0. DOCID:14996 SCORE: 0.0057800739712571
DOCNO: 2722056
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: methods
QUALIFIER: adverse effects
QUALIFIER: chemically induced
QUALIFIER: drug therapy
AUTHOR: E Kujansuu E
AUTHOR: T Rahko T
AUTHOR: R Punnonen R
AUTHOR: P Karma P
AFFILIATION: Department of Obstetrics and Gynecology, Tampere University Hospital, Finland.
PUBTYPE: Journal Article
JOURNALTITLE: Gynecologic oncology.
COUNTRY: UNITED STATES
TITLE: Evaluation of the hearing loss associated with cis-platinum treatment by high-frequency audiometry.
PUBDATE: 19890601
The effect of cis-platinum treatment on the hearing of 23 ovarian cancer patients was evaluated using standard and high-frequency audiometry. Twenty-two percent of the patients developed a hearing loss of at least 15 db, 13% in the range 125-8000 Hz and 9% only in the high-frequency area above 8 kHz. However, due to the high-frequency hearing loss (presbyacusis) in older patients high-frequency audiometry was often unobtainable. Hearing screening using standard pure-tone audiometry is recommended for cis-platinum patients as a routine procedure.


1. DOCID:15834 SCORE: 0.00450785479667393
DOCNO: 3811093
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: W W Bonney WW
AUTHOR: R A Robinson RA
AUTHOR: P A Lachenbruch PA
AUTHOR: D A Culp DA
PUBTYPE: Journal Article
JOURNALTITLE: Urology.
COUNTRY: UNITED STATES
TITLE: Yield of cancer tissue from prostatic needle biopsy.
PUBDATE: 19870201
This study concerns the quality of human prostatic cancer needle biopsy specimens for routine diagnosis and for bioassay. We examined routine hematoxylin and eosin-stained microscopic sections from 20 prostatic cancer patients, 159 needle cores in all, 71 positive for tumor. Linear core measurements were made with a calibrated ocular micrometer, each segment counted positive if it contained any tumor. Among all subjects there were 35.5 cm of tumor-bearing core length, 26 per cent of the total core length but 60 per cent of the length if completely negative cores were excluded. From these data we calculate a 91 per cent probability of detecting any cancer present if at least 4 cores are taken.


2. DOCID:15246 SCORE: 0.00408948025897898
DOCNO: 2560508
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: epidemiology
QUALIFIER: epidemiology
AUTHOR: M Melato M
AUTHOR: P Peruzzo P
AUTHOR: L Laurino L
AUTHOR: M Valente M
AUTHOR: A Tussoni A
PUBTYPE: Journal Article
JOURNALTITLE: Klinicheskaia meditsina.
COUNTRY: USSR
TITLE: [Cancer of the liver (analysis of autopsy data)]
PUBDATE: 19891101
The findings at 26.879 autopsies, that is 70% of all the deaths registered in the Province of Trieste, obtained at the Institute of Pathologic Anatomy and Histology of Trieste from 1976 to 1985 were studied. Liver cancer showed in the Province the World Standardized Incidence Rate (WR) of 1.87 (females) and 12.78 (males), one of the highest ever observed in nonendemic areas. In view of close association between cancer of the liver and cirrhosis (88%), the authors studied the most important etiological factors of cirrhosis in the region, i.e. hepatitis B and alcohol abuse. Some effective measures are suggested to decrease the incidence of cirrhosis and eventually cancer of the liver.


3. DOCID:15695 SCORE: 0.0038536368654723
DOCNO: 2926989
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: etiology
QUALIFIER: complications
QUALIFIER: etiology
QUALIFIER: etiology
QUALIFIER: etiology
AUTHOR: T Kishimoto T
AUTHOR: K Okada K
AUTHOR: Y Nagake Y
AUTHOR: K Doi K
AUTHOR: Y Takusagawa Y
AUTHOR: T Ono T
AUTHOR: F Shimamoto F
AFFILIATION: Dept. of Clinical Investigation, Kure Kyosai Hospital.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [A case of asbestosis complicated with double cancer of the stomach and colon]
PUBDATE: 19890201
A case of a double cancer, a stomach and a colon cancer, in a 84-year-old man is reported. The patient had an occupational history of asbestos exposure while working at two shipyards. His chest X-ray revealed typical, pleural plaque with calcification. Further, a significant number of asbestos bodies in his autopsied lung tissue was detected. In spite of failure to detect asbestos bodies in the stomach and the colon, our findings suggest that these two cancers may have been induced by asbestos exposure.


