0. DOCID:23013 SCORE: 0.00323721237890395
DOCNO: 7853158
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Ankle Joint
QUALIFIER: diagnosis
QUALIFIER: diagnosis
QUALIFIER: pathology
AUTHOR: E E Leonheart EE
AUTHOR: J DiStazio J
AFFILIATION: Podiatry Hospital, Pittsburgh, PA.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Journal of the American Podiatric Medical Association.
COUNTRY: UNITED STATES
TITLE: Acrometastases. Initial presentation as diffuse ankle pain.
PUBDATE: 19941201
Acrometastases are rare and often misdiagnosed or overlooked. When it involves the feet, it generally attacks the larger bones containing the higher amounts of red marrow. The patient may or may not have a known history of cancer, which makes diagnosis much more difficult. The symptomatology is generally vague and can mimic other conditions, such as osteomyelitis, gouty rheumatoid arthritis, Reiter's syndrome, Paget's disease, osteochondral lesions, and ligamentous sprains. Therefore, the physician must consider metastatic disease in the differential diagnosis. Once the diagnosis is made, the prognosis is poor and treatment is limited to pain relief and maintaining function.


1. DOCID:23288 SCORE: 0.00313177884316027
DOCNO: 8028292
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: ultrasonography
AUTHOR: T A Kirkland TA
AUTHOR: J E Lathem JE
AFFILIATION: Department of Urology, Medical University of South Carolina, Charleston 29425.
PUBTYPE: Journal Article
JOURNALTITLE: Journal of the South Carolina Medical Association (1975)
COUNTRY: UNITED STATES
TITLE: The role of transrectal ultrasound (TRUS) in the evaluation of cancer of the prostate.
PUBDATE: 19940501
While TRUS is not of value as a screening tool, it is of considerable value in the early detection of cancer of the prostate in men with abnormal DRE and/or PSA. TRUS enables calculation of PSA density to identify men at low risk, thus eliminating many unnecessary biopsies. This results in favorable impact on both cost and morbidity. When biopsy is necessary, TRUS greatly enhances accuracy. Its role in staging is of less importance but can be useful when positive, and it adds little to the cost or complexity of the examination.


2. DOCID:19009 SCORE: 0.00308829815111136
DOCNO: 8405372
AUTHOR: J Knowland J
AUTHOR: E A McKenzie EA
AUTHOR: P J McHugh PJ
AUTHOR: N A Cridland NA
AFFILIATION: Department of Biochemistry, South Parks Road, Oxford OX1 3QU, UK.
PUBTYPE: Journal Article
JOURNALTITLE: FEBS letters.
COUNTRY: NETHERLANDS
TITLE: Sunlight-induced mutagenicity of a common sunscreen ingredient.
PUBDATE: 19930601
We have tested the mutagenicity of a UV-B sunscreen ingredient called Padimate-O or octyl dimethyl PABA, which, chemically speaking, is identical to an industrial chemical that generates free radicals when illuminated. It is harmless in the dark but mutagenic in sunlight, attacking DNA directly. A commercial sunscreen containing Padimate-O behaves in the same way. UV-A in sunlight also excites Padimate-O, although less than UV-B. Some related compounds, including a known carcinogen, behave similarly. As mutagens may be carcinogenic, our results suggest that some sunscreens could, while preventing sunburn, contribute to sunlight-related cancers.


3. DOCID:16731 SCORE: 0.00297523861186542
DOCNO: 1967109
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
QUALIFIER: administration & dosage
QUALIFIER: administration & dosage
QUALIFIER: methods
QUALIFIER: administration & dosage
QUALIFIER: therapy
AUTHOR: J Brahm J
AUTHOR: J Chesta J
AUTHOR: V Gaínza V
AUTHOR: V Arriagada V
AFFILIATION: Centro de Gastroenterología, Universidad de Chile, Santiago.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Revista médica de Chile.
COUNTRY: CHILE
TITLE: [Selective chemoembolization with adriamycin-Urografin-Lipiodol in the treatment of hepatocarcinoma]
PUBDATE: 19901001
Various methods of regional chemotherapy have been used in patients with non resectable heptic carcinoma. We report our preliminary experience with embolization using adriamycin-urographin-lipiodol in 2 patients with this cancer in whom a considerable reduction of tumoral mass was observed. The pertinent literature is briefly commented.


