0. DOCID:31675 SCORE: 0.00498863423188473
DOCNO: 14712781
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Software Design
QUALIFIER: therapeutic use
QUALIFIER: standards
QUALIFIER: drug therapy
QUALIFIER: complications
AUTHOR: Akira Shimada A
AUTHOR: Toshimichi Nakaho T
AUTHOR: Ken Yazaki K
AUTHOR: Takeshi Ohara T
AUTHOR: Nobutaka Kikuchi N
AUTHOR: Hidekazu Watanabe H
AUTHOR: Hiroyuki Yamanaka H
AUTHOR: Masahiko Takahashi M
AUTHOR: Makoto Yamamuro M
AFFILIATION: Tohoku University Hospital Palliative Care Center.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: Japan
TITLE: [The attempt to standardize treatment protocols for cancer-related hypercalcemia: developing a data-based flowchart]
PUBDATE: 20031201
We developed a flowchart for the treatment of cancer-related hypercalcemia based on the review of previous reports. The treatment protocols were standardized in each group of four different ranges of serum calcium concentration (< 12, 12-14, 14-16, < 16 mg/dl). In each Ca range, specific treatment was adjusted according to the clinical evaluation of symptoms and progression of illness of the patients.

1. DOCID:29708 SCORE: 0.00493339969768645
DOCNO: 15522339
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: chemistry
QUALIFIER: chemistry
AUTHOR: Chun Fang Zhou CF
AUTHOR: Jian Hua Zhu JH
AFFILIATION: Department of Chemistry, Nanjing University, Nanjing 210093, China.
PUBTYPE: Journal Article
JOURNALTITLE: Chemosphere.
COUNTRY: England
TITLE: Adsorption of nitrosamines in acidic solution by zeolites.
PUBDATE: 20050101
Adsorption of N-nitrosopyrrolidine (NPYR) by zeolite NaZSM-5, Hbeta and NaZSM-11 in acidic solution with pH of 1 was investigated. The NPYR uptake process obeyed the first-rate Lagegren kinetic equation describing adsorption, and the equilibrium data were fitted to the Langmuir or Freundlich adsorption equation. Zeolite ZSM-5, Hbeta and NaZSM-11 possessed a higher adsorption capacity than amorphous silica or ordered mesoporous siliceous SBA-15, implying their potential application for adsorption of nitrosamines in gastric juice to anti-cancer.

2. DOCID:29948 SCORE: 0.00475469315588801
DOCNO: 16205900
OWNER: NLM
STATUS: In-Process
AUTHOR: H Bonkhoff H
AFFILIATION: Praxis für Pathologie, Berlin. bonkhoff@prostapath.de
PUBTYPE: Journal Article
JOURNALTITLE: Der Pathologe.
COUNTRY: Germany
TITLE: [Prognostic factors in prostate cancer]
PUBDATE: 20051101
Since several therapeutic options are currently available for clinically organ-confined prostate cancer, morphological parameters have rapidly emerged as prognostic factors to stratify patients into different therapeutic modalities. In addition to the PSA value, pathologic stage, as defined by the TNM system, Gleason grade and the surgical margin status, other markers have prognostic implications. This includes the percent pattern 4/5 cancer, tumor volume, intraductal spread, large volume perineural invasion and molecular markers. This review discusses the methods of sampling and reporting in prostate pathology with an emphasis on well established and new prognostic factors.

3. DOCID:29607 SCORE: 0.00475468403159562
DOCNO: 16446258
OWNER: NLM
STATUS: In-Data-Review
AUTHOR: Thomas P Bradley TP
AUTHOR: Anne L Golden AL
AFFILIATION: Division of Oncology, North Shore University Hospital, New York University School of Medicine, 300 Community Drive, Manhasset, NY 11030, USA.
PUBTYPE: Journal Article
JOURNALTITLE: Clinics in occupational and environmental medicine.
COUNTRY: United States
TITLE: Tobacco and carcinogens in the workplace.
PUBDATE: 20050201
Workplace exposures to carcinogens long have been associated with cancers, and corrective measures to limit exposures have resulted in reductions in such cancers and improved worker health. Some exposures are currently of historical interest, and many current or past exposures are associated with conflicting evidence as to causality. We present a brief overview of the effects of exposure to asbestos, tobacco, and other known carcinogens.

