0. DOCID:10092 SCORE: 0.00215240201174284
DOCNO: 4016675
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: complications
AUTHOR: R Kuylenstierna R
AUTHOR: E Munck-Wikland E
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Esophagitis and cancer of the esophagus.
PUBDATE: 19850801
Early diagnosis is an important factor in the effort to increase the healing rates of esophageal cancer; another consideration is the establishment of a reliable method of identifying risk groups. Alcohol abuse is known to be associated with a higher risk of esophageal cancer. The current investigation, based on a retrospective study of the records of patients with esophageal cancer, reveals a strong connection between cancer development and chronic esophagitis due mainly to reflux in about 10% of the patients. In the literature this connection has been suspected but never so clearly shown. The clinical implication may be a more rigorous approach to long-standing esophagitis in elderly patients.


1. DOCID:10012 SCORE: 0.00207589131045359
DOCNO: 6876400
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: cytology
QUALIFIER: diagnosis
AUTHOR: S Yamada S
AUTHOR: T Takeda T
AUTHOR: K Takaso K
AUTHOR: H Shinzawa H
AUTHOR: T Matsuda T
AUTHOR: H Saito H
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [Prognostic analysis of malignant peritoneal effusions from gastric cancer]
PUBDATE: 19830201
The prognosis of 135 cases with malignant peritoneal effusion from gastric cancer was analyzed clinically and cytologically. The histologic type of the primary gastric cancer or therapeutic differences had no significant influence on the prognosis. Previous gastrectomy or absence of distant metastases had no marked effect on survival. The formation of large clusters of cancer cells on smear preparations of peritoneal effusion was interpreted as a sign of good prognosis. The cancer cell number and the presence of lymphocytes on smear preparations bore no relationship to prognosis.


2. DOCID:11491 SCORE: 0.00179048834596845
DOCNO: 6292076
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Cell Division
DESCRIPTOR: Interphase
QUALIFIER: cytology
AUTHOR: C Diatloff-Zito C
AUTHOR: A Macieira-Coelho A
PUBTYPE: Journal Article
JOURNALTITLE: In vitro.
COUNTRY: UNITED STATES
TITLE: Effect of growth arrest on the doubling potential of human fibroblasts in vitro: a possible influence of the donor.
PUBDATE: 19820701
Population doublings versus time in culture were compared in human postnatal skin fibroblasts from normal donors, a cancer patient, and from donors suffering from Cockayne syndrome, Ataxia telangiectasia, and Fanconi's anemia (FA). Confluent cultures were maintained in a nonproliferating state for 14 to 27 d in 0.5% serum medium. The results show that the ability of cells to resume division after a resting stage can be influenced by pathologic conditions. In arrested FA cell populations an increase of the population doublings and of the calendar time were observed. It is possible that in some cell populations the resting stage favors the expression of growth potentialities related to instability of the cells.


3. DOCID:9765 SCORE: 0.00117208429544088
DOCNO: 2983952
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: mortality
AUTHOR: G C Roviaro GC
AUTHOR: F Varoli F
AUTHOR: P Zannini P
AUTHOR: A Fascianella A
AUTHOR: G Pezzuoli G
PUBTYPE: Journal Article
JOURNALTITLE: Chest.
COUNTRY: UNITED STATES
TITLE: Lung cancer in the young.
PUBDATE: 19850401
A long-term retrospective study was carried out on 1,514 cases of lung cancer to assess whether the disease presents substantial differences in young as compared to older patients. Clinical, epidemiologic, surgical, and survival data were evaluated in all cases. A young group under 45 years of age was studied separately and compared with the remaining older patients. In contrast with the literature, our results showed no percentage increase or variation in the male/female ratio of lung cancer in the young group. No significant difference was found regarding clinical picture, operability, histotype, and prognosis.


