0. DOCID:15434 SCORE: 0.000250014321887307
DOCNO: 2824111
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analysis
QUALIFIER: immunology
AUTHOR: J L Vila JL
AUTHOR: C Juarez C
AUTHOR: I Illa I
AUTHOR: M Agusti M
AUTHOR: C Gelpi C
AUTHOR: M J Amengual MJ
AUTHOR: J L Rodriguez JL
AFFILIATION: Department of Immunology, Hospital de Sant Pau, Universitat Autonoma de Barcelona, Spain.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Clinical immunology and immunopathology.
COUNTRY: UNITED STATES
TITLE: Autoantibodies against the H1(0) subtype of histone H1.
PUBDATE: 19871201
The specificity of antinuclear autoantibodies in a patient with a sensory neuropathy associated with cancer has been analyzed. The autoantibodies recognize the histone H1(0) as shown by its dissociation from DNA, perchloric solubility, electrophoretic mobility in SDS or urea/acid polyacrylamide gels, and by the capacity of purified H1(0) to block the reactivity of these autoantibodies. Almost no reactivity was observed with other subtypes of H1. To our knowledge, this is the first autoantibody described with such specific reactivity for the H1(0) subtype.


1. DOCID:12987 SCORE: 0.000250013702361754
DOCNO: 3818819
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Antineoplastic Agents
DESCRIPTOR: Drug Evaluation, Preclinical
DESCRIPTOR: Drug Information Services
AUTHOR: M T Zehnacker MT
AUTHOR: R H Brennan RH
AUTHOR: G W Milne GW
AUTHOR: J A Miller JA
PUBTYPE: Journal Article
JOURNALTITLE: Journal of chemical information and computer sciences.
COUNTRY: UNITED STATES
TITLE: The NCI Drug Information System. 5. DIS Biology Module.
PUBDATE: 19861101
The NCI drug screening program tests over 10,000 chemicals per year for activity against cancer. The associated Drug Information System (DIS) captures all the raw testing data and provides for its validation. The large quantity of numeric data gathered during testing is maintained within the DIS in a database that is interactively searchable and automatically updated at regular intervals.


2. DOCID:12765 SCORE: 0.000250012291780973
DOCNO: 2769539
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: N S Adzick NS
AUTHOR: J H Fisher JH
AUTHOR: H S Winter HS
AUTHOR: R H Sandler RH
AUTHOR: W H Hendren WH
AFFILIATION: Department of Surgery, Children's Hospital, Boston, MA 02115.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Journal of pediatric surgery.
COUNTRY: UNITED STATES
TITLE: Esophageal adenocarcinoma 20 years after esophageal atresia repair.
PUBDATE: 19890801
We report a case of esophageal adenocarcinoma 20 years after esophageal atresia repair. From one case report it is premature to recommend cancer surveillance for all esophageal atresia patients. However, the first survivors are now reaching an age when esophageal cancer related to chronic esophagitis may become more prevalent.


3. DOCID:12274 SCORE: 0.000250009852397153
DOCNO: 2671728
AUTHOR: K Wrenn K
AFFILIATION: Department of Medicine, University of Rochester, NY.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The New England journal of medicine.
COUNTRY: UNITED STATES
TITLE: Fecal impaction.
PUBDATE: 19890901
Fecal impaction is a common disorder with variable presentation and many potential complications. Its pathophysiology is complex, and the treatment is often difficult and frustrating. Preventive measures are likely to be cost effective in populations at high risk, such as institutionalized or debilitated elderly people, mentally ill patients, those with chronic renal failure or cancer, and those who are neurologically impaired.


4. DOCID:15722 SCORE: 0.00025000944815087
DOCNO: 3674061
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: E J Seifter EJ
AUTHOR: M L Levitt ML
AUTHOR: B S Kramer BS
AFFILIATION: National Cancer Institute-Navy Medical Oncology Branch, Uniformed Services University for the Health Sciences, Bethesda, Maryland.
PUBTYPE: Journal Article
JOURNALTITLE: The American journal of medicine.
COUNTRY: UNITED STATES
TITLE: An outlier theory of cancer curability. Tumor cell differentiation as a therapeutic goal.
PUBDATE: 19871001
Combinations of cytotoxic agents that cure a substantial percentage of patients with several childhood and adult malignancies are much less efficacious for the majority of solid tumors. Standard approaches for curability that rely solely on the concept of cytotoxicity may not be applicable for most epithelial and mesenchymal solid malignancies. Differentiation may play a more important role in cancer cure than heretofore suspected. Clinical and experimental evidence supports further investigation into models of inducing tumor cell differentiation. The question of why such models could predict for curative modalities of treatment is discussed.


