0. DOCID:2958 SCORE: 0.00542164372503239
DOCNO: 328139
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
QUALIFIER: therapy
AUTHOR: R J Johnson RJ
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
PUBTYPE: Randomized Controlled Trial
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Gastrointestinal cancer--colon (surgery-radiotherapy). The role of radiation therapy in the management of rectosigmoid cancer.
PUBDATE: 19770701
The lack of an improvement in the gross survival statistics for colorectal cancer during the last decade and the negative results of randomized trials, suggests that 5-FU used as an adjuvant treatment has not increased survival. Current chemotherapeutic drug combinations, however, may prove effective in the adjuvant situation. The adjuvant use of preoperative radiation has shown improved survival in one randomized study and no change in the second study. Current preoperative radiotherapy studies using a more effective radiation dose will confirm the effect of preoperative radiation both on the primary tumor control and on metastases. Current postoperative adjuvant trials incorporating radiation, chemotherapy or a combination of the two, when completed, will provide clear indications for the physician as to the optimum treatment of Duke's B and C cancer of the colorectum. Three national randomized studies for inoperable, recurrent or residual carcinoma of the colorectum are testing the effect of radiation alone or in combination with chemotherapy or chemotherapy followed by immunotherapy.


1. DOCID:2882 SCORE: 0.00187579879835622
DOCNO: 1133845
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: immunology
QUALIFIER: immunology
QUALIFIER: immunology
QUALIFIER: analysis
QUALIFIER: analysis
AUTHOR: A L Dellon AL
AUTHOR: G N Rogentine GN
AUTHOR: P B chretien PB
PUBTYPE: Journal Article
JOURNALTITLE: Journal of the National Cancer Institute.
COUNTRY: UNITED STATES
TITLE: Prolonged survival in bronchogenic carcinoma associated with HL-A antigens W-19 and HL-A5: a preliminary report.
PUBDATE: 19750601
The HL-A antigens were determined retrospectively in a group of 14 surgically cured bronchogenic carcinoma patients and prospectively in another group of 100 untreated patients. In the retrospective group, the frequencies of antigens W-19 and HL-A5 were significantly increased when compared with the noncancer control and the prospective lung cancer populations. In the latter group, 60% of the patients with W-19 and 58% with HL-A5 survived without evidence of tumor for at least 1 year after treatment compared with 15% of patients with neither of these antigens, P less than 0.01 and 0.005, respectively. These comparisons were for adenocarcinoma and squamous carcinoma. The patient groups for oat cell and undifferentiated carcinoma were too small for valid statistical comparisons. This preliminary study suggests that the presence of HL-A antigens W-19 and HL-A5 confers resistance to dissemination of bronchogenic carcinoma.


2. DOCID:169 SCORE: 0.0018732712468495
DOCNO: 1135726
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Ethnic Groups
QUALIFIER: mortality
AUTHOR: E Bradshaw E
AUTHOR: J S Harington JS
PUBTYPE: Journal Article
JOURNALTITLE: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.
COUNTRY: SOUTH AFRICA
TITLE: The changing pattern of cancer mortality in South Africa, 1949-1969.
PUBDATE: 19750501
Cancer mortality rates for Whites, Coloureds and Asians for the period of 1949 - 1969 have been analysed, and a changing pattern has been found. Some comparisons with other countries have been made, and the risk for each race group has been delineated for cancers at the commonest sites.


3. DOCID:1139 SCORE: 0.00173290494200514
DOCNO: 1267497
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Axilla
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: R Ashikari R
AUTHOR: P P Rosen PP
AUTHOR: J A Urban JA
AUTHOR: T Senoo T
PUBTYPE: Journal Article
JOURNALTITLE: Annals of surgery.
COUNTRY: UNITED STATES
TITLE: Breast cancer presenting as an axillary mass.
PUBDATE: 19760401
Experience with breast cancer presenting as an axillary mass in 42 patients has been reviewed according to initial clinical findings, treatment and survival. In the absence of an obvious inflammatory lesion, an axillary node may prove to be the first sign of breast cancer. It has been demonstrated that such a node should be biopsied and if positive for adenocarcinoma, a radical mastectomy performed presuming other primary sites have been ruled out. The survival rate after surgery in this group of patients is better than in those who present with a palpable breast mass and have axillary metastases.


