0. DOCID:25641 SCORE: 0.00502790731650289
DOCNO: 11894692
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Anus Diseases
DESCRIPTOR: Condylomata Acuminata
AUTHOR: S Sultan S
AFFILIATION: Service de Coloproctologie, Hôpital des Diaconesses, 18, rue du Sergent-Bauchat, F 75012 Paris.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Journal de chirurgie.
COUNTRY: France
TITLE: [Anal condyloma: its management is still difficult]
PUBDATE: 20011001
Anal condylomas result from papillomavirus infection, the most common sexually transmitted disease. The principal risk is the development of cancer of the anal canal. The risk of contamination is high, even after a single sexual contact. No specific antiviral treatment is available and no consensus has been reached on the appropriate treatment of anal condylomas. Despite the development of various methods (interferon, imiquimod), electrocoagulation remains the treatment of choice. Finally, regular follow-up and treatment of the partner(s) are essential.

1. DOCID:26228 SCORE: 0.00500703306504518
DOCNO: 10753784
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: genetics
QUALIFIER: genetics
QUALIFIER: genetics
AUTHOR: J Jiricny J
AUTHOR: M Nyström-Lahti M
AFFILIATION: Institute of Medical Radiobiology of the University of Zürich, Paul Scherrer Institute, Zürich, CH-8008, Switzerland. jiricny@imr.unizh. ch
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Current opinion in genetics & development.
COUNTRY: ENGLAND
TITLE: Mismatch repair defects in cancer.
PUBDATE: 20000401
Post-replicative mismatch repair in humans utilises the hMSH2, hMSH6, hMSH3, hMLH1 and hPMS2 genes and possibly the newly identified hMLH3 gene. Recently, a link has been established between hMSH6 mutations and 'atypical' hereditary non-polyposis colon cancer (HNPCC) with an increased incidence of endometrial cancers. To satisfy the need for a diagnostic test capable of differentiating between pathogenic mutations and polymorphisms, several functional assays that fulfil these criteria have been described. These should allow for better diagnosis of HNPCC.

2. DOCID:25465 SCORE: 0.00435838926009138
DOCNO: 11071453
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: therapy
AUTHOR: T Kakizoe T
AFFILIATION: National Cancer Center Hospital, Tokyo, Japan. tkakizoe@ncc.go.jp
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: World journal of surgery.
COUNTRY: UNITED STATES
TITLE: Urologic oncology in the twenty-first century.
PUBDATE: 20001001
The perspective of urologic oncology in the twenty-first century is presented regarding detection, treatment, and prevention of cancer. There is increasing importance of a cancer information network. Biotechnology and medical engineering based on advances in computer science will be the two key technologies related to such advancement. Ethical, legal, social, and economic issues provoked by the technologic advances will increase in gravity at the same time. Balancing humans in terms of scientific technologic developments and state of mind will be a serious issue.

3. DOCID:25936 SCORE: 0.00408919671670484
DOCNO: 9555165
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: secondary
QUALIFIER: pathology
AUTHOR: E Lengyel E
AUTHOR: A Somogyi A
AUTHOR: T Molnár T
AUTHOR: E Tóth E
AUTHOR: E Remenár E
AUTHOR: Z Skriba Z
AUTHOR: O Esik O
AFFILIATION: Országos Onkológiai Intézet, Sugárterápiás Osztály és Haynal Imre Egészségtudományi Egyetem Sugárterápiaś Tanszék, Budapest.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Orvosi hetilap.
COUNTRY: HUNGARY
TITLE: [Juvenile aneuploid papillary cancer of the thyroid with pulmonary metastasis]
PUBDATE: 19980301
The long-term cause-specific survival results of papillary thyroid cancer patients in Hungary are (78%) worse than the best international data (90%). The authors have recited its causes through the case of a young papillary thyroid cancer patient during the diagnostics (aspiration cytology, diagnostic imaging technics, DNA-analysis) the treatment (surgery-external radiotherapy-radioiodine treatment) and the follow-up (HTG, diagnostic imaging).

