0. DOCID:4629 SCORE: 0.000250014135604226
DOCNO: 6269721
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: etiology
QUALIFIER: complications
AUTHOR: M L Hayward ML
AUTHOR: D A Howell DA
AUTHOR: J F O'Donnell JF
AUTHOR: L H Maurer LH
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Hypercalcemia complicating small-cell carcinoma.
PUBDATE: 19811001
Hypercalcemia is a common paraneoplastic syndrome complicating some varieties of lung cancer. It has rarely been reported with small-cell carcinoma of the lung. Seven cases of hypercalcemia complicating small-cell carcinoma of the lung are described; clinical features indicate that significant bone or bone marrow involvement is present in all cases. Parathormone assays were found to be generally in the normal range, though inappropriate for the levels of hypercalcemia.


1. DOCID:5830 SCORE: 0.000250014099792117
DOCNO: 7272931
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: administration & dosage
AUTHOR: A Manni A
AUTHOR: B M Arafah BM
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Tamoxifen-induced remission in breast cancer by escalating the dose to 40 mg daily after progression on 20 mg daily: a case report and review of the literature.
PUBDATE: 19810801
An 80-year-old woman with metastatic breast cancer to the lungs and bones was treated with tamoxifen, 10 mg twice daily, with arrest of disease of six month's duration. At the time of progression, increasing the dosage to 20 mg twice daily resulted in an objective remission now lasting 8+ months. This finding indicates that in this patient, the tamoxifen dosage of 40 mg/daily had a significantly higher anti-tumor effect than 20 mg/daily. Pertinent literature on the correlation of response with tamoxifen dosage is reviewed.


2. DOCID:6614 SCORE: 0.000250011867691465
DOCNO: 361145
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Hyperbaric Oxygenation
QUALIFIER: radiotherapy
AUTHOR: S Dische S
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
JOURNALTITLE: The British journal of radiology.
COUNTRY: ENGLAND
TITLE: Hyperbaric oxygen: the Medical Research Council trials and their clinical significance.
PUBDATE: 19781101
The clinical trials of the use of hyperbaric oxygen in radiotherapy conducted by the Medical Research Council's working party have shown that local cure and survival can be improved in head and neck and cervical cancer. Evidence for benefit has been presented in carcinoma of bronchus, but none has so far been found in carcinoma of the bladder. Although hyperbaric oxygen has produced increased effect upon normal tissues as well as upon tumour, a real improvement in therapeutic ratio appears to be present. The future use of hyperbaric oxygen in radiotherapy will depend upon a comparison of effectiveness with other methods now being tested to improve radiotherapy. The trials have yielded much fundamental and clinical data of general relevance in the radiotherapy of malignant disease.


3. DOCID:4411 SCORE: 0.000250011575194656
DOCNO: 6272398
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analysis
QUALIFIER: analysis
QUALIFIER: analysis
QUALIFIER: analysis
AUTHOR: T W Moody TW
AUTHOR: C B Pert CB
AUTHOR: A F Gazdar AF
AUTHOR: D N Carney DN
AUTHOR: J D Minna JD
PUBTYPE: Journal Article
JOURNALTITLE: Science.
COUNTRY: UNITED STATES
TITLE: High levels of intracellular bombesin characterize human small-cell lung carcinoma.
PUBDATE: 19811201
"Small cells" or "oat cells" characterize a virulent form of lung cancer and share many biochemical properties with peptide-secreting neurones. The neuropeptide bombesin is present in all small-cell lines examined, but not in other lung cancer cell lines, suggesting that bombesinergic precursor cells in lung may give rise to this disease.


4. DOCID:6363 SCORE: 0.00025001119804252
DOCNO: 6449133
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: H Sonobe H
AUTHOR: Y Sato Y
AUTHOR: Y Suzuki Y
AUTHOR: K Hayashi K
AUTHOR: K Kawabata K
AUTHOR: K Ogawa K
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Acta medica Okayama.
COUNTRY: JAPAN
TITLE: Bilateral fat necrosis of the breast: report of a case.
PUBDATE: 19801101
A rare case of bilateral fat necrosis of the breast is reported. The patient was a 50-year-old unmarried woman having no history of trauma, disease or surgery of the breast. In the bilateral breasts, ill-defined, firm masses with skin retraction were noted. Bilateral breast cancer was diagnosed clinically. However, both lesions showed histologically chronic granulomatous inflammation with foci of fatty necrosis, infiltration of lymphocytes, plasma cells, lipid containing foamy cells, foreign body giant cells engurfing choresterol-crystals, and calcification. "Paraffinoma" was thus suspected, but there was no history of cosmetic mammoplasty and histochemical studies failed to demonstrate saturated lipid indicating paraffin or other mineral oils.


