0. DOCID:22865 SCORE: 0.00306088908170675
DOCNO: 9365848
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: blood
QUALIFIER: diagnosis
QUALIFIER: blood
QUALIFIER: diagnosis
AUTHOR: N Segawa N
AUTHOR: K Yamamoto K
AUTHOR: T Watsuji T
AUTHOR: T Suzuki T
AUTHOR: H Ueda H
AUTHOR: Y Katsuoka Y
AFFILIATION: Department of the Urology, Osaka Medical College.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Hinyokika kiyo. Acta urologica Japonica.
COUNTRY: JAPAN
TITLE: [Ureteral cancer producing carbohydrate antigen 19-9: report of a case]
PUBDATE: 19970901
A case of a CA19-9-producing ureteral cancer is reported. A 58-year-old man presented with gross hematuria. Retrograde pyelography showed an irregular filling defect in the right ureter. The serum CA19-9 level was 932 U/ml (normal < 37). Right total nephroureterectomy was performed. The histological diagnosis was grade 3 transitional cell carcinoma. Immunohistochemical analysis showed CA19-9 to be expressed not only in the cancer cells but also in the normal transitional cell epithelium of the renal pelvis.


1. DOCID:27008 SCORE: 0.00298578458015471
DOCNO: 11778749
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: methods
AUTHOR: V Nwakakwa V
AUTHOR: D Fleischer D
AFFILIATION: Division of Gastroenterology, Georgetown University Medical Center, Washington, DC 20007, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Gastrointestinal endoscopy clinics of North America.
COUNTRY: United States
TITLE: Endoscopic mucosal resection of the esophagus: band ligation technique.
PUBDATE: 20010701
Endoscopic mucosal resection (EMR) is a minimally invasive endoscopic technique used in treating superficial cancers of premalignant lesions in the gastrointestinal tract. An attraction of this technique is that it can be curative with low morbidity, often providing the entire lesion for pathologic evaluation. The band ligation technique of EMR uses the existing technology of variceal band ligation to endoscopically place a band on flat mucosal lesions of the gastrointestinal tract to create a "pseudopolyp" before resection with an electrocautery snare. The band ligating technique and two variant band ligating devices are described.


2. DOCID:22120 SCORE: 0.00272615671759745
DOCNO: 8838100
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Chromosomes, Human, Pair 3
DESCRIPTOR: Genes, Tumor Suppressor
QUALIFIER: genetics
AUTHOR: K Hibi K
AUTHOR: T Takahashi T
AFFILIATION: Laboratory of Ultrastructure Research, Nagoya University School of Medicine.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Nippon rinsho. Japanese journal of clinical medicine.
COUNTRY: JAPAN
TITLE: [Positional-cloning efforts to identify the tumor suppressor gene at 3p]
PUBDATE: 19960201
Lung cancer is known to carry multiple cytogenetic alterations. Among such chromosomal abnormalities, deletions at the short arm of chromosome 3 has been shown to be the most frequent and can be detected even in hyperplasia of the bronchial epithelium, suggesting its important roles in the pathogenesis of lung cancer. In this chapter, we describe current status of the positional-cloning attempts to identify the target tumor suppressor gene at 3p in our laboratories as well as in other laboratories.


3. DOCID:22172 SCORE: 0.00272615422119305
DOCNO: 7849530
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Brain
DESCRIPTOR: Gene Transfer Techniques
AUTHOR: L J Fisher LJ
AUTHOR: J Ray J
AFFILIATION: Department of Neurosciences, University of California San Diego, La Jolla 92093-0627.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Current opinion in neurobiology.
COUNTRY: ENGLAND
TITLE: In vivo and ex vivo gene transfer to the brain.
PUBDATE: 19941001
The use of gene transfer techniques to express novel proteins within different cellular populations has provided insights into the function and plasticity of the brain. Recently, this technique has been successfully used to explore physiological processes within the CNS and to intervene in neurodegenerative disease and cancer. Progress in manipulating transgene products in vivo and in achieving cell-specific targeting of genetic material offers promise for enhancing the usefulness of this technique and its therapeutic potential for treating human disorders of the CNS.


4. DOCID:23719 SCORE: 0.00254247163310041
DOCNO: 9317183
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Pharmacokinetics
DESCRIPTOR: Pharmacology, Clinical
QUALIFIER: metabolism
AUTHOR: R E Vestal RE
AFFILIATION: Department of Veterans Affairs Medical Center, and Mountain States Medical Research Institute, Boise, Idaho 83702, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Aging and pharmacology.
PUBDATE: 19971001
Research on aging and pharmacology in humans has been termed geriatric clinical pharmacology, which is an established subdiscipline within the broad field of clinical pharmacology. This article reviews information relevant to clinical cancer research and the care of older patients with cancer. Accordingly, the current state of knowledge on drug utilization, pharmacokinetics, pharmacodynamics, adverse drug events, drug interactions, polypharmacy, adherence to treatment, and clinical research considerations are reviewed. Although a review of the literature on aging and cancer chemotherapy is not included in this particular presentation, information is very sparse. Thus, there is significant potential for valuable contributions from clinical research through partnerships between geriatric clinical pharmacologists and medical oncologists.


