0. DOCID:13274 SCORE: 0.00204367405461295
DOCNO: 2973369
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: analogs & derivatives
AUTHOR: L Schwartz L
AUTHOR: N Guiochet N
AUTHOR: R Keiling R
AFFILIATION: Service de Radiotherapie, CHU Strasbourg, France.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Two partial remissions induced by an LHRH analogue in two postmenopausal women with metastatic breast cancer.
PUBDATE: 19881201
We report two cases of metastatic breast cancer occurring in two postmenopausal women. Treatment with a luteinizing hormone-releasing hormone (LHRH) analogue, D-TRP6-LHRH, induced partial remission. The blood levels of the follicle stimulating hormone (FSH) and luteinizing hormone (LH) fell sharply under treatment, but the levels of estradiol, estriol, and estrone did not change significantly. We also described the putative mechanisms of action of the LHRH analog.


1. DOCID:12931 SCORE: 0.00203940397998565
DOCNO: 3683959
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: P Ghiron P
AUTHOR: I Dato I
AUTHOR: M Giudici M
AFFILIATION: Ospedale degli Infermi, Divisione di Urologia, U.S.S.L. n. 47, Biella, Vercelli.
PUBTYPE: Journal Article
JOURNALTITLE: Minerva medica.
COUNTRY: ITALY
TITLE: [Aspecific granulomatous prostatitis. Our experience]
PUBDATE: 19871101
The clinical and anatomopathological features of 7 personally observed cases of granulomatous prostatitis are described. The possibility of confusion between this pathology and cancer of the prostate is pointed out. This is particularly the case when the entire gland is inflammed and only bioptic examination will confirm the diagnosis. The symptoms mostly related to the cervicourethral obstruction, the diagnostic procedure and the treatment, prevalently medical, adopted in each are described.


2. DOCID:14841 SCORE: 0.00195736109834465
DOCNO: 2722574
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Surgical Flaps
QUALIFIER: pathology
QUALIFIER: transplantation
QUALIFIER: surgery
QUALIFIER: pathology
QUALIFIER: surgery
QUALIFIER: pathology
AUTHOR: M Vollrath M
AUTHOR: G Reiss G
AFFILIATION: HNO-Klinik, Medizinischen Hochschule Hannover.
PUBTYPE: Journal Article
JOURNALTITLE: HNO.
COUNTRY: GERMANY, WEST
TITLE: [Submicroscopic changes in the jejunum in ectopic sites. A scanning and transmission electron microscopy study following free, microvascular jejunum transfer]
PUBDATE: 19890401
Biopsies of the jejunal epithelium were analysed by scanning and transmission electron microscopy of specimens taken from patients at least 1 year after reconstruction of defects from resection of oro-hypopharyngeal cancer by free microvascular anastomized jejunum graft. The villi were compressed and flattened, their surface uneven due to calibre changes of columnar cells. The microvilli were rarefied and grossly altered. In the subapical area there was a distinct enhancement of desmosomal connections. Paneth cells and endocrine cells were unaltered. Autonomic nerves were intact, though the muscularis mucosa seemed to be denervated.


3. DOCID:14036 SCORE: 0.00183472539315382
DOCNO: 3599468
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: physiology
QUALIFIER: etiology
AUTHOR: Y Tagashira Y
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [The role of cytochrome P-450 in chemical carcinogenesis--its application to human cancer epidemiology]
PUBDATE: 19870401
Most chemical carcinogens require metabolic activation before they exert their deleterious effects on an organism. This overview shows the evidence that most chemical carcinogens are metabolically activated by specific P-450 isozymes and the induction of these enzymes plays an important role in chemical carcinogenesis. On the other hand, there is circumstantial evidence from a large number of animal experiments implicating that human susceptibility to environmental cancer may be affected by genetic predisposition for drug metabolism. On the basis of these findings, several problems in application to human cancer epidemiology were pointed out.


4. DOCID:14484 SCORE: 0.00173927544180639
DOCNO: 2715019
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Thyroidectomy
QUALIFIER: surgery
QUALIFIER: physiopathology
QUALIFIER: physiopathology
QUALIFIER: physiopathology
QUALIFIER: surgery
QUALIFIER: physiopathology
AUTHOR: C Kull C
AUTHOR: M Breu M
AUTHOR: M Hoffmann M
AUTHOR: W W Rittmann WW
PUBTYPE: Journal Article
JOURNALTITLE: Helvetica chirurgica acta.
COUNTRY: SWITZERLAND
TITLE: [Paralyses of the recurrent laryngeal nerve following strumectomy in late follow-up]
PUBDATE: 19890101
Over a period of 5 years, 323 patients underwent an operation on a goiter. A postoperative paralysis of the recurrent laryngeal nerve occurred in 31 patients, most in malignancies and recurrent goiters. 26 patients were controlled at least 1 year after operation. 65% of the patients have a fully recovered voice and normal vocal cord function. Another 14% showed a normal voice for daily use by functional compensation of the paralysis. Only in 4 patients (16%) the operation resulted in a permanent modest or severe hoarseness as consequence of a thyroidectomy in cancer.