4. DOCID:30147 SCORE: 0.00410577401683747
DOCNO: 16062011
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Soy Foods
DESCRIPTOR: Soybeans
QUALIFIER: prevention & control
QUALIFIER: prevention & control
AUTHOR: Kazuhiro Uenishi K
AFFILIATION: Kagawa Nutrition University, Japan.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Clinical calcium.
COUNTRY: Japan
TITLE: [Recommended soy and soy products intake to prevent bone fracture and osteoporosis]
PUBDATE: 20050801
Soy contains isoflavones, which are phytoestrogens, and its intake may help to prevent some diseases including menopausal disorder, osteoporosis, and breast cancer. Natto, a fermented soy product, is rich in vitamin K, which also contributes to bone health. In this report, we overviewed peer-reviewed papers showing relationship between soy product intake and risks of bone fracture and osteoporosis. It is suggested that that intake of soy products is not strongly enough to conclude but possible to be efficient in prevention of bone fracture and osteoporosis.

5. DOCID:31871 SCORE: 0.00372876178701704
DOCNO: 16277924
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: administration & dosage
QUALIFIER: administration & dosage
QUALIFIER: secondary
AUTHOR: Per Pfeiffer P
AUTHOR: Benny Vittrup Jensen BV
AFFILIATION: Odense Universitetshospital, Onkologisk Afdeling R.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Ugeskrift for laeger.
COUNTRY: Denmark
TITLE: [Drug therapy of patients with metastatic colorectal cancer]
PUBDATE: 20051101
In less than a decade, metastatic cancer in the colon or rectum has changed from being primarily a surgically palliated disease to one in which there have been increasing successes with combination chemotherapy and molecular targeted therapy. Without treatment, only half of the patients are alive after six months, and there are almost no survivors after two years. With modern therapy, about half of the patients are now alive after two years and the survival time continues to increase. Instead of being a more or less acute life-threatening disease, metastatic colorectal cancer may exist as a chronic condition for years.

6. DOCID:30540 SCORE: 0.00354820482063535
DOCNO: 12634621
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: adverse effects
QUALIFIER: chemically induced
QUALIFIER: adverse effects
QUALIFIER: adverse effects
AUTHOR: Maki Takabayashi M
AUTHOR: Rika Sakai R
AUTHOR: Hiroshi Sakamoto H
AUTHOR: Youichi Iemoto Y
AUTHOR: Heiwa Kanamori H
AUTHOR: Yoshiaki Inayama Y
AUTHOR: Yoshiaki Ishigatsubo Y
AFFILIATION: Department of Hematology/Immunology, Fujisawa City Hospital, Fujisawa, Japan. t-maki@swim.seaple.icc.ne.jp
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Anti-cancer drugs.
COUNTRY: England
TITLE: Merkel cell carcinoma developing after antithymocyte globulin and cyclosporine therapy for aplastic anemia.
PUBDATE: 20030301
We report a patient who developed Merkel cell carcinoma (MCC) after treatment with antithymocyte globulin and cyclosporine for aplastic anemia. The clinical course was progressive and poor prognosis. Although MCC is relatively rare in second cancers arising after immunosuppressive therapy, patients should be closely monitored for the development of this complication as well as other second malignancies.

7. DOCID:30581 SCORE: 0.00354820027445205
DOCNO: 16449925
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: J Margery J
AUTHOR: A Bonnichon A
AUTHOR: D Jeanbourquin D
AUTHOR: P Saint-Blancard P
AUTHOR: M Sane M
AUTHOR: J-M Dot JM
AUTHOR: F Grassin F
AUTHOR: F Vaylet F
AUTHOR: P L'Her P
AUTHOR: J Guigay J
AFFILIATION: Service des Maladies Respiratoires, Hôpital d'Instruction des Armées Percy, 101, avenue Henri-Barbusse, BP 406, 92140 Clamart. j.margery@wanadoo.fr
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Revue de pneumologie clinique.
COUNTRY: France
TITLE: [Pseudotumoral presentation of American pulmonary histioplasmosis]
PUBDATE: 20051201
In France, American pulmonary histoplasmosis is an imported deep mycosis, caused by inhalation of Histoplasma capsulatum. Clinical and radiological features of this exotic disease are multiple, simulating tuberculosis or cancer. We report two cases of American histoplasmosis with pseudo-tumoral form, in immunocompetent subjects working in Venezuela, with a multinodular pulmonary presentation.

