric cancer: a review.
PUBDATE: 20031101
Gastric cancer is common in China, and its early diagnosis and treatment are difficult. In recent years great progress has been achieved in gene therapy, and a wide array of gene therapy systems for gastric cancer has been investigated. The present article deals with the general principles of gene therapy and then focuses on how these principles may be applied to gastric cancer.

12. DOCID:26577 SCORE: 0.00138739489581871
DOCNO: 11142101
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Disability Evaluation
QUALIFIER: etiology
QUALIFIER: etiology
AUTHOR: T Kühn T
AFFILIATION: Alte Leipziger Lebensversicherung a. G, Alte Leipziger Platz 1, 61440 Oberursel.
PUBTYPE: Journal Article
JOURNALTITLE: Versicherungsmedizin / herausgegeben von Verband der Lebensversicherungs-Unternehmen e.V. und Verband der Privaten Krankenversicherung e.V.
COUNTRY: Germany
TITLE: [Work disability: malignant tumors as markers of noticeable risk in occupational groups]
PUBDATE: 20001201
A risk adequate premium development of private disability insurance requires a correct valuation of the disability probability. If the reasons for disability are known, especially the share of cancer, the development of damage within a job class can be anticipated. For this a relatively small collective is enough. The new findings should be substantiated as far as possible by further analysis and can be the basis for the evaluation of disability probabilities of job classes within the business in force.

13. DOCID:29757 SCORE: 0.00129127066947615
DOCNO: 11985563
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: standards
AUTHOR: J H F Smith JH
AFFILIATION: Department of Histopathology, Royal Hallamshire Hospital, Sheffield, UK. John.Smith@sth.nhs.uk
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Cytopathology : official journal of the British Society for Clinical Cytology.
COUNTRY: England
TITLE: Bethesda 2001.
PUBDATE: 20020201
The Bethesda system (TBS) for reporting cervical/vaginal cytological diagnoses was originally developed in 1988 at a National Cancer Institute (NCI) workshop convened to consider the benefits of increased standardization in the diagnostic reports provided by cytology laboratories. It rapidly gained acceptance in laboratory practice in the USA and beyond and three years later the NCI sponsored another workshop to assess the use of TBS in practice and consider areas for improvement. Subsequently an illustrated guide was published.

14. DOCID:29415 SCORE: 0.00129123916659974
DOCNO: 15919587
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: genetics
AUTHOR: Duncan M Baird DM
AFFILIATION: Department of Pathology, Cardiff University, Heath Park, Cardiff CF14 4XN, UK. bairddm@cardiff.ac.uk
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Experimental gerontology.
COUNTRY: England
TITLE: New developments in telomere length analysis.
PUBDATE: 20050501
Telomeres provide an essential 'capping' function, which prevents the natural end of a chromosome from being recognised as a simple dsDNA break. The biology of human telomeres is inextricably linked with both cancer and ageing. As such there is considerable interest in determining the length of these essential and dynamic structures. Here I review, from the standpoint of ageing research in humans, the current situation with regards to technologies available to determine telomere length in human cells and tissues.