0. DOCID:11402 SCORE: 0.00663826665632343
DOCNO: 6834959
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: F Bagatella F
AUTHOR: L Bignardi L
PUBTYPE: Journal Article
JOURNALTITLE: The Laryngoscope.
COUNTRY: UNITED STATES
TITLE: Behavior of cancer at the anterior commissure of the larynx.
PUBDATE: 19830301
The present research is concerned with the behavior of the vestibular cancer with respect to the portion of the anterior commissure of the larynx which the authors have named the "x-space." The research is based on the analysis of semiseriated vertical sections showing cancers of the vestibule in stages T1 and T2 with histological gradings 1 and 2. The specimens show that, at least in the early stages of the neoplastic spread, the fibrous structures of the x-space act as a fairly effective barrier to deep diffusion of the tumor. This fact enables the surgeon to estimate macroscopically the lower borders of the tumor growth on the basis of the superficial spread of the cancer in the zone of the x-space.

1. DOCID:11739 SCORE: 0.00615957664938829
DOCNO: 2992746
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: complications
QUALIFIER: etiology
QUALIFIER: secondary
AUTHOR: B I Carr BI
AUTHOR: R Goodkin R
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Breast cancer with osseous metastasis and herniated lumbar disc. A cautionary tale.
PUBDATE: 19851001
A 39-year-old white woman with breast cancer, metastatic to her skeleton, developed low back and left lower extremity pain and lower extremity weakness. A bone scan evidenced increased radioisotope activity in her lumbar spine and a computed tomography (CT) scan showed a lesion of the L4 vertebra. Because of myelographic findings of a extradural defect at the L4-5 disc space and the possibility of a herniated disc causing the patient's pain and neurologic deficit in her lower extremities, the patient underwent surgery and a large herniated L4-5 disc was removed. As a consequence, the patient experienced relief of the lower extremity pain and return of strength in her lower extremities. She died a considerable time later from refractory hypercalcemia.

2. DOCID:10980 SCORE: 0.00525544630899532
DOCNO: 7044682
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
AUTHOR: J F Cade JF
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
PUBTYPE: Randomized Controlled Trial
JOURNALTITLE: Critical care medicine.
COUNTRY: UNITED STATES
TITLE: High risk of the critically ill for venous thromboembolism.
PUBDATE: 19820701
The incidence of deep venous thrombosis of the legs (DVT) was studied in 119 critically ill patients by 125I-labeled fibrinogen scanning; the efficacy of low-dose heparin prophylaxis was assessed in a randomized, double-blind study. DVT occurred in 29% of control patients and in 13% of patients receiving heparin 5000 U subcutaneously twice daily. DVT was found mainly in men and was associated with circulatory impairment, respiratory failure and recent vascular or cancer surgery. In a comparison study of medical patients, DVT occurred in 10% untreated and 2% treated. In conclusion, the critically ill are at high risk of venous thromboembolism and low-dose prophylaxis is warranted in those who have no hemostatic impairment.

3. DOCID:14475 SCORE: 0.0052201517872044
DOCNO: 2586859
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Health Status Indicators
DESCRIPTOR: Housing
QUALIFIER: chemically induced
QUALIFIER: adverse effects
AUTHOR: S Loken S
AUTHOR: T Loken T
AFFILIATION: Salt Lake City Veterans Administration Medical Center, Utah.
PUBTYPE: Journal Article
JOURNALTITLE: The Nurse practitioner.
COUNTRY: UNITED STATES
TITLE: Radon: detection and treatment.
PUBDATE: 19891101
Within the last few years, natural radon exposure in non-industrial settings, primarily homes, has become a health concern. Research has demonstrated that many homes throughout the United States have radon concentrations much higher than the legal federal limits set for miners. Thousands of unsuspecting people are being exposed to high levels of radiation. It is estimated that up to 15 percent of lung cancers are caused from radon. This is a significant health risk. With basic knowledge of the current information on radon, a primary health care provider can address patients' radon concerns and make appropriate referrals.

