0. DOCID:7072 SCORE: 0.00287408838690663
DOCNO: 760187
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: diagnosis
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: R Killer-Walser R
AUTHOR: H Hess H
AUTHOR: T G Würsch TG
AUTHOR: K Stuby K
AUTHOR: A Sonnenberg A
AUTHOR: W Brühlmann W
AUTHOR: A L Blum AL
PUBTYPE: Journal Article
JOURNALTITLE: Schweizerische medizinische Wochenschrift.
COUNTRY: SWITZERLAND
TITLE: [Fiber endoscopy and radiology in stomach ulcer, stomach neoplasms and hiatal hernia: questions, timing and value]
PUBDATE: 19790101
In 306 patients, fiberpanendoscopy and radiology were performed within a time interval of 7 days or less. In 196 cases, radiology was performed before endoscopy and in 110 cases after endoscopy. In cases with histologically unproven divergent findings, follow-up studies were performed. In the diagnosis of gastric ulcer and gastric cancer, endoscopy with biopsy was more accurate than radiology. In the diagnosis of hiatal hernia, radiology was more accurate. Important additional findings difficult or impossible to observe with endoscopy were present in 36% of the radiological examinations. Thus, the first examination should be endoscopy when ulcer or carcinoma is suspected. In patients with uncharacteristic epigastric symptoms, radiology should be performed first.

1. DOCID:7855 SCORE: 0.00278334834466423
DOCNO: 582494
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Food Habits
DESCRIPTOR: Vitamin A
QUALIFIER: etiology
AUTHOR: C Mettlin C
AUTHOR: S Graham S
PUBTYPE: Journal Article
JOURNALTITLE: American journal of epidemiology.
COUNTRY: UNITED STATES
TITLE: Dietary risk factors in human bladder cancer.
PUBDATE: 19790901
Retrospective data on dietary habits, employment history and tobacco use were obtained from 569 bladder cancer patients and 1025 age-matched controls admitted to Roswell Park Memorial Institute. Sex-adjusted relative risks revealed increases in risk for lower levels of an index of vitamin A intake. A similar pattern of risk elevation was associated with infrequent milk and carrot intake. Some elevation of risk was found for heavy coffee drinking but the apparent protective effect for milk consumption was not found to be a spurious result of lower coffee intake. Neither was the role of vitamin A explained by its relationship with smoking or employment in high risk occupations. Some association of bladder cancer with infrequent consumption of cruciferous vegetables was also observed. The findings of this investigation are consistent with tumor inhibition by retinoids in animal studies and the low risk associated with vitamin A in epidemiologic studies of lung cancer.

2. DOCID:7724 SCORE: 0.0025962249776749
DOCNO: 464805
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Ultrasonography
QUALIFIER: prevention & control
QUALIFIER: analysis
QUALIFIER: prevention & control
AUTHOR: C R Mackie CR
AUTHOR: J Bowie J
AUTHOR: M J Cooper MJ
AUTHOR: M H Lewis MH
AUTHOR: A R Moossa AR
PUBTYPE: Journal Article
JOURNALTITLE: Archives of surgery (Chicago, Ill. : 1960)
COUNTRY: UNITED STATES
TITLE: Ultrasonography and tumor-associated antigens. The concept of combining noninvasive tests in the screening for pancreatic cancer.
PUBDATE: 19790801
A total of 134 patients suspected of having pancreatic cancer were given preoperative ultrasonic examinations. A total of 54 cases had a final diagnosis of pancreatic cancer histologically confirmed. The diagnostic sensitivity and specificity of the ultrasonographies were 76% and 91% or 87% and 74%, depending on whether doubtful results were called abnormal or normal. "Doubtful" results were defined as those that stated that pancreatic cancer was "possible" or "could not be excluded." When these results were divided into abnormal and normal groups on the basis of the patients' preoperative serum carcinoembryonic antigen and pancreatic oncofetal antigen levels, the sensitivity and specificity of the combined tests may prove to be a more accurate means of screening patients for pancreatic cancer than ultrasonography alone.

