0. DOCID:27075 SCORE: 0.00246432721845022
DOCNO: 10346965
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: isolation & purification
QUALIFIER: isolation & purification
QUALIFIER: chemistry
QUALIFIER: pharmacology
AUTHOR: B S Yun BS
AUTHOR: I J Ryoo IJ
AUTHOR: I K Lee IK
AUTHOR: K H Park KH
AUTHOR: D H Choung DH
AUTHOR: K H Han KH
AUTHOR: I D Yoo ID
AFFILIATION: Korea Research Institute of Bioscience and Biotechnology, P.O. Box 115, Yusong, Taejon 305-600, Korea.
PUBTYPE: Journal Article
JOURNALTITLE: Journal of natural products.
COUNTRY: UNITED STATES
TITLE: Two bioactive pentacyclic triterpene esters from the root bark of Hibiscus syriacus.
PUBDATE: 19990501
Two new triterpene caffeates have been isolated from the root bark of Hibiscus syriacus. Their structures were established through various spectral studies as 3beta,23,28-trihydroxy-12-oleanene 23-caffeate (1) and 3beta,23,28-trihydroxy-12-oleanene 3beta-caffeate (2). Compounds 1 and 2 showed lipid peroxidation inhibitory activity and significant cytotoxicity against a panel of human cancer cell lines.


1. DOCID:27686 SCORE: 0.00225500706165515
DOCNO: 11007144
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: L Gullo L
AUTHOR: R Golfieri R
AUTHOR: G F Orcioni GF
AUTHOR: S Pileri S
AFFILIATION: Department of Internal Medicine and Gastroenterology, University of Bologna, S. Orsola Hospital, Italy.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: European journal of gastroenterology & hepatology.
COUNTRY: ENGLAND
TITLE: Multivisceral eosinophilic fibrosis: a new clinical presentation.
PUBDATE: 20000901
We describe a patient who was referred to us with the diagnosis of pancreatic cancer but who had eosinophilic fibrosis of the pancreas and other organs, including the sub-mandibular salivary glands, retro-orbital tissue, liver, kidneys, and surrounding the abdominal aorta. He had no pain or other symptoms. After treatment with methylprednisolone, all lesions disappeared and now he seems to be cured of this apparently immune-mediated disorder. To our knowledge, involvement of all these particular organs by eosinophilic fibrosis in the absence of symptoms has never before been described.


2. DOCID:27355 SCORE: 0.0022484585651092
DOCNO: 11091918
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: epidemiology
QUALIFIER: epidemiology
QUALIFIER: epidemiology
QUALIFIER: epidemiology
AUTHOR: M B Feinstein MB
AUTHOR: P B Bach PB
AFFILIATION: Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
PUBTYPE: Journal Article
JOURNALTITLE: Chest surgery clinics of North America.
COUNTRY: UNITED STATES
TITLE: Epidemiology of lung cancer.
PUBDATE: 20001101
Lung cancer is the leading cause of cancer mortality in the United States, and its incidence is growing throughout the world. The high morbidity and mortality of lung cancer largely results from the fact that most people are diagnosed with advanced disease, when surgical cures are no longer possible. Although many risk factors have been implicated, the most significant risk for developing lung cancer is clearly tobacco exposure. Tobacco use is currently increasing among specific population groups. It is probable that lung cancer will continue as a major medical and social problem for the foreseeable future.


3. DOCID:26199 SCORE: 0.00211454532513489
DOCNO: 11545544
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Cancer Vaccines
DESCRIPTOR: Dendritic Cells
QUALIFIER: immunology
QUALIFIER: immunology
QUALIFIER: therapy
AUTHOR: G M Sprinzl GM
AUTHOR: L Kacani L
AUTHOR: A Schrott-Fischer A
AUTHOR: N Romani N
AUTHOR: W F Thumfart WF
AFFILIATION: Department of Otorhinolaryngology, Head and Neck Surgery, University of Innsbruck, Austria. georg.sprinzl@uibk.ac.at
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Cancer treatment reviews.
COUNTRY: England
TITLE: Dendritic cell vaccines for cancer therapy.
PUBDATE: 20010801
Dendritic cells (DC) are professional antigen-presenting cells whose primary function is the initiation of immune response. Based on the finding that the immune system usually fails to identify and kill cancer cells, DC have been recently used as vaccines for stimulation of tumour-specific immunity. This review focuses on pitfalls related to DC-based vaccination against solid tumours and on improvement of this immunotherapeutic approach for routine treatment of cancer disease.