4. DOCID:13871 SCORE: 0.00499270028767608
DOCNO: 3549189
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Suture Techniques
QUALIFIER: surgery
QUALIFIER: methods
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: mortality
AUTHOR: R Bittner R
AUTHOR: M Butters M
AUTHOR: R Roscher R
AUTHOR: H G Beger HG
PUBTYPE: Journal Article
JOURNALTITLE: Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen.
COUNTRY: GERMANY, WEST
TITLE: [Esophagojejunostomy--how safe is manual suture today?]
PUBDATE: 19870101
Between 1982 and 1986 a total of 137 patients were gastrectomized for cancer of the stomach. The esophago-jejunal anastomosis was always carried out as an end-to-side anastomosis applying the conventional two layer technique. Only in 1 patient (0.7%) an insufficiency of this anastomosis was observed; 9 reoperations (6.6%) were necessary and 3 patients (2.2%) died in the postoperative course. These results confirm that with a precise, standardised conventional suture technique the esophageal anastomosis can be safely performed today.

5. DOCID:10847 SCORE: 0.00493596331539456
DOCNO: 6805770
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: economics
QUALIFIER: psychology
AUTHOR: P Maguire P
AUTHOR: A Pentol A
AUTHOR: D Allen D
AUTHOR: A Tait A
AUTHOR: M Brooke M
AUTHOR: R Sellwood R
PUBTYPE: Journal Article
JOURNALTITLE: British medical journal (Clinical research ed.)
COUNTRY: ENGLAND
TITLE: Cost of counselling women who undergo mastectomy.
PUBDATE: 19820601
The psychiatric morbidity associated with mastectomy and brest cancer was substantially reduced by a specialist nurse who counselled women before and after surgery and monitored their progress. A controlled study was, therefore, carried out to determine what this cost. National Health Service costs were almost wholly covered by savings made because counselled subjects who developed psychiatric problems were recognised and treated much earlier than control patients. Counselled and control subjects suffered considerable financial losses, but these were offset in the counselled group by their relatives' earlier return to work. Such counselling schemes are necessary and effective and may be implemented at little extra cost.

6. DOCID:10646 SCORE: 0.00463843588568093
DOCNO: 6754212
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: therapeutic use
QUALIFIER: therapeutic use
QUALIFIER: prevention & control
QUALIFIER: adverse effects
QUALIFIER: prevention & control
AUTHOR: H H Lucraft HH
AUTHOR: M K Palmer MK
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
PUBTYPE: Randomized Controlled Trial
JOURNALTITLE: Clinical radiology.
COUNTRY: ENGLAND
TITLE: Randomised clinical trial of levonantradol and chlorpromazine in the prevention of radiotherapy-induced vomiting.
PUBDATE: 19821101
Levonantradol is a cannabis derivative. Cannabinoid anti-emetics are being assessed in cancer chemotherapy but have been little used in radiotherapy to date. A pilot study and randomised trial compared the anti-emetic effect of a standard drug (Chlorpromazine 26 mg) with Levonantradol at two doses (0.5 and 0.75 mg) in patients receiving palliative single fraction radiotherapy to sites likely to cause nausea and vomiting. Most patients were out-patients. Both drugs were well tolerated. The frequency of vomiting was similar in all three groups in both the pilot study and randomised trial.

7. DOCID:11684 SCORE: 0.00437612617714974
DOCNO: 6203754
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analysis
QUALIFIER: analysis
QUALIFIER: analysis
AUTHOR: R Wachner R
AUTHOR: C Wittekind C
AUTHOR: S von Kleist S
PUBTYPE: Journal Article
JOURNALTITLE: European journal of cancer & clinical oncology.
COUNTRY: ENGLAND
TITLE: Immunohistological localization of beta-HCG in breast carcinomas.
PUBDATE: 19840501
As reports about HCG positivity in serum or tissue of patients with breast cancer show divergent results, the present investigation was undertaken to study the frequency of positive staining for beta-HCG in breast cancer tissue and to correlate the staining pattern with the histology of the tumor and stage of disease. With the immunoperoxidase technique we studied 129 cases of breast carcinomas. We obtained a positive staining for beta-HCG in 12%. However, in most of the tumors only very few cells contained beta-HCG. Morphologically the positive cells could not be distinguished from beta-HCG-negative cells. We conclude from our data that until now the beta-HCG staining provides no immediate useful information for the management of patients.

