0. DOCID:19951 SCORE: 0.00426102110034623
DOCNO: 1280094
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: secondary
QUALIFIER: secondary
AUTHOR: R G Doig RG
AUTHOR: I N Olver IN
AUTHOR: P N Jeal PN
AUTHOR: J F Bishop JF
AFFILIATION: Peter MacCallum Cancer Institute, Melbourne, Vic., Australia.
PUBTYPE: Journal Article
JOURNALTITLE: Australian and New Zealand journal of medicine.
COUNTRY: AUSTRALIA
TITLE: Symptomatic choroidal metastases in breast cancer.
PUBDATE: 19920801
A series of 21 consecutive patients with carcinoma of the breast and symptomatic choroidal metastases was reviewed. All patients were symptomatic of choroidal metastases at presentation. Most patients had disease progression at other sites at the time of diagnosis. The incidence of cerebral metastases was not increased in this group compared to that in patients with metastatic breast cancer at other sites. Radiotherapy using a direct anterior field proved effective palliation for this disease site. Of the 32 eyes treated, serial visual acuity was documented in 23. Seventeen showed objective improvement and six showed stabilisation. The median duration of improvement was 11.5 months.


1. DOCID:19253 SCORE: 0.00351564604413034
DOCNO: 2014871
AUTHOR: J Mandelblatt J
AUTHOR: H Andrews H
AUTHOR: J Kerner J
AUTHOR: A Zauber A
AUTHOR: W Burnett W
AFFILIATION: Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY 10021.
PUBTYPE: Journal Article
JOURNALTITLE: American journal of public health.
COUNTRY: UNITED STATES
TITLE: Determinants of late stage diagnosis of breast and cervical cancer: the impact of age, race, social class, and hospital type.
PUBDATE: 19910501
Previous studies of the relationship between cancer stage, age, and race have not controlled for social class and health care setting. Logistic regression analyses, using information from the New York State Tumor Registry and area-level social class indicators, demonstrated that, in New York City, older Black, lower class women in public hospitals were 3.75 and 2.54 times more likely to have late stage breast or cervical cancer, respectively, than were younger White, high social class women in non-public hospitals.


2. DOCID:19449 SCORE: 0.00302359833741241
DOCNO: 1694002
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: radiotherapy
AUTHOR: N A Azhigaliev NA
AUTHOR: S K Kusherbaev SK
AUTHOR: S S Sadykov SS
AUTHOR: A A Asanov AA
AUTHOR: S Z Fel'dman SZ
PUBTYPE: Journal Article
JOURNALTITLE: Meditsinskaia radiologiia.
COUNTRY: USSR
TITLE: [Results of radiation and chemoradiation therapy in esophageal cancer]
PUBDATE: 19900601
Eight therapeutic variants were worked out for 602 patients with esophageal cancer: 61 patients entered in the control group. The latter received routine radiation therapy. The results of therapy of 496 patients were studied. The most promising method was chemoradiotherapy using multifractionation of a daily dose of irradiation, the 4-year survival rate of 20% being achieved. For combination with radiation therapy the following schemes of chemotherapeutic agents were used bleomycin-methotrexate-prospidine, bleomycin-adriamycin-methotrexate, dactinomycin-methotrexate-prospidine, methotrexate-prospidine. Intensive detoxication therapy with parenteral feeding is recommended to decrease the frequency of complications and to improve therapy tolerance.


3. DOCID:19396 SCORE: 0.00302358771236043
DOCNO: 1633773
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: methods
QUALIFIER: pathology
QUALIFIER: ultrasonography
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: H Grimm H
AUTHOR: K Hamper K
AUTHOR: K F Binmoeller KF
AUTHOR: N Soehendra N
AFFILIATION: Dept. of Endoscopic Surgery, University Hospital of Hamburg.
PUBTYPE: Journal Article
JOURNALTITLE: Endoscopy.
COUNTRY: GERMANY
TITLE: Enlarged lymph nodes: malignant or not?
PUBDATE: 19920501
Prospective controlled data of lymph node evaluation by endoscopic ultrasound in esophageal, gastric and pancreatic cancer is presented. Lymph node pattern, changes of boundaries and echogenicity were considered. Preoperative findings of endoscopic ultrasound were classified according to TNM staging. Only those cases with subsequent histologic examination of the resected specimen were entered into the study. Sensitivity of endoscopic ultrasonography (EUS) was 90% for esophageal and 87% for gastric cancer. The specificity was 72% and 88%, respectively. In spite of the overall satisfactory results of EUS in evaluation of lymph nodes, further improvement in detection and differentiation of benign and malignant nodes is required.