5. DOCID:13975 SCORE: 0.00168722078423192
DOCNO: 3614955
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: etiology
AUTHOR: P N Watson PN
AUTHOR: R J Evans RJ
PUBTYPE: Journal Article
JOURNALTITLE: Pain.
COUNTRY: NETHERLANDS
TITLE: Intractable pain with lung cancer.
PUBDATE: 19870501
This study examines retrospectively the natural history, classification, clinical and pathological features and results of treatment of intractable pain associated with lung cancer in 221 patients. The 3 chief causes of malignancy-related pain were skeletal metastatic disease (34%), Pancoast's tumour (31%) and chest wall disease (21%), together comprising 78% of the cancer-related pain problems. The median interval between cancer diagnosis and pain onset was 1 month. Overall pathological types of cancer were similar to those of lung cancer in general. Treatment modalities were varied and included radiation, percutaneous cordotomy, regional deafferentation and pharmacotherapy. The median survival from pain onset was 10 months.


6. DOCID:13090 SCORE: 0.00165449313399153
DOCNO: 2959486
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: A Jakobsen A
AUTHOR: K Bertelsen K
AUTHOR: A Sell A
AFFILIATION: Institute of Cancer Research, Danish Cancer Society, Aarhus, Denmark.
PUBTYPE: Journal Article
JOURNALTITLE: European journal of cancer & clinical oncology.
COUNTRY: ENGLAND
TITLE: Cyclic hormonal treatment in ovarian cancer. A phase-II trial.
PUBDATE: 19870701
Twenty-nine patients with advanced epithelial ovarian cancer were included in a phase-II trial of cyclic hormonal treatment. The schedule consisted of tamoxifen 10 mg X 3 daily for 14 days followed by medroxyprogesterone acetate 400 mg X 2 daily for 14 days. No objective response was recorded in 17 evaluable patients and cyclic hormonal treatment appears to be ineffective in advanced ovarian cancer.


7. DOCID:13078 SCORE: 0.00165449109743694
DOCNO: 3566126
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Disease Models, Animal
QUALIFIER: chemically induced
QUALIFIER: chemically induced
QUALIFIER: chemically induced
QUALIFIER: chemically induced
AUTHOR: J M Gilbert JM
PUBTYPE: Journal Article
JOURNALTITLE: Annals of the Royal College of Surgeons of England.
COUNTRY: ENGLAND
TITLE: Experimental colorectal cancer as a model of human disease.
PUBDATE: 19870301
Colorectal cancer may now be induced consistently in experimental animals by the carcinogen 1,2-dimethylhydrazine (DMH). Adenomas and adenocarcinomas are produced in the large bowel and these resemble human colorectal cancer both macroscopically, and in their clinical behaviour. They are a close model of human disease and may be used for the evaluation of anti-cancer therapies and for the development of a diagnostic test for colorectal cancer.


8. DOCID:13318 SCORE: 0.00162739227594587
DOCNO: 2768914
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: radiography
QUALIFIER: surgery
QUALIFIER: radiography
AUTHOR: T Fujisawa T
AUTHOR: N Iwai N
AUTHOR: A Kashiwaya A
AUTHOR: Y Saitoh Y
AUTHOR: C Kadoyama C
AUTHOR: Y Yamaguchi Y
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: [Zasshi] [Journal]. Nihon Kyōbu Geka Gakkai.
COUNTRY: JAPAN
TITLE: [The diagnostic value of computed tomography during lymphangiography on the postoperative chylothorax in lung cancer]
PUBDATE: 19890201
A successfully operated case of postoperative chylothorax in a lung cancer was reported, under the diagnosis of computed tomography during lymphangiography demonstrating the disruption of the thoracic duct. The computed tomography during lymphangiography is considered to be very useful for deciding the surgical indication of postoperative chylothorax and prompt surgical treatment is recommended when the main truncus of the thoracic duct is lacerated.


9. DOCID:15039 SCORE: 0.00161751379135467
DOCNO: 3828965
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: genetics
QUALIFIER: genetics
AUTHOR: D Ehrenthal D
AUTHOR: L Haeger L
AUTHOR: T Griffin T
AUTHOR: C Compton C
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Familial pancreatic adenocarcinoma in three generations. A case report and a review of the literature.
PUBDATE: 19870501
Although scattered case reports of familial clustering of pancreatic cancer have appeared in the literature, hereditary factors have not been clearly associated with increased risk for this malignancy. The current report documents the familial occurrence of pancreatic adenocarcinoma in three women of consecutive generations who died of their disease at progressively younger ages. The diagnoses are histologically confirmed in all three cases. Although two of the women carried a single known risk factor for pancreatic carcinoma (cigarette smoking), a familial predisposition to this disease is strongly implicated. The case suggests that the role of inheritance in pancreatic carcinoma may merit further exploration.


