0. DOCID:15411 SCORE: 0.0023908574316747
DOCNO: 2564959
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Mammography
QUALIFIER: radiography
QUALIFIER: radiography
QUALIFIER: radiography
AUTHOR: A P Locker AP
AUTHOR: A R Manhire AR
AUTHOR: V Stickland V
AUTHOR: J Caseldine J
AUTHOR: R W Blamey RW
AFFILIATION: Department of Surgery, City Hospital, Nottingham.
PUBTYPE: Journal Article
JOURNALTITLE: Lancet.
COUNTRY: ENGLAND
TITLE: Mammography in symptomatic breast disease.
PUBDATE: 19890401
The contribution of mammography to the diagnosis of breast cancer was examined in 5080 patients with various breast symptoms. There were 562 breast cancers within this group. The sensitivity of mammography was 88%. Only 18 cancers were detected by mammography alone, and of these 3 were in the other breast. 7 of the remaining 15 cancers had clinical signs which would have been pursued to open biopsy in the absence of mammography. Clinical examination is of paramount importance in the management of patients with symptomatic breast disease. Mammography is most useful when applied in specific situations rather than to screen every patient with breast symptoms.


1. DOCID:14417 SCORE: 0.00232022566473688
DOCNO: 2484296
AUTHOR: R P Moser RP
AUTHOR: M L Johnson ML
AFFILIATION: Dept of Head and Neck Surgery, MD Anderson Cancer Center.
PUBTYPE: Comment
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Oncology (Williston Park, N.Y.)
COUNTRY: UNITED STATES
TITLE: Surgical management of brain metastases: how aggressive should we be?
PUBDATE: 19890601
Treatment of cancer metastatic to the brain is dictated by both the need to achieve immediate short-term palliation and the desire for durable symptom-free remission. Surgical resection of brain metastases makes available tissue for diagnosis and experimental study, permits prompt relief of neurological signs and symptoms secondary to tumor mass effect, enhances the potential for sustained local tumor control in those patients with solitary disease, and allows greater therapeutic flexibility by obviating the need for cranial radiation in some situations and by expanding patient access to alternative experimental protocols or systemic chemotherapy.


2. DOCID:8516 SCORE: 0.00229078775131181
DOCNO: 6386750
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: methods
AUTHOR: J W Martin JW
AUTHOR: R F Jacob RF
AUTHOR: D L Larson DL
AUTHOR: G E King GE
PUBTYPE: Journal Article
JOURNALTITLE: Head & neck surgery.
COUNTRY: UNITED STATES
TITLE: Surgical stents for the head and neck cancer patient.
PUBDATE: 19841001
Split-thickness skin graft reconstruction following intraoral cancer surgery maintains functional mobility within the oral cavity and gives excellent support for the final intraoral rehabilitative prosthesis. We describe the use of a dental material, called tissue conditioner, for skin graft immobilization as an alternative to the usual gauze bolus and thermoplastic materials following surgery in various intraoral anatomic sites.


3. DOCID:10236 SCORE: 0.0022095937887835
DOCNO: 6345937
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Neoplasm Metastasis
QUALIFIER: pathology
AUTHOR: Y T Lee YT
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Journal of surgical oncology.
COUNTRY: UNITED STATES
TITLE: Breast carcinoma: pattern of metastasis at autopsy.
PUBDATE: 19830701
Breast cancer is known to metastasize to all organs of the human body, and its manifestations are protean. It is almost impossible to predict which organ system will be invaded. Since 1950, there are seven autopsy series of patients with breast carcinoma published in the English literature. All data came from American hospitals (total of 2,147 patients), and each report studied more than 100 patients with breast cancer. The reported incidence of involvement of different organ sites are presented in Table I. Although the data came from different institutions and spanned over 35 years (1943-1977), the findings regarding metastatic involvement of specific organs are fairly similar.


