0. DOCID:27836 SCORE: 0.00378585096165498
DOCNO: 10803401
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Peritoneovenous Shunt
QUALIFIER: diagnosis
QUALIFIER: therapy
AUTHOR: M Roskos M
AUTHOR: M B Popp MB
AFFILIATION: Department of Surgery, The Jewish Hospital, Cincinnati, Ohio, USA.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Surgical laparoscopy, endoscopy & percutaneous techniques.
COUNTRY: UNITED STATES
TITLE: Laparoscopic diagnosis and management of malignant ascites.
PUBDATE: 19991001
Malignancy is the second most common cause of ascites. Tissue diagnosis is often difficult because the cytology of ascitic fluid is positive in only 57% of cases. Peritoneovenous shunting is often used as palliation in such patients and has proven superior to nonoperative management for some patients. We present three cases of malignant ascites with negative cytologies managed by using laparoscopic biopsies to confirm intraperitoneal cancer and assist in the placement of a peritoneovenous shunt. Results suggest that exploratory laparoscopy and shunt placement is a valuable procedure in these patients with a limited life expectancy and is preferable to open laparotomy.


1. DOCID:31507 SCORE: 0.00335905761712167
DOCNO: 15776005
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Immune Tolerance
DESCRIPTOR: Tumor Escape
QUALIFIER: immunology
AUTHOR: Weiping Zou W
AFFILIATION: Tulane University Health Sciences Center, Section of Hematology and Medical Oncology, 1430 Tulane Avenue, New Orleans, Louisiana 70112-2699, USA. wzou@tulane.edu
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Nature reviews. Cancer.
COUNTRY: England
TITLE: Immunosuppressive networks in the tumour environment and their therapeutic relevance.
PUBDATE: 20050401
It is well known that many tumours are potentially immunogenic, as corroborated by the presence of tumour-specific immune responses in vivo. Nonetheless, spontaneous clearance of established tumours by endogenous immune mechanisms is rare. Therefore, the focus of most cancer immunotherapies is to supplement essential immunogenic elements to boost tumour-specific immunity. Why then has tumour immunotherapy resulted in a generally poor clinical efficiency? The reason might lie in the increasingly documented fact that tumours develop diverse strategies that escape tumour-specific immunity.


2. DOCID:23013 SCORE: 0.00323721237890395
DOCNO: 7853158
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Ankle Joint
QUALIFIER: diagnosis
QUALIFIER: diagnosis
QUALIFIER: pathology
AUTHOR: E E Leonheart EE
AUTHOR: J DiStazio J
AFFILIATION: Podiatry Hospital, Pittsburgh, PA.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Journal of the American Podiatric Medical Association.
COUNTRY: UNITED STATES
TITLE: Acrometastases. Initial presentation as diffuse ankle pain.
PUBDATE: 19941201
Acrometastases are rare and often misdiagnosed or overlooked. When it involves the feet, it generally attacks the larger bones containing the higher amounts of red marrow. The patient may or may not have a known history of cancer, which makes diagnosis much more difficult. The symptomatology is generally vague and can mimic other conditions, such as osteomyelitis, gouty rheumatoid arthritis, Reiter's syndrome, Paget's disease, osteochondral lesions, and ligamentous sprains. Therefore, the physician must consider metastatic disease in the differential diagnosis. Once the diagnosis is made, the prognosis is poor and treatment is limited to pain relief and maintaining function.


3. DOCID:25902 SCORE: 0.00313531098968199
DOCNO: 10642079
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Nutritional Support
QUALIFIER: metabolism
AUTHOR: A M Cooperman AM
AUTHOR: J Chivati J
AUTHOR: R S Chamberlain RS
AFFILIATION: Institute for Liver, Biliary and Pancreatic Surgery, Community Hospital of Dobbs Ferry, New York 10522, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Current opinion in clinical nutrition and metabolic care.
COUNTRY: ENGLAND
TITLE: Nutritional and metabolic aspects of pancreatic cancer.
PUBDATE: 20000101
Most patients with pancreatic cancer suffer from a variety of severe metabolic and nutritional disturbances. Despite this fact, the role of perioperative nutritional support for these patients remains controversial. This review highlights the results of randomized prospective clinical trials, and meta-analyses that have addressed this issue. The 'current opinion' put forth in this discussion is based on these reviews, and on personal observations in treating more than 500 patients.


