0. DOCID:18693 SCORE: 0.00327966653063595
DOCNO: 1511020
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Pleural Effusion, Malignant
AUTHOR: M Tattersall M
AFFILIATION: University of Sydney, New South Wales, Australia.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Current opinion in oncology.
COUNTRY: UNITED STATES
TITLE: Pleural effusions.
PUBDATE: 19920801
Pleural effusions are a common development in patients with cancer. The optimal means of control are not defined, but systemic treatment is often effective in patients with drug-sensitive tumors. Local treatments advocated in the management of malignant pleural effusions differ in the means of drainage, the length of time pleural tubes are left in situ, and the type of intrapleural therapy administered. Randomized trials published in the past few months have suggested that bleomycin sulfate may be superior to tetracycline as a sclerosant and that mitoxantrone does not add to control of effusions compared with large-bore pleural tube alone placed at time of thoracoscopy.

1. DOCID:18644 SCORE: 0.00327964136732685
DOCNO: 1608614
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: enzymology
AUTHOR: I Romics I
AFFILIATION: St. Agnes Hospital, Urológiai Osztály, Bocholt.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Orvosi hetilap.
COUNTRY: HUNGARY
TITLE: [Comparison of the diagnostic value of different tumor markers in prostatic cancer patients]
PUBDATE: 19920601
The author compared the tumour markers of hundred virginell prostatic cancer patients. There were investigated the activity of prostatic acid phosphatase (SP) and its isoenzyme (SPP) by enzymatic method (PAP) as well. The concentration of prostatic specific antigen (PSA) was determined too. The sensibility of markers are growing on the row, SP, SPP, PAP, PSA. Summarising the results, the determination of PAP together with PSA seems to be not necessary. Because of the low price of SP, SPP their determinations is indicated in selected cases. Regarding of costs-benefit the author advises selected investigations in different stage and in different indications.

2. DOCID:23696 SCORE: 0.00321904192051119
DOCNO: 7905152
AUTHOR: I Mittra I
AFFILIATION: Department of Surgery, Tata Memorial Hospital, Bombay, India.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Lancet.
COUNTRY: ENGLAND
TITLE: Breast screening: the case for physical examination without mammography.
PUBDATE: 19940201
Many studies have shown that screening for breast cancer can reduce mortality from the disease. Mammography has come to be regarded as the screening method of choice, but evidence suggests that physical examination (PE) is at least as effective in reducing mortality. Mammography detects many non-infiltrating and small, non-palpable tumours, but we do not know whether these would ever cause symptoms or threaten the woman's life. It is doubtful whether the time gained by early mammographic detection confers any survival benefit over PE detection. PE has substantial advantages over mammography in terms of human and economic costs. The question we should be asking is not how to refine mammographic screening but whether we need it at all.

3. DOCID:23603 SCORE: 0.0032189919770037
DOCNO: 9313857
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Plants, Medicinal
QUALIFIER: isolation & purification
QUALIFIER: chemistry
QUALIFIER: isolation & purification
AUTHOR: J A Beutler JA
AUTHOR: Y Kashman Y
AUTHOR: L K Pannell LK
AUTHOR: J H Cardellina JH
AUTHOR: M R Alexander MR
AUTHOR: M S Balaschak MS
AUTHOR: T R Prather TR
AUTHOR: R H Shoemaker RH
AUTHOR: M R Boyd MR
AFFILIATION: Laboratory of Drug Discovery Research & Development, National Cancer Institute, Frederick, MD 21702-1201, USA.
PUBTYPE: Journal Article
JOURNALTITLE: Bioorganic & medicinal chemistry.
COUNTRY: ENGLAND
TITLE: Isolation and characterization of novel cytotoxic saponins from Archidendron ellipticum.
PUBDATE: 19970801
A series of new ester saponins, elliptosides A-J, has been isolated from the tropical plant Archidendron ellipticum (Leguminosae). These saponins were particularly cytotoxic to certain renal and melanoma cancer cell lines in the NCI's 60-cell line human tumor screen. The structures of elliptosides A, E, and F were elucidated by spectroscopic and chemical means. Elliptoside A showed in vivo antitumor activity against the LOX melanoma cell line.

