0. DOCID:16003 SCORE: 0.000250023976473358
DOCNO: 1826844
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: methods
AUTHOR: R Karel-Brant R
PUBTYPE: Journal Article
JOURNALTITLE: Dermatology nursing / Dermatology Nurses' Association.
COUNTRY: UNITED STATES
TITLE: Periorbital skin cancers.
PUBDATE: 19910401
Mohs surgery is an excellent treatment for removal of periorbital skin cancers. Important structures and surrounding tissue may be preserved with this technique.

1. DOCID:24004 SCORE: 0.000250023934138709
DOCNO: 11682928
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Survival Rate
QUALIFIER: standards
QUALIFIER: standards
QUALIFIER: nursing
PUBTYPE: Journal Article
JOURNALTITLE: Clinical resource management.
COUNTRY: United States
TITLE: More educated nurses prove cost-effective for the sickest patients.
PUBDATE: 20011001
Follow-up by advanced practice nurses--as opposed to traditionally trained RNs--is associated with better outcomes among cancer patients.

2. DOCID:19587 SCORE: 0.000250023821599849
DOCNO: 1736473
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Genital Neoplasms, Male
DESCRIPTOR: Penile Neoplasms
DESCRIPTOR: Precancerous Conditions
DESCRIPTOR: Scrotum
AUTHOR: P F Schellhammer PF
AUTHOR: G H Jordan GH
AUTHOR: E L Robey EL
AUTHOR: J T Spaulding JT
AFFILIATION: Department of Urology, Eastern Virginia Medical School, Norfolk.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The Urologic clinics of North America.
COUNTRY: UNITED STATES
TITLE: Premalignant lesions and nonsquamous malignancy of the penis and carcinoma of the scrotum.
PUBDATE: 19920201
Premalignant lesions of the penis include cutaneous horn, balanitis xerotica obliterans, and leukoplakia. The true incidence of progression of each of these to squamous-cell carcinoma is unknown. Bowenoid papulosis, erythroplasia of Queyrat, and Bowen's disease are histologically identical to in situ carcinoma. Although the first is consistently benign, the latter two regularly evolve into invasive cancer. Malignant scrotal lesions include squamous-cell carcinoma, liposarcoma, leiomyosarcoma, basal-cell carcinoma, extramammary Paget's disease, erythroplasia of Queyrat, malignant melanoma, and metastases. Hemangioma can be confused with carcinoma.

3. DOCID:19300 SCORE: 0.000250021759025964
DOCNO: 8094712
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Gene Amplification
QUALIFIER: genetics
QUALIFIER: genetics
QUALIFIER: therapeutic use
AUTHOR: U Lönn U
AUTHOR: S Lönn S
AUTHOR: B Stenkvist B
AFFILIATION: Radiumhemmet, Karolinska Hospital, Stockholm, Sweden.
PUBTYPE: Journal Article
JOURNALTITLE: International journal of cancer. Journal international du cancer.
COUNTRY: UNITED STATES
TITLE: Reduced occurrence of mdr-1 amplification in stage-IV breast-cancer patients treated with tamoxifen compared with other endocrine treatments.
PUBDATE: 19930201
Amplification of mdr-1 occurs in breast cancer patients receiving endocrine treatment. We have compared a group of patients receiving tamoxifen and a group receiving second-line endocrine treatment after failure of tamoxifen treatment. Chronological tumor samples were obtained by fine-needle biopsies from the same tumor lesion of each patient and PCR was used to detect the appearance of gene amplification. Three of 20 patients receiving tamoxifen developed amplified mdr-1 whereas 7 of 17 patients receiving second-line endocrine treatment developed mdr-1 amplification.

4. DOCID:16005 SCORE: 0.00025002009188577
DOCNO: 8487233
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: chemically induced
QUALIFIER: adverse effects
QUALIFIER: adverse effects
AUTHOR: P J Maguire PJ
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The Journal of reproductive medicine.
COUNTRY: UNITED STATES
TITLE: Estrogen replacement therapy and breast cancer.
PUBDATE: 19930301
The safety of estrogen use in breast cancer patients is discussed. Most reports indicate there is no risk.