8. DOCID:15583 SCORE: 0.0043265144637482
DOCNO: 2801597
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: R F Asbury RF
AUTHOR: J A Blessing JA
AUTHOR: P J DiSaia PJ
AUTHOR: J Malfetano J
AFFILIATION: Department of Medicine in Oncology, University of Rochester School of Medicine, New York.
PUBTYPE: Journal Article
JOURNALTITLE: American journal of clinical oncology : the official publication of the American Radium Society.
COUNTRY: UNITED STATES
TITLE: Aminothiadiazole (NSC 4728) in patients with advanced nonsquamous carcinoma of the cervix. A phase II study of the Gynecologic Oncology Group.
PUBDATE: 19891001
Twenty-six evaluable patients with advanced nonsquamous cell cervical cancer were treated with aminothiadiazole at a dosage of 125 mg/m2 weekly. Sixteen had received prior chemotherapy. Two patients had complete responses neither had received prior chemotherapy; nine had stable disease; 15 had increasing disease. There was a single life-threatening toxic episode. Aminothiadiazole used in this dosage and schedule has minimal activity in previously treated patients with nonsquamous cell carcinoma.

9. DOCID:10048 SCORE: 0.00432540724582389
DOCNO: 6722009
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
QUALIFIER: therapeutic use
AUTHOR: A Nethersell A
AUTHOR: H Smedley H
AUTHOR: M Katrak M
AUTHOR: T Wheeler T
AUTHOR: K Sikora K
PUBTYPE: Journal Article
JOURNALTITLE: British journal of cancer.
COUNTRY: ENGLAND
TITLE: Recombinant interferon in advanced breast cancer.
PUBDATE: 19840501
Fifteen patients with locally advanced refractory breast cancer have been treated with recombinant leucocyte interferon ( rIFN -alpha A) for up to 12 weeks. Toxicity was considerable with the initial dosage schedule employed but became acceptable after reducing the starting dose by 50%. Minor side effects occurred in all patients and major CNS toxicity in six. Nine patients showed some evidence of tumour regression at 4 weeks. Only two of these were still responding at 12 weeks. Response was unrelated to the length of previous history, oestrogen receptor status or previous responsiveness to cytotoxic or hormone therapy.

10. DOCID:13421 SCORE: 0.00428247125535613
DOCNO: 2618184
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: genetics
QUALIFIER: genetics
AUTHOR: H Wich H
AUTHOR: G Franke G
AUTHOR: U Grimm U
AUTHOR: W Siegmund W
AFFILIATION: Urologische Klinik, Bezirkskrankenhauses Heinrich Braun Zwickau.
PUBTYPE: Journal Article
JOURNALTITLE: Zeitschrift für Urologie und Nephrologie.
COUNTRY: GERMANY, EAST
TITLE: [The acetylator phenotype in patients with urinary bladder cancer]
PUBDATE: 19891101
In 53 patients suffering from bladder cancer the acelylization phenotype was examined. The frequency of slow acetylizers (70%) was significantly higher than in the control group. The more frequently occurrence of slow acetylizers in the group with professional pollutant exposition is an important reference to a higher bladder cancer morbidity in the case of carcinogen contact. A screening of the acetylization phenotype in professions with carcinogen contact may be important in the prophylaxis of bladder cancer.