5. DOCID:26039 SCORE: 0.00251496345421108
DOCNO: 11338019
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: genetics
AUTHOR: D S Schrump DS
AUTHOR: D M Nguyen DM
AFFILIATION: Thoracic Oncology Section, Surgery Branch, National Cancer Institute, National Institutes of Health, Building 10, Room 2B-07, 10 Center Drive, Bethesda, Maryland 20892-1502, USA. david_schrump@nih.gov
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: World journal of surgery.
COUNTRY: United States
TITLE: Targets for molecular intervention in multistep pulmonary carcinogenesis.
PUBDATE: 20010201
Lung cancers are a leading cause of mortality worldwide, and most of these neoplasms are directly attributable to tobacco abuse. Recent studies have begun to elucidate molecular mechanisms of multistep aero-digestive tract carcinogenesis, revealing novel targets for intervention in lung cancers and their precursor lesions. This review summarizes the molecular biology of lung cancers in relation to the prognosis and treatment of patients with these neoplasms.


6. DOCID:24716 SCORE: 0.00251377796329813
DOCNO: 11343961
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: secondary
QUALIFIER: secondary
QUALIFIER: pathology
AUTHOR: D Carroll D
AUTHOR: P B Rajesh PB
AFFILIATION: Department of Thoracic Surgery, Birmingham Heartlands Hospital, Bordesley Green East, B9 5SS, Birmingham, UK. danderosier@doctors.org.uk
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.
COUNTRY: England
TITLE: Colonic metastases from primary squamous cell carcinoma of the lung.
PUBDATE: 20010501
Lung cancer is the most common malignancy in the UK. Metastasis to the colon is very rare and only infrequently symptomatic. Here we report a case of squamous cell carcinoma of the lung which presented with symptoms from a colonic metastasis.


7. DOCID:25410 SCORE: 0.00250815244015644
DOCNO: 10751464
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiography
QUALIFIER: methods
AUTHOR: K D Hopper KD
AUTHOR: K Singapuri K
AUTHOR: A Finkel A
AFFILIATION: Department of Radiology, Penn State University, Hershey, PA 17033, USA. khopper@psu.esu
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Radiology.
COUNTRY: UNITED STATES
TITLE: Body CT and oncologic imaging.
PUBDATE: 20000401
The most commonly used imaging modality in patients with cancer is computed tomography (CT). Whether to evaluate primary tumor or metastases to the neck, chest, abdomen, or pelvis, oncologic body CT has become invaluable to medical, gynecologic, and radiation oncologists. CT is the principal tool used to stage tumor, assess response, and guide radiation therapy. This review provides a discussion of how we optimize oncologic CT to best meet the needs of the patient with cancer.


8. DOCID:28930 SCORE: 0.00246438876268239
DOCNO: 15691805
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: genetics
AUTHOR: Somkiat Sunpaweravong S
AUTHOR: Patrapim Sunpaweravong P
AFFILIATION: Department of Surgery, Prince of Songkla University, Hat Yai, Songkla 90110, Thailand. susomkia@medicine.psu.ac.th
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Asian journal of surgery / Asian Surgical Association.
COUNTRY: China
TITLE: Recent developments in critical genes in the molecular biology of breast cancer.
PUBDATE: 20050101
The biology of breast cancer is complex, and the increasing knowledge of its molecular biology is having a great impact on the clinical management of this serious condition. This review looks at new findings on the role of various critical genes, including BRCA1, BRCA2, HER2 and p53, in the development of breast cancer and their clinical implications.


9. DOCID:30518 SCORE: 0.00240780100512058
DOCNO: 14763130
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analogs & derivatives
QUALIFIER: therapeutic use
QUALIFIER: antagonists & inhibitors
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: John Lyons J
AUTHOR: Emel Bayar E
AUTHOR: Gil Fine G
AUTHOR: Michael McCullar M
AUTHOR: Randee Rolens R
AUTHOR: Joseph Rubinfeld J
AUTHOR: Craig Rosenfeld C
AFFILIATION: jlyons1@ireland.com
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Current opinion in investigational drugs (London, England : 2000)
COUNTRY: England
TITLE: Decitabine: development of a DNA methyltransferase inhibitor for hematological malignancies.
PUBDATE: 20031201
Decitabine (DAC) is a small molecule nucleotide analog that is incorporated into DNA and traps human DNA methyltransferases. Although initially developed as a cytotoxic agent, low-dose DAC is enjoying a revival as a specific inhibitor of hypermethylation in cancer. DAC has activity in several hematological diseases, especially myelodysplastic syndrome, chronic myelogenous leukemia and acute myeloid leukemia. Clinical and preclinical advances are presented in this review.