3. DOCID:5265 SCORE: 0.00247049859280808
DOCNO: 7379661
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Age Factors
QUALIFIER: epidemiology
AUTHOR: I L Horovitz IL
AUTHOR: M Huber M
PUBTYPE: Journal Article
JOURNALTITLE: Diseases of the colon and rectum.
COUNTRY: UNITED STATES
TITLE: Cancer of the colon: a study of age-related incidence.
PUBDATE: 19800301
Incidence of colorectal cancer in Israel was studied in 1035 patients who were divided by ethno-geography into a Euro-American group and an Afro-Asian group. The majority of patients were in the age groups over 50 years, with a markedly higher incidence rate of disease in the Euro-American group. In the younger age group the incidence rate of the disease was significantly higher in the Afro-Asian group. These findings, if verified by others, must lead to revision of our present concepts of epidemiology of colorectal cancer.

4. DOCID:4464 SCORE: 0.00228738509547606
DOCNO: 417987
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
AUTHOR: R Schrage R
PUBTYPE: Journal Article
JOURNALTITLE: Fortschritte der Medizin.
COUNTRY: GERMANY, WEST
TITLE: [Problems of current diagnosis of neoplasms in women]
PUBDATE: 19780501
The value of early cancer detection in women is limited by the screening methods and their minor reliability in "mass-screening". The effect of detection programs is difficult to demonstrate. The interest in cancer detection is low, especially in elderly high risk patients. A more suitable application of screening tests with widespread indication of further methods together with exact demonstration could be the basis for better results in early cancer detection programs in women.

5. DOCID:7689 SCORE: 0.00193782245887808
DOCNO: 746104
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Adaptation, Psychological
DESCRIPTOR: Ego
QUALIFIER: psychology
AUTHOR: J W Worden JW
AUTHOR: H J Sobel HJ
PUBTYPE: Journal Article
JOURNALTITLE: Psychosomatic medicine.
COUNTRY: UNITED STATES
TITLE: Ego strength and psychosocial adaptation to cancer.
PUBDATE: 19781201
This study investigated a patient's ego strength (Es) at the time of an initial cancer diagnosis and its relationship, over time, to mood disturbance, vulnerability, self-reported physical symptom totals, current concerns, coping strategies, and effectiveness in the resolution of problems. The subjects were 163 newly diagnosed male and female cancer patients representing five primary tumor sites. All patients were seen for an initial evaluation, at which time they completed Barron's Es scale, the Profile of Mood States, the Inventory of Current Concerns, and a semistructured interview. Ratings on patient vulnerability, coping strategies, and problem resolutions were made at each of the five follow-ups. Results showed that psychosocial adaptation to cancer was related to a patient's ego strength. Es correlated positively with a patient's use of effective coping strategies. The concept of Es and problems with Es assessment were discussed within a cognitive-ego analytic frame of reference.

6. DOCID:7808 SCORE: 0.00187010365853572
DOCNO: 6447114
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Lymphocyte Activation
QUALIFIER: immunology
QUALIFIER: immunology
QUALIFIER: immunology
QUALIFIER: immunology
QUALIFIER: immunology
AUTHOR: G B Cannon GB
AUTHOR: J H Dean JH
AUTHOR: R B Herberman RB
AUTHOR: E Perlin E
AUTHOR: J Reid J
AUTHOR: C Miller C
AUTHOR: N P Lang NP
PUBTYPE: Journal Article
JOURNALTITLE: International journal of cancer. Journal international du cancer.
COUNTRY: DENMARK
TITLE: Association of depressed postoperative lymphoproliferative responses to alloantigens with poor prognosis in patients with stage I lung cancer.
PUBDATE: 19800101
Thirty-five patients with Stage I carcinoma of the lung were tested postoperatively to assess lymphoproliferative responses. Depressed lymphocyte proliferation (LP) responses to alloantaigen in the mixed leukocyte culture (MLC) as measured by thee relative proliferation index (RPI) were associated with a significantly shorter disease-free interval. In this group of patients, the immunologic responses predicted subsequent clinical course better than the TNM classification or the histological type of the tumor, and therefore this procedure appears promising for improved staging of patients with early stages of lung cancer (stage I lung cancer and T1N0M0). The depressed response to alloantaigen was a more sensitive discriminator of disease recurrence than PHA alone or even conbined with PHA.