4. DOCID:27267 SCORE: 0.00381547183066053
DOCNO: 11048437
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Societies, Medical
DESCRIPTOR: Thoracic Surgical Procedures
QUALIFIER: pathology
QUALIFIER: methods
AUTHOR: T Shirakusa T
AFFILIATION: Second Department of Surgery, School of Medicine, Fukuoka University, Japan.
PUBTYPE: Journal Article
JOURNALTITLE: Kyobu geka. The Japanese journal of thoracic surgery.
COUNTRY: JAPAN
TITLE: [Postoperative results under the new stage classification of lung cancer: the additional reports for those of JACS in 1996]
PUBDATE: 20001001
This time, in 3008 lung cancer patients, the postoperative results were analyzed under the new stage grouping of TNM classification. All of those patients underwent the operation in 1989, and the 5 year-survival rates had beeb surveyed in 1996 by JACS (The Japanese Association for Chest Surgery). Under the new TNM classification established in 1996 worldwidey, T3N0M0 was transferred from IIIA to IIB. This report is the additional one in the focus of the results accompanied with the change of TNM classification.

5. DOCID:26984 SCORE: 0.00376999761862019
DOCNO: 9832032
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Mutation
DESCRIPTOR: Tumor Suppressor Proteins
QUALIFIER: genetics
QUALIFIER: genetics
AUTHOR: M Longy M
AUTHOR: V Coulon V
AUTHOR: B Duboué B
AUTHOR: A David A
AUTHOR: M Larrègue M
AUTHOR: C Eng C
AUTHOR: P Amati P
AUTHOR: J L Kraimps JL
AUTHOR: A Bottani A
AUTHOR: D Lacombe D
AUTHOR: D Bonneau D
AFFILIATION: Laboratoire d'Oncologie Moléculaire, Institut Bergonié, Bordeaux, France.
PUBTYPE: Journal Article
JOURNALTITLE: Journal of medical genetics.
COUNTRY: ENGLAND
TITLE: Mutations of PTEN in patients with Bannayan-Riley-Ruvalcaba phenotype.
PUBDATE: 19981101
We report three new mutations in PTEN, the gene responsible for Cowden disease in five patients with Bannayan-Riley-Ruvalcaba syndrome from three unrelated families. This finding confirms that Cowden disease, a dominant cancer predisposing syndrome, and Bannayan-Riley-Ruvalcaba syndrome, which includes macrocephaly, multiple lipomas, intestinal hamartomatous polyps, vascular malformations, and pigmented macules of the penis, are allelic disorders at the PTEN locus on chromosome 10q.

6. DOCID:26320 SCORE: 0.00341674217849816
DOCNO: 10753587
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: metabolism
QUALIFIER: metabolism
QUALIFIER: physiology
AUTHOR: B R Lackey BR
AUTHOR: S L Gray SL
AUTHOR: D M Henricks DM
AFFILIATION: Endocrine Physiology Laboratory, Department of Animal and Veterinary Sciences, Clemson University, Clemson, SC 29634, USA. blackey@clemson.edu
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.
COUNTRY: SCOTLAND
TITLE: Actions and interactions of the IGF system in Alzheimer's disease: review and hypotheses.
PUBDATE: 20000201
Insulin-like growth factors (IGF) are pleiotrophic polypeptides affecting all aspects of growth and development. The IGF system, including ligands, receptors, binding proteins and proteases is also involved in pathophysiological conditions, such as cancer and degenerative conditions. In this review, the actions and interactions of the IGF system as it relates to Alzheimer's disease will be investigated.