8. DOCID:31771 SCORE: 0.00332669143696723
DOCNO: 15508459
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: blood
AUTHOR: Hiroshi Komagata H
AUTHOR: Shuichi Yoneda S
AFFILIATION: Division of Respiratory Disease, Saitama Cancer Center.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: Japan
TITLE: [Lung cancer]
PUBDATE: 20041001
Tumor markers are defined as substances which are produced by cancer cells or non-cancer cells reactive to cancer cells, and reflect the cancer status, such as its presence, characteristics, and volume. Clinically, many tumor markers are useful not only to assess the presence/absence of cancer, the primary site, histology, stage, and recurrence, but also to monitor the anti-cancer therapy. Tumor markers for lung cancer play only supporting roles because of their limited sensitivity and specificity, but they are clinically essential to daily medical oncology. This review addresses 6 important tumor markers for lung cancer, namely, CEA, SLX, CYFRA, SCC, ProGRP, and NSE.

9. DOCID:30102 SCORE: 0.00324920098263052
DOCNO: 12208173
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: physiopathology
QUALIFIER: therapy
AUTHOR: Q Kong Q
AUTHOR: J Sun J
AUTHOR: L D Kong LD
AFFILIATION: Cocid Corp, Denver, CO 80220, USA. kongq@cellbrain.org
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Medical hypotheses.
COUNTRY: Scotland
TITLE: Cell brain crystallization for cancer therapy.
PUBDATE: 20021001
Cancer remains one of the leading causes of death throughout the world. One of the important reasons why conventional treatments fail is the development of resistance to therapeutics. The dual effect concept and self-defense mechanism plus the threshold theory might in part explain the development of resistance, however, the primary cause is unclear. A novel theory, 'cell brain', where, selective crystallization of the 'brain' of a cell (comprising centrosome, centrioles and the connecting filaments) occurs, may be a potential alternate approach to cancer therapy.

10. DOCID:29291 SCORE: 0.0031761052707193
DOCNO: 15713393
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: chemistry
QUALIFIER: pharmacology
QUALIFIER: chemistry
QUALIFIER: pharmacology
QUALIFIER: antagonists & inhibitors
AUTHOR: Bin Chen B
AUTHOR: Pavel A Petukhov PA
AUTHOR: Mira Jung M
AUTHOR: Alfredo Velena A
AUTHOR: Elena Eliseeva E
AUTHOR: Anatoly Dritschilo A
AUTHOR: Alan P Kozikowski AP
AFFILIATION: Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, 833 South Wood Street, Chicago, IL 60612, USA.
PUBTYPE: Journal Article
JOURNALTITLE: Bioorganic & medicinal chemistry letters.
COUNTRY: England
TITLE: Chemistry and biology of mercaptoacetamides as novel histone deacetylase inhibitors.
PUBDATE: 20050301
A series of mercaptoacetamides were designed and synthesized as novel histone deacetylase inhibitors with the aid of modeling. Their ability to inhibit HDAC activity and their effects on cancer cell growth were investigated. Some compounds exhibit better HDAC inhibitory activity than SAHA.