4. DOCID:23288 SCORE: 0.00313177884316027
DOCNO: 8028292
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: ultrasonography
AUTHOR: T A Kirkland TA
AUTHOR: J E Lathem JE
AFFILIATION: Department of Urology, Medical University of South Carolina, Charleston 29425.
PUBTYPE: Journal Article
JOURNALTITLE: Journal of the South Carolina Medical Association (1975)
COUNTRY: UNITED STATES
TITLE: The role of transrectal ultrasound (TRUS) in the evaluation of cancer of the prostate.
PUBDATE: 19940501
While TRUS is not of value as a screening tool, it is of considerable value in the early detection of cancer of the prostate in men with abnormal DRE and/or PSA. TRUS enables calculation of PSA density to identify men at low risk, thus eliminating many unnecessary biopsies. This results in favorable impact on both cost and morbidity. When biopsy is necessary, TRUS greatly enhances accuracy. Its role in staging is of less importance but can be useful when positive, and it adds little to the cost or complexity of the examination.


5. DOCID:31377 SCORE: 0.00313100106558988
DOCNO: 15770817
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: etiology
QUALIFIER: drug therapy
AUTHOR: A Zouhair A
AUTHOR: P H Wiesel PH
AFFILIATION: Service de radio-oncologie, CHUV, 1011 Lausanne.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Revue médicale suisse.
COUNTRY: Switzerland
TITLE: [Non-surgical treatment of acute and late radiation proctitis]
PUBDATE: 20050101
Pelvic external radiotherapy with or without brachytherapy plays an important role in the management of pelvic cancers. Despite recent technical innovations including conformal three-dimensional (3D) external beam radiotherapy and more recently intensity modulated radiotherapy (IMRT), local side effects can occur secondary to normal tissue damage caused by ionising radiation. Morbidity depends on the anatomic position of the rectum within the pelvis and the fast turnover rate of the mucosa, as well as the characteristics of the radiation treatment and patient co-morbidities. Medical management is sometimes complex and merits herein a short review.


6. DOCID:19009 SCORE: 0.00308829815111136
DOCNO: 8405372
AUTHOR: J Knowland J
AUTHOR: E A McKenzie EA
AUTHOR: P J McHugh PJ
AUTHOR: N A Cridland NA
AFFILIATION: Department of Biochemistry, South Parks Road, Oxford OX1 3QU, UK.
PUBTYPE: Journal Article
JOURNALTITLE: FEBS letters.
COUNTRY: NETHERLANDS
TITLE: Sunlight-induced mutagenicity of a common sunscreen ingredient.
PUBDATE: 19930601
We have tested the mutagenicity of a UV-B sunscreen ingredient called Padimate-O or octyl dimethyl PABA, which, chemically speaking, is identical to an industrial chemical that generates free radicals when illuminated. It is harmless in the dark but mutagenic in sunlight, attacking DNA directly. A commercial sunscreen containing Padimate-O behaves in the same way. UV-A in sunlight also excites Padimate-O, although less than UV-B. Some related compounds, including a known carcinogen, behave similarly. As mutagens may be carcinogenic, our results suggest that some sunscreens could, while preventing sunburn, contribute to sunlight-related cancers.


7. DOCID:16731 SCORE: 0.00297523861186542
DOCNO: 1967109
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
QUALIFIER: administration & dosage
QUALIFIER: administration & dosage
QUALIFIER: methods
QUALIFIER: administration & dosage
QUALIFIER: therapy
AUTHOR: J Brahm J
AUTHOR: J Chesta J
AUTHOR: V Gaínza V
AUTHOR: V Arriagada V
AFFILIATION: Centro de Gastroenterología, Universidad de Chile, Santiago.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Revista médica de Chile.
COUNTRY: CHILE
TITLE: [Selective chemoembolization with adriamycin-Urografin-Lipiodol in the treatment of hepatocarcinoma]
PUBDATE: 19901001
Various methods of regional chemotherapy have been used in patients with non resectable heptic carcinoma. We report our preliminary experience with embolization using adriamycin-urographin-lipiodol in 2 patients with this cancer in whom a considerable reduction of tumoral mass was observed. The pertinent literature is briefly commented.


8. DOCID:27007 SCORE: 0.00291394736831368
DOCNO: 11783101
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: C Wang C
AUTHOR: T Ding T
AUTHOR: L Chang L
AFFILIATION: Shanxi Tumor Hospital, Taiyuan 030013, China.
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
PUBTYPE: Randomized Controlled Trial
JOURNALTITLE: Zhonghua zhong liu za zhi [Chinese journal of oncology].
COUNTRY: China
TITLE: [A randomized clinical study of preoperative chemotherapy for esophageal carcinoma]
PUBDATE: 20010501
OBJECTIVE: To evaluate the effect of preoperative chemotherapy on the prognosis of stage II or III patients with esophageal carcinoma. METHODS: From February 1991 to June 1994, 50 patients with stage II, III esophageal carcinoma were treated with preoperative combination (CDDP) chemotherapy and compared with 50 patients received operation alone. RESULTS: The 5-year survival rate of the operation group and preoperative chemotherapy group was 32% and 46%, respectively. The difference was statistically significant. CONCLUSION: Preoperative chemotherapy improves survival of surgically treated esophageal cancer patients.