7. DOCID:25677 SCORE: 0.00293648186467267
DOCNO: 10805108
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: immunology
AUTHOR: M Drlicek M
AUTHOR: A Bodenteich A
AUTHOR: U Setinek U
AUTHOR: G Tucek G
AUTHOR: S Urbanits S
AUTHOR: W Grisold W
AFFILIATION: Ludwig Boltzmann Institut für Neuroonkologie, Linz, Austria. marcus.drlicek@wj.lkh.ooe.gv.at
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Acta neuropathologica.
COUNTRY: GERMANY
TITLE: T cell-mediated paraneoplastic ganglionitis--an autopsy case.
PUBDATE: 20000501
A 57-year-old woman presented with subacute sensory, ataxic neuronopathy. Clinical investigation revealed a right-sided non-small-cell lung cancer. Serum investigation for specific antineuronal antibodies was negative. Histology showed T lymphocytic infiltrates in dorsal root ganglia. The observed histological pattern is similar to that described in antibody-positive cases. Thus, these findings suggest similar pathways in specific antineuronal antibody-negative and -positive cases of paraneoplastic subacute sensory neuronopathy.

8. DOCID:27917 SCORE: 0.00268609915568732
DOCNO: 10950461
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: genetics
AUTHOR: R W Burt RW
AFFILIATION: Department of Medicine, University of Utah, College of Medicine, and Huntsman Cancer Institute, Salt Lake City, USA.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Seminars in gastrointestinal disease.
COUNTRY: UNITED STATES
TITLE: Rare syndromes and genetic testing for colorectal cancer.
PUBDATE: 20000701
The genes responsible for each of the inherited syndromes of intestinal polyposis and colorectal cancer are now known. This knowledge has led to genetic testing for syndrome diagnosis and for determining which persons in an affected family actually have the condition. Genetic testing has also allowed a more precise clinical characterization of each of the syndromes and their subtypes. Optimal application of genetic testing, proper cancer prevention, and management of nonmalignant features of each of the syndromes are the next goals. This report summarizes each of the syndromes, their genetics, and management and provides an approach for genetic testing.

9. DOCID:27419 SCORE: 0.00253596700478863
DOCNO: 15825357
OWNER: NLM
STATUS: In-Process
AUTHOR: H Liu H
AUTHOR: X Deng X
AUTHOR: W Fang W
AFFILIATION: Beijing Normal University, Department of Physics, 100875 Beijing.
PUBTYPE: Journal Article
JOURNALTITLE: Guang pu xue yu guang pu fen xi = Guang pu.
COUNTRY: China
TITLE: [A study on the spectra of L-fucose]
PUBDATE: 19981001
The concentration of L-fucose will extraordinarily increase in urine in patients with early stage of cancer. It seems that this is a significant clue for early phase diagnosis of cancer. Unfortunately the sensitive detection of L-fucose is difficult. Thus we carried out researches on IR-spectrum, Raman spectrum, ultraviolet absorption spectrum and ultraviolet fluorescence spectrum. We compared the results from patients and healthy subjects. It is confirmed that the spectroscopic method, especially ultraviolet fluorescence spectrophotometry, may be suitable for early stage screening of some kinds of cancer. This test is rapid, inexpensive and painless.

10. DOCID:27852 SCORE: 0.00249489452259209
DOCNO: 9702406
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
AUTHOR: J M Stewart JM
AUTHOR: J R Zalcberg JR
AFFILIATION: Department of Hematology and Medical Oncology, Peter MacCallum Cancer Institute, Melbourne, Australia.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Current opinion in oncology.
COUNTRY: UNITED STATES
TITLE: Update on adjuvant treatment of colorectal cancer.
PUBDATE: 19980701
Developments in the adjuvant therapy of colorectal cancer have been reported recently. Important questions regarding the most appropriate regimen, the optimal duration of treatment, the preferred route of administration, and which subgroups are most likely to benefit are addressed. A number of studies in rectal cancer considered the timing of chemoradiation, mode of administration of chemotherapy, and the role of intraoperative radiotherapy. Quality of life issues also are being addressed. Several new agents and novel therapies have produced interesting and, it is hoped, clinically useful results. The prognostic significance of a number of molecular markers also is the subject of ongoing research.

