0. DOCID:18236 SCORE: 0.00499693132721413
DOCNO: 8318406
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Lectins
QUALIFIER: pathology
PUBTYPE: Journal Article
PUBTYPE: Multicenter Study
JOURNALTITLE: British journal of cancer.
COUNTRY: ENGLAND
TITLE: Prognostic value of Helix pomatia in breast cancer. International (Ludwig) Breast Cancer Study Group.
PUBDATE: 19930701
Six hundred and eighty-four primary breast cancers from the International (Ludwig) Breast Cancer Study Group (IBCSG) were studied for Helix pomatia lectin (HPA) binding. There was a weak correlation between lymph node-positive and HPA positive (P = 0.04). In our series there was a large advantage in disease-free survival (DFS) and overall survival (OS) for node-negative patients (P < 0.0001 DFS and OS). However, there was no such advantage for HPA-negative patients (P = 0.23 DFS and P = 0.32 OS). We conclude that in this randomised patient group HPA is of no clinical predictive value.

1. DOCID:3989 SCORE: 0.00310001103756939
DOCNO: 61154
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analysis
QUALIFIER: blood
QUALIFIER: analysis
AUTHOR: R Lamerz R
AUTHOR: U Schmalhorst U
AUTHOR: J Grunst J
AUTHOR: A Fateh-Moghadam A
AUTHOR: J Eisenburg J
PUBTYPE: Journal Article
JOURNALTITLE: Fortschritte der Medizin.
COUNTRY: GERMANY, WEST
TITLE: [Significance of serum alpha-fetoprotein determination. Experiences with our own radioimmunoassay]
PUBDATE: 19760401
Alpha-fetoprotein (AFP) was determined by a new radioimmunoassay in the sera of patients with different liver diseases. Compared to a normal group (n = 140, AFP levels below 15 ng/ml), most elevated AFP concentrations were found in 18 patients with primary liver cancer (PLC), 7 of whom showed Ouchterlony-positive levels (above 10,000 ng/ml). In 3 cases with liver cirrhosis, PLC was first suggested by high AFP levels between 1000 and 3600 ng/ml and later confirmed by histology. On the other hand, only 6 from 15 patients with other primary tumors and liver metastasis had AFP concentrations between 20 and 111 ng/ml. In 90% of 102 patients with liver cirrhosis AFP levels below 20 ng/ml were determined, while 13 cases showed elevated values up to 134 ng/ml. A transitory AFP increase between 20 and 238 ng/ml was seen in 32% of 63 cases in the early stage of acute hepatitis but 65% of 31 these cases in follow-up studies. 3 of 7 cases of chronic hepatitis gave similar results. The maximal AFP levels developed following the maximal transaminase activities by 5-18 days and coincided with a decrease of cholinesterase activity. The radioimmunological determination of AFP is recommended for earlier detection of the development of PLC in liver cirrhosis patients.

2. DOCID:29337 SCORE: 0.0030955967561268
DOCNO: 16474761
OWNER: NLM
STATUS: In-Data-Review
AUTHOR: Michael W Kattan MW
AFFILIATION: MW Kattan is Chairman of the Department of Quantitative Health Sciences at the Cleveland Clinic Foundation, OH, USA.
PUBTYPE: Journal Article
JOURNALTITLE: Nature clinical practice. Urology.
COUNTRY: United States
TITLE: When and how to use informatics tools in caring for urologic patients.
PUBDATE: 20050401
Making predictions is an essential part of any medical decision. It is particularly crucial when considering treatment of clinically localized prostate cancer. Nomograms and prediction model software typically provide the most accurate predictions. Many nomograms have been developed, for all prostate cancer clinical states. Some of these are discussed in this review, as is their utility in facilitating decision making and informed consent.

