0. DOCID:9405 SCORE: 0.000250017894299735
DOCNO: 6233779
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: drug therapy
AUTHOR: J B deKernion JB
AUTHOR: A Lindner A
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The Urologic clinics of North America.
COUNTRY: UNITED STATES
TITLE: Chemotherapy of hormonally unresponsive prostatic carcinoma.
PUBDATE: 19840501
The national Prostatic Cancer Project has evaluated single and combination chemotherapeutic agents for the treatment of patients with advanced prostatic cancer that has been unresponsive to hormonal therapy. Although regression rates have been modest, a number of drugs have shown some efficacy and are now undergoing testing in combination. Current trials of the LH-RH agonists and the antiandrogen flutamide are in progress. These trials have demonstrated a role for chemotherapy in the treatment of the patient who has failed hormonal therapy.


1. DOCID:10297 SCORE: 0.000250015972505974
DOCNO: 6582324
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Neoplasms, Radiation-Induced
DESCRIPTOR: Ultraviolet Rays
QUALIFIER: chemically induced
QUALIFIER: pharmacology
QUALIFIER: chemically induced
AUTHOR: J H Epstein JH
PUBTYPE: Journal Article
JOURNALTITLE: Journal of the National Cancer Institute.
COUNTRY: UNITED STATES
TITLE: Effects of mechlorethamine (HN2, nitrogen mustard) on UV-induced carcinogenesis in hairless mouse skin.
PUBDATE: 19840201
The influence of mechlorethamine (HN2, nitrogen mustard) on UV-induced carcinogenesis was examined in the hairless mouse skin in vivo. Noncarcinogenic amounts of topically applied HN2 and carcinogenic levels of UVB energy were used in the study. The HN2 applications significantly accelerated the appearance and growth of cutaneous tumors in this study. Thus HN2 acted as either a promoter or cocarcinogen for UV-induced cancer formation. Although the mechanism of this effect was not established, combinations of UVB radiation and HN2 topical therapy pointed to an increased incidence of cutaneous tumors in human skin.


2. DOCID:15434 SCORE: 0.000250014321887307
DOCNO: 2824111
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analysis
QUALIFIER: immunology
AUTHOR: J L Vila JL
AUTHOR: C Juarez C
AUTHOR: I Illa I
AUTHOR: M Agusti M
AUTHOR: C Gelpi C
AUTHOR: M J Amengual MJ
AUTHOR: J L Rodriguez JL
AFFILIATION: Department of Immunology, Hospital de Sant Pau, Universitat Autonoma de Barcelona, Spain.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Clinical immunology and immunopathology.
COUNTRY: UNITED STATES
TITLE: Autoantibodies against the H1(0) subtype of histone H1.
PUBDATE: 19871201
The specificity of antinuclear autoantibodies in a patient with a sensory neuropathy associated with cancer has been analyzed. The autoantibodies recognize the histone H1(0) as shown by its dissociation from DNA, perchloric solubility, electrophoretic mobility in SDS or urea/acid polyacrylamide gels, and by the capacity of purified H1(0) to block the reactivity of these autoantibodies. Almost no reactivity was observed with other subtypes of H1. To our knowledge, this is the first autoantibody described with such specific reactivity for the H1(0) subtype.


3. DOCID:12987 SCORE: 0.000250013702361754
DOCNO: 3818819
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Antineoplastic Agents
DESCRIPTOR: Drug Evaluation, Preclinical
DESCRIPTOR: Drug Information Services
AUTHOR: M T Zehnacker MT
AUTHOR: R H Brennan RH
AUTHOR: G W Milne GW
AUTHOR: J A Miller JA
PUBTYPE: Journal Article
JOURNALTITLE: Journal of chemical information and computer sciences.
COUNTRY: UNITED STATES
TITLE: The NCI Drug Information System. 5. DIS Biology Module.
PUBDATE: 19861101
The NCI drug screening program tests over 10,000 chemicals per year for activity against cancer. The associated Drug Information System (DIS) captures all the raw testing data and provides for its validation. The large quantity of numeric data gathered during testing is maintained within the DIS in a database that is interactively searchable and automatically updated at regular intervals.


