0. DOCID:29337 SCORE: 0.0030955967561268
DOCNO: 16474761
OWNER: NLM
STATUS: In-Data-Review
AUTHOR: Michael W Kattan MW
AFFILIATION: MW Kattan is Chairman of the Department of Quantitative Health Sciences at the Cleveland Clinic Foundation, OH, USA.
PUBTYPE: Journal Article
JOURNALTITLE: Nature clinical practice. Urology.
COUNTRY: United States
TITLE: When and how to use informatics tools in caring for urologic patients.
PUBDATE: 20050401
Making predictions is an essential part of any medical decision. It is particularly crucial when considering treatment of clinically localized prostate cancer. Nomograms and prediction model software typically provide the most accurate predictions. Many nomograms have been developed, for all prostate cancer clinical states. Some of these are discussed in this review, as is their utility in facilitating decision making and informed consent.


1. DOCID:28879 SCORE: 0.00309557839384329
DOCNO: 16354327
OWNER: NLM
STATUS: In-Process
AUTHOR: Luciano Wannesson L
AUTHOR: Franco Cavalli F
AUTHOR: Emmanuele Zucca E
AFFILIATION: Department of Medical Oncology, Institute of Southern Switzerland, Bellinzona, Switzerland.
PUBTYPE: Journal Article
JOURNALTITLE: Clinical lymphoma & myeloma.
COUNTRY: United States
TITLE: Primary pulmonary lymphoma: current status.
PUBDATE: 20051101
Primary pulmonary lymphoma (PPL) is a rare disease with a favorable prognosis compared with lung cancer. Although a number of histologic variables of B- and T-cell lymphoma were reported as PPL, marginal zone lymphoma of the mucosa-associated lymphoid tissue type is by far the most frequent diagnosis. This review summarizes the present knowledge of histopathology, molecular biology, diagnosis, prognosis, and treatment of this heterogeneous entity.


2. DOCID:27930 SCORE: 0.00250931975675797
DOCNO: 10683075
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: diagnosis
QUALIFIER: etiology
QUALIFIER: diagnosis
AUTHOR: B D Keith BD
AUTHOR: V H Bramwell VH
AFFILIATION: London Regional Cancer Center, Ontario, Canada.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: American journal of clinical oncology : the official publication of the American Radium Society.
COUNTRY: UNITED STATES
TITLE: Pyomyositis after chemotherapy for breast cancer.
PUBDATE: 20000201
Pyomyositis is a rare complication of chemotherapy. A 47-year-old woman with metastatic breast cancer, in whom pyomyositis developed after chemotherapy, is described. It was difficult to differentiate between pyomyositis and deep venous thrombosis early in her admission. Pyomyositis should be considered part of the differential diagnosis of deep venous thrombosis. This infection, after chemotherapy, usually is considered to be caused by neutropenia or immunodeficiency secondary to the cancer, or both. It is postulated that subclinical myopathy, secondary to the malignancy or drugs used in treating the malignancy, or both, may also predispose to pyomyositis.


3. DOCID:26031 SCORE: 0.00243883814228418
DOCNO: 11484991
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
QUALIFIER: therapeutic use
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
QUALIFIER: therapeutic use
AUTHOR: Y Michiwa Y
AUTHOR: M Earashi M
AUTHOR: H Kobayashi H
AUTHOR: N Matsuki N
AFFILIATION: Dept. of Surgery, Toyama Rosai Hospital, Uozu, Japan. surgery@keiju.co.jp
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Journal of experimental & clinical cancer research : CR.
COUNTRY: Italy
TITLE: Cutaneous metastases from gastric adenocarcinoma treated with combination chemotherapy producing complete response with long survival.
PUBDATE: 20010601
A case of cutaneous metastases from gastric adenocarcinoma was presented. It was treated with combination chemotherapy producing complete response with prolongation of survival. Skin metastasis will indicate early fatal termination, therefore there has not yet been a reported case of cutaneous metastasis from gastric cancer to have complete response with long survival.