3. DOCID:28879 SCORE: 0.00309557839384329
DOCNO: 16354327
OWNER: NLM
STATUS: In-Process
AUTHOR: Luciano Wannesson L
AUTHOR: Franco Cavalli F
AUTHOR: Emmanuele Zucca E
AFFILIATION: Department of Medical Oncology, Institute of Southern Switzerland, Bellinzona, Switzerland.
PUBTYPE: Journal Article
JOURNALTITLE: Clinical lymphoma & myeloma.
COUNTRY: United States
TITLE: Primary pulmonary lymphoma: current status.
PUBDATE: 20051101
Primary pulmonary lymphoma (PPL) is a rare disease with a favorable prognosis compared with lung cancer. Although a number of histologic variables of B- and T-cell lymphoma were reported as PPL, marginal zone lymphoma of the mucosa-associated lymphoid tissue type is by far the most frequent diagnosis. This review summarizes the present knowledge of histopathology, molecular biology, diagnosis, prognosis, and treatment of this heterogeneous entity.

4. DOCID:5966 SCORE: 0.00264491360970359
DOCNO: 6158356
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: A Mannell A
PUBTYPE: Journal Article
JOURNALTITLE: The British journal of surgery.
COUNTRY: ENGLAND
TITLE: Presternal gastric bypass for unresectable carcinoma of the thoracic oesophagus: a preliminary report.
PUBDATE: 19800701
Presternal gastric bypass was performed on 10 African patients with unresectable carcinoma of the thoracic oesophagus. Where the cancer involved the lower third of the thoracic oesophagus the oesophagus was simply excluded. However, for cancer of the upper and middle third of the thoracic oesophagus the additional step of Roux-en-Y jejunal anastomosis to the intra-abdominal oesophagus was performed to drain away oesophageal secretions from existing or imminent tracheo-oesophageal fistulas. No patient died as a result of the operation, and 9 out of 10 patients were able to eat normally afterwards. Presternal gastric bypass is compared with other methods of palliation for unresectable carcinoma of the thoracic oesophagus.

5. DOCID:19231 SCORE: 0.00260220778035004
DOCNO: 1737398
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: metabolism
QUALIFIER: metabolism
AUTHOR: X L Han XL
AUTHOR: J G Liehr JG
AFFILIATION: Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston 77550-2782.
PUBTYPE: Journal Article
JOURNALTITLE: Cancer research.
COUNTRY: UNITED STATES
TITLE: Induction of covalent DNA adducts in rodents by tamoxifen.
PUBDATE: 19920301
The antiestrogen tamoxifen, increasingly used as adjuvant treatment for breast cancer, has been found to covalently modify DNA of rodents. For instance, the liver DNA of female Sprague-Dawley rats treated with a single injection of tamoxifen contained two DNA adducts. Four additional DNA adducts were formed and adduct concentrations increased 5- 7- and 10-15-fold after three and six tamoxifen injections, respectively, from levels observed after a single dose. The accumulation of DNA adducts with repeated administrations of tamoxifen to rodents may make this drug a poor choice for the chronic preventative treatment of breast cancer.

6. DOCID:27930 SCORE: 0.00250931975675797
DOCNO: 10683075
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: diagnosis
QUALIFIER: etiology
QUALIFIER: diagnosis
AUTHOR: B D Keith BD
AUTHOR: V H Bramwell VH
AFFILIATION: London Regional Cancer Center, Ontario, Canada.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: American journal of clinical oncology : the official publication of the American Radium Society.
COUNTRY: UNITED STATES
TITLE: Pyomyositis after chemotherapy for breast cancer.
PUBDATE: 20000201
Pyomyositis is a rare complication of chemotherapy. A 47-year-old woman with metastatic breast cancer, in whom pyomyositis developed after chemotherapy, is described. It was difficult to differentiate between pyomyositis and deep venous thrombosis early in her admission. Pyomyositis should be considered part of the differential diagnosis of deep venous thrombosis. This infection, after chemotherapy, usually is considered to be caused by neutropenia or immunodeficiency secondary to the cancer, or both. It is postulated that subclinical myopathy, secondary to the malignancy or drugs used in treating the malignancy, or both, may also predispose to pyomyositis.