4. DOCID:15293 SCORE: 0.00373651219583298
DOCNO: 3493732
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
QUALIFIER: methods
QUALIFIER: therapeutic use
QUALIFIER: transplantation
QUALIFIER: therapy
AUTHOR: Y Kimoto Y
AUTHOR: Y Tanji Y
AUTHOR: T Tanaka T
AUTHOR: T Taguchi T
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [Adoptive immunotherapy of malignant diseases with LAK cells]
PUBDATE: 19870301
Peripheral blood lymphocytes obtained from patients by leukapheresis were cultured in RPMI 1640 containing human plasma and interleukin 2. The morphology, phenotypes and cytotoxicity of induced LAK cells were studied. Lymphoblastoid cells mainly proliferated were OKIa1+ cells and were thought to be LAK cells. Maximal cytotoxicity was obtained after two weeks of incubation. IL-2 enhanced the cytotoxicity of LAK cells. Autologous LAK cells induced by two weeks of incubation were injected into patients. One case of pulmonary metastases of breast cancer showed reduction and two lesions showed partial regression. Also, no new lesions appeared in the lungs of a patient with alveolar soft-part sarcoma.


5. DOCID:13216 SCORE: 0.00370540135439334
DOCNO: 2798213
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
AUTHOR: A Rasiński A
AUTHOR: D Celińska-Cedro D
AUTHOR: H Rondio H
PUBTYPE: Journal Article
JOURNALTITLE: Polski tygodnik lekarski (Warsaw, Poland : 1960)
COUNTRY: POLAND
TITLE: [Barrett esophagus]
PUBDATE: 19890101
An analysis of the clinical picture of Barrett's esophagus in 18 children is presented. This group of patients have been distinguished out of 114 children with chronic gastroesophageal reflux on the base of anatomopathological examinations. Clinical course and efficiency of the diagnostic examinations depend on the degree of esophagitis. They are slightly characteristic in children with minimal lesions. Long-term follow up - necessary due to the risk of cancer - have shown that there is possibility of recovery in cases of minimal advancement and short duration of the disease.


6. DOCID:14806 SCORE: 0.00359308956979176
DOCNO: 3019510
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: complications
QUALIFIER: complications
QUALIFIER: etiology
AUTHOR: T Nakano T
AUTHOR: J Fujii J
AUTHOR: S Tamura S
AUTHOR: T Hada T
AUTHOR: K Higashino K
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Thrombocytosis in patients with malignant pleural mesothelioma.
PUBDATE: 19861001
Thrombocytosis above 40.0 X 10(4)/mm3 occurred in five of six (83%) patients with malignant mesothelioma. In contrast, the incidence of thrombocytosis was 7.5% in patients with lung adenocarcinoma, 12.5% in squamous cell carcinoma, 5.1% in small cell carcinoma, and 41.7% in large cell carcinoma, respectively. The platelet count in large cell carcinoma was significantly higher than that in other cell types of lung cancer; however, the platelet count in malignant mesothelioma was much higher than that in large cell carcinoma. These results show that the incidence of thrombocytosis seems to be high in malignant mesothelioma, although the mechanism is thus far unknown.