4. DOCID:27614 SCORE: 0.00216291124647127
DOCNO: 9721090
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Apoptosis
AUTHOR: G Evan G
AUTHOR: T Littlewood T
AFFILIATION: Imperial Cancer Research Fund Laboratories, 44, Lincoln's Inn Fields, London WC2A 3PX, UK.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Science.
COUNTRY: UNITED STATES
TITLE: A matter of life and cell death.
PUBDATE: 19980801
In multicellular organisms, mutations in somatic cells affecting critical genes that regulate cell proliferation and survival cause fatal cancers. Repair of the damage is one obvious option, although the relative inconsequence of individual cells in metazoans means that it is often a "safer" strategy to ablate the offending cell. Not surprisingly, corruption of the machinery that senses or implements DNA damage greatly predisposes to cancer. Nonetheless, even when oncogenic mutations do occur, there exist potent mechanisms that limit the expansion of affected cells by suppressing their proliferation or triggering their suicide. Growing understanding of these innate mechanisms is suggesting novel therapeutic strategies for cancer.


5. DOCID:29784 SCORE: 0.00208402315740498
DOCNO: 15841168
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: genetics
QUALIFIER: therapy
QUALIFIER: genetics
QUALIFIER: therapy
AUTHOR: Yakov Chudnovsky Y
AUTHOR: Paul A Khavari PA
AUTHOR: Amy E Adams AE
AFFILIATION: Veterans Affairs Palo Alto Healthcare System, Palo Alto, California, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The Journal of clinical investigation.
COUNTRY: United States
TITLE: Melanoma genetics and the development of rational therapeutics.
PUBDATE: 20050401
Melanoma is a cancer of the neural crest-derived cells that provide pigmentation to skin and other tissues. Over the past 4 decades, the incidence of melanoma has increased more rapidly than that of any other malignancy in the United States. No current treatments substantially enhance patient survival once metastasis has occurred. This review focuses on recent insights into melanoma genetics and new therapeutic approaches being developed based on these advances.


6. DOCID:27579 SCORE: 0.00204997736300125
DOCNO: 10674986
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analysis
QUALIFIER: immunology
QUALIFIER: analysis
QUALIFIER: immunology
QUALIFIER: immunology
AUTHOR: T Kikuchi T
AUTHOR: J Arai J
AUTHOR: H Shibuki H
AUTHOR: H Kawashima H
AUTHOR: N Yoshimura N
AFFILIATION: Department of Ophthalmology, Shinshu University School of Medicine, Matsumoto, Japan.
PUBTYPE: Journal Article
JOURNALTITLE: Journal of neuroimmunology.
COUNTRY: NETHERLANDS
TITLE: Tubby-like protein 1 as an autoantigen in cancer-associated retinopathy.
PUBDATE: 20000201
Cancer-associated retinopathy (CAR) is a rare paraneoplastic syndrome that is characterized by retinal degeneration. Two cDNA clones, recoverin and tubby-like protein 1 (TULP1), were isolated from a human retinal cDNA library by using serum from a CAR patient as the probe. Both recoverin and TULP1 are retina-specific protein, and TULP1 is a member of tubby gene family. A determination of the recognized amino acid sequence of TULP1 by the patient serum and immunohistochemical studies on the distribution of TULP1 in the retina were done in this study.