4. DOCID:10757 SCORE: 0.00199215653010372
DOCNO: 6620574
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
AUTHOR: H Habu H
AUTHOR: K Takeshita K
AUTHOR: K Hoshi K
AUTHOR: M Menjo M
AUTHOR: N Aoki N
AUTHOR: R Kamiyama R
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [Histopathological evaluation of minute stomach cancer]
PUBDATE: 19830801
We histologically examined 17 lesions from minute gastric cancer (less than 5 mm in diameter). Flat or IIb type was frequently seen in minute cancer (47%); the depressed type was predominant in ordinary early gastric cancer (72%). Differentiated adenocarcinoma was noted more often in minute cancer (88%) than in ordinary early gastric cancer (61%) or advanced cancer (45%). Differentiated type minute cancer was frequently associated with severe atrophic gastritis (93%) and intestinal metaplasia (73%). There was no evidence for the preexistence of chronic peptic ulcer, because no fibrosis was present in the gastric wall beneath the minute cancerous lesions.


5. DOCID:15832 SCORE: 0.00189168067346653
DOCNO: 3469458
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: mortality
AUTHOR: W J Blot WJ
AUTHOR: S S Devesa SS
AUTHOR: J F Fraumeni JF
PUBTYPE: Journal Article
JOURNALTITLE: Journal of the National Cancer Institute.
COUNTRY: UNITED STATES
TITLE: Declining breast cancer mortality among young American women.
PUBDATE: 19870301
Changes in age-specific breast cancer mortality rates among white females in the United States during 1950-80 were shown to be correlated with changes in patterns of childbearing in early adulthood. However, for the most recent 5-year period among women below age 40 years, small declines in breast cancer mortality were observed in the late 1970's, despite a predicted increase following delays in childbearing that began in the 1960's and despite evidence of a rising incidence of the cancer. Although correlation analyses have inherent limitations, the findings raise the possibility that recent changes in the detection and management of breast cancer have contributed to a lowered mortality from this cancer among young American women.


6. DOCID:14570 SCORE: 0.00188934380667115
DOCNO: 3290610
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiography
QUALIFIER: radiography
QUALIFIER: radiography
QUALIFIER: radiography
AUTHOR: E V Krivenko EV
AUTHOR: N V Minkh NV
AUTHOR: V D Chkhikvadze VD
AUTHOR: E G Melent'eva EG
AUTHOR: I A Agrinskaia IA
PUBTYPE: Journal Article
JOURNALTITLE: Meditsinskaia radiologiia.
COUNTRY: USSR
TITLE: [Phlebography of the mediastinum in lung cancer]
PUBDATE: 19880601
The state of the major mediastinal veins was studied in 113 patients with central cancer of the right lung upper lobe with metastases to the regional lymph nodes. Routine angiography was performed in 92 patients, digital subtraction angiography--in 21 patients. Vascularization was shown to be more common in and adenocarcinoma. The authors identified 2 groups of angiographic signs: marked and doubtful ones. They have been of opinion that only the presence of marked signs can be a contraindication for surgical intervention. The informative value of routine angiography was compared with that of digital subtraction angiography.


7. DOCID:9074 SCORE: 0.0018399701607851
DOCNO: 3925717
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analogs & derivatives
QUALIFIER: chemically induced
AUTHOR: S Genedani S
AUTHOR: M Bernardi M
AUTHOR: A Botticelli A
AUTHOR: A Bertolini A
PUBTYPE: Journal Article
JOURNALTITLE: Acta pharmacologica et toxicologica.
COUNTRY: DENMARK
TITLE: Convulsive syndrome induced by the intracerebroventricular injection of alpha-difluoromethylornithine in rats.
PUBDATE: 19850301
In adult rats, the intracerebroventricular injection of alpha-difluoromethylornithine (DFMO), a polyamine antimetabolite which specifically inhibits ornithine-decarboxylase, induces a typical convulsive syndrome (ED50 = 100 micrograms/rat) and death (LD50 = 300 micrograms/rat). Histological lesions are seen only with the highest doses and are essentially restricted to the Ammon's horn neurones. Since DFMO is currently undergoing clinical trials for use in cancer chemotherapy, including brain tumours, its CNS toxicity should be carefully considered.