10. DOCID:14035 SCORE: 0.00161345662800625
DOCNO: 3599476
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Contraceptive Devices, Male
QUALIFIER: prevention & control
AUTHOR: M Mori M
AUTHOR: H Miyake H
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [Possible reduction of cervical cancer by the use of barrier-type contraceptives]
PUBDATE: 19870601
Forty-four cervical cancer inpatients and 44 individually age-matched controls were surveyed. As a result, the number of the cases whose partners used condoms for contraception was significantly lower than that of the controls (P less than 0.01; the odds ratio = 0.2). The same result was obtained after adjusting possible confounding variables such as the number of pregnancies and use of other contraceptive methods. Barrier-type contraceptives like condoms may reduce the incidence of sexually transmitted viral infections, which it has been suggested are associated with the disease.


11. DOCID:13389 SCORE: 0.00160608051348058
DOCNO: 3290496
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Immunity, Cellular
DESCRIPTOR: Immunologic Surveillance
QUALIFIER: immunology
AUTHOR: M L Kripke ML
AFFILIATION: Department of Immunology, University of Texas System Cancer Center, M. D. Anderson Hospital and Tumor Institute, Houston 77030.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Journal of the National Cancer Institute.
COUNTRY: UNITED STATES
TITLE: Immunoregulation of carcinogenesis: past, present, and future.
PUBDATE: 19880701
Twenty years ago the concept that immunological mechanisms might regulate carcinogenesis was highly controversial. Today this concept survives in modified form and continues to evolve as our knowledge of the immune system, the etiology of cancer, and tumor antigens expands. This review illustrates how our ideas about immune surveillance have changed in recent years and considers the significance of these changes for the future directions of cancer immunobiology.


12. DOCID:15879 SCORE: 0.00159043460531015
DOCNO: 2650528
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Blood Transfusion
DESCRIPTOR: Neoplasm Recurrence, Local
AUTHOR: P I Tartter PI
AFFILIATION: Department of Surgery, Mount Sinai Medical Center, New York, New York 10029.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: American journal of clinical oncology : the official publication of the American Radium Society.
COUNTRY: UNITED STATES
TITLE: Does blood transfusion predispose to cancer recurrence?
PUBDATE: 19890401
Retrospective studies of the relationship between perioperative blood transfusion and cancer recurrence are reviewed. Control for variables related to blood transfusion and potentially affecting disease recurrence--anemia, blood loss, duration of surgery, magnitude of the procedure, and stage of disease--was notably absent from the majority of studies. None of the negative studies had sufficient number of both transfused and untransfused patients to answer the question with statistical validity. No consensus emerged regarding the significance of blood transfusion for the cancer patient and no recommendations concerning the use of blood in patients with malignancies are justified on the basis of these studies.


13. DOCID:14146 SCORE: 0.00158933905612408
DOCNO: 2645985
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
AUTHOR: M E Boyd ME
AFFILIATION: Department of Obstetrics and Gynecology, Royal Victoria Hospital, Montreal, PQ.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Canadian journal of surgery. Journal canadien de chirurgie.
COUNTRY: CANADA
TITLE: Endometrial cancer.
PUBDATE: 19890301
Abdominal hysterectomy will cure cancer of the endometrium confined to the body of the uterus. If the tumour has spread beyond the uterus, adjuvant therapy will be needed. The likelihood of such spread can be predicted from postoperative histologic examination of the uterus or discovered by surgical staging. Surgical staging does not appear to be curative or to reduce the need for adjuvant therapy. Prognosis depends on the grade and location of the tumour in the uterus and the extent of invasion into the myometrium or beyond the uterus, and not on the removal of occult metastases.


14. DOCID:14713 SCORE: 0.00157061593409937
DOCNO: 3277009
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
AUTHOR: V K Titov VK
AUTHOR: M A Kaplan MA
AUTHOR: V Iu Sloventator VIu
AUTHOR: V V Shakhtarin VV
AUTHOR: Ia M Khmelevskiĭ IaM
PUBTYPE: Journal Article
JOURNALTITLE: Meditsinskaia radiologiia.
COUNTRY: USSR
TITLE: [Radionuclide evaluation of postoperative catabolism in breast cancer]
PUBDATE: 19880101
The paper is concerned with the results of investigation of the body composition and albumin circulation using a method of whole-body radiometry, extracellular liquid volume--by a 40K-RP, the level of cortisol, T3, insulin, C-peptide in the blood plasma by a radioimmunoassay in 30 breast cancer patients. A decrease in cellular body mass, an increase in extracellular body mass and total body fat, a decrease in the sizes of all pools and albumin synthesis rate were revealed before the initiation of specific cancer therapy. Ten days after the discontinuation of therapy the above indices returned to normal.