0. DOCID:18826 SCORE: 0.00754796004068924
DOCNO: 1699401
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: analogs & derivatives
AUTHOR: D D Von Hoff DD
AUTHOR: S Green S
AUTHOR: E A Surwit EA
AUTHOR: E V Hannigan EV
AUTHOR: D S Alberts DS
AFFILIATION: University of Texas Health Science Center, San Antonio 78284-7884.
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
PUBTYPE: Multicenter Study
JOURNALTITLE: American journal of clinical oncology : the official publication of the American Radium Society.
COUNTRY: UNITED STATES
TITLE: Phase II study of fludarabine phosphate (NSC 312887) in patients with advanced cervical cancer. A Southwest Oncology Group study.
PUBDATE: 19901001
Twenty evaluable patients with advanced cervical cancer refractory to one prior chemotherapy regimen were treated with a 5-day schedule of fludarabine phosphate. No responses were noted. The major toxicities were anemia and leukopenia. Based on this study, fludarabine phosphate does not appear to be an active agent for patients with chemotherapy refractory cervical cancer.

1. DOCID:18634 SCORE: 0.00604349605673443
DOCNO: 1526834
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: M L Jekić ML
AUTHOR: I M Jekić IM
AFFILIATION: Klinisches Krankenhaus, Zemun-Belgrade, Jugoslawien.
PUBTYPE: Journal Article
JOURNALTITLE: Helvetica chirurgica acta.
COUNTRY: SWITZERLAND
TITLE: [Effect of chemotherapy on survival in advanced breast cancer]
PUBDATE: 19920501
Survival time of 119 consecutive patients with metastasizing carcinoma of the breast who had been treated with various chemotherapeutic schedules after radical operation was determined retrospectively. 57 women received chemotherapy and hormones, as well as radiotherapy, while 62 had radiotherapy plus hormone treatment. The mean prolongation of life in the former group over that of the latter was 12 months (p less than 0.01). Although chemotherapy delayed death, the dynamics of cancer were not fundamentally affected. The chemotherapy-induced prolongation (2.5 months to five years) was independent of any risk, primary location of the metastases or age.

2. DOCID:19209 SCORE: 0.00472785667722608
DOCNO: 1306436
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: X M Cui XM
AFFILIATION: School of Stomatology, Beijing Medical University.
PUBTYPE: Journal Article
JOURNALTITLE: Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology.
COUNTRY: CHINA
TITLE: [Effect of connective tissues underlying precancerous lesions combined with epithelia separated from normal mucosa]
PUBDATE: 19920901
The connective tissues underlying the precancerous changes of the epithelia were separated and combined with the epithelia which were separated from the normal mucosa. The combinations were transplanted in nude mice. Specimens were taken at 6 and 10 weeks after transplantation and routinely processed for microscopic examination. The results show that the connective tissue underlying epithelial dysplasia may induce the normal epithelium undergoing epithelial dysplasia changes. The experiment demonstrates the etiological importance of the connective tissue in the development of cancer, and may be applied clinically in the treatment of precancerous lesions.

3. DOCID:18780 SCORE: 0.00436995355179419
DOCNO: 12797274
OWNER: NLM
STATUS: PubMed-not-MEDLINE
AUTHOR: B Breyer B
AUTHOR: A Despot A
AUTHOR: M Predanic M
AUTHOR: S Judin S
AFFILIATION: Gynaecological Cancer Centre, Petrova 13, Zagreb, Croatia.
PUBTYPE: Journal Article
JOURNALTITLE: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.
COUNTRY: England
TITLE: Characteristics of blood flow in cancer of the uterine cervix.
PUBDATE: 19930701
Blood flow characteristics were measured in patients with histologically proved cervical cancer and compared to normal values. Flow parameters were derived by color and pulsed Doppler ultrasound. The results showed a significant difference in the mean values of resistance index and pulsatility index among the diseased patients and healthy controls. However, the method does not have the required sensitivity for screening purposes, so that its value may mainly be in the follow-up of patients treated conservatively with radiation and chemotherapy.

4. DOCID:18524 SCORE: 0.00426063942288992
DOCNO: 2269234
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Cocarcinogenesis
QUALIFIER: adverse effects
QUALIFIER: etiology
QUALIFIER: etiology
AUTHOR: R G Stevens RG
AUTHOR: D R Kalkwarf DR
AFFILIATION: Pacific Northwest Laboratory, Richland, WA 99352.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Environmental health perspectives.
COUNTRY: UNITED STATES
TITLE: Iron, radiation, and cancer.
PUBDATE: 19900701
Increased iron content of cells and tissue may increase the risk of cancer. In particular, high available iron status may increase the risk of a radiation-induced cancer. There are two possible mechanisms for this effect: iron can catalyze the production of oxygen radicals, and it may be a limiting nutrient to the growth and development of a transformed cell in vivo. Given the high available iron content of the western diet and the fact that the world is changing to the western model, it is important to determine if high iron increases the risk of cancer.