4. DOCID:27845 SCORE: 0.00205488809623382
DOCNO: 9794994
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Quality of Life
QUALIFIER: radiotherapy
AUTHOR: C B Scott CB
AFFILIATION: American College of Radiology, Philadelphia, PA 19107, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Seminars in radiation oncology.
COUNTRY: UNITED STATES
TITLE: Issues in quality of life assessment during cancer therapy.
PUBDATE: 19981001
Current treatments for cancer do not differentiate between malignant and normal cells; this limitation results in the adverse effects associated with radiotherapy and chemotherapy. Adverse effects of treatment severely impact the cancer patient's quality of life. Quality of life assessment can help the clinician gauge the efficacy of interventions that reduce the adverse effects of radiotherapy and chemotherapy. Quality of life is an increasingly important outcome measure in the evaluation of cancer treatments, and a variety of tools have been developed for evaluating changes in quality of life. This report reviews several of these measurement tools, focusing primarily on those used in lung cancer trials.


5. DOCID:25035 SCORE: 0.0018310737858157
DOCNO: 10398131
AUTHOR: F T Bosman FT
PUBTYPE: Comment
PUBTYPE: Editorial
JOURNALTITLE: The Journal of pathology.
COUNTRY: ENGLAND
TITLE: The hamartoma-adenoma-carcinoma sequence.
PUBDATE: 19990501
Carcinomas develop, although at low frequency, in hamartomatous polyps in the Peutz-Jeghers' syndrome. With the identification of at least one of the genes involved (LKB1/STK11), attempts can be made to unravel the molecular events responsible for this hamartoma-adenoma-carcinoma sequence. Recent data indicate that this sequence is real, that the molecular pathways involved are different from those in other hereditary colorectal cancer syndromes, and that, possibly in contrast to the hamartomatous polyps in the juvenile polyposis syndrome, the genetic abnormalities occur in the epithelial compartment of the lesions.


6. DOCID:27207 SCORE: 0.00182692994480329
DOCNO: 9799956
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: etiology
AUTHOR: U Ringborg U
AFFILIATION: Department of Oncology, Radiumhemmet, Stockholm, Sweden.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Alcoholism, clinical and experimental research.
COUNTRY: UNITED STATES
TITLE: Alcohol and risk of cancer.
PUBDATE: 19981001
A large number of cohort and case-control studies have contributed to increased knowledge regarding alcoholic beverages and risk of malignant diseases. A clear association pointing at a causal relationship has been found for cancer of the oral cavity, pharynx, larynx, esophagus, and liver. A suggestive association has been found for cancer of the large bowel and breast. An association is considered unlikely for cancer of the stomach, pancreas, lung, urinary bladder, prostate, ovary, and for malignant melanoma. Studies have also been conducted regarding endometrial cancer, kidney cancer, leukemia, and lymphoma. No associations have been demonstrated, but the number of studies is too small for conclusions.


7. DOCID:27478 SCORE: 0.00182164238516807
DOCNO: 10485192
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Aged
DESCRIPTOR: Palliative Care
AUTHOR: S Lefebvre-Chapiro S
AUTHOR: R Sebag-Lanoë R
AFFILIATION: Service de gérontologie et de soins palliatifs, Hôpital Paul-Brousse, Villejuif.
PUBTYPE: Journal Article
JOURNALTITLE: La Revue du praticien.
COUNTRY: FRANCE
TITLE: [Palliative care of the aged]
PUBDATE: 19990501
Palliative care is no longer limited to patients with terminal cancer but now includes other diseases at terminal stage such as advanced Alzheimer disease. Accompanying the elderly at the end of life involves medical, psychological and social approaches. The expression of symptoms, and especially that of pain, can be atypical. Medical prescription should take into account both the change in drug metabolism and the more frequent occurrence of side effects in the elderly. Accompanying the patient at the end of life is an increasing part of care in geriatric institutions. Indispensable factors today are adapted personnel, training, specific support and social actualization.