5. DOCID:7183 SCORE: 0.000250011025856898
DOCNO: 759469
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Sexual Behavior
QUALIFIER: radiotherapy
QUALIFIER: therapeutic use
QUALIFIER: radiotherapy
AUTHOR: H W Herr HW
PUBTYPE: Journal Article
JOURNALTITLE: Journal of the American Geriatrics Society.
COUNTRY: UNITED STATES
TITLE: Preservation of sexual potency in prostatic cancer patients after 125I implantation.
PUBDATE: 19790101
Sexual histories were obtained in 51 men with prostatic cancer and their spouses, before and after pelvic lymphadenectomy and retropubic 125I implantation. The average age of the patients was 64.7 years. Sexual activity was retained in 40 of the 41 patients who were sexually active before operation. Ten patients had been sexually inactive before operation--4 with diminished potency and 6 with complete erectile impotence. Sexual dysfunction was most often pyschogenic. At six months after the operation, 5 of these patients had resumed satisfactory sexual intercourse as a result of reassurance, encouragement and education of the remaining sexual potential. No patient was rendered completely impotent as a result of the procedure. Preservation of sexual potency represents a significant advantage of 125I implantation over other therapeutic modalities in the treatment of localized prostatic carcinoma.


6. DOCID:5269 SCORE: 0.000250010132897889
DOCNO: 498057
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Breast Neoplasms
QUALIFIER: secondary
AUTHOR: A DiStefano A
AUTHOR: Y Yong Yap Y
AUTHOR: G N Hortobagyi GN
AUTHOR: G R Blumenschein GR
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: The natural history of breast cancer patients with brain metastases.
PUBDATE: 19791101
One hundred one breast cancer patients with brain metastases (BM) were reviewed. The median survival from BM was 4.0 months. Seventy percent were receiving chemotherapy at the diagnosis of BM and 43% were showing a clinical response. Prolonged survival was seen in patients who underwent surgical resection, those with the brain as site of first metastasis, and those with a long free interval who survived the initial 5 months after BM. Long-term survivors (greater than 18 months from BM) demonstrated indolent disease by all parameters measured.


7. DOCID:5901 SCORE: 0.000250009186689461
DOCNO: 437915
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Lymphocyte Activation
QUALIFIER: biosynthesis
QUALIFIER: enzymology
AUTHOR: R Prasad R
AUTHOR: N Prasad N
AUTHOR: J E Harrell JE
AUTHOR: J Thornby J
AUTHOR: J H Liem JH
AUTHOR: P T Hudgins PT
AUTHOR: J Tsuang J
PUBTYPE: Journal Article
JOURNALTITLE: International journal of cancer. Journal international du cancer.
COUNTRY: DENMARK
TITLE: Aryl hydrocarbon hydroxylase inducibility and lymphoblast formation in lung cancer patients.
PUBDATE: 19790301
Aryl hydrocarbon hydroxylase (AHH) inducibility and lymphoblast formation were studied in lymphocytes from healthy control subjects and from lung cancer patients undergoing radiotherapy. The relationship between AHH inducibility and percentage lymphoblasts was statistically significant only for the pre-treatment patients (r = 0.598; p less than 0.05). In the control group and in patients undergoing radiotherapy the correlation between AHH inducibility and lymphoblast formation was positive but statistically it was not significant. Our data do not suggest a linear relationship between AHH inducibility and lymphoblast formation.


8. DOCID:4819 SCORE: 0.000250009009441394
DOCNO: 6973840
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiation effects
AUTHOR: B Fekete B
AUTHOR: J Petrányi J
AUTHOR: G Reischl G
AUTHOR: L Gyarmathy L
PUBTYPE: Journal Article
JOURNALTITLE: Strahlentherapie.
COUNTRY: GERMANY, WEST
TITLE: Short-term effect of irradiation on the peripheral lymphocyte populations in patients treated with high-energy photon beam.
PUBDATE: 19810801
Changes in lymphocyte populations wee studied in 22 patients with testicular cancer before and after a single 2-Hy dose of high-energy photon beam. Absolute lymphocyte counts as sell as total T-and active T cells markedly decreased immediately after irradiation, whereas no significant alterations in Fc receptor-bearing lymphocytes and B cell counts were produced. Recovery of lymphocyte populations was relatively rapid, reaching pre-irradiation values by 24 hours.


9. DOCID:6377 SCORE: 0.000250008978941727
DOCNO: 7362777
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug effects
QUALIFIER: pharmacology
AUTHOR: J S Senn JS
AUTHOR: C C Lai CC
AUTHOR: G B Price GB
PUBTYPE: Journal Article
JOURNALTITLE: British journal of cancer.
COUNTRY: ENGLAND
TITLE: Levamisole: evidence for activity on human haemopoietic progenitor cells.
PUBDATE: 19800101
Levamisole, which has immunostimulant activity, is now being used to treat some forms of cancer. We report that the drug enhances granulocyte colony formation. The mechanism of action appears to be partly through modulation of molecules on cell membranes. The molecular content of colony-stimulating activity (CSA) released into leucocyte-conditioned medium by cells of leukaemic and some preleukaemic patients can be quantitatively altered by levamisole, both in vitro and in vivo, but the CSA produced is qualitatively similar to that released by normal cells. The demonstrated levamisole enhancement of colony formation, and altered CSA types detected in leucocyte-conditioned medium, makes this drug a promising candidate for treatment of selected leukaemic states and in preleukaemia.


