0. DOCID:27836 SCORE: 0.00378585096165498
DOCNO: 10803401
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Peritoneovenous Shunt
QUALIFIER: diagnosis
QUALIFIER: therapy
AUTHOR: M Roskos M
AUTHOR: M B Popp MB
AFFILIATION: Department of Surgery, The Jewish Hospital, Cincinnati, Ohio, USA.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Surgical laparoscopy, endoscopy & percutaneous techniques.
COUNTRY: UNITED STATES
TITLE: Laparoscopic diagnosis and management of malignant ascites.
PUBDATE: 19991001
Malignancy is the second most common cause of ascites. Tissue diagnosis is often difficult because the cytology of ascitic fluid is positive in only 57% of cases. Peritoneovenous shunting is often used as palliation in such patients and has proven superior to nonoperative management for some patients. We present three cases of malignant ascites with negative cytologies managed by using laparoscopic biopsies to confirm intraperitoneal cancer and assist in the placement of a peritoneovenous shunt. Results suggest that exploratory laparoscopy and shunt placement is a valuable procedure in these patients with a limited life expectancy and is preferable to open laparotomy.


1. DOCID:31507 SCORE: 0.00335905761712167
DOCNO: 15776005
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Immune Tolerance
DESCRIPTOR: Tumor Escape
QUALIFIER: immunology
AUTHOR: Weiping Zou W
AFFILIATION: Tulane University Health Sciences Center, Section of Hematology and Medical Oncology, 1430 Tulane Avenue, New Orleans, Louisiana 70112-2699, USA. wzou@tulane.edu
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Nature reviews. Cancer.
COUNTRY: England
TITLE: Immunosuppressive networks in the tumour environment and their therapeutic relevance.
PUBDATE: 20050401
It is well known that many tumours are potentially immunogenic, as corroborated by the presence of tumour-specific immune responses in vivo. Nonetheless, spontaneous clearance of established tumours by endogenous immune mechanisms is rare. Therefore, the focus of most cancer immunotherapies is to supplement essential immunogenic elements to boost tumour-specific immunity. Why then has tumour immunotherapy resulted in a generally poor clinical efficiency? The reason might lie in the increasingly documented fact that tumours develop diverse strategies that escape tumour-specific immunity.


2. DOCID:25902 SCORE: 0.00313531098968199
DOCNO: 10642079
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Nutritional Support
QUALIFIER: metabolism
AUTHOR: A M Cooperman AM
AUTHOR: J Chivati J
AUTHOR: R S Chamberlain RS
AFFILIATION: Institute for Liver, Biliary and Pancreatic Surgery, Community Hospital of Dobbs Ferry, New York 10522, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Current opinion in clinical nutrition and metabolic care.
COUNTRY: ENGLAND
TITLE: Nutritional and metabolic aspects of pancreatic cancer.
PUBDATE: 20000101
Most patients with pancreatic cancer suffer from a variety of severe metabolic and nutritional disturbances. Despite this fact, the role of perioperative nutritional support for these patients remains controversial. This review highlights the results of randomized prospective clinical trials, and meta-analyses that have addressed this issue. The 'current opinion' put forth in this discussion is based on these reviews, and on personal observations in treating more than 500 patients.


3. DOCID:31377 SCORE: 0.00313100106558988
DOCNO: 15770817
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: etiology
QUALIFIER: drug therapy
AUTHOR: A Zouhair A
AUTHOR: P H Wiesel PH
AFFILIATION: Service de radio-oncologie, CHUV, 1011 Lausanne.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Revue médicale suisse.
COUNTRY: Switzerland
TITLE: [Non-surgical treatment of acute and late radiation proctitis]
PUBDATE: 20050101
Pelvic external radiotherapy with or without brachytherapy plays an important role in the management of pelvic cancers. Despite recent technical innovations including conformal three-dimensional (3D) external beam radiotherapy and more recently intensity modulated radiotherapy (IMRT), local side effects can occur secondary to normal tissue damage caused by ionising radiation. Morbidity depends on the anatomic position of the rectum within the pelvis and the fast turnover rate of the mucosa, as well as the characteristics of the radiation treatment and patient co-morbidities. Medical management is sometimes complex and merits herein a short review.