4. DOCID:19937 SCORE: 0.00316670597381359
DOCNO: 1744461
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: blood
QUALIFIER: blood
QUALIFIER: chemically induced
AUTHOR: Y Matsuura Y
AUTHOR: M Shinohara M
AUTHOR: M Kashimura M
AUTHOR: S Baba S
AUTHOR: H Otsuka H
AUTHOR: Y Okamura Y
AFFILIATION: Department of Obstetrics and Gynecology, University of Occupational and Environmental Health, Fukuoka.
PUBTYPE: Journal Article
JOURNALTITLE: Nippon Sanka Fujinka Gakkai zasshi.
COUNTRY: JAPAN
TITLE: [Disorder of serum electrolytes following CAP therapy]
PUBDATE: 19911201
Combination chemotherapy with Cyclophosphamide, Adriamycin and Cisplatin (CAP) is one of the most effective chemotherapies for ovarian cancer. Severe vomiting induced by this treatment may cause a disorder of the serum electrolytes. Severe hyponatremia was observed in one patient who complained of convulsions and unconsciousness. Accordingly we studied the disorder of serum electrolytes in 158 courses of CAP treatment (44 patients) during the five years from 1984 to 1988. The serum electrolytes were influenced by the amount of vomiting in this study. Consequently frequent examination of serum electrolytes is necessary during this treatment.

5. DOCID:19911 SCORE: 0.00316669162135771
DOCNO: 2022508
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: instrumentation
QUALIFIER: therapeutic use
QUALIFIER: radiotherapy
AUTHOR: K Wallner K
AUTHOR: S T Chiu-Tsao ST
AUTHOR: J Roy J
AUTHOR: M Rosenstein M
AUTHOR: H Smith H
AUTHOR: Z Fuks Z
AFFILIATION: Memorial Sloan-Kettering Cancer Center, New York, NY 10021.
PUBTYPE: Journal Article
JOURNALTITLE: International journal of radiation oncology, biology, physics.
COUNTRY: UNITED STATES
TITLE: A new device to stabilize templates for transperineal I-125 implants.
PUBDATE: 19910501
Transperineal Iodine-125 implants of the prostate are currently being performed at Memorial Sloan-Kettering Cancer Center with CT-based treatment planning and transrectal ultrasound for verification of proper needle placement in the prostate at the time of implantation. An adjustable device, the WIPI, has been designed to stabilize the perineal template and rectal obturator during planning and implementation of the procedure. The device is simple to use and is compatible with CT scanning, transrectal ultrasound, and the Mick applicator. Its design and key functional features are described here.

6. DOCID:19120 SCORE: 0.00316071856437451
DOCNO: 1381451
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
AUTHOR: M Hozumi M
AFFILIATION: Saitama Cancer Center Research Institute.
PUBTYPE: Journal Article
JOURNALTITLE: Nippon rinsho. Japanese journal of clinical medicine.
COUNTRY: JAPAN
TITLE: [Differentiation therapy of hematologic malignancies: principles, current status and perspectives]
PUBDATE: 19920601
There is increasing evidence that various tumor cells can be induced by differentiation inducers including biological response modifiers, synthetic chemicals and conventional anticancer drugs to differentiate terminally both in vitro and in vivo into cells with normal characteristics. The differentiated cells lose their abilities for proliferation and transplantation in animals. Furthermore, survival times of the animals inoculated with various tumors were found to prolong by administration with the differentiation inducers. These basic findings suggest that induction of terminal tumor cell differentiation is another strategy for cancer therapy: differentiation therapy of cancer. Principles, current status and perspectives of the differentiation therapy of leukemia are reviewed in this article.