4. DOCID:12765 SCORE: 0.000250012291780973
DOCNO: 2769539
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: N S Adzick NS
AUTHOR: J H Fisher JH
AUTHOR: H S Winter HS
AUTHOR: R H Sandler RH
AUTHOR: W H Hendren WH
AFFILIATION: Department of Surgery, Children's Hospital, Boston, MA 02115.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Journal of pediatric surgery.
COUNTRY: UNITED STATES
TITLE: Esophageal adenocarcinoma 20 years after esophageal atresia repair.
PUBDATE: 19890801
We report a case of esophageal adenocarcinoma 20 years after esophageal atresia repair. From one case report it is premature to recommend cancer surveillance for all esophageal atresia patients. However, the first survivors are now reaching an age when esophageal cancer related to chronic esophagitis may become more prevalent.


5. DOCID:8886 SCORE: 0.000250011172740276
DOCNO: 6683630
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Lactates
DESCRIPTOR: Neoplasm Metastasis
QUALIFIER: etiology
QUALIFIER: complications
AUTHOR: J P Sculier JP
AUTHOR: C Nicaise C
AUTHOR: J Klastersky J
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: European journal of cancer & clinical oncology.
COUNTRY: ENGLAND
TITLE: Lactic acidosis: a metabolic complication of extensive metastatic cancer.
PUBDATE: 19830501
Lactic acidosis is a rare metabolic complication of cancer. An analysis of the cases reported in the English and French literature shows that all the patients have extensive neoplastic disease. Metastatic hepatic lesions are present in the large majority of cases, suggesting that alteration of liver function is part of the clinical picture. Chemotherapy against the neoplastic disease is the only effective treatment of this type of lactic acidosis.


6. DOCID:12274 SCORE: 0.000250009852397153
DOCNO: 2671728
AUTHOR: K Wrenn K
AFFILIATION: Department of Medicine, University of Rochester, NY.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The New England journal of medicine.
COUNTRY: UNITED STATES
TITLE: Fecal impaction.
PUBDATE: 19890901
Fecal impaction is a common disorder with variable presentation and many potential complications. Its pathophysiology is complex, and the treatment is often difficult and frustrating. Preventive measures are likely to be cost effective in populations at high risk, such as institutionalized or debilitated elderly people, mentally ill patients, those with chronic renal failure or cancer, and those who are neurologically impaired.


7. DOCID:8012 SCORE: 0.000250009781535091
DOCNO: 6375309
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: poisoning
QUALIFIER: chemically induced
QUALIFIER: chemically induced
AUTHOR: M Matsushima M
AUTHOR: K Ando K
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Hinyokika kiyo. Acta urologica Japonica.
COUNTRY: JAPAN
TITLE: [Biochemistry of occupational bladder cancer]
PUBDATE: 19831101
We herein discuss the biochemistry of occupational urinary tract cancer, by reviewing the history of occupational aromatic amine cancer, experimental production of aromatic amine cancers and aromatic amine double cancer.


8. DOCID:8239 SCORE: 0.000250009605380559
DOCNO: 7041841
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: H C Nohl-Oser HC
AUTHOR: A Fenn A
AUTHOR: V Dottori V
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: The Annals of thoracic surgery.
COUNTRY: UNITED STATES
TITLE: Tracheobronchoplastic procedure in the treatment of advanced carcinoma of the right upper lung.
PUBDATE: 19820401
Lung cancer of the right upper lobe not infrequently invades the right lower trachea. A tracheobronchoplastic procedure is described that makes it possible to reconstruct the tracheal defect after excision of the growth, while preserving the uninvolved lobes of the right lung.


9. DOCID:8902 SCORE: 0.00025000948725671
DOCNO: 3982372
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analysis
QUALIFIER: immunology
QUALIFIER: immunology
AUTHOR: T Yamada T
AUTHOR: Y Watanabe Y
AUTHOR: H Kimoto H
AUTHOR: T Iwa T
AUTHOR: S Okada S
AUTHOR: Y Kurata Y
PUBTYPE: Journal Article
JOURNALTITLE: Nippon Geka Gakkai zasshi.
COUNTRY: JAPAN
TITLE: [Studies on antigen highly associated with human bronchogenic squamous cell carcinoma--enzyme-linked immuno-absorbent assay]
PUBDATE: 19850201
Insoluble extracts of human bronchogenic squamous cell carcinoma were solubilized by desoxycholate. After fractionation, the soluble extracts were used to prepare antisera in guinea pigs. These antisera, after being highly absorbed with homogenates of several normal organ, serum and carcinoembryonic antigen, were reactive only with squamous cell carcinoma. There was no reactivity to fetal lung, normal adult organs or other cancers.