4. DOCID:27007 SCORE: 0.00291394736831368
DOCNO: 11783101
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: C Wang C
AUTHOR: T Ding T
AUTHOR: L Chang L
AFFILIATION: Shanxi Tumor Hospital, Taiyuan 030013, China.
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
PUBTYPE: Randomized Controlled Trial
JOURNALTITLE: Zhonghua zhong liu za zhi [Chinese journal of oncology].
COUNTRY: China
TITLE: [A randomized clinical study of preoperative chemotherapy for esophageal carcinoma]
PUBDATE: 20010501
OBJECTIVE: To evaluate the effect of preoperative chemotherapy on the prognosis of stage II or III patients with esophageal carcinoma. METHODS: From February 1991 to June 1994, 50 patients with stage II, III esophageal carcinoma were treated with preoperative combination (CDDP) chemotherapy and compared with 50 patients received operation alone. RESULTS: The 5-year survival rate of the operation group and preoperative chemotherapy group was 32% and 46%, respectively. The difference was statistically significant. CONCLUSION: Preoperative chemotherapy improves survival of surgically treated esophageal cancer patients.


5. DOCID:27769 SCORE: 0.00290612499120429
DOCNO: 11747925
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Accidents, Radiation
DESCRIPTOR: Nuclear Reactors
QUALIFIER: epidemiology
QUALIFIER: epidemiology
AUTHOR: Y Shibata Y
AUTHOR: S Yamashita S
AUTHOR: V B Masyakin VB
AUTHOR: G D Panasyuk GD
AUTHOR: S Nagataki S
PUBTYPE: Letter
JOURNALTITLE: Lancet.
COUNTRY: England
TITLE: 15 years after Chernobyl: new evidence of thyroid cancer.
PUBDATE: 20011201
The Chernobyl nuclear power plant accident happened on April 26, 1986. We investigated the cause of the striking increase in frequency of thyroid cancer in children who lived within a 150 km radius of Chernobyl and who were born before and after the accident. No thyroid cancer was seen in 9472 children born in 1987-89, whereas one and 31 thyroid cancers were recorded in 2409 children born April 27, 1986, to Dec 31, 1986, and 9720 born Jan 1, 1983, to April 26, 1986, respectively. Short-lived radioactive fallout caused by the Chernobyl accident probably induced thyroid cancer in children living near Chernobyl.


6. DOCID:31864 SCORE: 0.00283835906369146
DOCNO: 16224168
OWNER: NLM
STATUS: In-Process
AUTHOR: Sung Ho Song SH
AUTHOR: Ick Jang I
AUTHOR: Bum Sik Kim BS
AUTHOR: Eun Tak Kim ET
AUTHOR: Seung-Hyo Woo SH
AUTHOR: Mee Ja Park MJ
AUTHOR: Chang Nam Kim CN
AFFILIATION: Department of Urology, Eulji Medical University, Daejeon, Korea.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Journal of Korean medical science.
COUNTRY: Korea (South)
TITLE: A case of primary syphilis in the rectum.
PUBDATE: 20051001
A 30-yr-old man was referred for suspicious rectal cancer because of ulcerated lesions in the rectum and a palpable mass in left inguinal area. Sigmoidoscopy showed two indurated masses and histologic evaluation of biopsy revealed obliterative endarteritis with heavy plasma cell infiltration. Both venereal disease research laboratories (VDRL) and fluorescent treponemal antibody absorption (FTA-ABS) tests were positive. After injection of penicillin G benzathine for 3 weeks, the rectal chancre and the palpable mass disappeared.