8. DOCID:27909 SCORE: 0.00175566933459848
DOCNO: 11116875
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Sexual Dysfunction, Physiological
DESCRIPTOR: Sexual Dysfunctions, Psychological
DESCRIPTOR: Sexuality
QUALIFIER: psychology
AUTHOR: K Bergmark K
AUTHOR: E A Lundqvist EA
AUTHOR: G Steineck G
AFFILIATION: Sektionen för gynekologisk onkologi, Radiumhemmet samt forskargruppen klinisk cancerepidemiologi. Karin.Bergmark@onkpat.ki.se
PUBTYPE: Journal Article
JOURNALTITLE: Läkartidningen.
COUNTRY: Sweden
TITLE: [A Swedish study of women treated for cervix cancer. Gynecologic cancer often affects sexuality]
PUBDATE: 20001101
Gynecological cancer and its treatments are often associated with physical, psychological and social consequences that affect the woman's and the couple's sexuality. Especially due to their impact on sexuality, physical changes distress the women considerably, and warrant consideration for women of all ages. Women with gynecological cancer ask for information about possible side-effects of the disease and treatment that can affect the sexual function. At follow-up visits these issues can be attended to through information, with specific suggestions including advice about topical estrogen and dilators, to alleviate possible long-term sequelae.


9. DOCID:25839 SCORE: 0.00174836599033983
DOCNO: 9894777
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Ambulatory Surgical Procedures
QUALIFIER: surgery
AUTHOR: F M Sega FM
AUTHOR: A S Catalani AS
AFFILIATION: Regina Elena Cancer Institute, Rome, Italy.
PUBTYPE: Journal Article
JOURNALTITLE: Journal of experimental & clinical cancer research : CR.
COUNTRY: ITALY
TITLE: Day-surgery. The "Regina Elena" National Cancer Institute experience.
PUBDATE: 19980901
The Authors thorough analyse the subject of day-surgery underscoring the advantages this procedure represents in the light of the experience gained at "R.Elena" National Cancer Institute. The aims of ambulatorial surgery are, in broad terms, the safety of procedures, patients' compliance as well as organisational and economic savings for the health structure. In the future, one-day surgery might represent an important contribution to surgical therapeutical strategies allowing, if well organized, an excellent compromise between safety, convenience and reduced costs.


10. DOCID:26065 SCORE: 0.0017294880742007
DOCNO: 10738997
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Bone Marrow Transplantation
QUALIFIER: prevention & control
QUALIFIER: isolation & purification
QUALIFIER: prevention & control
QUALIFIER: therapy
AUTHOR: H Hanna H
AUTHOR: I Raad I
AUTHOR: V Gonzalez V
AUTHOR: J Umphrey J
AUTHOR: J Tarrand J
AUTHOR: J Neumann J
AUTHOR: R Champlin R
AFFILIATION: Section of Infectious Diseases, University of Texas MD Anderson Cancer Center, Houston 77030, USA.
PUBTYPE: Journal Article
JOURNALTITLE: Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America.
COUNTRY: UNITED STATES
TITLE: Control of nosocomial Clostridium difficile transmission in bone marrow transplant patients.
PUBDATE: 20000301
This is a report of six cases of Clostridium difficile-associated diarrhea (CDAD) that occurred among cancer patients undergoing bone marrow transplantation in a tertiary-care cancer hospital. Specific infection control measures that were taken to minimize the nosocomial spread of CDAD also are discussed.


