0. DOCID:23125 SCORE: 0.00405106671070477
DOCNO: 9186218
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Knee Joint
QUALIFIER: complications
QUALIFIER: etiology
QUALIFIER: complications
QUALIFIER: etiology
QUALIFIER: etiology
AUTHOR: H Aoshima H
AUTHOR: K Kushida K
AUTHOR: M Okada M
AUTHOR: Y Kageyama Y
AUTHOR: T Inoue T
AUTHOR: H Tomita H
AFFILIATION: Department of Orthopaedics, Hamamatsu University School of Medicine, Japan.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Clinical orthopaedics and related research.
COUNTRY: UNITED STATES
TITLE: Neuropathic arthropathy caused by paraneoplastic sensory neuropathy. A case report.
PUBDATE: 19970601
Neuropathic arthropathy of both knees after paraneoplastic sensory neuropathy developed in a 64-year-old woman. The patient was found to have small cell lung cancer 2 months after the onset of a sensory neuropathy that was diagnosed as paraneoplastic sensory neuropathy, a nonmetastatic neurologic complication in patients with malignancy. The onset of paraneoplastic sensory neuropathy was followed by the gradual onset of neuropathic arthropathy. This is the first well documented report on neuropathic arthropathy in a patient with paraneoplastic sensory neuropathy.

1. DOCID:22177 SCORE: 0.00402976152982515
DOCNO: 9555127
AUTHOR: H Galjaard H
AFFILIATION: Academisch Ziekenhuis Rotterdam-Dijkzigt, afd. Klinische Genetica, Rotterdam.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Nederlands tijdschrift voor geneeskunde.
COUNTRY: NETHERLANDS
TITLE: [Future developments in genetic research. I. Technological possibilities]
PUBDATE: 19971201
The attention in genetic research is shifting from the determination' of (rare) monogenic disorders to identification of genetic risk factors for important diseases at adult age. Mapping of all man's 80,000-100,000 genes will also provide more insight into the gene polymorphisms and mutations that are associated with various types of cancer, certain cardiovascular diseases, diabetes and neurodegenerative disorders, including Alzheimer dementia. Apart from new diagnostic possibilities, the DNA techniques create new prospects for the study of the pathogenesis of diseases and the devising of new strategies for treatment. Examples are familial hypercholesterolaemia, diabetes, breast cancer and colorectal carcinoma.

2. DOCID:21956 SCORE: 0.0039672339709477
DOCNO: 7661187
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: complications
QUALIFIER: microbiology
QUALIFIER: complications
AUTHOR: M Merle-Melet M
AUTHOR: F Mory F
AUTHOR: B Stempfel B
AUTHOR: P Maurer P
AUTHOR: D Régent D
AUTHOR: S Parent S
AUTHOR: J M Tortuyaux JM
AUTHOR: L Bresler L
AUTHOR: P Boissel P
AFFILIATION: Department of Infectious Diseases-Intensive Care Unit, Brabois University Hospital, Vandoeuvre, France.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: The American journal of gastroenterology.
COUNTRY: UNITED STATES
TITLE: Actinomyces naeslundii, acute cholecystitis, and carcinoma of the gallbladder.
PUBDATE: 19950901
This report describes the first case of biliary actinomycosis associated with an adenocarcinoma of the gallbladder. Actinomyces naeslundii was encountered as a pure isolate after a precise and careful identification. Although, in diagnosis, cancer and actinomycosis are often confused, the simultaneous occurrence of actinomycosis in cancer lesions can happen. This case illustrates the diagnostic challenge of actinomycosis.