10. DOCID:30602 SCORE: 0.00240779942123737
DOCNO: 15649275
OWNER: NLM
STATUS: In-Data-Review
AUTHOR: Mary J Feeney MJ
AFFILIATION: Los Altos, California, USA.
PUBTYPE: Journal Article
JOURNALTITLE: Clinical and experimental pharmacology & physiology.
COUNTRY: Australia
TITLE: Fruits and the prevention of lifestyle-related diseases.
PUBDATE: 20041201
SUMMARY 1. Fruits contain a variety of compounds that may slow or prevent chronic diseases through a variety of possible mechanisms. Components in fruits thought to be associated with the reduction of these conditions include soluble and insoluble dietary fibre, anti-oxidant nutrients (vitamins C, E, selenium, beta-carotene) and phytonutrients (bioactive plant compounds that impart colour, flavour and other functional properties to foods). 2. The present paper briefly reviews selected studies on the role of some fruits in lifestyle conditions such as cardiovascular disease, some types of cancer and conditions that accompany ageing.


11. DOCID:23474 SCORE: 0.0023222548663001
DOCNO: 8015827
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Immunosuppression
QUALIFIER: etiology
QUALIFIER: adverse effects
QUALIFIER: etiology
QUALIFIER: etiology
AUTHOR: B Nemes B
AUTHOR: N Lázár N
AUTHOR: J Járay J
AFFILIATION: Semmelweis OTE II, Pathologiai Intézet.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Orvosi hetilap.
COUNTRY: HUNGARY
TITLE: [Simultaneous occurrence of transplantation glomerulopathy, malignant Hodgkin lymphoma and lip cancer in a patient under immunosuppressive treatment]
PUBDATE: 19940601
Authors reported on transplantation glomerulopathy (TGP), occurred in a patient's cadaver kidney allograft, as well as on orchitis, lymphogranulomatosis (Hodgkin's lymphoma) and lip cancer detected thereafter in the same patient. While TGP was definitely be verified morphologically, all other observed diseases are commonly and typically met with membranous glomerulopathy (MGP), which is a separate entity. Similar case has not yet been reported in the literature. Since in majority of the cases the MGP is a paraneoplastic phenomenon, and the TGP is a part of chronic rejection in kidney allografts the differential diagnosis may have therapeutic consequences.


12. DOCID:31112 SCORE: 0.00223102570362584
DOCNO: 12420862
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: chemically induced
QUALIFIER: pathology
AUTHOR: H M Turk HM
AUTHOR: C Camci C
AUTHOR: S Buyukberber S
AUTHOR: B Tuncozgur B
AUTHOR: C Sivrikoz C
AUTHOR: L Elbeyli L
AUTHOR: I Sari I
AFFILIATION: Gaziantep University, Faculty of Medicine, Department of Medical Oncology, Turkey.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Journal of chemotherapy (Florence, Italy)
COUNTRY: Italy
TITLE: Superior vena cava syndrome caused by chemotherapy-induced fibrosis.
PUBDATE: 20020801
We report a case of a 51-year old man with small cell lung cancer who developed superior vena cava syndrome due to obstruction of the superior vena cava at the junction of the brachiocephalic vein by a fibrotic band, 2 months after completing six cycles of chemotherapy with cisplatin and etoposid. Superior vena cava syndrome caused by chemotherapy-induced pulmonary fibrosis should be kept in mind during follow-up.


13. DOCID:27051 SCORE: 0.00206423211073278
DOCNO: 10974622
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
QUALIFIER: metabolism
QUALIFIER: metabolism
AUTHOR: M J Piccart MJ
AUTHOR: A Di Leo A
AUTHOR: A Hamilton A
AFFILIATION: Institut Jules Bordet, Unite de Chimiotherapie, Rue Héger Bordet 1, B-1000, Brussels, Belgium. mpiccart@ulb.ac.be
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: European journal of cancer (Oxford, England : 1990)
COUNTRY: ENGLAND
TITLE: HER2. a 'predictive factor' ready to use in the daily management of breast cancer patients?
PUBDATE: 20000901
The past few years have witnessed an exponential increase in studies trying to identify molecular markers in patients with breast tumours that might predict for the success or failure of hormonal therapy or chemotherapy. HER2, a tyrosine kinase membrane receptor of the epidermal growth factor receptor family, has been the most widely studied marker in this respect. This paper attempts to critically review to what extent HER2 may improve 'treatment individualisation' for the breast cancer patient.


14. DOCID:26992 SCORE: 0.00205080738221085
DOCNO: 9651707
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Mass Screening
QUALIFIER: physiopathology
QUALIFIER: prevention & control
AUTHOR: J V McMurray JV
AUTHOR: T A McDonagh TA
AUTHOR: A P Davie AP
AUTHOR: J G Cleland JG
AUTHOR: C M Francis CM
AUTHOR: C Morrison C
AFFILIATION: MRC CRI in Heart Failure, University of Glasgow, U.K.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: European heart journal.
COUNTRY: ENGLAND
TITLE: Should we screen for asymptomatic left ventricular dysfunction to prevent heart failure?
PUBDATE: 19980601
A programme to detect and treat asymptomatic left ventricular dysfunction would seem to fulfil all five principles of screening. Indeed, such a programme would appear to be at least as firmly based as those already in existence for, for example, cervical and breast cancer. Further evaluation of the screening of high risk groups to detect asymptomatic left ventricular systolic dysfunction with the aim of giving treatment to prevent the development of heart failure is merited.