7. DOCID:14703 SCORE: 0.00351630747204905
DOCNO: 3172512
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Quality of Life
QUALIFIER: rehabilitation
AUTHOR: I Ono I
AUTHOR: T Kaneko T
AUTHOR: S Ebihara S
AUTHOR: H Saitou H
AUTHOR: T Yoshizumi T
AUTHOR: W Ohyama W
AUTHOR: M Saikawa M
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [Quality of life in treated head and neck cancer patients]
PUBDATE: 19880801
Sixty-Seven patients with head and neck cancer have been studied with respect to their quality of life after their treatment. The Grogono Woodgate index was used to evaluate their quality of life, the quality of life of patients treated for laryngeal cancer was excellent, even if they underwent total laryngectomy. On the contrary, however, patients who had hypopharyngeal cancer and had undergone a pharyngolaryngoesophagectomy had the lowest indices. As for patients with an oral cancer, their indices were high if the cancer was being controlled by radiotherapy.


8. DOCID:12865 SCORE: 0.00340689326806354
DOCNO: 3016965
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: W Bürgler W
AUTHOR: P Jaeger P
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Der Urologe. Ausg. A.
COUNTRY: GERMANY, WEST
TITLE: [Diagnostic parameters and their value in testicular tumors]
PUBDATE: 19860501
Diagnosis of the retroperitoneum to deliniate metastases of nonseminomatous germinal cell testicular cancer, when combined with Computer tomography, Sonography and Lymphography has a high specificity. With regard to treatment, the differentiation between stage I and stage II is very important. In the so called high risk groups (MTU-Tumour, T3-Primary tumour) a stage I can actually be a stage II. Computer Tomography of the thorax should be made to deliniate a stage III tumour.


9. DOCID:13781 SCORE: 0.00330659556992182
DOCNO: 2649707
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Mass Screening
QUALIFIER: prevention & control
AUTHOR: A Oshima A
AFFILIATION: 1st Dept. of Cancer Screening, Osaka Cancer Prevention and Detection Center.
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [Evaluation of cancer screening from the epidemiologic point of view]
PUBDATE: 19890101
In Japan four kinds of cancer screening programs, namely screening programs for stomach cancer, uterine cancer, breast cancer and lung cancer, have been conducted under the Health and Medical Law for the Aged People. Now, however, it is demonstrated that cancer screening is not always effective in reducing cancer mortality. Therefore, new cancer screening programs, including colo-rectal cancer screening, should be evaluated by a well-designed study, like randomized controlled trial, before implementation as a public health policy.


10. DOCID:15654 SCORE: 0.00307425692463668
DOCNO: 3489312
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Neuroleptanalgesia
QUALIFIER: adverse effects
QUALIFIER: etiology
QUALIFIER: adverse effects
QUALIFIER: surgery
QUALIFIER: etiology
QUALIFIER: etiology
AUTHOR: V P Gadalov VP
AUTHOR: P P Firsova PP
AUTHOR: R P Ovechkina RP
PUBTYPE: Journal Article
JOURNALTITLE: Vestnik khirurgii imeni I. I. Grekova.
COUNTRY: USSR
TITLE: [Role of anesthesia in the development of postoperative infectious complications in thoracic oncological surgery]
PUBDATE: 19860501
Clinical analysis of incidence and degree of postoperative infectious complications was made in 140 patients subjected to operations on the lungs for cancer. The analysis has shown that in the group of patients operated upon under conditions of combined halothane anesthesia, the incidence and degree of postoperative infectious complications (suppuration of wounds, pneumonia in the other lung, empyema of the pleura) were considerably higher than in the group of patients operated on under conditions of neuroleptoanesthesia. The incidence of infectious complications was also higher in patients operated upon after preoperative irradiation. Mechanisms of immunosuppressive effects of general halothane anesthesia are discussed.


