0. DOCID:30781 SCORE: 0.00373756591266423
DOCNO: 14567021
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Infusions, Parenteral
QUALIFIER: administration & dosage
QUALIFIER: pathology
QUALIFIER: drug therapy
QUALIFIER: surgery
AUTHOR: Wansik Yu W
AFFILIATION: School of Medicine, Kyungpook National University Hospital, 50 Samduk-dong Taegu, 700-721, South Korea. wyu@knu.ac.kr
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Surgical oncology clinics of North America.
COUNTRY: United States
TITLE: Impact of perioperative intraperitoneal chemotherapy on the treatment of primary gastric cancer.
PUBDATE: 20030701
Perioperative intraperitoneal chemotherapy provides effective prevention of peritoneal recurrence after resection in advanced gastric cancer, especially in gastric cancer with serosal invasion. With improved local-regional control, improved survival rate for advanced gastric cancer is achieved. This type of regional chemotherapy is an independent treatment-related prognostic factor for advanced gastric cancer. There are several methods of perioperative intraperitoneal chemotherapy. Among them, early postoperative intraperitoneal chemotherapy is simple and easy to perform.


1. DOCID:30767 SCORE: 0.00373755058894656
DOCNO: 12073635
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: diagnostic use
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: Takashi Ohata T
AUTHOR: Yoshinao Abe Y
AUTHOR: Tomisato Miura T
AUTHOR: Tatsusuke Sato T
AFFILIATION: Department of Radiology, Hirosaki University School of Medicine.
PUBTYPE: Journal Article
JOURNALTITLE: Nippon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica.
COUNTRY: Japan
TITLE: [An experimental study for tumor detection by indocyanine green with near-infrared topography]
PUBDATE: 20020501
We studied tumor detection by indocyanine green (ICG) with near-infrared topography in rat experimental tumors: hepatoma AH109A and osteosarcoma POB 102. Time-intensity curves and topograms after ICG injection were obtained in tumors and surrounding normal tissues. Intensities in tumors were slowly reduced, and intensities in normal tissues were rapidly reduced, resulting in positive tumor image in topogram. It is concluded that near-infrared topography enhanced by ICG is useful for cancer detection.


2. DOCID:31139 SCORE: 0.00364695282719594
DOCNO: 15485322
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: radiotherapy
AUTHOR: Boaz Weisz B
AUTHOR: Dror Meirow D
AUTHOR: Eyal Schiff E
AUTHOR: Michael Lishner M
AFFILIATION: Department of Obstetrics and Gynecology, Sheba Medical Center, Tel-Hashomer, Israel. boazmd@inter.net.il
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Expert review of anticancer therapy.
COUNTRY: England
TITLE: Impact and treatment of cancer during pregnancy.
PUBDATE: 20041001
Cancer is the second most common cause of death in the reproductive years and complicates up to one in 1000 pregnancies. When cancer is diagnosed during pregnancy, the management strategy must take into account both the mother and developing fetus. In this article, the four most common malignancies diagnosed in pregnant patients--cervical and breast cancer, malignant melanoma and lymphoma--will be reviewed, with an emphasis on the impact of the diagnosis and management on the pregnant patient and the developing fetus.


3. DOCID:31097 SCORE: 0.00364694325801239
DOCNO: 12833614
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
AUTHOR: V A Kikot' VA
PUBTYPE: Evaluation Studies
PUBTYPE: Journal Article
JOURNALTITLE: Klinichna khirurhiia / Ministerstvo okhorony zdorov'ia Ukraïny, Naukove tovarystvo khirurhiv Ukraïny.
COUNTRY: Ukraine
TITLE: [Comparative effectiveness of various methods of surgical, combined and comprehensive treatment of patients with colonic cancer]
PUBDATE: 20030301
The results of radical treatment of cancer recti using surgical and combined methods, which had envisaged application of preoperative irradiation, systemic chemotherapy with the add of fluorouracil and calcium folinate, intraarterial polychemotherapy with the help of fluorouracil, adriablastinum on background of verapamil, endolymphatic polychemotherapy with local hyperthermy of ultra-high frequency, intraoperative intraperitoneal polychemotherapy and autoimmunotherapy with application of antitumoral vaccine. After application of autoimmunotherapy, endolymphatic polychemotherapy, preoperative intensive gamma-therapy in combined treatment of patients with cancer recti II-III stages the indexes of five-year survival had improved.