5. DOCID:12141 SCORE: 0.000250008665220568
DOCNO: 3829017
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: adverse effects
QUALIFIER: adverse effects
QUALIFIER: etiology
AUTHOR: V F Holmes VF
AUTHOR: F Adams F
AUTHOR: F Fernandez F
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Cancer treatment reports.
COUNTRY: UNITED STATES
TITLE: Respiratory dyskinesia due to antiemetic therapy in a cancer patient.
PUBDATE: 19870401
Cancer patients commonly receive neuroleptics as antiemetics to relieve nausea and vomiting induced by chemotherapeutic agents. Respiratory dyskinesia, an infrequent, acute, neuroleptic-induced, dystonic reaction, is a potentially life-threatening entity that responds promptly to anticholinergic medication.


6. DOCID:12721 SCORE: 0.000250008401504243
DOCNO: 2560771
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: drug therapy
QUALIFIER: drug therapy
AUTHOR: F Kearns F
AUTHOR: L Grogan L
AUTHOR: P Harford P
AUTHOR: D N Carney DN
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Irish journal of medical science.
COUNTRY: IRELAND
TITLE: Resolution of small cell lung cancer intracranial metastases with standard dose chemotherapy.
PUBDATE: 19891201
Brain metastases are a well recognized problem in patients with small cell lung cancer (SCLC). Most patients are treated with whole brain cranial irradiation therapy which frequently improves symptoms. In this report we present data on two patients who achieved radiologically confirmed complete resolution of brain metastases treated with standard dose chemotherapy for SCLC.


7. DOCID:13663 SCORE: 0.000250007837603178
DOCNO: 2575058
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: B A Snowman BA
AUTHOR: V K Malviya VK
AUTHOR: W Brown W
AUTHOR: J M Malone JM
AUTHOR: G Deppe G
AFFILIATION: Wayne State University School of Medicine, Division of Gynecologic Oncology, Hutzel Hospital, Detroit, MI 48201.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.
COUNTRY: IRELAND
TITLE: Actinomycosis mimicking pelvic malignancy.
PUBDATE: 19891101
Pelvic actinomyces, usually a complication of an intrauterine device (IUD), is uncommon and may present a diagnostic dilemma because of an atypical clinical presentation. We present a patient with a cervical tumor, extensive parametrial induration with involvement of the posterior bladder wall, and regional lymph nodes which mimicked advanced cervical cancer and presented a significant diagnostic problem.


8. DOCID:15326 SCORE: 0.000250007779634961
DOCNO: 2550199
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: methods
QUALIFIER: surgery
AUTHOR: Y H Lao YH
AFFILIATION: Henan Tumor Hospital, Zhengzhou.
PUBTYPE: Journal Article
JOURNALTITLE: Zhonghua zhong liu za zhi [Chinese journal of oncology].
COUNTRY: CHINA
TITLE: [Radical total gastrectomy and improved operation in gastric cancer]
PUBDATE: 19890101
1089 patients with gastric cancer resected from 1979-1986 are analysed. Of 1089 patients, 105 underwent total gastrectomy, including 55 by routine method as control and 50 by improved method as study group. The improved total gastrectomy was to take the jejunum instead of a gastric pouch for reconstruction of alimentary tract. End-to-side anastomosis was carried out by stapling devise, forming a reversed "7" gastric substitute and ensuring blood supply as well as physiologic patency and less postoperative complications. This technique is simple and easy to be adopted. The incidence of complication was 9% without operative mortality in this series. The 5-year survival rate was 35.75%.


9. DOCID:13310 SCORE: 0.000250007514168652
DOCNO: 3383119
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: drug therapy
AUTHOR: C J Wynne CJ
AUTHOR: J H Kearsley JH
AFFILIATION: Queensland Radium Institute, Herston, Australia.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Merkel cell tumor. A chemosensitive skin cancer.
PUBDATE: 19880701
The clinical courses of six patients treated with cytotoxic chemotherapy for recurrent Merkel cell tumor of the skin are reported. All patients experienced prompt clinical responses to chemotherapy (five complete response [CR], one partial response [PR]) and three patients (50%) have achieved long-term disease-free remission. The report highlights (1) the aggressive nature of Merkel cell skin cancer, (2) the highly chemosensitive nature of the disease, and (3) some practical problems in administering chemotherapy to elderly patients.