3. DOCID:23968 SCORE: 0.00387802299272291
DOCNO: 7835803
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Ovarian Neoplasms
AUTHOR: R F Ozols RF
AFFILIATION: Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Gynecologic oncology.
COUNTRY: UNITED STATES
TITLE: Research directions in epithelial ovarian cancer.
PUBDATE: 19941201
Major improvements in survival from ovarian cancer will likely result from a combined effort in prevention, diagnosis, screening, and treatment. Oral contraceptives can decrease the risk of ovarian cancer in women with a family history of the disease. Screening currently is not routinely recommended and awaits further refinements in tumor markers and image techniques. Surgery and chemotherapy have been the cornerstones of treatment for most patients with ovarian cancer. Paclitaxel plus a platinum compound has now become a new standard chemotherapy regimen. However, numerous clinical questions need to be explored in prospectively randomized trials to determine how best to use this agent. Basic research in ovarian cancer will likely lead to the novel therapeutic targets and completely new approaches.

4. DOCID:21772 SCORE: 0.00368775498413673
DOCNO: 8004624
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Breast Neoplasms
DESCRIPTOR: Malpractice
DESCRIPTOR: Risk Management
AUTHOR: R J Brenner RJ
AFFILIATION: Department of Breast Imaging, John Wayne Cancer Institute, Los Angeles, California.
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Breast cancer evaluation. Medical-legal and risk management considerations for the clinician.
PUBDATE: 19940701
The legal consequences for physicians involved in the treatment of patients who are at risk for or have developed breast cancer are many. The law of negligence, which is concerned with departures from reasonable standards of conduct, govern most of the cases that come to legal attention. Several other torts or civil infractions, however, may be applicable to such practices. Lessons learned from both trial and appellate decisions rendered in this field offer some guidance to avoid untoward medical and legal consequences.

5. DOCID:22751 SCORE: 0.00325210212723798
DOCNO: 7851141
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: methods
AUTHOR: U Engel U
AUTHOR: A Kucharski A
AUTHOR: C Zornig C
AFFILIATION: I. Chirurgische Abteilung, Allgemeines Krankenhaus Hamburg-Harburg.
PUBTYPE: Journal Article
JOURNALTITLE: Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen.
COUNTRY: GERMANY
TITLE: [Limited radical approach in differentiated thyroid gland cancers. A prospective study of 107 patients]
PUBDATE: 19941201
From 1979 until 1987 a prospective study about limited radical therapy of 107 patients with differentiated cancer of the thyroid was performed. Nearly all of the tumors were occult papillary or encapsulated papillary and follicular carcinomas. The thyroid was not completely resected. Postoperative therapy consisted in TSH-suppression. After a follow-up of 7.5 (5-12) years one patient had died because of the tumor disease. Four patients had to be reoperated for lymph node metastases and then stayed free of disease as all other patients.

6. DOCID:22769 SCORE: 0.00325209975401083
DOCNO: 7944497
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: K Hirama K
AUTHOR: Y Mikami Y
AUTHOR: T Nishi T
AUTHOR: H Suzuki H
AUTHOR: Y Sugiyama Y
AUTHOR: M Konn M
AFFILIATION: Dept. of Surgery, Hirosaki University School of Medicine.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [A case of gastric cancer with Borrmann type 4 responding to 5-FU-MMC combined chemotherapy]
PUBDATE: 19941001
A 70-year-old man with advanced Borrmann type 4 was preoperatively treated with 5-FU-MMC combined chemotherapy. The primary tumor including a palpable mass in the abdomen was diminished, and eventually the patient underwent curative resection. This preoperative regimen for advanced Borrmann type 4 gastric cancer might be recommended from the standpoint of less adverse effects of chemotherapy. The patient died suddenly of cardiac infarction in 9 months without recurrent signs.

7. DOCID:23949 SCORE: 0.00318438177823973
DOCNO: 7480625
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Astronauts
DESCRIPTOR: Radiation Protection
DESCRIPTOR: Space Flight
AUTHOR: E A Blakely EA
AUTHOR: R J Fry RJ
AFFILIATION: Life Sciences Division, Lawrence Berkeley Laboratory, Berkeley, CA 94720, USA.
PUBTYPE: Journal Article
JOURNALTITLE: Radiation and environmental biophysics.
COUNTRY: GERMANY
TITLE: Radiation protection in space.
PUBDATE: 19950801
The challenge for planning radiation protection in space is to estimate the risk of events of low probability after low levels of irradiation. This work has revealed many gaps in our knowledge that require further study. Despite investigations of several irradiated populations, the atomic-bomb survivors remain the primary basis for estimating the risk of ionizing radiation. Compared with previous estimates, two new independent evaluations of available information indicate a significantly greater risk of stochastic effects of radiation (cancer and genetic effects) by about a factor of three for radiation workers, including space travelers. This paper presents a brief historical perspective of the international effort to assure radiation protection in space.

