0. DOCID:31319 SCORE: 0.00311012224593751
DOCNO: 12087457
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Air Pollution, Indoor
DESCRIPTOR: Environmental Exposure
DESCRIPTOR: Gamma Rays
DESCRIPTOR: Housing
PUBTYPE: Journal Article
PUBTYPE: Multicenter Study
JOURNALTITLE: British journal of cancer.
COUNTRY: Scotland
TITLE: The United Kingdom Childhood Cancer Study of exposure to domestic sources of ionising radiation: 2: gamma radiation.
PUBDATE: 20020601
This article reports measurements of household levels of gamma and cosmic rays at the addresses of children with cancer at the time of diagnosis and six months before, and of similar data at the addresses of control children. There is no indication of increased risk with increasing dose rates either in matched or unmatched analyses, with or without adjustment for deprivation. Sub-division by diagnostic group did not reveal any association with any specific types of malignancy. Studies of the relationship between household gamma rays and radon concentration show no evidence of any interactions.


1. DOCID:25916 SCORE: 0.00203200495167608
DOCNO: 10568682
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: adverse effects
QUALIFIER: drug therapy
QUALIFIER: chemically induced
AUTHOR: A Gurjal A
AUTHOR: T An T
AUTHOR: M Valdivieso M
AUTHOR: G P Kalemkerian GP
AFFILIATION: The Department of Internal Medicine, Wayne State University and the Barbara Ann Karmanos Cancer Institute, Detroit, MI, USA.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Lung cancer (Amsterdam, Netherlands)
COUNTRY: IRELAND
TITLE: Etoposide-induced pulmonary toxicity.
PUBDATE: 19991101
After treatment with etoposide, two patients with lung cancer developed interstitial infiltrates and respiratory failure. Of the two, one patient responded rapidly to steroid therapy and developed recurrent symptoms on re-challenge with etoposide. Both patients had histopathologic findings consistent with drug-induced pulmonary toxicity. Etoposide-induced lung disease needs to be considered in patients who develop subacute dyspnea and interstitial infiltrates during treatment with this agent.


2. DOCID:25944 SCORE: 0.0020320037097106
DOCNO: 9810418
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: M Pawlicki M
AUTHOR: J Rolski J
AUTHOR: B Wiczyńska B
AUTHOR: U Rychlik U
AFFILIATION: Kliniki Chemioterapii Centrum Onkologii, Oddział w Krakowie.
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
JOURNALTITLE: Ginekologia polska.
COUNTRY: POLAND
TITLE: [Evaluation of efficacy and toxicity of PC chemotherapy (cisplatin, cyclophosphamide) administered with amifostine in patients with clinically advanced ovarian cancer]
PUBDATE: 19980701
Twenty patients with advanced ovarian cancer were treated with chemotherapy PC (cisplatin 100 mg/m2, cyclophosphamide 1000 mg/m2) administered with amifostine. Sixty five percent of patients had objective response with 25% complete response rate. Tolerance of treatment was satisfactory. Only in 1 patients side effects were the reason of treatment interruption. Amifostine markedly decreases chemotherapy toxicity, mainly hematological and does not seem to influence the efficacy of chemotherapy.


3. DOCID:26356 SCORE: 0.00169778629591597
DOCNO: 11090989
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Plants, Medicinal
QUALIFIER: therapy
AUTHOR: J G Graham JG
AUTHOR: M L Quinn ML
AUTHOR: D S Fabricant DS
AUTHOR: N R Farnsworth NR
AFFILIATION: Program for Collaborative Research in the Pharmaceutical Sciences, College of Pharmacy, 833 South Wood Street, Chicago IL 60612, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Journal of ethnopharmacology.
COUNTRY: IRELAND
TITLE: Plants used against cancer - an extension of the work of Jonathan Hartwell.
PUBDATE: 20001201
A survey of plants used ethnomedically against cancer was undertaken, using the NAPRALERT database currently maintained by the Program for Collaborative Research in the Pharmaceutical Sciences, College of Pharmacy, University of Illinois-Chicago. We report over 350 species which are reported to be used against cancer and not cited in the work of Jonathan Hartwell, "Plants used against cancer: a survey", including previously unrepresented genera and families.