7. DOCID:3726 SCORE: 0.00246282730184909
DOCNO: 136108
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: mortality
AUTHOR: R Schmauz R
AUTHOR: M Holm-Hadulla M
PUBTYPE: Historical Article
PUBTYPE: Journal Article
JOURNALTITLE: Zeitschrift für Krebsforschung und klinische Onkologie. Cancer research and clinical oncology.
COUNTRY: GERMANY, WEST
TITLE: Cancer mortality in Württemberg, 1910 and 1970.
PUBDATE: 19760901
The results of a special survey of cancer mortality statistics in selected areas of the Ober- and Unterland of Württemberg in the period 1908--1912 were compared with the official mortality statistics of the same region for 1969--1972. In the Oberland, formerly part of an area of high cancer mortality comprising the adjacent regions of Bavaria, Austria, Switzerland, and Baden, the overall cancer mortality showed a marked fall in both sexes. In the Unterland, where cancer mortality was previously low, the overall death rate increased in men and did not change in women. These variations are largely accounted for by changes in mortality from cancer of the stomach and bronchus. The death rates from gastric cancer observed around 1900 in the Oberland of Württemberg and adjacent regions of the neighbouring countries are among the highest recorded even in the world. Since the fall of gastric cancer noted is very marked and this disease is still the leading cause of death from cancer today, the Oberland of Württemberg seems to be uniquely suited for the search of environmental factors which associate with this decline. In theremainder of cancer sites changes over time were less striking and/or observed already in other countries.

8. DOCID:26031 SCORE: 0.00243883814228418
DOCNO: 11484991
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
QUALIFIER: therapeutic use
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
QUALIFIER: therapeutic use
AUTHOR: Y Michiwa Y
AUTHOR: M Earashi M
AUTHOR: H Kobayashi H
AUTHOR: N Matsuki N
AFFILIATION: Dept. of Surgery, Toyama Rosai Hospital, Uozu, Japan. surgery@keiju.co.jp
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Journal of experimental & clinical cancer research : CR.
COUNTRY: Italy
TITLE: Cutaneous metastases from gastric adenocarcinoma treated with combination chemotherapy producing complete response with long survival.
PUBDATE: 20010601
A case of cutaneous metastases from gastric adenocarcinoma was presented. It was treated with combination chemotherapy producing complete response with prolongation of survival. Skin metastasis will indicate early fatal termination, therefore there has not yet been a reported case of cutaneous metastasis from gastric cancer to have complete response with long survival.

9. DOCID:23051 SCORE: 0.0023982085524768
DOCNO: 9067076
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Mammography
DESCRIPTOR: Mass Screening
DESCRIPTOR: Physical Examination
QUALIFIER: prevention & control
AUTHOR: M E Costanza ME
AUTHOR: K L Edmiston KL
AFFILIATION: University of Massachusetts Medical Center, Department of Medicine, Worcester 01655, USA.
PUBTYPE: Journal Article
JOURNALTITLE: Comprehensive therapy.
COUNTRY: UNITED STATES
TITLE: Breast cancer screening: early recognition.
PUBDATE: 19970101
The epidemic of breast cancer and the availability of tools to increase early detection and decrease mortality require care and diligence on the part of every physician directly caring for patients. With the widespread implementation of managed care, primary care physicians are in the best position to recommend breast cancer screening. Educational programs to emphasize the primary care physician's role in breast cancer prevention and detection, to improve physical examination skills, and to implement office systems to facilitate screening should be available to primary care physicians, and may have a major impact on breast cancer mortality in the future.

10. DOCID:15411 SCORE: 0.0023908574316747
DOCNO: 2564959
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Mammography
QUALIFIER: radiography
QUALIFIER: radiography
QUALIFIER: radiography
AUTHOR: A P Locker AP
AUTHOR: A R Manhire AR
AUTHOR: V Stickland V
AUTHOR: J Caseldine J
AUTHOR: R W Blamey RW
AFFILIATION: Department of Surgery, City Hospital, Nottingham.
PUBTYPE: Journal Article
JOURNALTITLE: Lancet.
COUNTRY: ENGLAND
TITLE: Mammography in symptomatic breast disease.
PUBDATE: 19890401
The contribution of mammography to the diagnosis of breast cancer was examined in 5080 patients with various breast symptoms. There were 562 breast cancers within this group. The sensitivity of mammography was 88%. Only 18 cancers were detected by mammography alone, and of these 3 were in the other breast. 7 of the remaining 15 cancers had clinical signs which would have been pursued to open biopsy in the absence of mammography. Clinical examination is of paramount importance in the management of patients with symptomatic breast disease. Mammography is most useful when applied in specific situations rather than to screen every patient with breast symptoms.