4. DOCID:19891 SCORE: 0.00278916602949096
DOCNO: 1315669
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: chemistry
QUALIFIER: analysis
QUALIFIER: chemistry
AUTHOR: B Zhu B
AFFILIATION: Bethune University of Medical Sciences Third Hospital, Changchun, Jilin.
PUBTYPE: Journal Article
JOURNALTITLE: Zhonghua zhong liu za zhi [Chinese journal of oncology].
COUNTRY: CHINA
TITLE: [Detection of estrogen receptors (ER) in gastric cancer]
PUBDATE: 19921101
Using Avidn-biotin-peroxidase complex (ABC) immunohistochemical method, 68 gastric cancer specimens and 20 non-cancerous stomach specimens were examined for ER. In 38 of 68 gastric cancer specimens, ER concentrations were also biochemically determined by Dextran-coated charcoal (DCC) assay. The results showed that ER was absent in noncancerous stomach tissues. ER was present in 21 (30.9%) of gastric cancers. The ER positive cases were chiefly poorly differentiated gastric cancers. There were no significant statistical differences in the patient's age or sex, size of primary tumor and the ER positive rates. The results indicate that endocrine therapy might be useful for the ER positive gastric cancer patients.


5. DOCID:18196 SCORE: 0.00276031626188842
DOCNO: 1722579
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Prenatal Diagnosis
QUALIFIER: diagnosis
QUALIFIER: analysis
AUTHOR: J M Van Lith JM
AFFILIATION: Department of Obstetrics and Gynaecology, University Hospital Groningen, The Netherlands.
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
PUBTYPE: Multicenter Study
JOURNALTITLE: Prenatal diagnosis.
COUNTRY: ENGLAND
TITLE: First-trimester screening for fetal chromosomal abnormalities. Preliminary results. Dutch Working Party on Prenatal Diagnosis.
PUBDATE: 19910801
We have started a multicentre trial to study the possibilities of first-trimester maternal serum screening for fetal chromosomal abnormalities. Maternal blood samples were obtained before 13 weeks of gestation. We present the preliminary results of the first 950 patients on alpha-fetoprotein (AFP). Results on cancer antigen 125 (CA 125) in Down's syndrome and normal pregnancies are also presented. We conclude that the results on AFP are promising and that CA 125 might be predictive for fetal Down's syndrome.


6. DOCID:18205 SCORE: 0.00271038897154097
DOCNO: 1859330
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Mammography
QUALIFIER: radiography
QUALIFIER: radiography
QUALIFIER: radiography
AUTHOR: L E Albertyn LE
AUTHOR: A C Drew AC
AFFILIATION: Department of Radiology, Queen Elizabeth Hospital, Woodville, South Australia.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Australasian radiology.
COUNTRY: AUSTRALIA
TITLE: Mammographically detected microcalcifications due to pseudoxanthoma elasticum.
PUBDATE: 19910201
Mammographic detection and analysis of microcalcification is a key component in the detection of early breast cancer. A casting configuration or granular morphology has a strong association with malignancy. These are relatively easily recognised, but with the proliferation of mammographic screening, other varieties of calcification are being encountered which may pose diagnostic dilemmas. This case report describes the findings in a patient with Pseudoxanthoma Elasticum (PXE) who presented in this way. To our knowledge, this has not previously been documented. Such calcification is not usually visible on conventional radiographs.