5. DOCID:17548 SCORE: 0.00408327700241196
DOCNO: 1852047
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Kidney Transplantation
QUALIFIER: diagnosis
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: D Hannibal D
AUTHOR: W Gross-Fengels W
AUTHOR: U Hesse U
AFFILIATION: Institut und Poliklinik für Radiologische Diagnostik, Universität zu Köln.
PUBTYPE: Journal Article
JOURNALTITLE: RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin.
COUNTRY: GERMANY
TITLE: [Malignant tumors of the normotopic kidneys and ureters following kidney transplantation]
PUBDATE: 19910501
There is an 4.2-23% incidence of cancer in renal transplant recipients. A closely meshed radiological follow-up is important as shown in 3 patients who developed a carcinoma of the kidney or ureter within 1-5 years after renal transplantation. This includes routine sonography of the whole abdomen, in case of pathological findings CT respectively MRI, i.v. urography, retrograde urography and angiography if needed.

6. DOCID:17500 SCORE: 0.00367728166789354
DOCNO: 2328479
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
AUTHOR: D E Henson DE
AUTHOR: L A Ries LA
AFFILIATION: Division of Cancer Prevention and Control, National Cancer Institute, Bethesda, MD 20892.
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Progress in early breast cancer detection.
PUBDATE: 19900501
Evidence indicates progress in the early detection of breast cancer. After 1982 there was a reported increase in the incidence of breast cancer, presumably as a result of increased screening for the disease. The increase was especially noted in early stage breast cancer. The incidence of in situ cases also increased. Since 1973 the San Francisco-Oakland Bay area has reported a statistically significant decrease in mortality for white women. The evidence supports continued efforts at early breast cancer detection.

7. DOCID:18862 SCORE: 0.00348723556918373
DOCNO: 1306969
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: methods
AUTHOR: M Abbes M
AUTHOR: C Boursault C
AUTHOR: D Conso D
AUTHOR: E Roméo E
AFFILIATION: Centre Antoine-Lacassagne, Nice.
PUBTYPE: Journal Article
JOURNALTITLE: Annales de chirurgie plastique et esthétique.
COUNTRY: FRANCE
TITLE: [Forum: dermopigmentation or medical tattooing. Dermography in cancerology. Apropos of 220 clinical cases]
PUBDATE: 19920801
Based on a series of 220 cases of reconstruction (63 cases) or correction (67 cases) of the nipple-areolar complex and various extramammary procedures (tattoo scar revision, lips, eyebrows, eyelashes) (90 cases), the authors present their 2-year experience of medical dermography in a cancer centre. Dermography allows breast reconstruction to be completed in a large number of patients who had initially refused to complete their reconstruction. This minimally aggressive outpatient technique which reconstitutes the areolo-nipple complex with sufficient quality, is now part of reconstruction protocols and is gradually replacing surgical techniques.

8. DOCID:18078 SCORE: 0.00336741026885229
DOCNO: 1942992
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: complications
QUALIFIER: complications
QUALIFIER: etiology
QUALIFIER: etiology
QUALIFIER: complications
AUTHOR: T P Iakimova TP
AUTHOR: O V Dolgaia OV
PUBTYPE: Journal Article
JOURNALTITLE: Klinicheskaia meditsina.
COUNTRY: USSR
TITLE: [Incidence of pulmonary lesions and the role of pulmonary pathology in mortality among cancer patients]
PUBDATE: 19910701
The majority of cancer patients (95%) whatever the malignancy location are shown to develop various pathological process in the lungs. 20% of lethal outcomes occur due to acute and protracted croup and focal pneumonias. Such pneumonias are often found after the patients death because of a symptomless and atypical course. These findings dictate a necessity of comprehensive pulmonological studies in cancer patients and administration of detoxication therapy to manage the bronchial obstruction syndrome registered in 39% of cancer patients probably as an early stage of further pulmonary impairment.

9. DOCID:19397 SCORE: 0.00322990679908484
DOCNO: 1321398
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Renal Dialysis
QUALIFIER: immunology
QUALIFIER: immunology
AUTHOR: E Ibrányi E
AUTHOR: I Mihály I
AUTHOR: M Kovács M
AUTHOR: L Telegdy L
AFFILIATION: V. sz. Belosztály, Fóvárosi Szent László Kórház, Budapest.
PUBTYPE: Journal Article
JOURNALTITLE: Orvosi hetilap.
COUNTRY: HUNGARY
TITLE: [Delta virus infection in hemodialyzed kidney patients and patients with chronic liver diseases]
PUBDATE: 19920701
Sera of patients with chronic hepatitis and chronic haemodialysed uraemia were tested for both Hepatitis B virus and Hepatitis Delta virus markers from 1985. Hepatitis Delta virus seroconversion was found in 10 of 88 haemodialysed patients and anti-Delta-IgG sero-positivity in 11 of 108 chronic hepatitis patients. The clinical course of Delta superinfections in haemodialysed patients was as follows: 3 infections were symptomless, 7 patients had acute hepatitis, two of the latter group died because of fulminant hepatitis. Of the 11 HBsAg and anti-Delta-IgG positive chronic hepatitis patients 3 had primary hepatocellular cancer.