4. DOCID:10883 SCORE: 0.0011457720360492
DOCNO: 6538239
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: W E Dougherty WE
AUTHOR: J H Lynch JH
AUTHOR: W C Maxted WC
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of urology.
COUNTRY: UNITED STATES
TITLE: Case report: complete response of metastatic transitional cell carcinoma of the bladder with chemotherapy alone.
PUBDATE: 19840201
Transitional cell carcinoma of the bladder has remained to date basically a surgical disease with the addition of preoperative radiation therapy to increase survival. Chemotherapy for bladder cancer is administered either in an adjuvant setting or in patients with metastatic disease, most of whom have been treated already with cystectomy and/or radiation. We report a complete response at 54 months in a patient with clinical stage D2 and pathologic stage D1 carcinoma using cisplatin, doxorubicin and cyclophosphamide. The patient was treated with urinary diversion and chemotherapy alone, and no attempt was made to remove the primary lesion.


5. DOCID:10148 SCORE: 0.000863558691288996
DOCNO: 6723926
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Models, Biological
QUALIFIER: pharmacology
QUALIFIER: pharmacology
QUALIFIER: pharmacology
QUALIFIER: pharmacology
AUTHOR: I A Macdonald IA
AUTHOR: J A Mader JA
AUTHOR: B G Rao BG
AUTHOR: D A Malatjalian DA
PUBTYPE: Journal Article
JOURNALTITLE: Experientia.
COUNTRY: SWITZERLAND
TITLE: Model systems demonstrating the volatile mutagenicity and carcinogenicity of sodium nitrite in rats.
PUBDATE: 19840601
Volatile mutagens derived from sodium nitrite buffered at various pH values or in the presence of human feces were detected using Ames Salmonella tester strain TA 1535 on petrie plates inverted over samples. Volatile mutagenicity increased as the pH decreased and was primarily a function of the nitrous acid produced from sodium nitrite and hydrogen ions. Sodium nitrite administered intracecally to 3 Wistar rats through surgically implanted cannula caused tumors (fibrosarcoma: 1/3 and squamous cell, 2/3). The possible role of nitrite-derived mutagens in GI cancer is discussed.


6. DOCID:11661 SCORE: 0.000863555485040717
DOCNO: 3923296
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Electrocardiography
QUALIFIER: radiation effects
QUALIFIER: radiotherapy
AUTHOR: T V Blokhina TV
AUTHOR: B A Berdov BA
AUTHOR: V I Byrikhin VI
PUBTYPE: Journal Article
JOURNALTITLE: Meditsinskaia radiologiia.
COUNTRY: USSR
TITLE: [ECG changes during radiotherapy of stomach cancer]
PUBDATE: 19850501
Myocardial diffuse dystrophic changes were recorded on the ECG of patients with stomach cancer of different site. After a preoperative course of radiation therapy in the summary focal dose up to 24 Gy these changes were aggravated in 63% of cases: changes in the voltage of the QRS complex waves, amplitudes of P and T waves, S-T intervals and the heart rate were noted. The most pronounced ECG changes developed in patients with tumors in the proximal part of the stomach when radiation exposure of the heart corresponded to 100% of a focal dose. The voltage of the QRS complex waves decreased, the amplitude of P waves increased, a rise of the S-T interval was noted, the amplitude of T waves decreased.


7. DOCID:10169 SCORE: 0.000863525414226633
DOCNO: 7118615
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
AUTHOR: L L Doss LL
AUTHOR: N Memula N
PUBTYPE: Journal Article
JOURNALTITLE: International journal of radiation oncology, biology, physics.
COUNTRY: UNITED STATES
TITLE: The radioresponsiveness of melanoma.
PUBDATE: 19820701
The variability of malignant melanoma in its response to irradiation is well documented. Recent radiobiological studies suggest that high individual dose and low total fraction regimens will enhance the responsiveness of this tumor to irradiation. The experience of the Ellis Fischel State Cancer Hospital and the Cancer Research Center, Columbia, Missouri was reviewed with particular attention to such radiotherapeutic regimens. Of 41 lesions in 27 patients, the overall response rate to irradiation was 37%. When regimens using more than 400 cGy per fraction were analyzed, a 67% response rate was noted. Complete response and small volume of tumor correlated significantly (p = 0.008) with long-term survival.