7. DOCID:25104 SCORE: 0.00283553852944359
DOCNO: 11905809
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Pharmacogenetics
QUALIFIER: drug therapy
AUTHOR: M V Relling MV
AUTHOR: T Dervieux T
AFFILIATION: Department of Pharmaceutical Sciences, St Jude Children's Research Hospital, Memphis, Tennessee 38105, USA. mary.relling@stjude.org
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Nature reviews. Cancer.
COUNTRY: England
TITLE: Pharmacogenetics and cancer therapy.
PUBDATE: 20011101
Pharmacogenetics is the study of how genetic variations affect drug response. These variations can affect a patient's response to cancer drugs, for which there is usually a fine line between a dosage that has a therapeutic effect and one that produces toxicity. Gaining better insight into the genetic elements of both the patient and the tumour that affect drug efficacy will eventually allow for individualized dosage determination and fewer adverse effects.


8. DOCID:31514 SCORE: 0.00276781669502462
DOCNO: 15517115
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: methods
AUTHOR: J Weitz J
AUTHOR: M Koch M
AUTHOR: J Kleeff J
AUTHOR: M W Müller MW
AUTHOR: J Schmidt J
AUTHOR: H Friess H
AUTHOR: M W Büchler MW
AFFILIATION: Abteilung für Allgemein-, Visceral- und Unfallchirurgie, Chirurgische Universitätsklinik Heidelberg.
PUBTYPE: Journal Article
JOURNALTITLE: Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen.
COUNTRY: Germany
TITLE: [Kausch-Whipple pancreaticoduodenectomy. Technique and results]
PUBDATE: 20041101
The Kausch-Whipple operation is the standard procedure for resection of pancreatic head cancer, distal bile duct cancer, and periampullary cancers. It is also used for some cases of chronic pancreatitis. Traditionally, this operation is associated with high perioperative morbidity and mortality. The aim of our study was to present our current technique for Kausch-Whipple pancreaticoduodenectomy and to demonstrate that acceptable perioperative and long-term outcomes can be achieved by a standardised technique in a high-volume centre.


9. DOCID:30735 SCORE: 0.00275815881213456
DOCNO: 15013720
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Depsipeptides
QUALIFIER: analogs & derivatives
QUALIFIER: drug effects
QUALIFIER: drug effects
QUALIFIER: methods
QUALIFIER: drug therapy
QUALIFIER: genetics
AUTHOR: David S Schrump DS
AFFILIATION: Thoracic Oncology Section, Surgery Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892, USA. david_Schrump@nih.gov
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The Journal of surgical research.
COUNTRY: United States
TITLE: Genomic surgery for lung cancer.
PUBDATE: 20040301
An emerging body of literature indicates that reversible alterations in chromatin structure modulate gene expression during malignant transformation. Chromatin structure is regulated in part by DNA methylation and histone acetylation; these independent yet highly interrelated epigenetic processes are influenced by a variety of signal transduction pathways. The present review highlights recent advances regarding cancer epigenetics, focusing on the potential utilization of chromatin remodeling agents to induce apoptosis and enhance the immunogenicity of thoracic malignancies.


10. DOCID:26956 SCORE: 0.00269986125629222
DOCNO: 10410154
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Protein Biosynthesis
QUALIFIER: complications
QUALIFIER: therapeutic use
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: etiology
QUALIFIER: complications
AUTHOR: H Koshida H
AUTHOR: T Kametani T
AUTHOR: S Masuda S
AFFILIATION: Second Dept. of Internal Medicine, Kohseiren Takaoka Hospital.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [A case of lung cancer with hypercalcemia and renal failure responsive to pamidronate]
PUBDATE: 19990501
A 46-year-old man was diagnosed as Stage IV lung cancer with neck lymph node and bilateral adrenal metastases. He was treated with seven courses of combined chemotherapy (CDDP + etoposide), until he showed extreme hypercalcemia and acute renal failure. The bisphosphonate, pamidronate with elcatonin and prednisolone dramatically lowered his serum calcium level and normalized his renal function. This is a representative case of humoral hypercalcemia of malignancy whose serum calcium could be safely and effectively controlled with pamidronate.