10. DOCID:16352 SCORE: 0.00304838185960706
DOCNO: 7691051
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
AUTHOR: M Sladden M
AUTHOR: J Dickinson J
AFFILIATION: Department of Health, Housing and Community Services, Canberra.
PUBTYPE: Journal Article
JOURNALTITLE: Australian family physician.
COUNTRY: AUSTRALIA
TITLE: Effectiveness of screening for prostate cancer.
PUBDATE: 19930801
In this, our second article, we assess the value of screening for prostate cancer. There is insufficient evidence to recommend for or against routine digital rectal examination as an effective screening test for prostate cancer in asymptomatic men. It is recommended that tumour markers, such as prostate specific antigen, and transrectal ultrasound are not used for routine screening purposes.

11. DOCID:19800 SCORE: 0.00301413444578713
DOCNO: 1573784
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: physiology
QUALIFIER: physiology
AUTHOR: B A Stoll BA
AFFILIATION: Oncology Department, St. Thomas' Hospital, London, U.K.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Japanese journal of clinical oncology.
COUNTRY: JAPAN
TITLE: Breast cancer risk in Japanese women with special reference to the growth hormone-insulin-like growth factor axis.
PUBDATE: 19920201
Earlier physical maturity in girls, involving an earlier and more marked growth hormone spurt and also an earlier menarche, is a marker of subsequent higher risk to breast cancer. Based on the results of recent research, it is postulated that interaction between growth hormone, insulin-like growth factor and sex steroids at an earlier age, has a major role in stimulating not only linear growth but also precocious proliferative activity in the breasts of adolescent girls. This may promote carcinogenesis in a susceptible mammary epithelium and could partly account for the rising breast cancer mortality rate among both Japanese and Western women.

12. DOCID:18788 SCORE: 0.00300568666697872
DOCNO: 1395858
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Esophagoscopes
QUALIFIER: ultrasonography
QUALIFIER: instrumentation
QUALIFIER: ultrasonography
QUALIFIER: instrumentation
AUTHOR: A Heintz A
AUTHOR: W Wahl W
AUTHOR: P Mildenberger P
AUTHOR: S Braunstein S
AUTHOR: M Georg M
AUTHOR: T Junginger T
AFFILIATION: Klinik und Poliklinik für Allgemein- und Abdominalchirurgie, Johannes-Gutenberg-Universität Mainz.
PUBTYPE: Journal Article
JOURNALTITLE: Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen.
COUNTRY: GERMANY
TITLE: [Endosonography of esophageal cancer. Results of a clinical study and in vitro analysis]
PUBDATE: 19920801
From April 1989 to June 1991 63 patients with esophageal cancer were investigated by endosonography with the object of ascertaining the depth of intrathoracic tumor infiltration and lymphnode involvement. The sensitivity in diagnosing tumor infiltration amount to 0.74; the sensitivity for involvement of regional lymphnode was 0.84, specificity 0.44. In an in-vitro analysis endosonographic criteria for the assessment of regional lymphnodes are proved. Echogenic structure seems not to be a valuable criterium.

13. DOCID:18016 SCORE: 0.00296047987378402
DOCNO: 2390245
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
AUTHOR: B H Burmeister BH
AUTHOR: C S Benjamin CS
AUTHOR: W J Childs WJ
AFFILIATION: Department of Clinical Oncology, Auckland Hospital, New Zealand.
PUBTYPE: Journal Article
JOURNALTITLE: Australian and New Zealand journal of ophthalmology.
COUNTRY: AUSTRALIA
TITLE: The management of metastases to eye and orbit from carcinoma of the breast.
PUBDATE: 19900501
This report describes 11 patients who developed visual symptoms due to choroidal or orbital metastases from carcinoma of the breast. All patients were treated using palliative radiotherapy with regression of metastases in five of six patients (83%) having choroidal involvement and three of five patients (60%) having orbital metastases. There were no complications due to radiotherapy. All these patients had advanced metastatic breast cancer with poor survival following development of orbital or choroidal metastases.

14. DOCID:19768 SCORE: 0.00292133106569985
DOCNO: 7684058
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Role
DESCRIPTOR: Terminal Care
QUALIFIER: methods
QUALIFIER: methods
AUTHOR: D Marcant D
AUTHOR: C H Rapin CH
PUBTYPE: Journal Article
JOURNALTITLE: Journal of pain and symptom management.
COUNTRY: UNITED STATES
TITLE: Role of the physiotherapist in palliative care.
PUBDATE: 19930201
Physiotherapists, whether trained in intensive care or internal medicine, must be attentive to patients at the end of their lives. Palliative-care physiotherapy requires basic training in rehabilitation techniques; the integration of a rehabilitation professional in a caregivers team; a profound communication with the patient, leading to an effective accompaniment and direct response to the patient's needs; and recognition of the patient's functional needs. The involvement of the physiotherapist can extend to the very end of life. In a series of 56 geriatric patients (35 suffering from cancer, 21 from other pathologic conditions) who died at the Center of Continuous Care, 44 (79%) had a treatment of respiratory physiotherapy until their last 24 hr.