4. DOCID:8689 SCORE: 0.0016276491801707
DOCNO: 3913993
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Ultrasonography
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: G Gardellin G
AUTHOR: B Perin B
AUTHOR: F Lunghi F
AUTHOR: P Frasson P
AUTHOR: D Celi D
PUBTYPE: Journal Article
JOURNALTITLE: La Radiologia medica.
COUNTRY: ITALY
TITLE: [Preoperative ultrasonic diagnosis of metastasis to the cervical lymph nodes from otorhinolaryngeal neoplasms]
PUBDATE: 19851201
The results of a study on 30 patients with ear, nose and throat cancers are discussed; a comparison of clinical, ultrasound and histological findings for the preoperatory evaluation of the cervical lymph nodes has been carried out. Ultrasound technique is an excellent method of investigation for the staging "N" of such neoplasms; its contribution is very important for the following therapeutic program.


5. DOCID:10823 SCORE: 0.00150724110798893
DOCNO: 6580489
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analysis
QUALIFIER: immunology
QUALIFIER: immunology
AUTHOR: O F Dent OF
AUTHOR: P H Chapuis PH
AUTHOR: J E Payne JE
AUTHOR: J Meyer J
AUTHOR: A M Sutherland AM
AUTHOR: K J Goulston KJ
PUBTYPE: Journal Article
JOURNALTITLE: Journal of the National Cancer Institute.
COUNTRY: UNITED STATES
TITLE: Immunodiagnosis of colorectal cancer: clinical evaluation of Tennessee antigen (Tenagen).
PUBDATE: 19831101
Blood samples from 172 consecutive patients undergoing complete colon investigations to exclude colorectal cancer (CC) were examined for levels of Tennessee antigen, i.e., Tenagen (Tg), and carcinoembryonic antigen. Patients included 48 with CC, 34 with adenomatous polyps, 14 with colitis, and 76 with no organic mucosal disease. All patients were investigated by the one clinical and histopathology department. Laboratory estimations were performed blindly. Although there were some statistically significant differences among average values, the degree of overlap among the groups of patients precludes the practical application of Tg in the diagnosis of CC.


6. DOCID:2265 SCORE: 0.00150490579970461
DOCNO: 409481
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: B S Schoenberg BS
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Multiple primary neoplasms and the nervous system.
PUBDATE: 19771001
Studies of multiple primary neoplasms and their relation to the nervous system should consider two important principles: 1) neoplasms of the nervous system have certain unusual features that distinguish them from tumors occurring elsewhere in the body; and 2) there is good evidence that the various histologic types of nervous system tumors should be regarded as separate diseases. The association of nervous system neoplasms and tumors of other sites may occur in patients with phacomatoses or particular genetic syndromes. In addition, certain nervous system neoplasms may be multicentric in origin. Retinoblastoma and osteosarcoma occur together in the same patient more often than expected by chance, as do meningioma and breast cancer. These relationships are important in that they serve to identify the high risk patient, may provide etiologic clues, may point to the presence of genetic syndromes, and may highlight sites in which subsequent tumors are most likely to develop.