7. DOCID:25011 SCORE: 0.00194932745809621
DOCNO: 11677125
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: chemistry
QUALIFIER: chemical synthesis
QUALIFIER: analogs & derivatives
QUALIFIER: chemistry
QUALIFIER: chemistry
QUALIFIER: chemistry
AUTHOR: Y Xie Y
AUTHOR: M D Short MD
AUTHOR: P B Cassidy PB
AUTHOR: J C Roberts JC
AFFILIATION: Department of Medicinal Chemistry, University of Utah, Salt Lake City, UT 84112, USA.
PUBTYPE: Journal Article
JOURNALTITLE: Bioorganic & medicinal chemistry letters.
COUNTRY: England
TITLE: Selenazolidines as novel organoselenium delivery agents.
PUBDATE: 20011101
Two new classes of selenazolidine-4(R)-carboxylic acids (2-oxo and 2-methyl-SCAs) were synthesized and characterized. Both were designed as latent forms of selenocysteine, intended to provide a chemically superior delivery form for selenium. The prodrugs may be clinically useful when selenium supplementation at supranutritional levels is indicated, such as in cancer chemoprevention.


8. DOCID:26205 SCORE: 0.00192313492109986
DOCNO: 11355914
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: epidemiology
QUALIFIER: diagnosis
QUALIFIER: epidemiology
AUTHOR: H Messmann H
AFFILIATION: Department of Internal Medicine I, University of Regensburg, Germany.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Best practice & research. Clinical gastroenterology.
COUNTRY: England
TITLE: Squamous cell cancer of the oesophagus.
PUBDATE: 20010401
Squamous cell cancer is the most common neoplasm of the oesophagus worldwide, with an enormous variation in its global incidence. Several risk factors, such as achalasia, Plummer-Vinson syndrome, coeliac disease and nutritional factors, have been identified. The surveillance of patients, especially those with tylosis or caustic ingestion, has been recommended. Vital staining with iodine may improve the diagnosis of early cancer. The endoscopic management of early cancer and dysplasia by minimal invasive techniques such as photodynamic therapy or mucosal resection has become attractive for many of these patients with co-morbidity.


9. DOCID:31496 SCORE: 0.0017791893615121
DOCNO: 15991629
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: Khalil Zaman K
AUTHOR: Nicholas Ketterer N
AUTHOR: Diane Vulliémoz D
AUTHOR: Roger Stupp R
AUTHOR: Serge Leyvraz S
AFFILIATION: Fondation du Centre pluridisciplinaire d'oncologie, CHUV, 1011 Lausanne. Khalil.Zaman@hospvd.ch
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Revue médicale suisse.
COUNTRY: Switzerland
TITLE: [New systemic therapies in oncology]
PUBDATE: 20050501
These last decades showed important progress in cancer systemic therapies. A better understanding of the differences between cancer cells and normal cells lead to the emergence of targeted therapies. These treatments interfere with different specific molecules playing a critical role in tumour growth or progression. On the other side, thanks to the development of new therapeutic substances, new modes of administration and to the improvement of supportive care, conventional chemotherapy is more effective and less toxic. The following review summarizes current progress with clinical impact observed these last years.


10. DOCID:28891 SCORE: 0.00174204263990916
DOCNO: 15211821
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: metabolism
QUALIFIER: epidemiology
AUTHOR: Junfang Wang J
AUTHOR: Chengyu Huang C
AUTHOR: Sihan Li S
AFFILIATION: Huaxi School of Public Health, Sichuan University, Chengdu 610041, China.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Wei sheng yan jiu = Journal of hygiene research.
COUNTRY: China
TITLE: [Research progress on dietary fat and the development of lung cancer]
PUBDATE: 20040501
The epidemiological studies showed close relations between dietary fat and lung cancer, but large gaps still exist in understanding. There were no mechanical indications to confirm some conclusions. In this paper, the possible mechanisms including imbalance of fatty acid ratios, insulin resistance, lipids peroxidation, endocrine mechanism, cytokine abnormality and membrane fluidity changes were reviewed.