8. DOCID:11294 SCORE: 0.00182043469769871
DOCNO: 6580978
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: enzymology
QUALIFIER: enzymology
QUALIFIER: enzymology
QUALIFIER: blood
AUTHOR: K Akagi K
AUTHOR: H Tsuji H
AUTHOR: E Kajiwara E
AUTHOR: K Murai K
AUTHOR: T Shikata T
PUBTYPE: Journal Article
JOURNALTITLE: Clinica chimica acta; international journal of clinical chemistry.
COUNTRY: NETHERLANDS
TITLE: Activities of serum acid ribonuclease in patients with malignant neoplasms or with renal failure.
PUBDATE: 19831101
The activities of serum acid ribonuclease (RNase) were determined in patients with malignant neoplasm or with renal failure. The levels were markedly increased in myelogenous leukemia and renal failure, and only slightly increased in solid cancers, lymphoid malignancies and multiple myeloma. These increases correlated significantly with serum LDH activity in myelogenous leukemia and with creatinine levels in other malignancies or renal failure. The acid RNase content of granulocytes was 22.7-fold higher than that of lymphocytes. The increase of serum acid RNase may suggest an increased granulocyte destruction in myelogenous leukemia and a reduced glomerular filtration in other malignant neoplasms and renal failure.


9. DOCID:11760 SCORE: 0.00180198811008506
DOCNO: 6204025
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Drug Implants
DESCRIPTOR: Palliative Care
QUALIFIER: administration & dosage
QUALIFIER: drug therapy
AUTHOR: R D Penn RD
AUTHOR: J A Paice JA
AUTHOR: W Gottschalk W
AUTHOR: A D Ivankovich AD
PUBTYPE: Journal Article
JOURNALTITLE: Journal of neurosurgery.
COUNTRY: UNITED STATES
TITLE: Cancer pain relief using chronic morphine infusion. Early experience with a programmable implanted drug pump.
PUBDATE: 19840801
Fourteen patients were implanted with drug pumps to provide chronic epidural or intrathecal morphine to relieve pain due to cancer. A new programmable pump was used in seven of the patients and a constant infusion device was used in the other seven patients. Results, judged by subjective pain reports (on a 0 to 10 scale), decrease in oral narcotics, and change in activity level, were excellent in eight patients, good in five patients, and poor in one patient. The programmable device has the obvious advantage of being able to vary dose according to patient need and requires less frequent refilling. Four programmable pump failures occurred, two requiring replacement.


10. DOCID:14568 SCORE: 0.00177934710382554
DOCNO: 3403594
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: etiology
AUTHOR: W J Gillespie WJ
AUTHOR: C M Frampton CM
AUTHOR: R J Henderson RJ
AUTHOR: P M Ryan PM
AFFILIATION: Christchurch Hospital, Christchurch School of Medicine, University of Otago, New Zealand.
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of bone and joint surgery. British volume.
COUNTRY: ENGLAND
TITLE: The incidence of cancer following total hip replacement.
PUBDATE: 19880801
We have studied the incidence of tumours at remote sites following total hip replacement: 1,358 individuals have been followed up for 14,286 person-years after operation. In the decade following implantation the incidence of tumours of the lymphatic and haemopoietic systems was significantly greater, and that of cancer of the breast, colon, and rectum, significantly less than expected. Whilst the association might be due in part to an effect of the prosthetic implants, other mechanisms, particularly drug therapy, require consideration.