8. DOCID:21051 SCORE: 0.00316877189059502
DOCNO: 7701001
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pharmacology
QUALIFIER: chemistry
AUTHOR: D B Wickramaratne DB
AUTHOR: W Mar W
AUTHOR: H Chai H
AUTHOR: J J Castillo JJ
AUTHOR: N R Farnsworth NR
AUTHOR: D D Soejarto DD
AUTHOR: G A Cordell GA
AUTHOR: J M Pezzuto JM
AUTHOR: A D Kinghorn AD
PUBTYPE: Letter
JOURNALTITLE: Planta medica.
COUNTRY: GERMANY
TITLE: Cytotoxic constituents of Bursera permollis.
PUBDATE: 19950201
Four cytotoxic lignans were isolated from the stem bark of Bursera permollis (Burseraceae), namely, deoxypodophyllotoxin (1), beta-peltatin methyl ether (2), picro-beta-peltatin methyl ether (3), and dehydro-beta-peltatin methyl ether (4). Also isolated was the inactive lignan, nemerosin (5). Compounds 1 and 2 were potently cytotoxic when evaluated against a panel of human cancer cell lines.

9. DOCID:21941 SCORE: 0.00314768035519341
DOCNO: 8691628
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Immunoconjugates
DESCRIPTOR: Tumor Markers, Biological
QUALIFIER: therapeutic use
QUALIFIER: therapy
QUALIFIER: methods
AUTHOR: T Yamaguchi T
AUTHOR: T Takahashi T
AUTHOR: K Kitamura K
AUTHOR: E Otsuji E
AFFILIATION: First Department of Surgery, Kyoto Prefectural University of Medicine.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Nippon rinsho. Japanese journal of clinical medicine.
COUNTRY: JAPAN
TITLE: [Application of tumor marker for immunotargeting therapy of cancer]
PUBDATE: 19960601
For many years, attempts have been made to utilize the monoclonal antibody against tumor markers for diagnostic purposes. On the other hand, studies with various form of immunoconjugate have demonstrated some therapeutic promise. In this paper, the ideal tumor marker for immunotargeting therapy will be discussed. Results of clinical trials of radioimmunoconjugates, immunotoxin and chemoimmunoconjugates will be reviewed and prospects of these new approaches for the treatment of cancer patients will be presented.

10. DOCID:23904 SCORE: 0.00309246830358404
DOCNO: 9415244
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: etiology
QUALIFIER: complications
QUALIFIER: etiology
QUALIFIER: etiology
QUALIFIER: etiology
QUALIFIER: etiology
AUTHOR: M D Alconchel MD
AUTHOR: C Olivares C
AUTHOR: R Alvarez R
AFFILIATION: Hospital Miguel Servet, P Isabel La Católica 1, Zaragoza, Spain.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The British journal of dermatology.
COUNTRY: ENGLAND
TITLE: Squamous cell carcinoma, malignant melanoma and malignant fibrous histiocytoma arising in burn scars.
PUBDATE: 19971101
The most common cancer arising from an old burn scar is squamous cell carcinoma, while malignant melanoma is rare. There are only four reports in the literature on the combination of the more common tumour with a malignant melanoma and only two cases of malignant fibrous histiocytoma alone. This paper reports the first occurrence of the combination of all three types of cancer in burn scars of the same patient. The factors that promote malignant transformation, such as immunological factors and karyotype, are discussed. We also performed an immunohistochemical study using anti-p53 antibodies.