11. DOCID:15235 SCORE: 0.00297669364304298
DOCNO: 3718601
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: blood
AUTHOR: H Oelschläger H
AUTHOR: D Rothley D
AUTHOR: U Dunzendorfer U
PUBTYPE: Journal Article
JOURNALTITLE: Arzneimittel-Forschung.
COUNTRY: GERMANY, WEST
TITLE: [Direct determination of diethylstilbestrol and its monoconjugates in plasma]
PUBDATE: 19860401
Direct Determination of Diethylstilbestrol and its Monoconjugates in Plasma After "homogeneous ion pair extraction" with CH3OH from plasma of patients suffering from metastatic prostate cancer and subsequent partitioning on a C18-phase diethylstilbestrol (E-DES) and its monoconjugates (glucuronide, sulfate) as well as its glucuronide-sulfate conjugate may be detected quantitatively by HPLC/UV (236 nm) or HPLC/ED (+1.0 V). Working electrode is a special home-made carbon paste electrode. The range of detection is in the low ng range (2-5 ng/ml plasma); standard deviation is less than 5%. It is the first time that plasma levels of these metabolites of fosfestrol (Honvan) could be measured directly without prior hydrolysis.


12. DOCID:14730 SCORE: 0.00297111215164208
DOCNO: 3770991
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: metabolism
QUALIFIER: etiology
QUALIFIER: blood
AUTHOR: J W Moore JW
AUTHOR: G M Clark GM
AUTHOR: S A Hoare SA
AUTHOR: R R Millis RR
AUTHOR: J L Hayward JL
AUTHOR: M K Quinlan MK
AUTHOR: D Y Wang DY
AUTHOR: R D Bulbrook RD
PUBTYPE: Journal Article
JOURNALTITLE: International journal of cancer. Journal international du cancer.
COUNTRY: UNITED STATES
TITLE: Binding of oestradiol to blood proteins and aetiology of breast cancer.
PUBDATE: 19861101
A prospective study of 5,000 women has shown that, compared to controls, those who subsequently developed breast cancer had a higher proportion of their blood oestradiol in the non-protein-bound and albumin-bound fractions (the bio-available fraction) and a lower proportion in the sex-hormone-bound fraction. The increased proportion of bio-available oestradiol was partly due to a lower concentration of sex-hormone-binding globulin. Weight was excluded as a confounding factor.


13. DOCID:13834 SCORE: 0.00283743383940154
DOCNO: 2753725
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: methods
QUALIFIER: pathology
AUTHOR: U Laffer U
AUTHOR: M Müller M
AUTHOR: F Harder F
PUBTYPE: Journal Article
JOURNALTITLE: Helvetica chirurgica acta.
COUNTRY: SWITZERLAND
TITLE: [Indications-related and technical errors and their consequences in breast saving treatment]
PUBDATE: 19890401
Conservative treatment becomes an established procedure for small breast cancer worldwide. Randomized and non-randomized studies have shown equal prognostic results compared with the more radical operative treatment. This large-scale therapy only can be worthwhile, if the cosmetic results are better than breast reconstruction after mastectomy. Therefore a rigorous indication, a standardized technical procedure and a well-functioning team of interdisciplinary cooperation is required. Out of 500 conservatively treated patients we controlled a random sample of 134 relative to the cosmetic result. The results were related to our standard technique.


14. DOCID:15900 SCORE: 0.00262405227901225
DOCNO: 3320232
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Mass Screening
DESCRIPTOR: Occult Blood
QUALIFIER: epidemiology
QUALIFIER: epidemiology
AUTHOR: J Windeler J
AUTHOR: J Köbberling J
AFFILIATION: Department of Medicine, Ferdinand-Sauerbruch Klinik, Wuppertal, Federal Republic of Germany.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: International journal of colorectal disease.
COUNTRY: GERMANY, WEST
TITLE: Colorectal carcinoma and Haemoccult. A study of its value in mass screening using meta-analysis.
PUBDATE: 19871101
Meta-analysis has been performed on the world literature relating to Haemoccult screening for colorectal cancer. The analysis indicated a sensitivity of about 50%, specificity of about 97%, positive predictive value of 4.3% and negative predictive value of 99.85%. These figures assume a prevalence of colorectal cancer in the population of 0.3%. A model calculation using these figures together with some additional realistic assumptions suggests no reduction in mortality compared to an unscreened population. It is concluded that many questions about faecal occult blood screening remain and that uncontrolled mass population screening is not justified at this stage.