0. DOCID:25581 SCORE: 0.00236567493147002
DOCNO: 11577673
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
QUALIFIER: prevention & control
QUALIFIER: prevention & control
AUTHOR: B F Barker BF
AUTHOR: G J Barker GJ
AFFILIATION: Department of Oral and Maxillofacial Pathology, University of Missouri-Kansas City School of Dentistry, USA. barkerb@umkc.edu
PUBTYPE: Journal Article
JOURNALTITLE: Journal of the California Dental Association.
COUNTRY: United States
TITLE: Oral management of the patient with cancer in the head and neck region.
PUBDATE: 20010801
Cancer therapies--including surgery, radiation, and chemotherapy--may unfavorably affect the oral/dental health of patients. Existing dental problems can also result in serious complications that may be prevented by dental intervention prior to cancer therapy. This paper will be limited to a discussion of the detrimental effects of radiation therapy on the oral cavity and salivary glands and appropriate dental management.


1. DOCID:21567 SCORE: 0.00236285522807981
DOCNO: 10143480
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: trends
QUALIFIER: supply & distribution
AUTHOR: S Paryani S
AUTHOR: W Scott W
AUTHOR: J Wells J
AUTHOR: D Johnson D
AUTHOR: R Chobe R
AUTHOR: S Schoeppel S
AUTHOR: A Kuruvilla A
AUTHOR: A Deshmukh A
AFFILIATION: Williams Cancer Center, Bapitist Medical Center, Jacksonville, FL, USA.
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of ambulatory care management.
COUNTRY: UNITED STATES
TITLE: The "revolution" in outpatient care.
PUBDATE: 19950701
Although the concept of outpatient care is not a new one, the growth in ambulatory facilities has revolutionized medical care in the United States. The growth in ambulatory surgery centers, imaging centers, and cancer centers in Florida is explored in detail. With the many changes forthcoming in health care, ambulatory care will play an increasing role in delivering good health care at a reasonable cost.


2. DOCID:26461 SCORE: 0.00207746634095906
DOCNO: 12013537
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
AUTHOR: G W Sledge GW
AFFILIATION: Indiana University School of Medicine, Indianapolis, USA. gsledge@iupui.edu
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Journal of mammary gland biology and neoplasia.
COUNTRY: United States
TITLE: Breast cancer in the clinic: treatments past, treatments future.
PUBDATE: 20011001
Therapeutic options for the patient with systemic breast cancer were long limited to either chemotherapy and hormonal therapy. While these therapies provide palliation for many patients with advanced disease, and occasionally cure the patient with micrometastatic disease, they are not optimal either with regard to toxicity or efficacy. This paper reviews the past of systemic therapy (chemotherapy and hormonal therapy), then discusses developing treatment strategies. These strategies include the recently introduced anti-HER-2 antibody trastuzumab, novel agents targeting other aspects of tumor growth mechanisms, as well as agents blocking angiogenesis.


3. DOCID:27513 SCORE: 0.00182801215060964
DOCNO: 9528237
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: transplantation
QUALIFIER: surgery
AUTHOR: T Kaneko T
AUTHOR: S Uemura S
AUTHOR: H Harada H
AUTHOR: S Sugihara S
AUTHOR: T Egami T
AFFILIATION: Department of Surgery, Shimonoseki Kousei Hospital, Yamaguchi, Japan.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Kyobu geka. The Japanese journal of thoracic surgery.
COUNTRY: JAPAN
TITLE: [A case of acute empyema who underwent omentopexy and was found to have gastric cancer during operation]
PUBDATE: 19980301
A 76-year-old man had undergone omentopexy for empyema. He was found to have gastric cancer and revealed Borrmann III by gastroendoscopy intraoperative period. Segmental gastrectomy was performed without dissection of lymph nodes, because his general condition was poor. After operation, the patient showed septic shock, ARDS and hepato-renal failure but his condition was getting improved by conservative therapy. After 5 years later, he was examined gastro-endoscopy, abdominal and chest CT and revealed no recurrence sign.


4. DOCID:18744 SCORE: 0.00167784977014748
DOCNO: 2047875
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Genetic Vectors
DESCRIPTOR: Vaccines, Synthetic
DESCRIPTOR: Vaccinia virus
AUTHOR: B Moss B
AFFILIATION: Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Science.
COUNTRY: UNITED STATES
TITLE: Vaccinia virus: a tool for research and vaccine development.
PUBDATE: 19910601
Vaccinia virus is no longer needed for smallpox immunization, but now serves as a useful vector for expressing genes within the cytoplasm of eukaryotic cells. As a research tool, recombinant vaccinia viruses are used to synthesize biologically active proteins and analyze structure-function relations, determine the targets of humoral- and cell-mediated immunity, and investigate the immune responses needed for protection against specific infectious diseases. When more data on safety and efficacy are available, recombinant vaccinia and related poxviruses may be candidates for live vaccines and for cancer immunotherapy.