4. DOCID:18693 SCORE: 0.00327966653063595
DOCNO: 1511020
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Pleural Effusion, Malignant
AUTHOR: M Tattersall M
AFFILIATION: University of Sydney, New South Wales, Australia.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Current opinion in oncology.
COUNTRY: UNITED STATES
TITLE: Pleural effusions.
PUBDATE: 19920801
Pleural effusions are a common development in patients with cancer. The optimal means of control are not defined, but systemic treatment is often effective in patients with drug-sensitive tumors. Local treatments advocated in the management of malignant pleural effusions differ in the means of drainage, the length of time pleural tubes are left in situ, and the type of intrapleural therapy administered. Randomized trials published in the past few months have suggested that bleomycin sulfate may be superior to tetracycline as a sclerosant and that mitoxantrone does not add to control of effusions compared with large-bore pleural tube alone placed at time of thoracoscopy.


5. DOCID:18644 SCORE: 0.00327964136732685
DOCNO: 1608614
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: enzymology
AUTHOR: I Romics I
AFFILIATION: St. Agnes Hospital, Urológiai Osztály, Bocholt.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Orvosi hetilap.
COUNTRY: HUNGARY
TITLE: [Comparison of the diagnostic value of different tumor markers in prostatic cancer patients]
PUBDATE: 19920601
The author compared the tumour markers of hundred virginell prostatic cancer patients. There were investigated the activity of prostatic acid phosphatase (SP) and its isoenzyme (SPP) by enzymatic method (PAP) as well. The concentration of prostatic specific antigen (PSA) was determined too. The sensibility of markers are growing on the row, SP, SPP, PAP, PSA. Summarising the results, the determination of PAP together with PSA seems to be not necessary. Because of the low price of SP, SPP their determinations is indicated in selected cases. Regarding of costs-benefit the author advises selected investigations in different stage and in different indications.


6. DOCID:23696 SCORE: 0.00321904192051119
DOCNO: 7905152
AUTHOR: I Mittra I
AFFILIATION: Department of Surgery, Tata Memorial Hospital, Bombay, India.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Lancet.
COUNTRY: ENGLAND
TITLE: Breast screening: the case for physical examination without mammography.
PUBDATE: 19940201
Many studies have shown that screening for breast cancer can reduce mortality from the disease. Mammography has come to be regarded as the screening method of choice, but evidence suggests that physical examination (PE) is at least as effective in reducing mortality. Mammography detects many non-infiltrating and small, non-palpable tumours, but we do not know whether these would ever cause symptoms or threaten the woman's life. It is doubtful whether the time gained by early mammographic detection confers any survival benefit over PE detection. PE has substantial advantages over mammography in terms of human and economic costs. The question we should be asking is not how to refine mammographic screening but whether we need it at all.


7. DOCID:23603 SCORE: 0.0032189919770037
DOCNO: 9313857
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Plants, Medicinal
QUALIFIER: isolation & purification
QUALIFIER: chemistry
QUALIFIER: isolation & purification
AUTHOR: J A Beutler JA
AUTHOR: Y Kashman Y
AUTHOR: L K Pannell LK
AUTHOR: J H Cardellina JH
AUTHOR: M R Alexander MR
AUTHOR: M S Balaschak MS
AUTHOR: T R Prather TR
AUTHOR: R H Shoemaker RH
AUTHOR: M R Boyd MR
AFFILIATION: Laboratory of Drug Discovery Research & Development, National Cancer Institute, Frederick, MD 21702-1201, USA.
PUBTYPE: Journal Article
JOURNALTITLE: Bioorganic & medicinal chemistry.
COUNTRY: ENGLAND
TITLE: Isolation and characterization of novel cytotoxic saponins from Archidendron ellipticum.
PUBDATE: 19970801
A series of new ester saponins, elliptosides A-J, has been isolated from the tropical plant Archidendron ellipticum (Leguminosae). These saponins were particularly cytotoxic to certain renal and melanoma cancer cell lines in the NCI's 60-cell line human tumor screen. The structures of elliptosides A, E, and F were elucidated by spectroscopic and chemical means. Elliptoside A showed in vivo antitumor activity against the LOX melanoma cell line.