7. DOCID:7193 SCORE: 0.00143461071480198
DOCNO: 203902
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
AUTHOR: E P Fazzini EP
PUBTYPE: Journal Article
JOURNALTITLE: Postgraduate medicine.
COUNTRY: UNITED STATES
TITLE: Lung cancer: the pathologist's role in management.
PUBDATE: 19780201
The prognosis of lung cancer is poor, although there is hope for improvement based on early detection through cytologic screening and the use of newer treatment protocols. Although there are difficulties inherent in classifying tumors by type on the basis of very small samples of lesions that are not necessarily homogeneous, the pathologist should use a standard classification that sets forth definite criteria for the differentiated types. Among the common tumors, a small, well-differentiated epidermoid carcinoma with no evidence of lymph node involvement has the most favorable prognosis, and a small-cell anaplastic or oat cell carcinoma the worst. Results of therapy for tumors of other types show much variation. Future studies of lung cancer should include careful clinical staging and, when resection is done, pathologic staging. More study of the immunomorphology of lymph nodes is needed, as this may provide highly useful prognostic information.


8. DOCID:7772 SCORE: 0.00136147878087502
DOCNO: 534827
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: etiology
QUALIFIER: adverse effects
AUTHOR: H M Spence HM
AUTHOR: W W Hoffman WW
AUTHOR: G P Fosmire GP
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: British journal of urology.
COUNTRY: ENGLAND
TITLE: Tumour of the colon as a late complication of ureterosigmoidostomy for exstrophy of the bladder.
PUBDATE: 19791201
Two cases of cancer of the colon have occurred recently in our series of 38 patients with exstrophy of the bladder treated by ureterosigmoidostomy. Twenty-six and 14 years elapsed between the original operation and the diagnosis of malignancy. Since 1929 the literature contains reports of 55 patients who have developed bowel neoplasms as a late complication of this form of diversion. The operation was performed for exstrophy in 35 of these, in whom the resulting tumour at the anastomotic site was malignant in 28 and benign in 7 patients. The shortest interval between ureterosigmoidostomy and recognition of the growth was 10 years with a mean latent period of 25 years. The aetiology remains uncertain but it is clear that long-term survivors after ureterosigmoidostomy should have diagnostic large bowel studies included in the follow-up.


9. DOCID:7698 SCORE: 0.00136112455365395
DOCNO: 6173052
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Hypophysectomy
DESCRIPTOR: Hypophysectomy, Chemical
DESCRIPTOR: Palliative Care
QUALIFIER: secondary
QUALIFIER: therapy
AUTHOR: J W Lloyd JW
AUTHOR: W A Rawlinson WA
AUTHOR: P J Evans PJ
PUBTYPE: Journal Article
JOURNALTITLE: British journal of anaesthesia.
COUNTRY: ENGLAND
TITLE: Selective hypophysectomy for metastatic pain. A review of ethyl alcohol ablation of the anterior pituitary in a Regional Pain Relief Unit.
PUBDATE: 19811101
Selective adenohypophysectomy, by the injection of up to 1 ml of absolute alcohol to the pituitary gland, was used to produce pain relief in 25 patients suffering from metastatic cancer. Thirty-five treatments were given and good analgesia was obtained in 74%. The median duration of pain relief was 6-7 weeks, although some treatments produced relief for up to 20 months. The procedure was most successful in relieving bone pain in patients with advanced carcinoma of the breast or prostate. The use of a fine-gauge needle for the intranasal trans-sphenoidal approach to the gland and the injection of alcohol to the anterior part (pars distalis) of the gland reduced the frequency of the major complications diabetes insipidus (17%) and prolonged visual disturbance (3%).


10. DOCID:14503 SCORE: 0.00135800924625896
DOCNO: 3672085
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
AUTHOR: P Leuenberger P
AFFILIATION: Centre hospitalier universitaire vaudois, Lausanne.
PUBTYPE: Journal Article
JOURNALTITLE: Schweizerische medizinische Wochenschrift.
COUNTRY: SWITZERLAND
TITLE: [Evaluation of the extension of bronchial carcinoma: strategy proposals]
PUBDATE: 19870901
The diagnostic approach in a patient with lung cancer should be oriented according to the mode of presentation of the disease. The first step includes history and clinical examination of the patient, and frontal and lateral chest X-ray, before histological typing of the tumor. The various diagnostic methods are selected according to localization of the mass in the thorax, and staging procedures are determined by the type of the tumor and the possible therapies available. The complexity of the problems surrounding patients with lung cancer mean that the general practitioner should seek the opinion of the chest specialist early rather than late in the pretherapeutic evaluation.