7. DOCID:7725 SCORE: 0.00175833617554675
DOCNO: 464624
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: complications
QUALIFIER: complications
AUTHOR: S C Duncan SC
AUTHOR: R K Winkelmann RK
PUBTYPE: Journal Article
JOURNALTITLE: Archives of dermatology.
COUNTRY: UNITED STATES
TITLE: Cancer and scleroderma.
PUBDATE: 19790801
Of 2,141 patients with scleroderma who were seen at the Mayo Clinic, Rochester, Minn, between 1959 and 1975, 78 had 87 internal malignancies. The relative frequency of the types of cancers was similar to that for the general population. The increased numbers of patients with breast and uterine carcinomas were consistent with the female preponderance in scleroderma. Contrary to previous reports, carcinoma of the lung was not the most frequent malignancy associated with scleroderma. The lymphoma-leukemia malignancies were second only to breast carcinoma in frequency, comprising about 17% of the malignancies. Both conditions developed within a three-year period in 68% (45/66) of our patients affected with systemic scleroderma, and this subgroup comprised a high mortality group. This study is not an epidemiologic one in the strictest sense, but it is a review of the experience of the Mayo Clinic with patients who have had both scleroderma and an internal malignancy.

8. DOCID:6558 SCORE: 0.00174445051027298
DOCNO: 754607
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: L Texier L
AUTHOR: M Géniaux M
AUTHOR: J M Tamisier JM
AUTHOR: M M Delaunay MM
AUTHOR: C Plante C
PUBTYPE: Journal Article
JOURNALTITLE: Annales de dermatologie et de vénéréologie.
COUNTRY: FRANCE
TITLE: [Cutaneous metastases in digestive cancers (author's transl)]
PUBDATE: 19781101
Cutaneous metastases are seldom encountered in digestive cancers. The mechanism of their formation explains their low rate. The metastases spread mainly by the lymphatic system (especially in diffuse, spotty or pseudo-elephantiasic forms and in regional forms), however numerous lymph node filters found through out the lymphatic system limit the progression of neoplasic cells. On the contrary, metastases most often spread by retrograde involvement due to blocking of the lymphatic system. As for hematogenous metastases (generalized nodular forms or aberrant localizations), they are observed even less frequently than lymphatic ones; metastatic embolisms may effectively become blocked in capillaries, especially in the lungs and the liver, which constitutes a double barrier before the skin may be involved.

9. DOCID:6073 SCORE: 0.0016860148369284
DOCNO: 310475
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Rosette Formation
QUALIFIER: immunology
QUALIFIER: immunology
AUTHOR: G Carmignani G
AUTHOR: E Belgrano E
AUTHOR: P Puppo P
AUTHOR: P Cornaglia P
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of urology.
COUNTRY: UNITED STATES
TITLE: T lymphocytes inhibiting factors in renal cancer: evaluation of differences between arterial and renal venous blood levels of E rosette forming cells.
PUBDATE: 19781201
The cellular immune response has been reported to be impaired in patients with renal cancer and to be increased by removal of the tumor bulk. T lymphocyte levels in the vein of the neoplastic kidney were investigated in 4 patients to assess the presence of a T lymphocyte inhibiting factor produced by the tumor. T lymphocyte levels resulted in significantly decreased tumorous venous blood, whether compared to arterial, contralateral or peripheral blood. A similar result was not found in 10 control patients. Some hypotheses on the nature of this T lymphocyte inhibition are discussed.

10. DOCID:6241 SCORE: 0.00168504922733348
DOCNO: 6773888
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: chemically induced
QUALIFIER: drug therapy
QUALIFIER: physiopathology
AUTHOR: S D Fosså SD
AUTHOR: O Klepp O
AUTHOR: A Aakvaag A
AUTHOR: K Molne K
PUBTYPE: Journal Article
JOURNALTITLE: International journal of andrology.
COUNTRY: DENMARK
TITLE: Testicular function after combined chemotherapy for metastatic testicular cancer.
PUBDATE: 19800201
In 10 patients cured for metastatic testicular cancer by combination chemotherapy serum hormone levels and serum agglutinating antibodies were analysed 12 to 35 months after discontinuation of the treatment. Together with these examinations sperm analysis was done. All patients had increased levels of follicle stimulating hormone (FSH). Serum testosterone was usually in the lower part of the normal range (below 20 nmol/l). In eight patients the serum agglutinating antibodies were normal, while two patients had increased levels. In all patients azoospermia was observed, indicating long-lasting infertility in patients testicular cancer treated by combination chemotherapy. The possible importance of cryopreservation prior to start of chemotherapy is discussed.