8. DOCID:25906 SCORE: 0.00320976388752809
DOCNO: 10193595
AUTHOR: B A Johnson BA
AFFILIATION: Hamot Family Practice Residency Program, Erie, Pennsylvania, USA.
PUBTYPE: Corrected and Republished Article
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: American family physician.
COUNTRY: UNITED STATES
TITLE: Flexible sigmoidoscopy: screening for colorectal cancer.
PUBDATE: 19990301
Flexible sigmoidoscopy is an important screening procedure because of its ability to detect early changes in the distal colon. The 60-cm flexible sigmoidoscope provides excellent visualization with minimal discomfort to patients. Successful sigmoidoscopy requires adequate patient preparation, proper equipment and an experienced examiner who can recognize both normal and abnormal findings. Complications arising from sigmoidoscopy are rare, but patients may experience some cramping, gas or watery stools. Screening and primary preventive measures, including regular exercise and increased dietary fiber intake, can lower the morbidity and mortality associated with colorectal cancer.


9. DOCID:27999 SCORE: 0.00320850940057698
DOCNO: 12057053
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
AUTHOR: S K Gibbons SK
AUTHOR: H M Keys HM
AFFILIATION: Department of Radiation Oncology, MC-95, Albany Medical Center, 43 New Scotland Avenue, Albany, NY 12208, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Current treatment options in oncology.
COUNTRY: United States
TITLE: Advanced cervical cancer.
PUBDATE: 20000601
Several large, prospectively randomized clinical trials run by multi-institutional cooperative groups have established that the best treatment for advanced cancer of the cervix is primary radiotherapy with concurrent, cisplatin-based chemotherapy. In fact, patients with earlier stage cervix cancer with poor prognostic indicators (large, bulky tumors, positive pelvic lymph nodes, or unexpected parametrial disease at the time of surgery) also show a survival benefit with this approach. Adequate radiation dosing (both external beam and intracavitary) is essential. The additional benefit of periaortic lymph node irradiation is debated, but generally accepted, for patients with locally advanced disease or pelvic lymph node involvement.


10. DOCID:30574 SCORE: 0.00317903072248256
DOCNO: 12478855
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Mastectomy, Segmental
QUALIFIER: therapeutic use
QUALIFIER: surgery
AUTHOR: Takashi Fukutomi T
AFFILIATION: National Cancer Center Hospital, Breast Surgery Division, Tokyo, Japan.
PUBTYPE: Journal Article
JOURNALTITLE: Nippon Geka Gakkai zasshi.
COUNTRY: Japan
TITLE: [Option of the surgical mode for breast cancer based on the effect of neoadjuvant chemotherapy]
PUBDATE: 20021101
Neoadjuvant chemotherapy has become standard treatment for breast cancer patients to avoid mastectomy in larger tumors. Neoadjuvant chemotherapy permits more breast-conserving surgery to be performed. The treatment outcome is favorable in women whose tumors show a complete pathological response. Histological grade, HER-2, p53, and hormone receptor status are significant predictive factors of a good pathological response to neoadjuvant chemotherapy. In addition, computed tomography and/or magnetic resonance imaging are useful tools in determining the optimal resection area for breast cancer.