7. DOCID:19874 SCORE: 0.0026677903169107
DOCNO: 1467164
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Stem Cell Transplantation
QUALIFIER: administration & dosage
QUALIFIER: drug therapy
AUTHOR: N J Meropol NJ
AUTHOR: B A Overmoyer BA
AUTHOR: E A Stadtmauer EA
AFFILIATION: Hematology-Oncology Division, University of Pennsylvania Medical Center, Philadelphia.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Oncology (Williston Park, N.Y.)
COUNTRY: UNITED STATES
TITLE: High-dose chemotherapy with autologous stem cell support for breast cancer.
PUBDATE: 19921201
Breast cancer is a major public health issue, expected to affect one out of nine women over a lifetime. High-dose chemotherapy with autologous stem cell support is a current approach to the management of metastatic breast cancer and high-risk primary breast cancer. This review considers the effectiveness of this modality in the treatment of breast cancer in an effort to define its role in overall patient management. Current research directions, including technical advances aimed at reducing toxicity, are discussed. Finally, controversies regarding the role of third-party payers in the investigational process are considered.


8. DOCID:18301 SCORE: 0.00254224168709926
DOCNO: 8033723
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: methods
AUTHOR: S Z Guo SZ
AFFILIATION: Xijing Hospital, Fourth Military Medical University, Xian.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Zhonghua wai ke za zhi [Chinese journal of surgery].
COUNTRY: CHINA
TITLE: [Anterolateral femoral flap for chronic skull osteomyelitis]
PUBDATE: 19930901
Three patients had chronic skull osteomyelitis resulted from post-burn alopecia. One of them had local canceration. After massive resection of bone for osteomyelitis, the area of tissue defect was 15 cm x 20 cm, 15 cm x 16 cm and 11 cm x 15 cm respectively. Anterolateral femoral free flap transfer was used successfully to cover the defects. Since there are dangers of spreading infection in to intracranial and local canceration, chronic osteomyelitis of skull should be treated as early as possible, and the focus should be cleansed thoroughly.


9. DOCID:19831 SCORE: 0.00248811486375642
DOCNO: 1979751
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Terminal Care
QUALIFIER: administration & dosage
QUALIFIER: complications
QUALIFIER: drug therapy
AUTHOR: W D Rees WD
AFFILIATION: St. Mary's Hospice, Selly Park, Birmingham.
PUBTYPE: Journal Article
JOURNALTITLE: Clinical oncology (Royal College of Radiologists (Great Britain))
COUNTRY: ENGLAND
TITLE: Opioid needs of terminal care patients: variations with age and primary site.
PUBDATE: 19900301
The records of 1383, terminal cancer patients have been reviewed to determine whether opioid requirements vary in a consistent pattern with age and with site of primary cancer. Opioid requirements are shown to decrease with age in a regular pattern and from early adult life. Opioid requirements also differ significantly with site of primary cancer and there appears to be a discernible pattern of opioid need for different cancers. Patients with sexually related cancer have the highest opioid requirements, irrespective of sex. When the sexually determined cancers are excluded, the analgesic needs of men and women are not significantly different (P = 0.191).


10. DOCID:17866 SCORE: 0.00247345336977869
DOCNO: 8426412
AUTHOR: J Adolfsson J
AFFILIATION: Department of Urology, Karolinska Hospital, Stockholm, Sweden.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The Journal of urology.
COUNTRY: UNITED STATES
TITLE: Deferred treatment of low grade stage T3 prostate cancer without distant metastases.
PUBDATE: 19930201
Fifty patients with extracapsular prostate cancer without known distant metastases were included in a protocol of surveillance followed by deferred treatment of progression. The median observed followup time was 78 months. The risk of developing distant metastases, if not dying before, was 24% and 37% at 5 and 9 years, respectively. The risk of dying of prostate cancer, if not dying of other diseases before, was 12% and 30% at 5 and 9 years, respectively. Thus, the cancer specific survival was 88% at 5 years and 70% at 9 years.