4. DOCID:19326 SCORE: 0.0028004105711638
DOCNO: 1894956
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: W Lange W
AUTHOR: W Brugger W
AUTHOR: F M Rosenthal FM
AUTHOR: L Kanz L
AUTHOR: A Lindemann A
AFFILIATION: Albert-Ludwigs University Medical Center, Department of Hematology and Oncology, Freiburg, Germany.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: International journal of cell cloning.
COUNTRY: UNITED STATES
TITLE: The role of cytokines in oncology.
PUBDATE: 19910701
The availability of sufficient quantities of recombinant human cytokines and promising preclinical data have led to their introduction into clinical trials. Cytokines have potential as new therapeutic agents in a variety of hematological disorders as well as in solid tumors. Only a few of the still increasing number of these glycoprotein hormones have been studied in humans so far, either as single agents or in combination with chemotherapy and other cytokines. Their clinical effects, beneficial role in supportive care, and use in the treatment of certain cancer patients are reviewed.


5. DOCID:18178 SCORE: 0.00272973494382464
DOCNO: 7681998
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Palliative Care
DESCRIPTOR: Radiotherapy, High-Energy
QUALIFIER: complications
QUALIFIER: radiation effects
QUALIFIER: etiology
QUALIFIER: radiotherapy
QUALIFIER: complications
AUTHOR: E G Russi EG
AUTHOR: S Pergolizzi S
AUTHOR: M Gaeta M
AUTHOR: M Mesiti M
AUTHOR: A D'Aquino A
AUTHOR: P Delia P
AFFILIATION: Department of Biomedical Technology (Radiobiomedical Research), IST, Genova, Italy.
PUBTYPE: Journal Article
JOURNALTITLE: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.
COUNTRY: IRELAND
TITLE: Palliative-radiotherapy in lumbosacral carcinomatous neuropathy.
PUBDATE: 19930201
The authors report their own experience in obtaining pain relief in 13 recurrent or disseminated cancer patients affected by lumbosacral carcinomatous neuropathy (LCN). The site, where the disease involved the lumbosacral plexus or its branches, was palliatively irradiated with a few large fractions. The average duration of response was 196 days. Median survival (uncensored) was 185 days (range 47-636 days).


6. DOCID:19208 SCORE: 0.00268309570465666
DOCNO: 10171339
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: economics
QUALIFIER: economics
QUALIFIER: economics
AUTHOR: H D Banta HD
AFFILIATION: The Netherlands Organization for Applied Scientific Research (TNO), Leiden.
PUBTYPE: Journal Article
JOURNALTITLE: Health policy (Amsterdam, Netherlands)
COUNTRY: NETHERLANDS
TITLE: The cost-effectiveness of 10 selected applications in minimally invasive therapy.
PUBDATE: 19930101
In this article, evidence of effectiveness and cost-effectiveness of the following procedures is reviewed: (1) laser treatment of bladder tumors; (2) extracorporeal shock-wave lithotripsy and percutaneous nephrolithotomy; (3) laparoscopic treatment of endometriosis; (4) laparoscopic removal of ovarian cysts; (5) laparoscopic cholecystectomy; (6) laparoscopic appendectomy; (7) catheter treatment of coronary artery disease; (8) palliation of colon cancer by endoscopic intervention; (9) treatment of upper gastrointestinal (UGI) bleeding by endoscopic intervention; and (10) arthroscopic knee surgery. Despite considerable potential to be effective and cost-effective, evidence is disappointingly limited in these cases. The lack of evidence hampers decision-making in this new field.