11. DOCID:27014 SCORE: 0.00248364283668089
DOCNO: 11684440
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Cell Hypoxia
DESCRIPTOR: Neovascularization, Pathologic
QUALIFIER: pathology
QUALIFIER: metabolism
AUTHOR: C Brahimi-Horn C
AUTHOR: E Berra E
AUTHOR: J Pouysségur J
AFFILIATION: Institute of Signaling, Developmental Biology and Cancer Research, CNRS UMR 6543, Centre A. Lacassagne, 33 Avenue Valombrose, 06189 Nice, France. brahimi@unice.fr
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Trends in cell biology.
COUNTRY: England
TITLE: Hypoxia: the tumor's gateway to progression along the angiogenic pathway.
PUBDATE: 20011101
Decreased aerobic (hypoxic) conditions in tumors induce the release of cytokines that promote vascularization and thereby enhance tumor growth and metastasis. Recent major advances have provided insight into the role hypoxia plays in cancer biology. The domain structure of the hypoxia-inducible factor 1alpha (HIF-1alpha) has been elucidated, as has the mechanism by which stabilization of HIF-1alpha leads to initiation of the transcription of target genes involved in growth of blood vessels.

12. DOCID:27436 SCORE: 0.00228625984182239
DOCNO: 11531185
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: etiology
QUALIFIER: surgery
QUALIFIER: complications
QUALIFIER: complications
QUALIFIER: diagnosis
AUTHOR: J J Ridgeway JJ
AUTHOR: C Pettigrew C
AUTHOR: D G Gallup DG
AUTHOR: J J Burke JJ
AUTHOR: F H Weber FH
AFFILIATION: Department of Obstetrics and Gynecology, Memorial Health University Medical Center, Savannah, GA 31403, USA.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Southern medical journal.
COUNTRY: United States
TITLE: Recurrent ascites and pleural effusions after surgery for early-stage endometrial adenocarcinoma.
PUBDATE: 20010701
A case of massive postoperative ascites in a woman treated for endometrial cancer is reported. A workup for typical causes of ascites yielded negative results, prompting a more detailed analysis of the patient's condition. Hypothyroidism was discovered. After correction of the hypothyroidism, the ascites slowly resolved. Since myxedema is an uncommon cause of ascites, this is usually a diagnosis of exclusion. However, hypothyroidism must be ruled out to prevent unnecessary and possibly inappropriate treatments for ascites.

13. DOCID:25754 SCORE: 0.00199025303803946
DOCNO: 10479265
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Mind-Body Relations (Metaphysics)
QUALIFIER: psychology
QUALIFIER: psychology
AUTHOR: E T Creagan ET
AFFILIATION: Mayo Clinic, Rochester, MN 55905, USA. creagan.edward@mayo.edu
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The Journal of prosthetic dentistry.
COUNTRY: UNITED STATES
TITLE: Attitude and disposition: Do they make a difference in cancer survival?
PUBDATE: 19990901
STATEMENT OF PROBLEM: Investigators have attempted to resolve the question: do psychosocial, emotional, and attitudinal factors have any effect on cancer survival? PURPOSE: This article presents a literature review and an overview of the developments in the mind-body connection to examine the influence of attitude in cancer survival. CONCLUSION: Even though a causal effect of emotional issues on the initiation and promotion of cancer is speculative, the effect of emotions on numerous medical conditions cannot be ignored.

14. DOCID:26432 SCORE: 0.00173077183883183
DOCNO: 9777922
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Drug Therapy, Combination
QUALIFIER: drug therapy
AUTHOR: P M Doraiswamy PM
AUTHOR: D C Steffens DC
AFFILIATION: Department of Psychiatry and Behavioral Sciences and the Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, North Carolina 27710, USA.
PUBTYPE: Journal Article
JOURNALTITLE: Journal of the American Geriatrics Society.
COUNTRY: UNITED STATES
TITLE: Combination therapy for early Alzheimer's disease: what are we waiting for?
PUBDATE: 19981001
The practical pharmacological approaches currently available to palliate the cognitive and functional losses in early Alzheimer's disease (AD) include cholinesterase inhibitors (ChEI), antioxidants (e.g., vitamin E), anti-inflammatory agents, estrogen, seligiline, vasoactive agents, and ginkgo biloba. Reviewing available data on these therapies and using models from medical illnesses such as cancer and hypertension, we highlight the urgent need for evaluating combination therapies in early AD.