5. DOCID:18067 SCORE: 0.00159871895656821
DOCNO: 1370589
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Palliative Care
QUALIFIER: etiology
QUALIFIER: complications
AUTHOR: W Weber W
AFFILIATION: FMH Innere Medizin, speziell Onkologie-Hämatologie, Heuberg, Basel.
PUBTYPE: Journal Article
JOURNALTITLE: Schweizerische Rundschau für Medizin Praxis = Revue suisse de médecine Praxis.
COUNTRY: SWITZERLAND
TITLE: [Respiratory problems in cancer--causes and treatment]
PUBDATE: 19920101
Half of the patients with advanced cancer suffer from shortness of breath. This may be due to the cancer itself, result from its treatment or arise from concurrent conditions. Careful assessment should precede any intervention. Treatment should be directed toward altering the underlying pathological process as far as possible (e.g. tumour reduction or pleural puncture). The relieve of symptoms by reassuring presence and morphine application are the mainstay, when it is not possible to reverse the cause of dyspnea, and can also successfully complement specific therapy.


6. DOCID:18341 SCORE: 0.00159855715562237
DOCNO: 1836053
AUTHOR: P B Lockhart PB
AUTHOR: M J Kutcher MJ
AFFILIATION: Department of Dentistry, Carolinas Medical Center, Charlotte.
PUBTYPE: Journal Article
JOURNALTITLE: North Carolina medical journal.
COUNTRY: UNITED STATES
TITLE: Oral considerations for the cancer patient.
PUBDATE: 19911101
An increasing number of patients are undergoing cancer chemotherapy and/or radiotherapy and are experiencing side effects in their mouths. A thorough oral examination is important in the overall pretherapy evaluation of these patients, and, along with a consideration for the patient's disease, treatment, prognosis and laboratory values, allows for realistic planning for dental management prior to, during and following cancer therapy. The early establishment of a good working relationship with the patient and those caring for him or her, and an understanding of the importance of compliance with oral hygiene will eliminate needless therapy-induced morbidity and mortality.


7. DOCID:21691 SCORE: 0.00156558294937955
DOCNO: 8535902
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Comorbidity
QUALIFIER: secondary
QUALIFIER: therapy
AUTHOR: T A Graves TA
AUTHOR: K I Bland KI
AFFILIATION: Brown University School of Medicine, Providence, Rhode Island, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Surgical oncology clinics of North America.
COUNTRY: UNITED STATES
TITLE: Comorbidity risk parameters associated with advanced breast cancer and systemic disease. Management of nonbreast disease.
PUBDATE: 19951001
The comorbidity risks associated with advanced breast cancer and systemic disease have been outlined under three broad categories: the local or regional consequences of advanced local breast cancer and its management, systemic sequelae of adjuvant chemotherapy and radiotherapy, and systemic sequelae of metastatic breast disease. Awareness of the potential risks, early detection, and active intervention may diminish the adverse consequences of comorbidities in breast cancer and improve the patient's quality of life.


8. DOCID:21428 SCORE: 0.00156557788436984
DOCNO: 9257149
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
AUTHOR: B R Stotland BR
AUTHOR: E S Siegelman ES
AUTHOR: J B Morris JB
AUTHOR: M L Kochman ML
AFFILIATION: Department of Medicine, University of Pennsylvania Health System, Philadelphia, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Hematology/oncology clinics of North America.
COUNTRY: UNITED STATES
TITLE: Preoperative and postoperative imaging for colorectal cancer.
PUBDATE: 19970801
Management and survival in colorectal cancer are dictated by the extent of the disease at the initial diagnosis. Technological advances over the past 25 years have improved the ability to accurately preoperatively stage these lesions and detect recurrence. This article reviews the focus on the utility of computerized tomography, magnetic resonance, endoscopic ultrasound, and newer imaging methods including PET scan and monoclonal antibodies in the management of colorectal carcinoma.


9. DOCID:23940 SCORE: 0.00156557621331775
DOCNO: 8593169
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Genes, src
DESCRIPTOR: Multigene Family
QUALIFIER: genetics
QUALIFIER: physiology
AUTHOR: S J Taylor SJ
AUTHOR: D Shalloway D
AFFILIATION: Section of Biochemistry, Molecular and Cell Biology, Cornell University, Ithaca, NY 14851, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: BioEssays : news and reviews in molecular, cellular and developmental biology.
COUNTRY: ENGLAND
TITLE: Src and the control of cell division.
PUBDATE: 19960101
The finely tuned mechanisms that control cell cycle progression go awry in cancer, pointing to proto-oncogene products as important players in cell-cycle regulation. One such proto-oncoprotein, c-Src, has previously been directly implicated, based on its requirement for growth factor-stimulated DNA synthesis. Roche et al. have now shown that c-Src or its close relatives are also required for cell division to occur. The demonstration of essential functions for the Src family at multiple points in the cell cycle raises important questions about the normal and transforming activities of these and other proto-oncoproteins.