5. DOCID:27728 SCORE: 0.000250018193756397
DOCNO: 9848370
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: physiology
QUALIFIER: blood supply
QUALIFIER: physiopathology
AUTHOR: H M Pinedo HM
AUTHOR: H M Verheul HM
AUTHOR: R J D'Amato RJ
AUTHOR: J Folkman J
AFFILIATION: Department of Medical Oncology, Academic Hospital Vrije Universiteit, Amsterdam, The Netherlands.
PUBTYPE: Journal Article
JOURNALTITLE: Lancet.
COUNTRY: ENGLAND
TITLE: Involvement of platelets in tumour angiogenesis?
PUBDATE: 19981101
Preclinical and clinical research show that tumour growth is dependent on angiogenesis. Activation of the coagulation cascade is commonly found in patients with cancer. We propose that platelets contribute to tumour-induced angiogenesis. The basis of our hypothesis is that platelets are a rich source of stimulators and inhibitors of angiogenesis and their interaction with the endothelium. Presumably, the antithrombotic state of normal endothelium is disturbed by endothelial stimuli derived from tumour cells. This hypothesis may explain the suggested clinical benefits of anticoagulants in cancer and implies that targeting of platelet interaction with tumour vasculature will inhibit angiogenesis.

6. DOCID:9405 SCORE: 0.000250017894299735
DOCNO: 6233779
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: drug therapy
AUTHOR: J B deKernion JB
AUTHOR: A Lindner A
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The Urologic clinics of North America.
COUNTRY: UNITED STATES
TITLE: Chemotherapy of hormonally unresponsive prostatic carcinoma.
PUBDATE: 19840501
The national Prostatic Cancer Project has evaluated single and combination chemotherapeutic agents for the treatment of patients with advanced prostatic cancer that has been unresponsive to hormonal therapy. Although regression rates have been modest, a number of drugs have shown some efficacy and are now undergoing testing in combination. Current trials of the LH-RH agonists and the antiandrogen flutamide are in progress. These trials have demonstrated a role for chemotherapy in the treatment of the patient who has failed hormonal therapy.

7. DOCID:1938 SCORE: 0.000250017277049139
DOCNO: 865202
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
AUTHOR: C Gebhardt C
AUTHOR: D Moschinski D
AUTHOR: J Usmiani J
PUBTYPE: Journal Article
JOURNALTITLE: Langenbecks Archiv für Chirurgie.
COUNTRY: GERMANY, WEST
TITLE: [The treatment to the high gastric ulcer (author's transl)]
PUBDATE: 19770401
This is a report on 64 patients, who were operated on because of gastric ulcer situated near the cardia. We found the best results after the so-called step-like resection, which is preferable to selective vagotomy with excision of the ulcer and pyloroplasty because of the special conditions of the secretion of gastric juice in the case of high ulcers. Because of the danger of the development of a cancer in a B-II-stomach we prefer the B-I-anastomosis. For ulcers with stenosis of the esophagus a cardiofundectomy should be performed. Ulcers high on the greater curvature and in the fundus should be excised and a distal gastrectomy (B-I) should follow. The sole excision of the ulcer or the operation according to Kelling-Madlener are not recommended.

8. DOCID:21934 SCORE: 0.000250017121683647
DOCNO: 8854585
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: pathology
QUALIFIER: diagnosis
QUALIFIER: pathology
QUALIFIER: complications
AUTHOR: E Ichikawa E
AUTHOR: S Asano S
AUTHOR: S Okabe S
AUTHOR: M Itami M
AUTHOR: K Ohara K
AFFILIATION: Department of Dermatology, Doai Memorial Hospital, Tokyo, Japan.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of dermatology.
COUNTRY: JAPAN
TITLE: A case of cutaneous malignant fibrous histiocytoma.
PUBDATE: 19960801
A 54-year-old Japanese man with cutaneous malignant fibrous histiocytoma on the back is reported. He not only had a past history of thyroid cancer 1 year prior to the onset of the skin tumor, but also had simultaneous bladder cancer. Despite the early, wide resection, the prognosis was rapid and progressive. Histologically, the primary lesion of the skin tumor was difficult to differentiate from dermatofibrosarcoma protuberans; however, the recurrent and the metastatic lesions changed in appearance.

9. DOCID:24034 SCORE: 0.000250016407711069
DOCNO: 10101465
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: surgery
AUTHOR: W I Krasnodebski WI
AUTHOR: D Kopeć D
AFFILIATION: Katedry i Kliniki Chirurgii Gastroenterologicznej AM w Warszawie.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego.
COUNTRY: POLAND
TITLE: [Results of treatment of the cancer of the large intestine in elderly patients]
PUBDATE: 19980801
In the surgical management of colorectal cancer was disscussed and clinico-pathological features of prognostic significance were undelined.