10. DOCID:4638 SCORE: 0.000250008356354768
DOCNO: 7414865
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
AUTHOR: K A Pavlov KA
AUTHOR: D P Volkov DP
PUBTYPE: Journal Article
JOURNALTITLE: Vestnik khirurgii imeni I. I. Grekova.
COUNTRY: USSR
TITLE: [Endoscopic diagnosis of colonic neoplasms]
PUBDATE: 19800601
The work analyzes results of complex examination of 88 patients with cancer of the large intestine. Correct diagnosis was made in 80 patients by fibrocolonoscopy combined with biopsy. The endoscopic method was found to have certain advantages over X-ray analysis for diagnosis of cancer of the large intestine especially in cases with small tumors. Complex employment of these methods was most efficient and allowed to make a true character of the disease in all the examined patients.


11. DOCID:4409 SCORE: 0.000250008178012964
DOCNO: 417188
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: adverse effects
QUALIFIER: drug effects
QUALIFIER: chemically induced
AUTHOR: V A Drill VA
AUTHOR: P L Golway PL
PUBTYPE: Journal Article
JOURNALTITLE: Journal of the National Cancer Institute.
COUNTRY: UNITED STATES
TITLE: Effect of ethynodiol diacetate with ethinyl estradiol on the mammary glands of rhesus monkeys: a preliminary report.
PUBDATE: 19780501
The oral contraceptive combination of ethynodiol diacetate with ethinyl estradiol (Demulen) was given cyclically to 48 female rhesus monkeys for 5 years. Doses employed were 1, 10, and 50 times the human dose. Treatment did not induce palpable breast nodules, and there were no deaths from mammary gland cancer.


12. DOCID:4818 SCORE: 0.000250007805923272
DOCNO: 7288052
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Food Preferences
QUALIFIER: adverse effects
QUALIFIER: psychology
AUTHOR: Z M Vickers ZM
AUTHOR: S S Nielsen SS
AUTHOR: A Theologides A
PUBTYPE: Journal Article
JOURNALTITLE: Journal of the American Dietetic Association.
COUNTRY: UNITED STATES
TITLE: Food preferences of patients with cancer.
PUBDATE: 19811001
Cancer patients who experience food aversions generally rated foods less pleasant than healthy controls or cancer patients with no food aversions. Most high protein foods, cereal products, and sweet foods were generally less palatable to patients with food aversions. Most fruits, vegetables, and cultured dairy products were equally palatable to all three subject groups. Although the cause of these food aversions is not understood, they do not appear to be a generalized response to all foods.


13. DOCID:6292 SCORE: 0.000250007803017054
DOCNO: 484789
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: R M Byers RM
AUTHOR: W W Krueger WW
AUTHOR: J Saxton J
PUBTYPE: Journal Article
JOURNALTITLE: American journal of surgery.
COUNTRY: UNITED STATES
TITLE: Use of surgery and postoperative radiation in the treatment of advanced squamous cell carcinoma of the pyriform sinus.
PUBDATE: 19791001
Forty-seven patients with very advanced cancer of the pyriform sinus were treated with surgery and immediate postoperative radiation in a planned sequential manner. Eradication of the cancer above the clavicles was obtained in 81% of the patients, with a treatment mortality of 8%. Most of the patients' tumors were resected with primary closure, which obviated the need for complicated reconstructive procedures. The survival rate of 23% at 2 years and the high rate of distant metastasis reflect the aggressive biologic behavior of this cancer. The need to find an adjuvant treatment that will act upon the systemic spread of this cancer is obvious.


14. DOCID:7323 SCORE: 0.00025000767323722
DOCNO: 508898
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: epidemiology
AUTHOR: J Faivre J
AUTHOR: C Milan C
AUTHOR: P Bugnon P
AUTHOR: J L Legoux JL
AUTHOR: F Martin F
AUTHOR: C Klepping C
PUBTYPE: Journal Article
JOURNALTITLE: Biomedicine / [publiée pour l'A.A.I.C.I.G.].
COUNTRY: FRANCE
TITLE: Primary liver cancer in Cote d'Or (Burgundy). Results of three year's systematic registration in a well defined French population.
PUBDATE: 19790901
The registry of digestive tract cancers set up for the department of Cote d'Or (455, 727) was used to study primary liver cancer. The crude annual incidence rate was 10.4 per 100 000 for males, 2.3 per 100 000 for females. Among other cancer registries annual age standardized rates: 7.6 per 100 000 in males, 1.4 per 100 000 in females are in the intermediate range, close to the figure reported in Geneva and higher than incidence rates reported elsewhere in Europe. Most cancers were hepatocullular carcinomas (83%). Significant etiological factors were the sex ratio (5, 4), alcoholic cirrhosis associated with primary liver cancer in 61% of the patients. The one year crude survival rate was 8%.