11. DOCID:1910 SCORE: 0.00235826826716906
DOCNO: 898018
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Thoracoscopy
AUTHOR: L R Radigan LR
AUTHOR: J L Glover JL
PUBTYPE: Journal Article
JOURNALTITLE: Surgery.
COUNTRY: UNITED STATES
TITLE: Thoracoscopy.
PUBDATE: 19771001
Poor results in the treatment of lung cancer have led to the development of several techniques designed to obtain tissue for diagnosis and to determine the feasibility of resection. Although mediastinoscopy has obtained great popularity, we have been dissatisfied with it because of the low yield of positive results and the attendant increases in length of operations and hospitalizations. We have modified the old technique of thoracoscopy, using a sterilized sigmoidoscope inserted through an intercostal space with the patient positioned and prepared for thoracotomy. Although most frequently used in patients with lung cancer, this procedure also has been helpful in patients with coin lesions, mediastinal tumors, and penetrating wounds of the chest. Although we agree that mediastinoscopy is useful in selected patients, we believe that thoracoscopy offers a greater number of patients a reliable means of obtaining the proper diagnosis more efficiently.

12. DOCID:19164 SCORE: 0.00235549651034465
DOCNO: 2202380
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: immunology
QUALIFIER: immunology
AUTHOR: I F McKenzie IF
AUTHOR: P X Xing PX
AFFILIATION: Department of Pathology, University of Melbourne, Parkville, Victoria, Australia.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Cancer cells (Cold Spring Harbor, N.Y. : 1989)
COUNTRY: UNITED STATES
TITLE: Mucins in breast cancer: recent immunological advances.
PUBDATE: 19900301
Mucins are heavily glycosylated proteins that are produced in excessive amounts in breast cancers and other adenocarcinomas. These proteins are potent immunogens; indeed, most monoclonal antibodies raised against extracts of breast cancer cells or tumors are directed toward a single family of mucins. The anti-mucin antibodies currently available are valuable diagnostic aids for detecting advanced stages of breast cancer. To improve the sensitivity of these antibodies so that they might be suitable for use in screening and early diagnosis, tumor imaging, and therapy of breast cancer, recent studies have focused on identifying the precise epitopes they recognize.

13. DOCID:22305 SCORE: 0.00233394995452921
DOCNO: 7552793
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Parenteral Nutrition, Total
QUALIFIER: therapy
AUTHOR: A D Hill AD
AUTHOR: J M Daly JM
AFFILIATION: Department of Surgery, New York Hospital/Cornell University Medical Center, New York, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Surgical oncology clinics of North America.
COUNTRY: UNITED STATES
TITLE: Current indications for intravenous nutritional support in oncology patients.
PUBDATE: 19950701
No clear role has yet been defined for the role of total parenteral nutrition in the management of the cancer patient, and this subject remains an area of controversy. Peri-operative nutritional support, if given for at least 10 days, may reduce morbidity and mortality in some patients, although this subgroup has not been fully characterized. There is no evidence that parenteral nutritional support benefits patients undergoing chemotherapy or radiotherapy in terms of an increased tumor response rate or prolongation of survival.

14. DOCID:14417 SCORE: 0.00232022566473688
DOCNO: 2484296
AUTHOR: R P Moser RP
AUTHOR: M L Johnson ML
AFFILIATION: Dept of Head and Neck Surgery, MD Anderson Cancer Center.
PUBTYPE: Comment
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Oncology (Williston Park, N.Y.)
COUNTRY: UNITED STATES
TITLE: Surgical management of brain metastases: how aggressive should we be?
PUBDATE: 19890601
Treatment of cancer metastatic to the brain is dictated by both the need to achieve immediate short-term palliation and the desire for durable symptom-free remission. Surgical resection of brain metastases makes available tissue for diagnosis and experimental study, permits prompt relief of neurological signs and symptoms secondary to tumor mass effect, enhances the potential for sustained local tumor control in those patients with solitary disease, and allows greater therapeutic flexibility by obviating the need for cranial radiation in some situations and by expanding patient access to alternative experimental protocols or systemic chemotherapy.