10. DOCID:15722 SCORE: 0.00025000944815087
DOCNO: 3674061
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: E J Seifter EJ
AUTHOR: M L Levitt ML
AUTHOR: B S Kramer BS
AFFILIATION: National Cancer Institute-Navy Medical Oncology Branch, Uniformed Services University for the Health Sciences, Bethesda, Maryland.
PUBTYPE: Journal Article
JOURNALTITLE: The American journal of medicine.
COUNTRY: UNITED STATES
TITLE: An outlier theory of cancer curability. Tumor cell differentiation as a therapeutic goal.
PUBDATE: 19871001
Combinations of cytotoxic agents that cure a substantial percentage of patients with several childhood and adult malignancies are much less efficacious for the majority of solid tumors. Standard approaches for curability that rely solely on the concept of cytotoxicity may not be applicable for most epithelial and mesenchymal solid malignancies. Differentiation may play a more important role in cancer cure than heretofore suspected. Clinical and experimental evidence supports further investigation into models of inducing tumor cell differentiation. The question of why such models could predict for curative modalities of treatment is discussed.


11. DOCID:8254 SCORE: 0.000250008930324641
DOCNO: 6859482
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: instrumentation
QUALIFIER: methods
QUALIFIER: surgery
AUTHOR: A M Duthie AM
PUBTYPE: Journal Article
JOURNALTITLE: Anaesthesia.
COUNTRY: ENGLAND
TITLE: Pituitary cryoablation.
PUBDATE: 19830501
Transphenoidal ablation of the pituitary gland by the injection of alcohol is used for the relief of wide-spread cancer pain. A technique is described in which a cryoprobe is passed through a transphenoidal needle and a number of lesions produced within the gland. It is suggested that this method of pituitary ablation may prove to be as effective but accompanied by fewer complications than the injection of alcohol.


12. DOCID:11224 SCORE: 0.000250008763701266
DOCNO: 6652603
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Nurse-Patient Relations
DESCRIPTOR: Psychiatry
DESCRIPTOR: Referral and Consultation
QUALIFIER: nursing
AUTHOR: G Taerk G
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Canadian journal of psychiatry. Revue canadienne de psychiatrie.
COUNTRY: CANADA
TITLE: Psychological support of oncology nurses: a role for the liaison psychiatrist.
PUBDATE: 19831101
This paper describes the working of an oncology nurses coping group which functioned under the guidance of a consultation-liaison psychiatrist at the Toronto General Hospital. Nurses were helped to deal more effectively with the many and varied stresses which they face in treating patients with cancer. As a result ward atmosphere, patient care and inter-staff communication improved. The success of the group was due to a number of factors that included the high motivation of the staff, the high level of stress on the ward, the support of the head nurse and the consistent relationship of the consulting psychiatrist. A series of cases are presented to illustrate these points.


13. DOCID:12141 SCORE: 0.000250008665220568
DOCNO: 3829017
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: adverse effects
QUALIFIER: adverse effects
QUALIFIER: etiology
AUTHOR: V F Holmes VF
AUTHOR: F Adams F
AUTHOR: F Fernandez F
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Cancer treatment reports.
COUNTRY: UNITED STATES
TITLE: Respiratory dyskinesia due to antiemetic therapy in a cancer patient.
PUBDATE: 19870401
Cancer patients commonly receive neuroleptics as antiemetics to relieve nausea and vomiting induced by chemotherapeutic agents. Respiratory dyskinesia, an infrequent, acute, neuroleptic-induced, dystonic reaction, is a potentially life-threatening entity that responds promptly to anticholinergic medication.


14. DOCID:12721 SCORE: 0.000250008401504243
DOCNO: 2560771
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: drug therapy
QUALIFIER: drug therapy
AUTHOR: F Kearns F
AUTHOR: L Grogan L
AUTHOR: P Harford P
AUTHOR: D N Carney DN
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Irish journal of medical science.
COUNTRY: IRELAND
TITLE: Resolution of small cell lung cancer intracranial metastases with standard dose chemotherapy.
PUBDATE: 19891201
Brain metastases are a well recognized problem in patients with small cell lung cancer (SCLC). Most patients are treated with whole brain cranial irradiation therapy which frequently improves symptoms. In this report we present data on two patients who achieved radiologically confirmed complete resolution of brain metastases treated with standard dose chemotherapy for SCLC.