11. DOCID:4848 SCORE: 0.0016763055854348
DOCNO: 710884
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: therapy
QUALIFIER: pathology
QUALIFIER: etiology
AUTHOR: H Mertens H
AUTHOR: W Jonat W
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Geburtshilfe und Frauenheilkunde.
COUNTRY: GERMANY, WEST
TITLE: [Bilateral carcinoma of the breast after radiotherapy and chemotherapy for Hodgkin's disease (author's transl)]
PUBDATE: 19781101
A 34-year-old patient had radiotherapy and chemotherapy for Hodgkin's disease of the nodular sclerosing type 2 A thirteen years prior to the treatment of a right cancer of the breast in the stage M0 N1 T3. Seven months later the patient had a left cancer of the breast in the stage M0 N0 T4. The literature is reviewed and the possibility of occurrance of secondary carcinoma following treatment of Hodgkin's disease is discussed.

12. DOCID:7665 SCORE: 0.00167175945651757
DOCNO: 6108167
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analysis
QUALIFIER: analysis
QUALIFIER: analysis
QUALIFIER: analysis
QUALIFIER: analysis
QUALIFIER: analysis
AUTHOR: D D Munjal DD
PUBTYPE: Journal Article
JOURNALTITLE: Clinical chemistry.
COUNTRY: UNITED STATES
TITLE: Concurrent measurements of carcinoembryonic antigen, glucosephosphate isomerase, gamma-glutamyltransferase, and lactate dehydrogenase in malignant, normal adult, and fetal colon tissues.
PUBDATE: 19801201
Carcinoembryonic antigen and activities of glucosephosphate isomerase (EC 5.3.1.9), gamma-glutamyltransferase (EC 2.3.2.2), and lactate dehydrogenase (EC 1.1.1.27) were measured in aqueous extracts of fetal, normal adult, and malignant human colon tissues. Fetal colon, as well as primary and metastatic colon tumor tissue, showed higher activities of these analytes than did normal adult human colon. Liver metastases of colon cancer gave the highest values, normal adult human colon the lowest. Statistically, these differences were more striking in the case of carcinoembryonic antigen and glucosephosphate isomerase than for gamma-glutamyltransferase or lactate dehydrogenase. In contrast to the other markers, gamma-glutamyltransferase activity was lower in fetal organs than in normal adult colon and colon tumors. These results are consistent with earlier observations that activities of these markers are significantly increased in the blood of patients with metastatic colon cancer.

13. DOCID:5218 SCORE: 0.00167056858369531
DOCNO: 7240623
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: diagnosis
QUALIFIER: diagnosis
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: P S Shankar PS
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Journal of the American Geriatrics Society.
COUNTRY: UNITED STATES
TITLE: Synchronous dual primary lung carcinomas.
PUBDATE: 19810701
Synchronous dual primary lung carcinomas were found in 8 of 482 patients with lung cancer, an incidence of 1.6 percent. Of the 8 cases, 7 were unilateral and one bilateral. Three showed dissimilar histologic patterns occurring in combinations of squamous-cell carcinoma and adenocarcinoma. In 5 cases, two separate tumors were noted with identical histologic patterns in combinations of squamous-cell, giant-cell, large-cell, adeno-. and undifferentiated carcinoma. The patients were heavy smokers and this possibly may have been a factor in the development of carcinoma at more than one site.

14. DOCID:7936 SCORE: 0.00161814632940143
DOCNO: 7299084
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Counseling
QUALIFIER: psychology
AUTHOR: B S Linn BS
AUTHOR: M W Linn MW
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
PUBTYPE: Randomized Controlled Trial
JOURNALTITLE: Journal of gerontology.
COUNTRY: UNITED STATES
TITLE: Late stage cancer patients: age differences in their psychophysical status and response to counseling.
PUBDATE: 19811101
Much has been written about working with dying patients. To evaluate counseling, 120 terminally ill cancer patients were randomly assigned to counseling or no counseling and studied before random assignment and at 1, 3, 6, 9, and 12 months on quality of life variables (alienation, depression, locus of control, life satisfaction, self-esteem) as well as functional status and survival. Counseled patients changed significantly in comparison to controls and in a favorable direction by 3 months. The purpose here was to see if older and younger cancer patients differed at baseline and if outcomes of counseling differed by age. Patients under age 60 were compared with those 60 and over. There was no multivariate difference at baseline but univariate differences of more disability and less life satisfaction in the older group. Overall, response to therapy was similar in old and young, with both improving.