7. DOCID:19742 SCORE: 0.0031044905841452
DOCNO: 1729088
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: adverse effects
QUALIFIER: chemically induced
QUALIFIER: drug therapy
QUALIFIER: blood
AUTHOR: S Hayashi S
AUTHOR: H Ogino H
AUTHOR: K Ogata K
AUTHOR: K Yagawa K
AFFILIATION: Research Institute for Diseases of the Chest, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Chest.
COUNTRY: UNITED STATES
TITLE: Hypercoagulopathy induced by chemotherapy in a patient with lung cancer. A possible role for a factor with thrombosis-inducing activity (TIA).
PUBDATE: 19920101
We treated a patient with lung cancer in whom a hypercoagulopathy was induced acutely by chemotherapy. He received systemic chemotherapy twice and in both instances developed disseminated intravascular coagulopathy (DIC), accompanied by acute decrements of the peripheral platelet count and plasma fibrinogen, an increment of the fibrin degradation products (FDP), and bleeding tendency with the appearance of skin purpura. In each instance, the plasma thrombosis-inducing activity (TIA) appeared one to three days after chemotherapy and subsided subsequently.

8. DOCID:19715 SCORE: 0.0031044887505397
DOCNO: 2087870
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: adverse effects
AUTHOR: L Thür L
AFFILIATION: Evangelischen Krankenhaus Gesundbrunnen, Hofgeismar.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Zeitschrift für Lymphologie. Journal of lymphology.
COUNTRY: GERMANY
TITLE: [High fat diet and risk of breast cancer]
PUBDATE: 19901201
Eating habits, especially high-fat diets, is a topical subject that was also pointedly discussed by renowned authors at the international oncology convention in Hamburg this year. There is a continuing tendency for the incidence of breast cancer to be high in countries with high fat consumption. However, clinical comparative studies have not been able to definitely confirm any correlation between the two; probably because it is not possible to determine eating habits with a sufficient degree of reliability since these change during our lifetime. On the other hand, there is mounting evidence that overweight, rather than a high-fat diet as the result of consuming too many calories, presents the actual risk factor.

9. DOCID:19959 SCORE: 0.00292021331152007
DOCNO: 1622959
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Carcinoma, Squamous Cell
DESCRIPTOR: Pregnancy Complications, Neoplastic
DESCRIPTOR: Tongue Neoplasms
AUTHOR: S A Layton SA
AUTHOR: M Rintoul M
AUTHOR: B S Avery BS
AFFILIATION: Department of Oral and Maxillofacial Surgery, Middlesbrough General Hospital.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: The British journal of oral & maxillofacial surgery.
COUNTRY: SCOTLAND
TITLE: Oral carcinoma in pregnancy.
PUBDATE: 19920601
Oral cancer presenting in pregnancy is a rare combination which, because of current epidemiological changes in the disease, may present more often in the future. Treatment of the condition can be very difficult. Decisions have to be made about terminating the pregnancy or finding a balance between the treatment of the mother and protecting the foetus from the effects of various treatment modalities. This may result in a compromise treatment of the disease. To illustrate the problems, we discuss a case of carcinoma of the tongue presenting in a 23-week pregnant Gravida 1 Para 0 lady, and review the literature.

10. DOCID:22854 SCORE: 0.00292019161188648
DOCNO: 7784155
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiography
QUALIFIER: radiography
QUALIFIER: methods
AUTHOR: F Mimura F
AUTHOR: M Kusumoto M
AUTHOR: R Ono R
AUTHOR: T Nakamura T
AUTHOR: M Endo M
AUTHOR: M Zhang M
AUTHOR: K Kimura K
AUTHOR: E Itouji E
AUTHOR: M Kono M
AFFILIATION: Department of Radiology, Kobe University, School of Medicine.
PUBTYPE: Journal Article
JOURNALTITLE: Nihon Igaku Hōshasen Gakkai zasshi. Nippon acta radiologica.
COUNTRY: JAPAN
TITLE: [Assessment by three-dimensional CT of pleural indentation or invasion by peripheral lung cancer]
PUBDATE: 19950401
We evaluated the effectiveness of three-dimensional (3D) CT for pleural indentation or invasion by peripheral lung cancer adjacent to pleura. Pleural indentation was shown in three of nine cases on conventional CT, and six cases were demonstrated three-dimensionally. 3D-CT was superior to conventional CT in demonstrating pleural indentation. Pleural invasion could not be assessed on 3D-CT because the pleura adjacent to the tumor was not visualized.

