0. DOCID:19951 SCORE: 0.00426102110034623
DOCNO: 1280094
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: secondary
QUALIFIER: secondary
AUTHOR: R G Doig RG
AUTHOR: I N Olver IN
AUTHOR: P N Jeal PN
AUTHOR: J F Bishop JF
AFFILIATION: Peter MacCallum Cancer Institute, Melbourne, Vic., Australia.
PUBTYPE: Journal Article
JOURNALTITLE: Australian and New Zealand journal of medicine.
COUNTRY: AUSTRALIA
TITLE: Symptomatic choroidal metastases in breast cancer.
PUBDATE: 19920801
A series of 21 consecutive patients with carcinoma of the breast and symptomatic choroidal metastases was reviewed. All patients were symptomatic of choroidal metastases at presentation. Most patients had disease progression at other sites at the time of diagnosis. The incidence of cerebral metastases was not increased in this group compared to that in patients with metastatic breast cancer at other sites. Radiotherapy using a direct anterior field proved effective palliation for this disease site. Of the 32 eyes treated, serial visual acuity was documented in 23. Seventeen showed objective improvement and six showed stabilisation. The median duration of improvement was 11.5 months.

1. DOCID:19253 SCORE: 0.00351564604413034
DOCNO: 2014871
AUTHOR: J Mandelblatt J
AUTHOR: H Andrews H
AUTHOR: J Kerner J
AUTHOR: A Zauber A
AUTHOR: W Burnett W
AFFILIATION: Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY 10021.
PUBTYPE: Journal Article
JOURNALTITLE: American journal of public health.
COUNTRY: UNITED STATES
TITLE: Determinants of late stage diagnosis of breast and cervical cancer: the impact of age, race, social class, and hospital type.
PUBDATE: 19910501
Previous studies of the relationship between cancer stage, age, and race have not controlled for social class and health care setting. Logistic regression analyses, using information from the New York State Tumor Registry and area-level social class indicators, demonstrated that, in New York City, older Black, lower class women in public hospitals were 3.75 and 2.54 times more likely to have late stage breast or cervical cancer, respectively, than were younger White, high social class women in non-public hospitals.

2. DOCID:23222 SCORE: 0.00303995777126296
DOCNO: 9063491
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pharmacology
QUALIFIER: drug therapy
AUTHOR: S Fujimoto S
AFFILIATION: Division of Chemotherapy, Chiba Cancer Center Research Institute.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [Theory and actual attempts to establish an effective cancer chemotherapy]
PUBDATE: 19970201
In order to establish an effective cancer chemotherapy, theoretical analyses of chemoresistance factors in recurrent patients and possible approaches to curative chemotherapy were undertaken. Multidrug resistance of tumor cells in recurrent patients may hamper the development of new antitumor agents. Thus, we developed a new screening method (FACS method) which employs fresh clinical specimens. By this method, TAS-103 was found to be far more effective than 10 standard drugs and to be one of the most effective drugs among 20 or more new antitumor agents under study. Development of several effective drugs, such as TAS-103, might lead to a curative cancer chemotherapy.

3. DOCID:19449 SCORE: 0.00302359833741241
DOCNO: 1694002
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: radiotherapy
AUTHOR: N A Azhigaliev NA
AUTHOR: S K Kusherbaev SK
AUTHOR: S S Sadykov SS
AUTHOR: A A Asanov AA
AUTHOR: S Z Fel'dman SZ
PUBTYPE: Journal Article
JOURNALTITLE: Meditsinskaia radiologiia.
COUNTRY: USSR
TITLE: [Results of radiation and chemoradiation therapy in esophageal cancer]
PUBDATE: 19900601
Eight therapeutic variants were worked out for 602 patients with esophageal cancer: 61 patients entered in the control group. The latter received routine radiation therapy. The results of therapy of 496 patients were studied. The most promising method was chemoradiotherapy using multifractionation of a daily dose of irradiation, the 4-year survival rate of 20% being achieved. For combination with radiation therapy the following schemes of chemotherapeutic agents were used bleomycin-methotrexate-prospidine, bleomycin-adriamycin-methotrexate, dactinomycin-methotrexate-prospidine, methotrexate-prospidine. Intensive detoxication therapy with parenteral feeding is recommended to decrease the frequency of complications and to improve therapy tolerance.