11. DOCID:30555 SCORE: 0.00317902097171174
DOCNO: 12170885
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Paraneoplastic Syndromes
DESCRIPTOR: Skin Diseases
AUTHOR: Sarah Boyce S
AUTHOR: Julie Harper J
AFFILIATION: Department of Dermatology, University of Alabama at Birmingham, EFH, Suite 414, Birmingham, AL 35294, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Dermatologic clinics.
COUNTRY: United States
TITLE: Paraneoplastic dermatoses.
PUBDATE: 20020701
Skin manifestations of systemic disease and malignancy are protean. The recognition of a potentially paraneoplastic dermatosis as such must prompt an investigation for occult malignancy. Lack of familiarity with cutaneous clues of internal malignancy may delay diagnosis and treatment of cancer. It is important to consider a paraneoplastic process in the differential diagnosis of a number of eruptive and treatment-resistant dermatoses. These dermatoses may be the first sign of an occult neoplasm. Their recognition may assist in cancer detection and the swift induction of appropriate therapy.


12. DOCID:27969 SCORE: 0.00317697610894408
DOCNO: 11147228
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
AUTHOR: R A Larson RA
AFFILIATION: Section of Hematology/Oncology, Department of Medicine and Cancer Research Center, University of Chicago, Chicago, Ilinois, USA. rlarson@medicine.bsd.uchicago.edu
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Hematology/oncology clinics of North America.
COUNTRY: United States
TITLE: Recent clinical trials in acute lymphocytic leukemia by the Cancer and Leukemia Group B.
PUBDATE: 20001201
The Cancer and Leukemia Group B (CALGB) has performed a series of studies evaluating different aspects of remission induction and postremission treatment in adults with acute lymphocytic leukemia (ALL). In recent years, these clinical trials have been supplemented by systematic morphologic, immunophenotyping, cytogenetic, and molecular genetic studies leading to the identification of different risk groups of patients who may warrant individualized treatments. These protocols have enrolled all adult patients older than 15 years with ALL, without an upper age restriction, and did not exclude Philadelphia (Ph) chromosome-positive patients.


13. DOCID:27924 SCORE: 0.00317695871216401
DOCNO: 10783521
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pharmacology
QUALIFIER: drug therapy
QUALIFIER: pharmacology
AUTHOR: R Schlemmer R
AUTHOR: T Spruss T
AUTHOR: G Bernhardt G
AUTHOR: H Schönenberger H
AFFILIATION: Lehrstuhl für Pharmazeutische Chemie II, Universität Regensburg, Germany.
PUBTYPE: Journal Article
JOURNALTITLE: Archiv der Pharmazie.
COUNTRY: GERMANY
TITLE: Does [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]- dichloroplatinum(II) act on the hormone-sensitive, murine breast cancer as a biological response modifier? Part 1: The MXT-M-3.2 breast cancer stimulates the growth of an identical second graft; [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]dichloroplat inum (II) inhibits this process.
PUBDATE: 20000301
The MXT-M-3.2 breast cancer implanted into female B6D2F1 mice accelerates the growth of an identical second tumor. This process is inhibited by [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl) ethylenediamine]dichloroplatinum(II). The possible modes of action of this compound as a biological response modifier are discussed.


14. DOCID:19937 SCORE: 0.00316670597381359
DOCNO: 1744461
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: blood
QUALIFIER: blood
QUALIFIER: chemically induced
AUTHOR: Y Matsuura Y
AUTHOR: M Shinohara M
AUTHOR: M Kashimura M
AUTHOR: S Baba S
AUTHOR: H Otsuka H
AUTHOR: Y Okamura Y
AFFILIATION: Department of Obstetrics and Gynecology, University of Occupational and Environmental Health, Fukuoka.
PUBTYPE: Journal Article
JOURNALTITLE: Nippon Sanka Fujinka Gakkai zasshi.
COUNTRY: JAPAN
TITLE: [Disorder of serum electrolytes following CAP therapy]
PUBDATE: 19911201
Combination chemotherapy with Cyclophosphamide, Adriamycin and Cisplatin (CAP) is one of the most effective chemotherapies for ovarian cancer. Severe vomiting induced by this treatment may cause a disorder of the serum electrolytes. Severe hyponatremia was observed in one patient who complained of convulsions and unconsciousness. Accordingly we studied the disorder of serum electrolytes in 158 courses of CAP treatment (44 patients) during the five years from 1984 to 1988. The serum electrolytes were influenced by the amount of vomiting in this study. Consequently frequent examination of serum electrolytes is necessary during this treatment.