8. DOCID:11273 SCORE: 0.000816194573486731
DOCNO: 6518451
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
AUTHOR: A M Watrach AM
AUTHOR: J A Milner JA
AUTHOR: M A Watrach MA
AUTHOR: K A Poirier KA
PUBTYPE: Journal Article
JOURNALTITLE: Cancer letters.
COUNTRY: NETHERLANDS
TITLE: Inhibition of human breast cancer cells by selenium.
PUBDATE: 19841101
The viability of human breast cancer cells (cell lines MCF-7 and MDA-MB 231) was inhibited in vitro in a dose-dependent manner by selenium supplementation. However, a normal diploid human cell line (MRC-5) was relatively resistant to selenium supplementation. The presence of selenium as Na2SeO3 at 1.1 X 10(-6) M reduced cancer cell viability by approximately 50%, whereas non-cancerous cells were not affected. Parenteral administration of sodium selenite also significantly inhibited the growth of the cancerous cell lines transplanted into nude mice. Selenium administration at 0.8 micrograms/g body wt resulted in an 80-93% reduction in the rate of tumor growth without apparent ill effects on the host.


9. DOCID:10798 SCORE: 0.000555136595279505
DOCNO: 4016711
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Catheters, Indwelling
QUALIFIER: administration & dosage
QUALIFIER: instrumentation
QUALIFIER: drug therapy
AUTHOR: M D Khoury MD
AUTHOR: L R Lloyd LR
AUTHOR: J Burrows J
AUTHOR: R Berg R
AUTHOR: J Yap J
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: A totally implanted venous access system for the delivery of chemotherapy.
PUBDATE: 19850901
The use of an Ommaya Capsule-Catheter System for the delivery of chemotherapy in cancer patients with inadequate peripheral veins has been studied over a 6-year period. Between 1978 and 1984, 76 Ommaya capsules were implanted in 68 patients, providing a collective experience of over 28,000 venous access days. Two patients were lost to follow-up. The results of the capsule-catheter system performance indicates a functional rate of over 90%. The complications included a 6.7% catheter occlusion rate, and a 2.7% capsule leakage rate. This accounts for an overall catheter related complication rate of 9.4%.


10. DOCID:11771 SCORE: 0.000555123763902144
DOCNO: 6676645
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analysis
QUALIFIER: blood
QUALIFIER: secondary
AUTHOR: K Shindo K
AUTHOR: T Mori T
AUTHOR: H Okuda H
AUTHOR: T Shimano T
AUTHOR: G Kosaki G
PUBTYPE: Journal Article
JOURNALTITLE: Nippon Geka Gakkai zasshi.
COUNTRY: JAPAN
TITLE: [Histopathological study on hepatic metastases and blood CEA levels in patients with intestinal carcinoma]
PUBDATE: 19830901
In 37% of 177 cases with colo-rectal cancer, our original staining method succeeded in the detection of cancer cells invaded in the small vein vessels in the primary lesion, 35.4% of which metastasized to the liver. Cancer cells were found histologically in the portal vein in these cases. Serum CEA levels were abnormally high in the cases of vein invasion in 57%. Hematogenic metastases occurred in 90% in the cases of vein invasion with abnormal CEA level. Serum CEA level decreased after the resection of the involved intestine, but increased sharply when hematogenic metastases occurred, while the CEA level increased gradually and slowly in cases of local recurrences or peritoneal disseminations .