11. DOCID:11888 SCORE: 0.00421564394721443
DOCNO: 6513026
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: K Matsumoto K
AUTHOR: Y Sugiyama Y
AUTHOR: K Miyagishima K
AUTHOR: T Murakami T
AUTHOR: N Yamagata N
AUTHOR: H Tsuchida H
AUTHOR: M Sasamura M
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [Primary adenosquamous carcinoma of the stomach--a case report]
PUBDATE: 19841001
A 56-year-old man was hospitalized with the complaint of upper abdominal discomfort. A gastrointestinal series revealed a filling defect in the body of the stomach. Under the diagnosis of gastric cancer, total gastrectomy was performed. Borrmann III type cancer measuring 5 X 4 cm, extending to the antrum and the upper portion of the body of the stomach, was identified in the body. Histologically, most of the tumor consisted of squamous cell carcinoma. Adenocarcinoma and a small nest of squamous metaplasia were observed at the peripheral wall of this tumor. The pathological diagnosis was adenosquamous carcinoma. In some regional lymph nodes, metastasis of adenocarcinoma was observed.

12. DOCID:14424 SCORE: 0.00420201818132751
DOCNO: 2573995
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: administration & dosage
QUALIFIER: physiopathology
QUALIFIER: therapy
AUTHOR: E T Creagan ET
AUTHOR: J M Wilkinson JM
AFFILIATION: Mayo Medical School, Rochester, Minnesota.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: American family physician.
COUNTRY: UNITED STATES
TITLE: Pain relief in terminally ill patients.
PUBDATE: 19891201
A systematic approach to identifying the cause of pain and rational use of drug therapy are keys to providing pain relief to cancer patients. Aspirin, acetaminophen and nonsteroidal anti-inflammatory drugs are effective for mild to moderate pain, and they enhance the effectiveness of weak oral narcotics, such as codeine. For severe pain, morphine is the drug of choice. A variety of adjuvant drugs can be used to enhance the effect of narcotics and to treat specific side effects of the disease or of therapy. For the terminally ill patient, a peaceful death with dignity should always be possible.

13. DOCID:14781 SCORE: 0.0041806250461546
DOCNO: 3345533
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: complications
QUALIFIER: etiology
AUTHOR: K Fukuda K
AUTHOR: A Shibata A
AFFILIATION: Department of Public Health, Kurume University School of Medicine, Japan.
PUBTYPE: Journal Article
JOURNALTITLE: Cancer research.
COUNTRY: UNITED STATES
TITLE: A case-control study of past history of nasal diseases and maxillary sinus cancer in Hokkaido, Japan.
PUBDATE: 19880301
A case-control study of maxillary sinus cancer was performed in Hokkaido with 116 cases and 232 controls matched for sex, age (within 5 years), and residence (same health center region). Preliminary univariate analyses showed that a history of chronic sinusitis [relative risk (RR) = 3.1]; nasal polyps (RR = 5.7); an occupational history of being a carpenter, joiner, furniture maker, or other woodworker (RR = 2.9); and a history of current or past cigarette smoking (RR = 3.3) were statistically significant risk factors for men. No single item was a significant risk factor for women.

14. DOCID:15369 SCORE: 0.00409133190356646
DOCNO: 3807722
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: administration & dosage
QUALIFIER: administration & dosage
QUALIFIER: radiotherapy
AUTHOR: G M Zharinov GM
AUTHOR: V V Kholin VV
AUTHOR: K P Khanson KP
AUTHOR: A A Val'kovich AA
AUTHOR: V A Volchkov VA
PUBTYPE: Journal Article
JOURNALTITLE: Meditsinskaia radiologiia.
COUNTRY: USSR
TITLE: [Local use of metronidazole in dimethyl sulfoxide in the radiation therapy of cervical cancer]
PUBDATE: 19870201
A method of the local use of metronidazole dissolved in dimethylsulfoxide (DMSO) for cervix uteri cancer patients was worked out. Applications of 1-2 g of metronidazole were well tolerated by the patients. Metronidazole concentrations in cervical tumors were high (about 1000 micrograms/g), in the blood they did not exceed 16 micrograms/ml. Experiments showed that metronidazole in DMSO diffused in the tissue, its concentrations at a distance of 2-3 cm from the surface were 180-260 micrograms/g. The local use of metronidazole in DMSO caused an increase in the rate of tumor radiation regression.