7. DOCID:23268 SCORE: 0.002660380669859
DOCNO: 7544559
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
AUTHOR: J J Tjandra JJ
AFFILIATION: Private Medical Centre, Royal Melbourne Hospital, Parkville, Victoria, Australia.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Annals of the Academy of Medicine, Singapore.
COUNTRY: SINGAPORE
TITLE: Surgical management of the locally advanced pelvic malignancy--the colorectal surgeon's view.
PUBDATE: 19950301
About 10% of patients with newly diagnosed colorectal cancer will have locally advanced disease without gross evidence of distant or discontiguous intraabdominal metastases. Long-term cure or disease-free survival frequently follows extended resection for a locally advanced primary colorectal carcinoma. The use of adjuvant combined chemo-radiation therapy is still being evaluated. While complete resection of recurrent disease sometimes provides the best long-term survival when compared with other treatment modalities, few patients are suitable candidates for curative resection. In our experience, major extended resection for recurrent pelvic disease is largely palliative and is rarely associated with long-term survival.


8. DOCID:21570 SCORE: 0.00264260035149166
DOCNO: 7774834
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: methods
QUALIFIER: methods
QUALIFIER: surgery
AUTHOR: A J McCartney AJ
AUTHOR: N Johnson N
AFFILIATION: Western Australian State Gynaecologic Oncology Service, King Edward Memorial Hospital for Women, Subiaco, Perth, Western Australia.
PUBTYPE: Journal Article
JOURNALTITLE: Gynecologic oncology.
COUNTRY: UNITED STATES
TITLE: Using a vaginal tube to exteriorize lymph nodes during a laparoscopic pelvic lymphadenectomy.
PUBDATE: 19950601
Laparoscopic pelvic lymphadenectomy for gynecological malignancy involves mobilizing and exteriorizing the lymph nodes. We removed the nodes by passing a 4- to 5-cm-diameter tube through the vagina to the abdomen following the hysterectomy. The nodes were passed through the tube rather than pulled through the abdominal ports. The tube is easy to insert and is a valuable conduit for exteriorizing tissue during laparoscopic pelvic surgery for gynecological cancer.


9. DOCID:18836 SCORE: 0.00259436225248058
DOCNO: 2341731
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: drug therapy
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
QUALIFIER: therapeutic use
AUTHOR: S Gururangan S
AUTHOR: R F Stevens RF
AUTHOR: D J Morris DJ
AFFILIATION: Department of Paediatric Oncology, Royal Manchester Children's Hospital, U.K.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of infection.
COUNTRY: ENGLAND
TITLE: Ribavirin response in measles pneumonia.
PUBDATE: 19900501
A 9-year-old boy with Hodgkin's disease developed measles 1 month after completing eight courses of intensive anti-cancer chemotherapy. The atypical nature of the rash and the absence of Koplik's spots indicated a high risk of progression to fatal giant cell pneumonia. Seven days nebulised and intravenous ribavirin therapy produced apparent recovery. Two weeks later the child presented with measles giant cell pneumonia diagnosed on open lung biopsy. Ribavirin therapy was again successful. The role of ribavirin in the treatment of measles in immunocompromised children is discussed.


10. DOCID:18509 SCORE: 0.00258165415765031
DOCNO: 1651685
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: analogs & derivatives
QUALIFIER: antagonists & inhibitors
QUALIFIER: drug therapy
QUALIFIER: drug therapy
AUTHOR: T Taguchi T
AFFILIATION: Hospital Attached to Research Institute for Microbial Diseases, Osaka University, Japan.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [DNA topoisomerase inhibitor as chemotherapeutic drug--clinical point of view]
PUBDATE: 19910801
CPT-11 is a semisynthesized derivative of camptothecin that has a potent antitumor activity by inhibiting DNA topoisomerase I. Leukopenia (mainly neutropenia) is DLF (dose limiting factor) and MTD (maximum tolerated dose) is higher than 250 mg/m2 in CPT-11 from the results of clinical phase I study. Now we are going on phase II study of CPT-11. We are seeing the cases responded to the drug in cancer of the lung, ovary, uterus, stomach, colorectum, pancreas, breast, malignant lymphoma etc.