11. DOCID:27612 SCORE: 0.00167163677302059
DOCNO: 9749881
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: physiopathology
QUALIFIER: physiology
AUTHOR: B K Vonderhaar BK
AFFILIATION: Molecular and Cellular Endocrinology Section, Laboratory of Tumor Immunology and Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Pharmacology & therapeutics.
COUNTRY: ENGLAND
TITLE: Prolactin: the forgotten hormone of human breast cancer.
PUBDATE: 19980801
Prolactin (PRL) is both a mitogen and a differentiating agent in the mammary gland. It has been shown to be involved in mammary cancer development in rodents, but in human breast cancer, its role has long been overlooked. Three criteria are applied to demonstrate PRL's involvement in this disease: (1) PRL receptors are present in human breast cancer cells, (2) human breast cancer cells in culture respond to PRL as a mitogen, and (3) PRL is synthesized by human breast cancer cells and inhibition of the binding of PRL to its receptors inhibits cell growth.


12. DOCID:26218 SCORE: 0.00163740039787083
DOCNO: 10967749
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: epidemiology
QUALIFIER: epidemiology
QUALIFIER: epidemiology
AUTHOR: Z Gamliel Z
AFFILIATION: Division of Thoracic Surgery, Greenebaum Cancer Center, University of Maryland Medical Center, Baltimore, Maryland, USA. zgamliel@smail.umaryland.edu
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Chest surgery clinics of North America.
COUNTRY: UNITED STATES
TITLE: Incidence, epidemiology, and etiology of esophageal cancer.
PUBDATE: 20000801
The precise causes of esophageal cancer have not been identified. A number of carcinogens and predisposing conditions have been implicated. There are pronounced differences between the demographic groups affected by squamous cell carcinoma and adenocarcinoma of the esophagus. Whereas the incidence of squamous cell carcinoma has remained constant, the incidence of adenocarcinoma of the esophagus has been rising steadily in recent years. The reasons for this trend remain unclear. Further studies of the molecular biology and epidemiology of this disease are needed.


13. DOCID:24530 SCORE: 0.0016316490362398
DOCNO: 11586410
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: radiation effects
QUALIFIER: pathology
QUALIFIER: radiotherapy
AUTHOR: A I Kolesnikova AI
AUTHOR: N I Sychenkova NI
AUTHOR: A G Konoplyannikov AG
AUTHOR: L A Lepekhina LA
AUTHOR: S S Kal'sina SS
AUTHOR: L I Krikunova LI
AUTHOR: Y S Mardynskii YS
AFFILIATION: Medical Research Center for Radiology, Russian Academy of Medical Sciences, Obninsk.
PUBTYPE: Journal Article
JOURNALTITLE: Bulletin of experimental biology and medicine.
COUNTRY: United States
TITLE: Effect of irradiation on colony-forming ability of stem cells from patients with ovarian cancer.
PUBDATE: 20010601
In patients with ovarian cancer, the colony-forming capacity and radiosensitivity of clonogenic tumor cells from the primary node and metastases (ascites) differed considerably.


14. DOCID:24952 SCORE: 0.00160612151607677
DOCNO: 9689882
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Economics, Pharmaceutical
QUALIFIER: economics
QUALIFIER: drug therapy
QUALIFIER: drug therapy
AUTHOR: G Jerusalem G
AUTHOR: V Bours V
AUTHOR: G Fillet G
AFFILIATION: Département de Médecine, Université de Liège.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Revue médicale de Liège.
COUNTRY: BELGIUM
TITLE: [Treatment of colorectal cancer. Pharmaco-economic aspects]
PUBDATE: 19980501
Cancer patients care is mainly based on scientific studies, but sometimes approaches are empiric. Rapid growth of health care expenses force the physician to take pharmacoeconomic aspects into consideration. New clinical studies have to analyse clinical benefits but also cost-effectiveness. We will review the various aspects of colorectal cancer from primary prevention to post-treatment follow-up. Scientific data are integrated in a pharmacoeconomic analysis.