4. DOCID:30385 SCORE: 0.00168274290784681
DOCNO: 15024383
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analogs & derivatives
QUALIFIER: metabolism
QUALIFIER: metabolism
AUTHOR: Hirofumi Tachibana H
AUTHOR: Kiyoshi Koga K
AUTHOR: Yoshinori Fujimura Y
AUTHOR: Koji Yamada K
AFFILIATION: Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, Hakozaki 6-10-1, Fukuoka, 812-8581, Japan. tatibana@agr.kyushu-u.ac.jp
PUBTYPE: Journal Article
JOURNALTITLE: Nature structural & molecular biology.
COUNTRY: United States
TITLE: A receptor for green tea polyphenol EGCG.
PUBDATE: 20040401
The major polyphenol in green tea, (-)-epigallocatechin-3-gallate (EGCG), has been shown to prevent carcinogenesis. We have identified a receptor that mediates the anticancer activity of EGCG. Expression of the metastasis-associated 67-kDa laminin receptor confers EGCG responsiveness to cancer cells at physiologically relevant concentrations. Experiments using surface plasmon resonance demonstrate binding of EGCG to the 67-kDa laminin receptor with a nanomolar K (d) value.


5. DOCID:27161 SCORE: 0.00140502718780324
DOCNO: 10922963
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: etiology
AUTHOR: J P Labat JP
AUTHOR: H Simon H
AUTHOR: J P Metges JP
AUTHOR: B Lucas B
AUTHOR: J P Malhaire JP
AFFILIATION: Fédération de Cancérologie, CHU - Hôpital Morvan, 5, avenue Foch, 29200 Brest. Jean-Paul.Labat@univ-brest.fr
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Annales de médecine interne.
COUNTRY: FRANCE
TITLE: [Pyoderma gangrenosum and breast cancer: a new case]
PUBDATE: 20000601
We report here a new case of pyoderma gangrenosum (PG) associated with a breast cancer in a 39-year-old woman. We only found in literature three other reports of this rare entity which seems usually to be associated with monoclonal gammopathy, gastro-intestinal diseases such as Crohn's disease, chronic ulcerative colitis, leukemias or rheumatologic diseases. A commun hapten between of tumor and skin may explain the origin of this inflammatory lesion. In our case, PG could be a paraneoplastic syndrome.


6. DOCID:25455 SCORE: 0.00140488348871843
DOCNO: 11516603
AUTHOR: S Krishna S
AUTHOR: V T Chang VT
AUTHOR: J A Shoukas JA
AUTHOR: J Donahoo J
AFFILIATION: Department of Medicine, University of Medicine and Dentistry New Jersey/New Jersey Medical School, Newark, NJ 07018, USA.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Journal of pain and symptom management.
COUNTRY: United States
TITLE: Video-assisted thoracoscopic sympathectomy-splanchnicectomy for pancreatic cancer pain.
PUBDATE: 20010701
Patients with unresectable pancreatic cancer often suffer severe pain. Various techniques are available for pain control. We present a patient with pancreatic cancer who underwent unilateral video-assisted thoracoscopic sympathectomy-splanchnicectomy and had complete pain relief. This minimally invasive procedure offers promise in carefully selected patients with severe pain from pancreatic cancer and other conditions which are not amenable to conventional interventions.