10. DOCID:2974 SCORE: 0.000250016153875806
DOCNO: 169865
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: metabolism
QUALIFIER: biosynthesis
QUALIFIER: metabolism
AUTHOR: M S Al-Adnani MS
AUTHOR: J A Kirrane JA
AUTHOR: J O McGee JO
PUBTYPE: Journal Article
JOURNALTITLE: British journal of cancer.
COUNTRY: ENGLAND
TITLE: Inappropriate production of collagen and prolyl hydroxylase by human breast cancer cells in vivo.
PUBDATE: 19750601
Thirty-two scirrhous cancers of breast have been examined to determine the origin of the collagen stroma in these tumours. Employing two immunohistochemical techniques it has been shown that the malignant epithelial cells in 30 of these tumours contain not only collagen but also prolyl hydroxylase, a key enzyme in collagen biosynthesis. Neither this enzyme nor collagen was detectable in the spindle cells in the stroma of these tumours. Neither the epithelium in normal breast, that in fibrocystic disease and in fibroadenomata, nor the malignant epithelium in two medullary cancers of breast contained either collagen or prolyl hydroxylase. These results strongly suggest that the malignant epithelium of scirrhous breast cancers produces its own collagen stroma and that the scirrhous reaction in these tumours is not a host response to tumour invasion. The production of collagen and prolyl hydroxylase by breast cancer cells (of the scirrhous type) therefore represents another example of inappropriate protein production by a human tumour.

11. DOCID:10297 SCORE: 0.000250015972505974
DOCNO: 6582324
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Neoplasms, Radiation-Induced
DESCRIPTOR: Ultraviolet Rays
QUALIFIER: chemically induced
QUALIFIER: pharmacology
QUALIFIER: chemically induced
AUTHOR: J H Epstein JH
PUBTYPE: Journal Article
JOURNALTITLE: Journal of the National Cancer Institute.
COUNTRY: UNITED STATES
TITLE: Effects of mechlorethamine (HN2, nitrogen mustard) on UV-induced carcinogenesis in hairless mouse skin.
PUBDATE: 19840201
The influence of mechlorethamine (HN2, nitrogen mustard) on UV-induced carcinogenesis was examined in the hairless mouse skin in vivo. Noncarcinogenic amounts of topically applied HN2 and carcinogenic levels of UVB energy were used in the study. The HN2 applications significantly accelerated the appearance and growth of cutaneous tumors in this study. Thus HN2 acted as either a promoter or cocarcinogen for UV-induced cancer formation. Although the mechanism of this effect was not established, combinations of UVB radiation and HN2 topical therapy pointed to an increased incidence of cutaneous tumors in human skin.

12. DOCID:18816 SCORE: 0.000250015772396121
DOCNO: 2043699
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: immunology
QUALIFIER: immunology
AUTHOR: C Naftzger C
AUTHOR: A N Houghton AN
AFFILIATION: Memorial Sloan-Kettering Cancer Center, New York, New York.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Current opinion in oncology.
COUNTRY: UNITED STATES
TITLE: Tumor immunology.
PUBDATE: 19910201
The underlying premise of tumor immunology is that the immune system is capable of recognizing cancer cells and that immune recognition can lead to rejection of tumors by the host. We focus on recent advances in tumor immunology in experimental systems, including the molecular identification of tumor antigens, studies of recognition of tumor cells by the immune system, and the development of new strategies for treatment of cancer. Identifying potential target antigens on tumors and defining effector arms of the immune system that mediate tumor rejection (including T cells, natural killer cells, antibodies, complement cells, and cytokines) remain crucial problems for the field.

13. DOCID:229 SCORE: 0.000250015505290237
DOCNO: 1154620
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
AUTHOR: M A Zybina MA
AUTHOR: N N Nabatich NN
PUBTYPE: Journal Article
JOURNALTITLE: Vestnik khirurgii imeni I. I. Grekova.
COUNTRY: USSR
TITLE: [Results of combination therapy of rectal cancer]
PUBDATE: 19750601
A comparative study of the results of treatment in 264 patients treated surgically and in 236 patients subjected to a combination treatment, using an intensive concentration gammatherapy (500 rad daily up to 3000 rad), has demonstrated that preoperative irradiation does not result in a higher postoperative mortality. In the combination therapy all kinds of surgery performed for rectal cancer seem to be feasible.

14. DOCID:24215 SCORE: 0.000250015251097188
DOCNO: 9616560
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Critical Pathways
QUALIFIER: surgery
AUTHOR: R A Tucci RA
AUTHOR: K L Bartels KL
AFFILIATION: Lankenau Hospital, Main Health Systems, Wynnewood, PA, USA.
PUBTYPE: Journal Article
JOURNALTITLE: Clinical journal of oncology nursing.
COUNTRY: UNITED STATES
TITLE: Ovarian cancer surgery: a clinical pathway.
PUBDATE: 19980401
Clinical pathways are useful tools in providing quality care while decreasing the cost of that care. Pathways help to facilitate managed care, identify patient and family educational needs, encourage multidisciplinary communication, and expedite patient discharge. This article discusses a clinical pathway for ovarian cancer surgery.