4. DOCID:19396 SCORE: 0.00302358771236043
DOCNO: 1633773
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: methods
QUALIFIER: pathology
QUALIFIER: ultrasonography
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: H Grimm H
AUTHOR: K Hamper K
AUTHOR: K F Binmoeller KF
AUTHOR: N Soehendra N
AFFILIATION: Dept. of Endoscopic Surgery, University Hospital of Hamburg.
PUBTYPE: Journal Article
JOURNALTITLE: Endoscopy.
COUNTRY: GERMANY
TITLE: Enlarged lymph nodes: malignant or not?
PUBDATE: 19920501
Prospective controlled data of lymph node evaluation by endoscopic ultrasound in esophageal, gastric and pancreatic cancer is presented. Lymph node pattern, changes of boundaries and echogenicity were considered. Preoperative findings of endoscopic ultrasound were classified according to TNM staging. Only those cases with subsequent histologic examination of the resected specimen were entered into the study. Sensitivity of endoscopic ultrasonography (EUS) was 90% for esophageal and 87% for gastric cancer. The specificity was 72% and 88%, respectively. In spite of the overall satisfactory results of EUS in evaluation of lymph nodes, further improvement in detection and differentiation of benign and malignant nodes is required.

5. DOCID:23755 SCORE: 0.00300387150739969
DOCNO: 7548841
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: physiology
QUALIFIER: metabolism
QUALIFIER: physiology
QUALIFIER: physiology
AUTHOR: A Eastman A
AFFILIATION: Department of Pharmacology and Toxicology, Dartmouth Medical School, Hanover, NH 03755, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Seminars in cancer biology.
COUNTRY: UNITED STATES
TITLE: Survival factors, intracellular signal transduction, and the activation of endonucleases in apoptosis.
PUBDATE: 19950201
Cell survival is normally mediated by factors in the extracellular environment, whereas genetic changes that constitutively activate intracellular survival pathways often occur in cancer. It is suggested that a Ras/Raf/MAP kinase-dependent pathway is critical for cell survival. Apoptosis results from loss of these survival factors or deregulation of survival pathways. If protein kinase cascades mediate survival, then it is likely that phosphatases mediate apoptosis. Potential targets for dephosphorylation include regulators of ion homeostasis as these have been implicated in the regulation of endonucleases associated with apoptosis. Survival factors also modulate anticancer drug response and understanding these pathways may improve therapy.

6. DOCID:31198 SCORE: 0.00298253088354586
DOCNO: 12724086
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: complications
QUALIFIER: diagnosis
QUALIFIER: pathology
AUTHOR: S Schuffelmann Gutiérrez S
AUTHOR: J M Merino Arribas JM
AUTHOR: A I Elvira Pardilla AI
AUTHOR: J M Montero Macarro JM
AUTHOR: A L Camino Fernández AL
AFFILIATION: Sección de Escolares. Servicio de Pediatría. Hospital General Yagüe. Burgos. España. jmmrino@hgy.es
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Anales de pediatría (Barcelona, Spain : 2003)
COUNTRY: Spain
TITLE: [Muscle tumor in a girl with HIV infection: extranodal non-Hodgkin's lymphoma]
PUBDATE: 20030501
Non-Hodgkin's lymphomas are the most common cancers in children with human immunodeficiency virus (HIV) infection. Extranodal disease is the most common form of clinical presentation. Treatment with aggressive chemotherapy and highly active antiretroviral therapy has improved the prognosis of these children. We present a 10-year-old severely immunocompromised girl with HIV infection and non-Hodgkin's lymphoma manifested by a muscle mass.