11. DOCID:10147 SCORE: 0.000555105630424317
DOCNO: 6729812
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: physiopathology
QUALIFIER: pharmacology
QUALIFIER: physiopathology
AUTHOR: S Okuyama S
AUTHOR: M Sano M
AUTHOR: T Awano T
AUTHOR: S Takeda S
AUTHOR: K Yamada-Yokoyama K
AUTHOR: K Takahashi K
AUTHOR: T Matsuzawa T
PUBTYPE: Journal Article
JOURNALTITLE: The Tohoku journal of experimental medicine.
COUNTRY: JAPAN
TITLE: Gallium induces reduction of negative charge of the cell membrane and redifferentiation of cancer cells.
PUBDATE: 19840301
In order to obtain an insight into the mechanism of experimentally induced redifferentiation of cancer cells, changes in negative charge of the cell membrane were examined by cytopherometry following in vitro exposure of the cancer cells to non-radioactive gallium. Reduction of the negative charge was observed at 24 hr and later. The gallium ions must have neutralized the negative charge of the cancer cell membrane to the normal range. This event may contribute in some way to cancer cell redifferentiation.


12. DOCID:10374 SCORE: 0.00055508144215273
DOCNO: 6305855
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Cell Transformation, Viral
QUALIFIER: biosynthesis
QUALIFIER: metabolism
QUALIFIER: genetics
AUTHOR: J R Schlehofer JR
AUTHOR: L Gissmann L
AUTHOR: B Matz B
AUTHOR: H zur Hausen H
PUBTYPE: Journal Article
JOURNALTITLE: International journal of cancer. Journal international du cancer.
COUNTRY: DENMARK
TITLE: Herpes simplex virus-induced amplification of SV40 sequences in transformed Chinese hamster embryo cells.
PUBDATE: 19830701
Infection with Herpes simplex viruses (HSV) induces amplification of SV40 sequences in SV40-transformed Chinese hamster embryo cells (CO631). This is shown by in situ hybridization of the infected cells with cloned 32P-labelled SV40 DNA. The HSV-mediated synthesis of SV40 DNA is more pronounced than after treatment with chemical carcinogens. This initiator-like effect of HSV may, in concert with the previously reported mutagenic activity of this virus (Schlehofer and zur Hausen, 1982), point to a possible mechanism of HSV infection in human genital cancer.


13. DOCID:9114 SCORE: 0.000555077377053802
DOCNO: 6293068
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radionuclide imaging
QUALIFIER: secondary
AUTHOR: J Mensch-Dechêne J
AUTHOR: D Silbert D
AUTHOR: M Merlier M
PUBTYPE: Journal Article
JOURNALTITLE: La semaine des hôpitaux : organe fondé par l'Association d'enseignement médical des hôpitaux de Paris.
COUNTRY: FRANCE
TITLE: [Isotopic scintigraphy in the diagnosis of the spread of bronchial cancer]
PUBDATE: 19820901
Ventilation of the lungs using Xenon 133 and perfusion scans using 99m Tc albumin particles in microspheres were performed on 455 patients with bronchial cancers and 55 patients with pulmonary metastases. Ventilation-perfusion mismatch and functional defects of the lung, which are never found in nodular-shaped pulmonary metastases, vary in frequency according to the anatomo-pathological type of the tumor and constitute a limiting factor for ablation.


14. DOCID:10723 SCORE: 0.000555056975626733
DOCNO: 4032759
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Gastrectomy
QUALIFIER: pathology
AUTHOR: T Sugawara T
AUTHOR: A Ouchi A
AUTHOR: K Kawakami K
AUTHOR: K Shiiba K
AUTHOR: N Ebina N
AUTHOR: H Ito H
AUTHOR: F Shimizu F
AUTHOR: F Kuroda F
AUTHOR: T Sato T
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [Clinicopathological study of a malignant lesion in the remnant stomach]
PUBDATE: 19850601
Thirty-six cases of malignant lesion in the remnant stomach were studied clinicopathologically. Ten had been surgically managed as benign lesions and eight were suspected of being metachronous multiple gastric cancer. The pathological characteristics of the malignant lesions and the operation interval (mostly more than 10 years) were similar in these two groups. Although malignant lesion in the remnant stomach is difficult to differentiate clearly when there is no sufficient histological evidence, the operation interval of more than 10 years can be one of the criteria for differential diagnosis.