11. DOCID:19710 SCORE: 0.00254376201228927
DOCNO: 1671606
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Taxoids
QUALIFIER: pharmacology
AUTHOR: I Ringel I
AUTHOR: S B Horwitz SB
AFFILIATION: Department of Pharmacology, Hadassah Medical School, Hebrew University, Jerusalem, Israel.
PUBTYPE: Journal Article
JOURNALTITLE: Journal of the National Cancer Institute.
COUNTRY: UNITED STATES
TITLE: Studies with RP 56976 (taxotere): a semisynthetic analogue of taxol.
PUBDATE: 19910201
RP 56976 (taxotere), a new semisynthetic analogue of taxol, is a potentially important chemotherapeutic agent for the treatment of cancer. We report here that this drug is a potent inhibitor of cell replication and, like taxol, promotes the in vitro assembly of stable microtubules in the absence of guanosine triphosphate and induces microtubule-bundle formation in cells. Compared with taxol, RP 56976 is slightly more active as a promoter of tubulin polymerization. As an inhibitor of cell replication, RP 56976 is 2.5-fold more potent than taxol in J774.2 and P388 cells and at least 5-fold more potent in taxol-resistant cells.


12. DOCID:22126 SCORE: 0.00245186453801511
DOCNO: 8665179
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: P M Sagar PM
AUTHOR: J H Pemberton JH
AFFILIATION: Division of Colon and Rectal Surgery, Mayo Clinic, Rochester, Minnesota, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The British journal of surgery.
COUNTRY: ENGLAND
TITLE: Surgical management of locally recurrent rectal cancer.
PUBDATE: 19960301
The surgical management of locally recurrent rectal cancer may involve major procedures and is not for the faint-hearted. Nevertheless, such treatment is preferable to chemotherapy and radiotherapy; the latter will fail over a period of months during which the patient is likely to experience intractable pain. Radical surgery offers good palliation and a better quality of life. Survival is prolonged by such operations which may be curative in up to one-third of patients. Nevertheless, surgeons must be realistic in their assessment of and discussions with patients.


13. DOCID:18188 SCORE: 0.00230391115441147
DOCNO: 10119215
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Decision Making, Organizational
DESCRIPTOR: Licensure
QUALIFIER: economics
QUALIFIER: organization & administration
QUALIFIER: drug therapy
AUTHOR: M E Ross ME
AUTHOR: R L Nydick RL
PUBTYPE: Journal Article
JOURNALTITLE: Journal of health care marketing.
COUNTRY: UNITED STATES
TITLE: Selection of licensing candidates in the pharmaceutical industry: an application of the analytic hierarchy process.
PUBDATE: 19920601
The ethical (prescription) pharmaceutical industry depends on a stream of innovative, patent-protected products to maintain growth and profitability. With Sterling Drug's entry into a new therapeutic area (oncology, the study and treatment of cancer), licensing and research collaborations have become an important part of the process of developing a pipeline of potential new drugs. The application of the analytic hierarchy process has led to improved articulation of the relevant criteria and better definition of organizational procedures, thereby benefiting Sterling's decision-making process.


14. DOCID:22210 SCORE: 0.00229984463266673
DOCNO: 8708182
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Adaptation, Psychological
DESCRIPTOR: Complementary Therapies
DESCRIPTOR: Decision Making
DESCRIPTOR: Internal-External Control
QUALIFIER: psychology
QUALIFIER: therapy
AUTHOR: M J Montbriand MJ
AFFILIATION: Royal University Hospital, University of Saskatchewan, Saskatoon, Canada.
PUBTYPE: Journal Article
JOURNALTITLE: Journal of advanced nursing.
COUNTRY: ENGLAND
TITLE: Alternative therapies as control behaviours used by cancer patients.
PUBDATE: 19951001
Alternative health care practices are a way in which cancer patients can be in control of their illness situation. This assumption is investigated through control theory. While the sociocultural schemas of North American patients endorse control of illness, the stress of the cancer experience dismisses the advantage of control behaviours. Analysis also suggests that patients find ways to escape from the freedom of being in control of their health situation. This post-analysis of a recent study uncovers major ambiguities concerning the control behaviours of cancer patients.