11. DOCID:30484 SCORE: 0.00264522668878192
DOCNO: 16139035
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: therapy
AUTHOR: Ricardo J Gonzalez RJ
AUTHOR: Paul F Mansfield PF
AFFILIATION: Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Unit 444, 1515 Holcombe Boulevard, Houston, TX 77030-5235, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The Surgical clinics of North America.
COUNTRY: United States
TITLE: Adjuvant and neoadjuvant therapy for gastric cancer.
PUBDATE: 20051001
Although the incidence of gastric cancer is decreasing, it remains a significant source of cancer-related mortality. Surgery remains the best chance for cure from gastric cancer. Adjuvant and neoadjuvant therapy have played increasing roles in attempting to reduce the disease-specific mortality and prolong survival. In this article, the authors review the literature and summarize the salient points regarding the roles of adjuvant and neoadjuvant therapy for gastric cancer.


12. DOCID:27813 SCORE: 0.00258343586518378
DOCNO: 10717232
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Apoptosis
QUALIFIER: physiology
QUALIFIER: physiology
QUALIFIER: physiology
AUTHOR: Y R Chen YR
AUTHOR: T H Tan TH
AFFILIATION: Department of Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: International journal of oncology.
COUNTRY: GREECE
TITLE: The c-Jun N-terminal kinase pathway and apoptotic signaling (review).
PUBDATE: 20000401
The c-Jun N-terminal kinase (JNK) group of mitogen-activated protein kinases (MAPKs) is activated in mammalian cells by environmental stress, pro-inflammatory cytokines, and mitogenic stimuli. Biochemical and genetic studies demonstrate that JNK regulates the activities of many transcription factors, and that the JNK pathway is required for the regulation of inflammatory responses, cell proliferation, and apoptosis. The involvement of JNK in apoptotic cell death is particularly intriguing, and has been actively studied in recent years. An improved understanding of JNK-mediated apoptotic signaling may provide novel strategies in prevention and treatment of cancers.


13. DOCID:24834 SCORE: 0.00256862339976493
DOCNO: 12541408
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
AUTHOR: N K Zhang NK
AUTHOR: T X Shi TX
AUTHOR: Y C Liu YC
AFFILIATION: Department of Otolaryngology, Affiliated Hospital of Qingdao University, Medical College, Qingdao 266003.
PUBTYPE: Journal Article
JOURNALTITLE: Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology.
COUNTRY: China
TITLE: [16 cases of laryngeal keratosis treated with viaminati]
PUBDATE: 20000301
OBJECTIVE: To investigate the treatment efficient of viaminati on the laryngeal keratosis. METHOD: All 16 cases of laryngeal keratosis took viaminati. RESULT: 15 cases were recovered. 1 case was developed cancer. CONCLUSION: Viaminati is effective in treating laryngeal keratosis and has not obvious side-effect.


14. DOCID:31802 SCORE: 0.00256576676034488
DOCNO: 12768868
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Mammaplasty
DESCRIPTOR: Surgical Flaps
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: methods
AUTHOR: E Vandeweyer E
AFFILIATION: Plastic and Reconstructive Surgery Department, Clinique L. Cathy, Rue Louis Cathy, 136, 7331 Baudour. vandeweyere@skynet.be
PUBTYPE: Journal Article
JOURNALTITLE: Acta chirurgica Belgica.
COUNTRY: Belgium
TITLE: Peri-areolar skin-sparing mastectomy and immediate tram flap reconstruction.
PUBDATE: 20030401
The association of peri-areolar skin-sparing mastectomy with immediate autologous tissue breast reconstruction could be proposed to selected patients necessitating mastectomy to control their breast cancer. A prospective series of 14 consecutive patients were operated using this association and evaluated. Mean age at time of surgery was 52 years. Mean operating time for reconstruction was 163 minutes. There were two minor local complications, one needing secondary adaptation under local anaesthesia. Cosmetic result was judged good to excellent by all the patients with a mean follow-up of 13.2 months.