7. DOCID:23195 SCORE: 0.00289261914319856
DOCNO: 8047476
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Advance Directives
DESCRIPTOR: Information Dissemination
QUALIFIER: therapy
QUALIFIER: methods
AUTHOR: D E Neumark DE
AFFILIATION: University of Pennsylvania School of Nursing, Philadelphia.
PUBTYPE: Journal Article
JOURNALTITLE: Oncology nursing forum.
COUNTRY: UNITED STATES
TITLE: Providing information about advance directives to patients in ambulatory care and their families.
PUBDATE: 19940501
PURPOSE/OBJECTIVES: To devise a teaching pamphlet on advance directives. DATA SOURCES: Published articles, professional publications, books. DATA SYNTHESIS: Content was designed to educate, increase awareness of the topic, and encourage dialogue among caregivers, patients, and families prior to the onset of a health crisis. The tool is written at a fifth-grade reading level. CONCLUSIONS: The booklet can achieve its goals. Dissemination strategies still are under discussion. IMPLICATIONS FOR NURSING PRACTICE: Helping patients and their families explore end-of-life decisions is vital to providing comprehensive care for patients with cancer. Tools such as this can facilitate that process.

8. DOCID:22935 SCORE: 0.00285577835815681
DOCNO: 7920740
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: standards
PUBTYPE: Guideline
PUBTYPE: Journal Article
PUBTYPE: Practice Guideline
JOURNALTITLE: Clinical practice guideline. Quick reference guide for clinicians.
COUNTRY: UNITED STATES
TITLE: High-quality mammography: information for referring providers. Agency for Health Care Policy and Research.
PUBDATE: 19941001
This Quick Reference Guide for Clinicians contains highlights from Quality Determinants of Mammography, Clinical Practice Guideline No. 13 of interest to health care providers who refer women for mammography. The Quality Determinants of Mammography Guideline Panel, a private-sector panel of health care professionals and consumers, developed the Guideline after comprehensively analyzing the research literature and current scientific knowledge concerning elements necessary for high-quality mammography. Specific recommendations are made in the following areas: Components of complete breast cancer screening; Responsibilities of women, mammography facilities,and referring providers as to screening and followup care; Communication of results; Limitations of mammography; Certification of mammography facilities.

9. DOCID:22626 SCORE: 0.00283517725218508
DOCNO: 9156943
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
AUTHOR: J Rolski J
AUTHOR: M Pawlicki M
AUTHOR: T Zemełka T
AUTHOR: J Pernal J
AFFILIATION: Kliniki Chemioterapii Centrum Onkologii im. M. Skłodowskiej-Curie, Oddział w Krakowie.
PUBTYPE: Journal Article
JOURNALTITLE: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego.
COUNTRY: POLAND
TITLE: [Results of tamoxifen treatment in patients with advanced breast cancer]
PUBDATE: 19961001
The results of advanced breast cancer therapy with tamoxifen have been evaluated. The objective response to the drug has been achieved in 32 (31.7%) patients, and a 2-year survival in 52% of cases. A correlation between the localization of lesions and response rate has been found. The best results have been achieved in localized lesions and lymph nodes metastases. Low toxicity of the drug enables achievement of results comparable to those seen in all types of the hormonal therapy, except androgens.

10. DOCID:19891 SCORE: 0.00278916602949096
DOCNO: 1315669
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: chemistry
QUALIFIER: analysis
QUALIFIER: chemistry
AUTHOR: B Zhu B
AFFILIATION: Bethune University of Medical Sciences Third Hospital, Changchun, Jilin.
PUBTYPE: Journal Article
JOURNALTITLE: Zhonghua zhong liu za zhi [Chinese journal of oncology].
COUNTRY: CHINA
TITLE: [Detection of estrogen receptors (ER) in gastric cancer]
PUBDATE: 19921101
Using Avidn-biotin-peroxidase complex (ABC) immunohistochemical method, 68 gastric cancer specimens and 20 non-cancerous stomach specimens were examined for ER. In 38 of 68 gastric cancer specimens, ER concentrations were also biochemically determined by Dextran-coated charcoal (DCC) assay. The results showed that ER was absent in noncancerous stomach tissues. ER was present in 21 (30.9%) of gastric cancers. The ER positive cases were chiefly poorly differentiated gastric cancers. There were no significant statistical differences in the patient's age or sex, size of primary tumor and the ER positive rates. The results indicate that endocrine therapy might be useful for the ER positive gastric cancer patients.