7. DOCID:24927 SCORE: 0.00140487098426381
DOCNO: 11411565
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: chemistry
QUALIFIER: pharmacology
AUTHOR: P Magiatis P
AUTHOR: H Pratsinis H
AUTHOR: E Kalpoutzakis E
AUTHOR: A Konstantinidou A
AUTHOR: P Davaris P
AUTHOR: A L Skaltsounis AL
AFFILIATION: Department of Pharmacy, University of Athens, Greece.
PUBTYPE: Journal Article
JOURNALTITLE: Biological & pharmaceutical bulletin.
COUNTRY: Japan
TITLE: Hydrolyzable tannins, the active constituents of three Greek Cytinus taxa against several tumor cell lines.
PUBDATE: 20010601
Hydrolyzable tannins were found to be the active cytotoxic constituents of three Greek Cytinus taxa: Cytinus ruber, Cytinus hypocistis subsp. hypocistis and Cytinus hypocistis subsp. orientalis. The cytotoxic activity was evaluated against a broad spectrum of cancer cell lines. The structure of the active compounds was investigated with NMR and electrospray-MS/MS techniques.


8. DOCID:24957 SCORE: 0.00140487098414672
DOCNO: 11768872
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: blood
QUALIFIER: blood
PUBTYPE: Newspaper Article
JOURNALTITLE: TreatmentUpdate.
COUNTRY: Canada
TITLE: Looking at soluble CD23 levels to predict lymphoma.
PUBDATE: 20011001
As we noted in our first article on lymphoma, there isn't any quick and simple test to diagnose or predict which PHAs will develop this cancer. Nor are there any symptoms that specifically occur from having lymphoma. To try to remedy the situation, researchers in Italy have been monitoring levels of the a protein called soluble CD23 (sCD23) in the blood and fluid surrounding the brain--cerebrospinal fluid (CSF). They have found higher-than-normal levels of sCD23 in the CSF of PHAs who have brain lymphoma.


9. DOCID:29269 SCORE: 0.00139316388380331
DOCNO: 11940467
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: administration & dosage
QUALIFIER: drug therapy
QUALIFIER: administration & dosage
AUTHOR: Mario Campone M
AUTHOR: Pierre Fumoleau P
AFFILIATION: Service d'oncologie, Centre René-Gauducheau, boulevard Jacques-Monod, 44805 Saint-Herblain Cedex.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Bulletin du cancer.
COUNTRY: France
TITLE: [Weekly administration of paclitaxel in the treatment of metastatic breast cancer: from rational to practice]
PUBDATE: 20020301
Clinical studies showed that paclitaxel is active as single agent and in combination chemotherapy for the management of metastatic breast cancer. A variety of doses and administration schedules have been evaluated in phase II and III trials. Weekly administration of paclitaxel which is generally well tolerated increases the therapeutic index (efficacy/safety) resulting from anti-angiogenic and pro-apoptotic effects.


10. DOCID:29423 SCORE: 0.00139283350556052
DOCNO: 15533503
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Laparoscopy
QUALIFIER: surgery
QUALIFIER: injuries
QUALIFIER: surgery
QUALIFIER: adverse effects
QUALIFIER: surgery
AUTHOR: Massimiliano Spaliviero M
AUTHOR: Andrew P Steinberg AP
AUTHOR: Jihad H Kaouk JH
AUTHOR: Mihir M Desai MM
AUTHOR: Warren C Hammert WC
AUTHOR: Inderbir S Gill IS
AFFILIATION: Section of Laparoscopic and Minimally Invasive Surgery, Glickman Urological Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Urology.
COUNTRY: United States
TITLE: Laparoscopic injury and repair of obturator nerve during radical prostatectomy.
PUBDATE: 20041101
A 61-year-old man with bilateral Gleason score 7 (3+4) clinical Stage T1c prostate cancer was treated with laparoscopic bilateral pelvic lymphadenectomy and radical prostatectomy. The left obturator nerve was inadvertently transected during left obturator lymph node dissection and repaired by laparoscopic reapproximation.