11. DOCID:20452 SCORE: 0.00301142433490985
DOCNO: 9138330
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: secondary
QUALIFIER: secondary
QUALIFIER: pathology
AUTHOR: J Aubert J
AUTHOR: J Irani J
AUTHOR: P Saint-Blancat P
AFFILIATION: Service d'Urologie, CHU de Poitiers.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Chirurgie; mémoires de l'Académie de chirurgie.
COUNTRY: FRANCE
TITLE: [Orbital metastasis of prostatic cancer. Clinical and therapeutic aspects. Apropos of a case (clinical case)]
PUBDATE: 19970101
A metastasis to the left orbit revealed cancer of the prostate in a 60-year-old man. Such localizations are rare compared with the frequency of bone metastasis in cancer of the prostate. Diagnostic methods are discussed together with the urgent required to save the eye.

12. DOCID:23666 SCORE: 0.00290414130822534
DOCNO: 7793990
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Genes, ras
QUALIFIER: genetics
AUTHOR: Y Yuasa Y
AFFILIATION: Dept. of Hygiene and Oncology, Tokyo Medical and Dental University School of Medicine, Japan.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [Gene diagnosis of cancer]
PUBDATE: 19950601
Recently, many DNA alterations have been reported in most of cancers. Now, gene diagnosis of cancers becomes a hot topic. There are at least three kinds of cancer-related genes, oncogenes, tumor suppressor genes and DNA mismatch repair genes. In hereditary tumors, gene diagnosis is particularly important, because it is possible to find predisposing individuals even before the appearance of cancers. Of course, gene diagnosis is also very useful for nonhereditary tumors. A very small numbers of cancer cells in blood, sputum, urine and stool can be detected by the highly sensitive PCR (polymerase chain reaction) technique. Prognosis may also be predicted from specific gene alterations in cancers.

13. DOCID:21887 SCORE: 0.0026835298563908
DOCNO: 7712829
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Scalp
QUALIFIER: secondary
QUALIFIER: pathology
QUALIFIER: secondary
AUTHOR: M Lee M
AUTHOR: E E Duke EE
AUTHOR: J Munoz J
AUTHOR: L Holaday L
AFFILIATION: Department of Medicine, University of Texas Health Science Center, San Antonio 78284-7878, USA.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Cutis; cutaneous medicine for the practitioner.
COUNTRY: UNITED STATES
TITLE: Colorectal cancer presenting with a cutaneous metastatic lesion on the scalp.
PUBDATE: 19950101
Cutaneous metastases occur rarely with colorectal adenocarcinoma, accounting for approximately 5 percent of all cutaneous metastases. Cutaneous metastases from colonic cancer are most often located on the abdominal skin. The case we describe here is unusual because colorectal adenocarcinoma rarely metastasizes to the scalp. A review of the English language literature revealed only six reported cases of cutaneous metastases from a colonic adenocarcinoma to the scalp.

14. DOCID:21913 SCORE: 0.00268352950154855
DOCNO: 8686072
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: injuries
QUALIFIER: surgery
AUTHOR: M Rolff M
AUTHOR: T Bang T
AUTHOR: E Bostofte E
AUTHOR: J T Andersen JT
AFFILIATION: Gynaekologisk-obstetrisk afdeling, Hvidovre Hospital.
PUBTYPE: Journal Article
JOURNALTITLE: Ugeskrift for laeger.
COUNTRY: DENMARK
TITLE: [Lesions of the ureter in radical hysterectomy for cervical cancer]
PUBDATE: 19960601
Eight ureter lesions of the ureter occurred among 100 consecutive patients undergoing radical hysterectomy for cancer of the uterine cervix. The management of this problem is discussed, and treatment guidelines for the most commonly seen lesions are proposed. It is concluded that a more liberal use of ureteric stents or catheters should be considered so as to reduce the number of ureteric lesions occurring in connection with radical hysterectomy. Urological assistance should be sought for urological lesions recognized during or after such operations.