11. DOCID:11769 SCORE: 0.00134703987668015
DOCNO: 6229743
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
AUTHOR: P Cappelaere P
AUTHOR: A Demaille A
PUBTYPE: Journal Article
JOURNALTITLE: Presse m├ędicale (Paris, France : 1983)
COUNTRY: FRANCE
TITLE: [Cancer and pregnancy]
PUBDATE: 19840101
During the last decades, our ideas on the cancer-pregnancy association have been radically altered. Induced abortion, which has long been considered a prerequisite to successful treatment of cancer in such cases, is now performed only if requested by a fully informed mother or if embryotoxic chemotherapy is required. Many authors disagree that pregnancy has detrimental effects on cancer and believe that this only applies to breast cancers with axillary lymph mode involvement. Epidemiologists have shown that obstetrical factors are closely related to the risks of breast, endometrial and ovarian cancers. In some cancers, particularly in children and young adults, cure cannot be considered complete it has been obtained at the cost of infertility. To preserve fertility without reducing the prospects of cure is one of the major objectives of treatment in young cancerous patients.


12. DOCID:9452 SCORE: 0.00134694935310173
DOCNO: 3968292
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Facial Nerve Injuries
AUTHOR: W J Grabski WJ
AUTHOR: S J Salasche SJ
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of dermatologic surgery and oncology.
COUNTRY: UNITED STATES
TITLE: Management of temporal nerve injuries.
PUBDATE: 19850201
Transection of the temporal branch of the facial nerve results in paralysis of the frontalis muscle with subsequent inability to wrinkle the forehead. In addition there is ptosis of the eyebrow with upper visual field defects. The intent of this article is to outline an orderly, rational approach to the management of such injuries based on our experience with seven patients whose nerve was damaged during Mohs surgery for cancer ablation. Repair options include various combinations of direct brow-plasty, indirect temporal or coronal browlifts, and adjunctive upper lid blepharoplasty.


13. DOCID:4834 SCORE: 0.00134107210320401
DOCNO: 7356527
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: mortality
QUALIFIER: mortality
QUALIFIER: mortality
AUTHOR: M R Greenberg MR
AUTHOR: J Caruana J
AUTHOR: B Holcomb B
AUTHOR: G Greenberg G
AUTHOR: R Parker R
AUTHOR: J Louis J
AUTHOR: P White P
PUBTYPE: Journal Article
JOURNALTITLE: Cancer research.
COUNTRY: UNITED STATES
TITLE: High cancer mortality rates from childhood leukemia and young adult Hodgkin's disease and lymphoma in the New Jersey-New York-Philadelphia Metropolitan Corridor, 1950 to 1969.
PUBDATE: 19800201
In comparison to the United States as a whole and to their total population age-adjusted rates, the New Jersey-New York-Philadelphia Metropolitan Region was found to have excessively high childhood leukemia and high young adult Hodgkin's disease and lymphoma cancer mortality rates in the period from 1950 to 1969.


14. DOCID:217 SCORE: 0.00132781821723841
DOCNO: 1263319
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Seminal Vesicles
QUALIFIER: diagnosis
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: C K Carris CK
AUTHOR: A P McLaughlin AP
AUTHOR: R F Gittes RF
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of urology.
COUNTRY: UNITED STATES
TITLE: Amyloidosis of the lower genitourinary tract.
PUBDATE: 19760401
Three patients with amyloidosis of the lower genitourinary tract are described. In the cases of primary localized amyloidosis of the urethra and primary systemic amyloidosis involving the prostate the clinical presentation mimicked cancer of the respective sites. In the case of secondary localized amyloidosis of the seminal vesicles chronic perineal pain suggested seminal vesiculitis.