11. DOCID:31160 SCORE: 0.00315972792130146
DOCNO: 16154827
OWNER: NLM
STATUS: In-Process
AUTHOR: Richard M Gore RM
AFFILIATION: Department of Radiology, Evanston Northwestern Healthcare, Northwestern University, 2650 Ridge Ave, Evanston, IL 60201, USA. rmgore1953@aol.com
PUBTYPE: Journal Article
JOURNALTITLE: Cancer imaging [electronic resource] : the official publication of the International Cancer Imaging Society.
COUNTRY: England
TITLE: Upper gastrointestinal tract tumours: diagnosis and staging strategies.
PUBDATE: 20050801
In patients with oesophageal and gastric cancer, accurate assessment of tumour extent within and beyond the gut wall and detection of lymph node and distant metastases are of paramount importance in planning the surgical approach, in deciding whether neo-adjuvant chemotherapy or radiation therapy is necessary, and in determining the risk of tumour recurrence and overall prognosis. The utility of MDCT, MR, endoscopic ultrasound, PET, PET/CT is discussed and recommendations for cost-effective imaging in these patients are presented.

12. DOCID:30918 SCORE: 0.00315972402121022
DOCNO: 16175178
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Neoplasm Metastasis
QUALIFIER: physiology
QUALIFIER: physiology
QUALIFIER: metabolism
QUALIFIER: physiology
AUTHOR: Rosa A Cardone RA
AUTHOR: Valeria Casavola V
AUTHOR: Stephan J Reshkin SJ
AFFILIATION: Department of General and Environmental Physiology, University of Bari, Via Amendola 165/A, 70126 Bari, Italy.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Nature reviews. Cancer.
COUNTRY: England
TITLE: The role of disturbed pH dynamics and the Na+/H+ exchanger in metastasis.
PUBDATE: 20051001
Recent research has highlighted the fundamental role of the tumour's extracellular metabolic microenvironment in malignant invasion. This microenvironment is acidified primarily by the tumour-cell Na(+)/H(+) exchanger NHE1 and the H(+)/lactate cotransporter, which are activated in cancer cells. NHE1 also regulates formation of invadopodia - cell structures that mediate tumour cell migration and invasion. How do these alterations of the metabolic microenvironment and cell invasiveness contribute to tumour formation and progression?

13. DOCID:30711 SCORE: 0.00314767793513549
DOCNO: 15823599
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
QUALIFIER: trends
QUALIFIER: trends
AUTHOR: Meisong Ding M
AUTHOR: Francis Newman F
AUTHOR: David Raben D
AFFILIATION: Department of Radiation Oncology, University of Colorado Health Science Center, Suite 1032, 1665 North Ursula Street, Aurora, CO 80010, USA. Meisong.ding@uchsc.edu
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Otolaryngologic clinics of North America.
COUNTRY: United States
TITLE: New radiation therapy techniques for the treatment of head and neck cancer.
PUBDATE: 20050401
This article reviews the most recent technology used in the treatment of head and neck cancer. It discusses brachytherapy, new ways to mix radionuclides for enhanced radiobiologic effects, and different fractionation schemes that have grown in clinical importance. Intensity-modulated radiotherapy has become a mainstay in head and neck cancer treatment, and the authors discuss several popular and emerging approaches. Patient immobilization and imaging are also discussed.

14. DOCID:31990 SCORE: 0.00303711132888334
DOCNO: 16095634
OWNER: NLM
STATUS: In-Data-Review
AUTHOR: Lynnette R Ferguson LR
AUTHOR: Giorgio Bronzetti G
AUTHOR: Silvio De Flora S
AFFILIATION: The University of Auckland, School of Medical Sciences, Faculty of Medical and Health Sciences, Discipline of Nutrition/ACSRC, Private Bag 92019, Auckland 1000, New Zealand.
PUBTYPE: Editorial
JOURNALTITLE: Mutation research.
COUNTRY: Netherlands
TITLE: Mechanistic approaches to chemoprevention of mutation and cancer.
PUBDATE: 20051201
This is the eighth special issue of 'Mutation Research' to focus on antimutagenesis and anticarcinogenesis. It covers a wide range of mechanisms from prevention of cancer initiation by antimutagens through to inhibition of tumour angiogenesis and selective estrogen receptor modulators. New screening methods and new biomarkers are also elucidated. There is increasing reason to believe that the long-term use of a combination of anticarcinogens, over an extended time span, may provide a realistic prospect of reducing the current burden of human cancers.