11. DOCID:22793 SCORE: 0.00292018226101085
DOCNO: 8979468
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: epidemiology
AUTHOR: D N Rao DN
AUTHOR: P B Desai PB
AUTHOR: B Ganesh B
AFFILIATION: Divn. of Epidemiology & Biostatistics, Tata Memorial Hospital, Parel, Mumbai, India.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Indian journal of cancer.
COUNTRY: INDIA
TITLE: Epidemiological observations on cancer of the oesophagus--a review of Indian studies.
PUBDATE: 19960601
This is an epidemiological review on cancer of the oesophagus. In this attempt, all aspects of epidemiological factors based on national and international studies on oesophageal cancer have been brought out. The problem of this cancer in Indian context has been documented. The association of tobacco and alcohol habits with oesophageal cancer has been confirmed from the studies conducted in India. There is an urgent need to educate the common people about the harmful effect of these two habits and governments and voluntary organisation should take effective steps for its prevention.

12. DOCID:23485 SCORE: 0.00289708267023257
DOCNO: 8960894
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
AUTHOR: R S Bresalier RS
AFFILIATION: Department of Medicine, University of Michigan School of Medicine, Ann Arbor, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Gastroenterology clinics of North America.
COUNTRY: UNITED STATES
TITLE: The biology of colorectal cancer metastasis.
PUBDATE: 19961201
Metastasis is a complex process involving a series of tumor-host interactions that follow tumor initiation and progression. Metastatic cancer cells must be capable of completing all stages of this process to establish secondary foci at distant sites. Most studies infer the functional significance of various observations based on models designed to emphasize the contributions of single molecules or ligand-receptor pairs. While providing useful insights into potential mechanisms of tumorigenesis and metastasis, additional studies are needed to elucidate the complex dynamic interactions involved in these processes. Nonetheless, a better understanding of how tumor cells metastasize is leading to new therapies to prevent and treat micrometastatic disease.

13. DOCID:23423 SCORE: 0.00289706739519319
DOCNO: 8695766
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Genomic Imprinting
QUALIFIER: genetics
AUTHOR: J Squire J
AUTHOR: R Weksberg R
AFFILIATION: Department of Pathology, University of Toronto, Canada.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Seminars in cancer biology.
COUNTRY: UNITED STATES
TITLE: Genomic imprinting in tumours.
PUBDATE: 19960201
In recent years it has become apparent that genomic imprinting may have a role in the development of certain types of cancer. Preferential loss or retention of one parental genotype in chromosomal regions known to be subject to imprinting have been found in specific cancers. This finding raises the possibility that an epigenetic mechanism such as imprinting may alter gene expression and lead to inactivation of tumour suppressor genes or activation or dominant oncogenes. Rearrangements within imprinted chromosomal domains have the potential to influence the stage- and tissue-specific expression of both tumour suppressor and growth promoting genes that cluster to such regions, thus influencing the initiation and progression of cancer.

14. DOCID:23590 SCORE: 0.00287731406459085
DOCNO: 7661576
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: pathology
QUALIFIER: therapy
QUALIFIER: pathology
AUTHOR: N Nishino N
AUTHOR: K Aoki K
AUTHOR: H Konno H
AUTHOR: Y Maruo Y
AUTHOR: T Tanaka T
AUTHOR: I Matsuda I
AUTHOR: T Kanai T
AUTHOR: S Baba S
AFFILIATION: 2nd Dept. of Surgery, Hamamatsu University School of Medicine.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [Postoperative abdominal lymph node recurrence of intrathoracic esophageal cancer with a long-term complete response to radiation and split CF therapy (CDDP and 5-FU)--a case report]
PUBDATE: 19950801
We experienced complete remission in a patient with postoperative abdominal lymph node recurrence of intrathoracic esophageal cancer after treatment with radiation (60Co: 30 Gy) and split CF therapy (CDDP: 20 mg/day + 5-FU: 1 g/day for 5 days). Since then, this patient has remained in complete remission for 43 months with intermittent split CF therapy one or two times a year.