11. DOCID:19289 SCORE: 0.00247078255664875
DOCNO: 8218404
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: metabolism
QUALIFIER: chemistry
QUALIFIER: genetics
AUTHOR: M Puder M
AUTHOR: G F Barnard GF
AUTHOR: R J Staniunas RJ
AUTHOR: G D Steele GD
AUTHOR: L B Chen LB
AFFILIATION: Division of Cellular and Molecular Biology, Dana-Farber Cancer Institute Harvard Medical School, Boston, MA.
PUBTYPE: Journal Article
JOURNALTITLE: Biochimica et biophysica acta.
COUNTRY: NETHERLANDS
TITLE: Nucleotide and deduced amino acid sequence of human ribosomal protein L18.
PUBDATE: 19931001
Ribosomal protein L18 mRNA is overexpressed in human colorectal cancer compared to normal colon tissue. We report the nucleotide sequence of human L18 cDNA derived from a normal colon source. There were no mutational changes in segments of L18 cDNA derived from two tumor sources. The L18 cDNA was 690 base pairs long and predicts a single open reading frame of 564 nucleotides, encoding 188 amino acids with a M(r) = 21,621, it is homologous to rat L18 and Xenopus laevis L14.


12. DOCID:19983 SCORE: 0.002447422734602
DOCNO: 2264353
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
AUTHOR: H Kucera H
AFFILIATION: I. Universit├Ąts-Frauenklinik, Wien.
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
JOURNALTITLE: Wiener medizinische Wochenschrift (1946)
COUNTRY: AUSTRIA
TITLE: [The significance of postoperative radiotherapy in cervix and uterine cancer]
PUBDATE: 19901001
The benefit of adjuvant radiotherapy of operated cervical and endometrial cancer is not clear. In a prospective trial of 571 endometrial cancers stage I, cases with poor prognosticators are treated additionally with external pelvic irradiation (Co 60, 56 Gy) and show nearly the same outcome as cases with good prognosticators and without such an adjuvant therapy. A benefit of adjuvant irradiation of cervical carcinoma stage I/b could only be shown in cases with similar histopathologic characteristics (tumor volume, grading, vessel invasion, lymphnode involvement). In a retrospective study 171 cases of cervical carcinoma were analyzed. With adjuvant external irradiation the relapse free interval was longer and 5-year survival better than without such an adjuvant therapy.


13. DOCID:19780 SCORE: 0.00243673791771242
DOCNO: 1449974
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Polymerase Chain Reaction
QUALIFIER: genetics
AUTHOR: A L Hooberman AL
AFFILIATION: Department of Medicine, University of Chicago.
PUBTYPE: Journal Article
JOURNALTITLE: Oncology (Williston Park, N.Y.)
COUNTRY: UNITED STATES
TITLE: The use of the polymerase chain reaction in clinical oncology.
PUBDATE: 19920901
The polymerase chain reaction (PCR) is an extraordinary tool for studying cancer. It is both more sensitive and more rapid than any other detection method, and can be performed without special expertise. It is ideal for the detection of minimal residual disease, particularly in lymphoid malignancies, but also for any cancer with a genetic abnormality that is defined at the molecular level. Other uses, such as diagnosis of cancer based on detection of translocations or point mutations, have an intriguing potential, but remain investigational. At this point, few clinicians would be willing to base a diagnosis, let alone a treatment plan, on a diagnosis based on PCR findings without confirming histology.


14. DOCID:17376 SCORE: 0.00237244601930209
DOCNO: 2389966
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Balloon Dilatation
QUALIFIER: therapeutic use
QUALIFIER: drug effects
QUALIFIER: therapy
QUALIFIER: administration & dosage
QUALIFIER: therapy
AUTHOR: T Kondoh T
AUTHOR: Y Nakagiri Y
AUTHOR: T Sano T
AUTHOR: T Hirose T
AUTHOR: Y Ohmura Y
AUTHOR: A Hongoh A
AUTHOR: K Sekiba K
AFFILIATION: Dept. of Obstetrics and Gynecology, Okayama University School of Medicine.
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [Preoperative intraarterial infusion chemotherapy in combination with angiotensin II pressor by BOAI method in cervical cancer]
PUBDATE: 19900801
We performed preoperative intraarterial infusion chemotherapy of CDDP in combination with angiotensin II pressor for cervical cancer, and the balloon occluded infusion (BOAI) method was used. Pt concentration and histological change in surgical specimens were investigated, and the efficacy of BOAI method was estimated.