10. DOCID:14355 SCORE: 0.000250007238889933
DOCNO: 2920356
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: L C Wong LC
AUTHOR: D T Choy DT
AUTHOR: H Y Ngan HY
AUTHOR: J S Sham JS
AUTHOR: H K Ma HK
AFFILIATION: Department of Obstetrics and Gynaecology, University of Hong Kong.
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: 4-epidoxorubicin in recurrent cervical cancer.
PUBDATE: 19890401
Thirty-eight patients with histologically proven recurrent cervical cancer were treated with epirubicin, an analogue of anthracycline. There were eight complete responders and ten partial responders. The overall response rate was 47.8%. The survival duration of the responders was significantly longer than that of the nonresponders. The optimal dose of epirubicin has yet to be determined. The dosage of 120 mg/m2 was well tolerated. The role of epirubicin as an adjuvant chemotherapeutic agent in the treatment of cervical cancer was discussed.


11. DOCID:12039 SCORE: 0.000250006798112736
DOCNO: 3522851
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: therapy
AUTHOR: G Greenstein G
AUTHOR: C Berman C
AUTHOR: R Jaffin R
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Journal of periodontology.
COUNTRY: UNITED STATES
TITLE: Chlorhexidine. An adjunct to periodontal therapy.
PUBDATE: 19860601
Chlorhexidine is an effective antimicrobial agent. Its application can enhance periodontal therapy. The pharmacology of chlorhexidine and suggestions for its use are outlined. In addition, its potential for inducing cancer and bacterial resistance are discussed.


12. DOCID:14179 SCORE: 0.000250006605489507
DOCNO: 3794534
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
AUTHOR: C J Randall CJ
AUTHOR: H J Shaw HJ
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of laryngology and otology.
COUNTRY: ENGLAND
TITLE: Malignant tumours of the tongue in young adults. Experience of a secondary referral centre.
PUBDATE: 19861101
Twenty-three cases of malignant tongue tumours in patients aged 15 to 30 are reported. Treatment and prognosis in the 18 for which follow-up information is available are discussed. The disease appears to be very similar to that in older subjects except for a greater incidence of neck node metastases. Close follow-up after primary treatment is essential since there is a high possibility of recurrent disease but which may respond well to salvage surgery if identified early. A greater awareness of the occurrence of tongue cancer in young adults is also necessary.


13. DOCID:14930 SCORE: 0.000250006254805231
DOCNO: 2837828
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
AUTHOR: A F Gazdar AF
AUTHOR: R I Linnoila RI
AFFILIATION: NCI-Navy Medical Oncology Branch, Bethesda, MD 20814.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Seminars in oncology.
COUNTRY: UNITED STATES
TITLE: The pathology of lung cancer--changing concepts and newer diagnostic techniques.
PUBDATE: 19880601
While the basic classification of lung cancer has not altered drastically over the course of the last several years, histologic criteria have undergone a slow, progressive evolution. Input from biological studies has aided the subtyping of some tumors, especially SCLC, and helped delineate the importance of the accurate typing of NSCLC. Newer technological advances, especially in molecular biology, and application of established immunohistochemical techniques using newly generated antibodies are beginning to impact on diagnosis and typing. The evolution and application of clinical protocols directed to specific types or subtypes of lung cancer will provide an even greater impetus to these studies.


14. DOCID:13044 SCORE: 0.0002500060733069
DOCNO: 3943763
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: radiotherapy
QUALIFIER: etiology
QUALIFIER: etiology
AUTHOR: T Matsuyama T
AUTHOR: N Tsukamoto N
AUTHOR: K Matsukuma K
AUTHOR: T Kamura T
AUTHOR: K Jingu K
PUBTYPE: Journal Article
JOURNALTITLE: Gynecologic oncology.
COUNTRY: UNITED STATES
TITLE: Uterine perforation at the time of brachytherapy for the carcinoma of the uterine cervix.
PUBDATE: 19860201
Sixty-one patients with cancer of the uterine cervix received pretreatment laparotomy before the radiotherapy. As an operative procedure, several hemostatic clips were put on the serosal surface of the uterine wall in order to visualize the uterine contour in the localization X-ray films. By this method, six patients among them were proved to have uterine perforation at the time of small source insertion.