11. DOCID:18196 SCORE: 0.00276031626188842
DOCNO: 1722579
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Prenatal Diagnosis
QUALIFIER: diagnosis
QUALIFIER: analysis
AUTHOR: J M Van Lith JM
AFFILIATION: Department of Obstetrics and Gynaecology, University Hospital Groningen, The Netherlands.
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
PUBTYPE: Multicenter Study
JOURNALTITLE: Prenatal diagnosis.
COUNTRY: ENGLAND
TITLE: First-trimester screening for fetal chromosomal abnormalities. Preliminary results. Dutch Working Party on Prenatal Diagnosis.
PUBDATE: 19910801
We have started a multicentre trial to study the possibilities of first-trimester maternal serum screening for fetal chromosomal abnormalities. Maternal blood samples were obtained before 13 weeks of gestation. We present the preliminary results of the first 950 patients on alpha-fetoprotein (AFP). Results on cancer antigen 125 (CA 125) in Down's syndrome and normal pregnancies are also presented. We conclude that the results on AFP are promising and that CA 125 might be predictive for fetal Down's syndrome.

12. DOCID:21590 SCORE: 0.002746944177485
DOCNO: 8645029
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: metabolism
QUALIFIER: secondary
QUALIFIER: drug therapy
AUTHOR: H Tsuzuki H
AUTHOR: M Niki M
AUTHOR: H Ueda H
AUTHOR: H Abe H
AUTHOR: Y Kurosu Y
AFFILIATION: Dep. of Surgery, Yokohama Chuo Hospital, Japan.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [Successful combination chemotherapy for a post-operative gastric cancer patient with multiple liver metastases and elevated CEA]
PUBDATE: 19960501
A 75-year-old male was admitted one year after surgery for advanced gastric cancer. He was diagnosed as having multiple liver metastases with elevated serum CEA level. Combination chemotherapy consisting of THP-ADM, MMC and 5'-DFUR was done in the outpatient clinic. As a result, both multiple metastatic liver tumors and serum CEA level showed a remarkable response.

13. DOCID:21565 SCORE: 0.00274694200548948
DOCNO: 7548353
AUTHOR: G Tibblin G
AUTHOR: M Eriksson M
AUTHOR: S Cnattingius S
AUTHOR: A Ekbom A
AFFILIATION: Department of Family Medicine,Uppsala University, Sweden.
PUBTYPE: Journal Article
JOURNALTITLE: Epidemiology (Cambridge, Mass.)
COUNTRY: UNITED STATES
TITLE: High birthweight as a predictor of prostate cancer risk.
PUBDATE: 19950701
In a follow-up study of a cohort of 50-year-old men who were born in 1913 and were living in Gothenburg, Sweden, we found an association between birthweight and prostate cancer. Of 366 men with known birthweight, there were 21 patients with prostate cancer. The incidence is about five times higher in the highest quartile of birthweight than in other birthweight groups. The findings indicate that aspects of the pre- and perinatal period may affect the risk of subsequent prostate cancer.

14. DOCID:18205 SCORE: 0.00271038897154097
DOCNO: 1859330
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Mammography
QUALIFIER: radiography
QUALIFIER: radiography
QUALIFIER: radiography
AUTHOR: L E Albertyn LE
AUTHOR: A C Drew AC
AFFILIATION: Department of Radiology, Queen Elizabeth Hospital, Woodville, South Australia.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Australasian radiology.
COUNTRY: AUSTRALIA
TITLE: Mammographically detected microcalcifications due to pseudoxanthoma elasticum.
PUBDATE: 19910201
Mammographic detection and analysis of microcalcification is a key component in the detection of early breast cancer. A casting configuration or granular morphology has a strong association with malignancy. These are relatively easily recognised, but with the proliferation of mammographic screening, other varieties of calcification are being encountered which may pose diagnostic dilemmas. This case report describes the findings in a patient with Pseudoxanthoma Elasticum (PXE) who presented in this way. To our knowledge, this has not previously been documented. Such calcification is not usually visible on conventional radiographs.