11. DOCID:29695 SCORE: 0.00139281365226014
DOCNO: 16124750
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: isolation & purification
QUALIFIER: isolation & purification
QUALIFIER: chemistry
QUALIFIER: isolation & purification
QUALIFIER: chemistry
AUTHOR: Ismael León I
AUTHOR: Raúl G Enríquez RG
AUTHOR: David A Nieto DA
AUTHOR: Daniel Alonso D
AUTHOR: William F Reynolds WF
AUTHOR: Eduardo Aranda E
AUTHOR: Josué Villa J
AFFILIATION: Centro de Investigaciones Químicas, Universidad Autónoma del Estado de Morelos, Avenida Universidad 1001, Col. Chamilpa 62210 Cuernavaca, Morelos, México. ismaelr@ciq.uaem.mx
PUBTYPE: Journal Article
JOURNALTITLE: Journal of natural products.
COUNTRY: United States
TITLE: Pentasaccharide glycosides from the roots of Ipomoea murucoides.
PUBDATE: 20050801
Five pentasaccharide glycosides, murucins 1-5 (1-5), were isolated from the roots of the arboreal species Ipomoea murucoides, and their structures were elucidated by spectroscopic and chemical methods. Compounds 1-5 were evaluated for cytotoxicity against a small panel of cancer cell lines.


12. DOCID:29485 SCORE: 0.00139281242000713
DOCNO: 15270644
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: immunology
QUALIFIER: therapy
QUALIFIER: therapeutic use
AUTHOR: Benjamin Levy B
AUTHOR: Dennis Panicalli D
AUTHOR: John Marshall J
AFFILIATION: Lombardi Comprehensive Cancer Center, 3800 Reservoir Rd NW, Washington, DC 20007, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Expert review of vaccines.
COUNTRY: England
TITLE: TRICOM: enhanced vaccines as anticancer therapy.
PUBDATE: 20040801
Renewed interest in immune therapies for the treatment of cancer has sparked a number of different immune stimulation approaches. These include antibody based, dendritic cell-based and vaccine-based therapies. The poxvirus-based vaccines incorporating a TRIad of COstimulatory Molecules (TRICOM) will be reviewed here. Through stimulation of cancer-specific T-cell responses, researchers have demonstrated interesting clinical efficacy in addition to the high safety profile in clinical trials.


13. DOCID:30092 SCORE: 0.00139280328802752
DOCNO: 12654256
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: physiology
QUALIFIER: physiology
QUALIFIER: metabolism
QUALIFIER: physiology
AUTHOR: Boris Zhivotovsky B
AUTHOR: Sten Orrenius S
AFFILIATION: Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE-171 77 Stockholm, Sweden. boris.zhivotovsky@imm.ki.se
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Seminars in cancer biology.
COUNTRY: United States
TITLE: Defects in the apoptotic machinery of cancer cells: role in drug resistance.
PUBDATE: 20030401
The therapeutic goal in cancer treatment is to trigger tumor-selective cell death. Since many antineoplastic agents induce an apoptotic type of death in susceptible cells, it is likely that dysfunction of the apoptotic machinery might be an important determinant of resistance to anticancer drugs. Here we review known differences in the apoptotic machinery in cancer cells, and how this knowledge can be used to increase the efficiency of tumor treatment.


14. DOCID:30270 SCORE: 0.00139270780864481
DOCNO: 15354226
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Drug Design
QUALIFIER: chemistry
QUALIFIER: pharmacology
AUTHOR: Shuang Liu S
AFFILIATION: Department of Industrial and Physical Pharmacy, School of Pharmacy, Purdue University, 575 Stadium Mall Drive, West Lafayette, IN 47907, USA. lius@pharmacy.purdue.edu
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Chemical Society reviews.
COUNTRY: England
TITLE: The role of coordination chemistry in the development of target-specific radiopharmaceuticals.
PUBDATE: 20040901
There is a great current interest in developing target-specific radiopharmaceuticals for early detection of diseases and radiotherapy of cancers. This critical review will focus on the role of coordination chemistry in the development of target-specific radiopharmaceuticals. It will also discuss the recent development in technetium, copper, gallium, indium, yttrium and lanthanide chemistry, as well as analytical tools for quality control and characterization of radiolabeled small biomolecules (159 references).