10. DOCID:30487 SCORE: 0.0015603064886632
DOCNO: 16009521
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: chemistry
QUALIFIER: pharmacology
QUALIFIER: chemistry
AUTHOR: Gordon M Cragg GM
AUTHOR: David J Newman DJ
AFFILIATION: Natural Products Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, P.O. Box B, Frederick, MD 21702-1201, USA. cragg@mail.nih.gov
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Journal of ethnopharmacology.
COUNTRY: Ireland
TITLE: Plants as a source of anti-cancer agents.
PUBDATE: 20050801
Plant-derived compounds have been an important source of several clinically useful anti-cancer agents. These include vinblastine, vincristine, the camptothecin derivatives, topotecan and irinotecan, etoposide, derived from epipodophyllotoxin, and paclitaxel (taxol A number of promising new agents are in clinical development based on selective activity against cancer-related molecular targets, including flavopiridol and combretastin A4 phosphate, while some agents which failed in earlier clinical studies are stimulating renewed interest.


11. DOCID:26993 SCORE: 0.00155919843254587
DOCNO: 9646040
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Models, Genetic
QUALIFIER: genetics
QUALIFIER: genetics
AUTHOR: K Shannon K
AFFILIATION: Department of Pediatrics, University of California, San Francisco 94143, USA. kevins@itsa.ucsf.edu
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Environmental health perspectives.
COUNTRY: UNITED STATES
TITLE: Genetic predispositions and childhood cancer.
PUBDATE: 19980601
This article provides an overview of the problem of genetic susceptibility to childhood cancer with a particular emphasis on problems with ascertaining inherited cancer risk and the role of tumor-suppressor gene mutations in cancer predispositions. The association between neurofibromatosis type 1 and childhood leukemia is used to illustrate some of the issues faced by molecular biologists and genetic epidemiologists in identifying and analyzing at-risk individuals. The problem of incomplete penetrance in cancer susceptibility is presented and potential models are discussed. The article concludes with a number of tentative conclusions from existing data and speculations for future studies.


12. DOCID:27001 SCORE: 0.00155919843251899
DOCNO: 10410154
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Protein Biosynthesis
QUALIFIER: complications
QUALIFIER: therapeutic use
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: etiology
QUALIFIER: complications
AUTHOR: H Koshida H
AUTHOR: T Kametani T
AUTHOR: S Masuda S
AFFILIATION: Second Dept. of Internal Medicine, Kohseiren Takaoka Hospital.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [A case of lung cancer with hypercalcemia and renal failure responsive to pamidronate]
PUBDATE: 19990501
A 46-year-old man was diagnosed as Stage IV lung cancer with neck lymph node and bilateral adrenal metastases. He was treated with seven courses of combined chemotherapy (CDDP + etoposide), until he showed extreme hypercalcemia and acute renal failure. The bisphosphonate, pamidronate with elcatonin and prednisolone dramatically lowered his serum calcium level and normalized his renal function. This is a representative case of humoral hypercalcemia of malignancy whose serum calcium could be safely and effectively controlled with pamidronate.


13. DOCID:26111 SCORE: 0.00155918534492885
DOCNO: 10683074
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: D J Booser DJ
AUTHOR: R S Walters RS
AUTHOR: F A Holmes FA
AUTHOR: G N Hortobagyi GN
AFFILIATION: Department of Breast Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston 77030, USA.
PUBTYPE: Clinical Trial
PUBTYPE: Clinical Trial, Phase II
PUBTYPE: Journal Article
JOURNALTITLE: American journal of clinical oncology.
COUNTRY: UNITED STATES
TITLE: Continuous-infusion high-dose leucovorin with 5-fluorouracil and cisplatin for relapsed metastatic breast cancer: a phase II study.
PUBDATE: 20000201
Twelve women with metastatic breast cancer were treated with continuous infusion high dose leucovorin, 5-fluorouracil and cisplatin. Toxicity was severe although the dose was lower than previously described for the treatment of other cancers, and there was little anti-tumor activity. Many other regimens are more effective and less toxic.


14. DOCID:26027 SCORE: 0.00155918534484821
DOCNO: 11579535
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiography
QUALIFIER: secondary
QUALIFIER: radiography
QUALIFIER: secondary
QUALIFIER: radiography
AUTHOR: K Ohno K
AUTHOR: Y Sasaki Y
AFFILIATION: Department of Surgery, Osaka Kosei-Nenkin Hospital, 4-2-78 Fukushima, Fukushima-ku, Osaka, 553-0003, Japan.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society.
COUNTRY: Japan
TITLE: [A case of mediastinal adenocarcinoma of unknown origin presenting as a diffuse tumor shadow in the middle mediastinum]
PUBDATE: 20010701
We report a case of mediastinal adenocarcinoma of unknown origin presenting as a diffuse tumor shadow in the middle mediastinum. Cases of metastasis from cancer of unknown origin to hilar or mediastinal lymph nodes have often been reported. However, our case shows no round shadow indicating an enlarged lymph node, suggesting that the mediastinal adenocarcinoma originated from mediastinal tissue.