11. DOCID:30579 SCORE: 0.00171709121623254
DOCNO: 16266579
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: trends
AUTHOR: Ole Kronborg O
AFFILIATION: Odense Universitetshospital, Kirurgisk Afdeling A. ole.kronborg@dadlnet.dk
PUBTYPE: Journal Article
JOURNALTITLE: Ugeskrift for laeger.
COUNTRY: Denmark
TITLE: [Future perspectives in screening for colorectal cancer]
PUBDATE: 20051001
Based on international experience, pilot studies with fecal occult blood tests and colonoscopy in those with blood in the stools are now to be performed in Scandinavia in limited geographic areas before introducing countrywide screening. The Danish State has offered to pay for feasibility studies in two counties. Provided that the results of randomised clinical trials are reproduced according to acceptability and stage of the cancer found and the organisation is feasible, it will then be possible to evaluate newer technologies as well as other methods which have not previously been evaluated in a satisfactory way.


12. DOCID:30481 SCORE: 0.00171708828661897
DOCNO: 16266579
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: trends
AUTHOR: Ole Kronborg O
AFFILIATION: Odense Universitetshospital, Kirurgisk Afdeling A. ole.kronborg@dadlnet.dk
PUBTYPE: Journal Article
JOURNALTITLE: Ugeskrift for laeger.
COUNTRY: Denmark
TITLE: [Future perspectives in screening for colorectal cancer]
PUBDATE: 20051001
Based on international experience, pilot studies with fecal occult blood tests and colonoscopy in those with blood in the stools are now to be performed in Scandinavia in limited geographic areas before introducing countrywide screening. The Danish State has offered to pay for feasibility studies in two counties. Provided that the results of randomised clinical trials are reproduced according to acceptability and stage of the cancer found and the organisation is feasible, it will then be possible to evaluate newer technologies as well as other methods which have not previously been evaluated in a satisfactory way.


13. DOCID:31505 SCORE: 0.00171427972498326
DOCNO: 15830466
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: chemical synthesis
QUALIFIER: pharmacology
QUALIFIER: chemistry
QUALIFIER: pharmacology
QUALIFIER: chemistry
QUALIFIER: pharmacology
QUALIFIER: chemistry
AUTHOR: M Laronze M
AUTHOR: M Boisbrun M
AUTHOR: S Léonce S
AUTHOR: B Pfeiffer B
AUTHOR: P Renard P
AUTHOR: O Lozach O
AUTHOR: L Meijer L
AUTHOR: A Lansiaux A
AUTHOR: C Bailly C
AUTHOR: J Sapi J
AUTHOR: J-Y Laronze JY
AFFILIATION: CNRS FRE 2715 'Isolement, Structure, Transformations et Synthèse de Produits Naturels', IFR 53, Faculté de Pharmacie, 51 Rue Cognacq Jay, 51096 Reims cedex, France. marie.laronze@univ-reims.fr
PUBTYPE: Journal Article
JOURNALTITLE: Bioorganic & medicinal chemistry.
COUNTRY: England
TITLE: Synthesis and anticancer activity of new pyrrolocarbazoles and pyrrolo-beta-carbolines.
PUBDATE: 20050301
'Bended' 1, 3 or 'linear' 2 pyrrolidino-fused (aza)carbazoles were prepared and screened towards a few cancer-related targets. Whereas 'bended' derivatives 1 and 3 proved to be weakly toxic, several members of the 'linear' family strongly interact with DNA, especially derivative 28a.


14. DOCID:28819 SCORE: 0.00170965940475076
DOCNO: 12070461
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: secondary
QUALIFIER: secondary
AUTHOR: V Gentile V
AUTHOR: G Mariotti G
AUTHOR: F Fattore F
AUTHOR: A Cardi A
AUTHOR: F Di Silverio F
AFFILIATION: Dipartimento di Urologia U. Bracci, Università degli Studi di Roma La Sapienza, Rome, Italy.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Minerva urologica e nefrologica = The Italian journal of urology and nephrology.
COUNTRY: Italy
TITLE: [Penile metastasis from bladder cancer. A case report]
PUBDATE: 20020601
Penile metastases from bladder cancer are unusual. A case of a man, 50 years old, with undifferentiated bladder carcinoma submitted to radical cystoprostatectomy and ileal conduit is presented. Twelve months after the primary diagnosis the patient presented metastases of the penis.