11. DOCID:14234 SCORE: 0.0017200119234931
DOCNO: 3625847
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Prostatectomy
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: methods
AUTHOR: P K Reddy PK
AUTHOR: P H Lange PH
AUTHOR: E E Fraley EE
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of urology.
COUNTRY: UNITED STATES
TITLE: Bladder replacement after cystoprostatectomy: efforts to achieve total continence.
PUBDATE: 19870901
Total bladder replacement with tubular sigmoid colon and detubularized ileocecal bowel segments was performed on 17 patients after cystoprostatectomy for bladder cancer. There were few complications and patient acceptance was excellent. Daytime continence was achieved in most patients but voiding patterns were superior with detubularized segments. However, enuresis was common with both segment types. Total urinary continence (day and nighttime continence) was achieved in 7 patients with an artificial urinary sphincter that was activated only at night. Total bladder replacement is an acceptable form of urinary diversion after cystoprostatectomy in appropriate patients.


12. DOCID:15685 SCORE: 0.00169467171560382
DOCNO: 2805561
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: M S Halata MS
AUTHOR: J Miller J
AUTHOR: R K Stone RK
AFFILIATION: Department of Pediatrics, New York Medical College, Metropolitan Hospital Center, New York, New York 10029.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Clinical pediatrics.
COUNTRY: UNITED STATES
TITLE: Gardner syndrome. Early presentation with a desmoid tumor. Discovery of multiple colonic polyps.
PUBDATE: 19891101
A 14-year-old patient who was eventually found to have Gardner syndrome initially presented at the age of 3 years with a desmoid tumor involving the scalp. A careful review of the family history revealed a high incidence of colonic cancer, which prompted endoscopic evaluation of the patient. The discovery of adenomatous polyps in the colon confirmed the diagnosis of Gardner syndrome. In patients with hard or soft tissue tumors, the possibility of Gardner syndrome should be kept in mind, and a thorough family history taken. Early diagnosis may prevent malignant transformation of colonic polyps.


13. DOCID:15517 SCORE: 0.00165791888594915
DOCNO: 3366487
AUTHOR: F de Waard F
AUTHOR: D Trichopoulos D
AFFILIATION: National Institute of Public Health and Environmental Protection, Bilthoven, The Netherlands.
PUBTYPE: Journal Article
JOURNALTITLE: International journal of cancer. Journal international du cancer.
COUNTRY: UNITED STATES
TITLE: A unifying concept of the aetiology of breast cancer.
PUBDATE: 19880501
A number of risk factors for breast cancer are considered jointly in one pathogenetic framework which relates to the formation of pre-cancerous lesions. Energy-rich diet during puberty and adolescence enhances the occurrence of pre-cancerous lesions in the breast. This process is counteracted by full-term pregnancies, and the earlier they come the fewer the number of such lesions. Energy-rich diet later in life contributes to the occurrence of obesity which, after menopause, enhances the growth of existing subclinical and clinical breast cancer. In both periods of life the nutritional factor exerts its effect through endocrine mechanisms in which oestrogens play a major part.


14. DOCID:15171 SCORE: 0.00163286818320561
DOCNO: 2800494
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: I I Degtiareva II
AUTHOR: A V Gań≠senko AV
AUTHOR: N M Putseva NM
PUBTYPE: Journal Article
JOURNALTITLE: Vrachebnoe delo.
COUNTRY: USSR
TITLE: [Laboratory diagnosis of pancreatitis and pancreatic cancer]
PUBDATE: 19890701
The content of fibrin fibrinogen splitting products (FSP), radioimmune trypsin, C-peptide and carbohydrate antigen (CA) 19-9 in the blood of 82 patients with acute pancreatitis (edematous and hemorrhagic), and chronic recurrent pancreatitis at the stage of exacerbation, 42 patients with chronic pancreatitis, 34 patients with cancer of the pancreas (stages III-IV) and 22 healthy persons were studied. Results indicate a high diagnostic value of determination FSP, trypsin and C-peptide in patients with acute pancreatitis and chronic recurring pancreatitis at the stage of exacerbation, trypsin and C-peptide in patients with chronic pancreatitis associated with severe exocrine insufficiency of the pancreas, KA 19-9 in patients with cancer of the pancreas.