9. DOCID:27769 SCORE: 0.00290612499120429
DOCNO: 11747925
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Accidents, Radiation
DESCRIPTOR: Nuclear Reactors
QUALIFIER: epidemiology
QUALIFIER: epidemiology
AUTHOR: Y Shibata Y
AUTHOR: S Yamashita S
AUTHOR: V B Masyakin VB
AUTHOR: G D Panasyuk GD
AUTHOR: S Nagataki S
PUBTYPE: Letter
JOURNALTITLE: Lancet.
COUNTRY: England
TITLE: 15 years after Chernobyl: new evidence of thyroid cancer.
PUBDATE: 20011201
The Chernobyl nuclear power plant accident happened on April 26, 1986. We investigated the cause of the striking increase in frequency of thyroid cancer in children who lived within a 150 km radius of Chernobyl and who were born before and after the accident. No thyroid cancer was seen in 9472 children born in 1987-89, whereas one and 31 thyroid cancers were recorded in 2409 children born April 27, 1986, to Dec 31, 1986, and 9720 born Jan 1, 1983, to April 26, 1986, respectively. Short-lived radioactive fallout caused by the Chernobyl accident probably induced thyroid cancer in children living near Chernobyl.


10. DOCID:31864 SCORE: 0.00283835906369146
DOCNO: 16224168
OWNER: NLM
STATUS: In-Process
AUTHOR: Sung Ho Song SH
AUTHOR: Ick Jang I
AUTHOR: Bum Sik Kim BS
AUTHOR: Eun Tak Kim ET
AUTHOR: Seung-Hyo Woo SH
AUTHOR: Mee Ja Park MJ
AUTHOR: Chang Nam Kim CN
AFFILIATION: Department of Urology, Eulji Medical University, Daejeon, Korea.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Journal of Korean medical science.
COUNTRY: Korea (South)
TITLE: A case of primary syphilis in the rectum.
PUBDATE: 20051001
A 30-yr-old man was referred for suspicious rectal cancer because of ulcerated lesions in the rectum and a palpable mass in left inguinal area. Sigmoidoscopy showed two indurated masses and histologic evaluation of biopsy revealed obliterative endarteritis with heavy plasma cell infiltration. Both venereal disease research laboratories (VDRL) and fluorescent treponemal antibody absorption (FTA-ABS) tests were positive. After injection of penicillin G benzathine for 3 weeks, the rectal chancre and the palpable mass disappeared.


11. DOCID:25104 SCORE: 0.00283553852944359
DOCNO: 11905809
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Pharmacogenetics
QUALIFIER: drug therapy
AUTHOR: M V Relling MV
AUTHOR: T Dervieux T
AFFILIATION: Department of Pharmaceutical Sciences, St Jude Children's Research Hospital, Memphis, Tennessee 38105, USA. mary.relling@stjude.org
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Nature reviews. Cancer.
COUNTRY: England
TITLE: Pharmacogenetics and cancer therapy.
PUBDATE: 20011101
Pharmacogenetics is the study of how genetic variations affect drug response. These variations can affect a patient's response to cancer drugs, for which there is usually a fine line between a dosage that has a therapeutic effect and one that produces toxicity. Gaining better insight into the genetic elements of both the patient and the tumour that affect drug efficacy will eventually allow for individualized dosage determination and fewer adverse effects.


12. DOCID:19326 SCORE: 0.0028004105711638
DOCNO: 1894956
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: W Lange W
AUTHOR: W Brugger W
AUTHOR: F M Rosenthal FM
AUTHOR: L Kanz L
AUTHOR: A Lindemann A
AFFILIATION: Albert-Ludwigs University Medical Center, Department of Hematology and Oncology, Freiburg, Germany.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: International journal of cell cloning.
COUNTRY: UNITED STATES
TITLE: The role of cytokines in oncology.
PUBDATE: 19910701
The availability of sufficient quantities of recombinant human cytokines and promising preclinical data have led to their introduction into clinical trials. Cytokines have potential as new therapeutic agents in a variety of hematological disorders as well as in solid tumors. Only a few of the still increasing number of these glycoprotein hormones have been studied in humans so far, either as single agents or in combination with chemotherapy and other cytokines. Their clinical effects, beneficial role in supportive care, and use in the treatment of certain cancer patients are reviewed.


13. DOCID:31514 SCORE: 0.00276781669502462
DOCNO: 15517115
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: methods
AUTHOR: J Weitz J
AUTHOR: M Koch M
AUTHOR: J Kleeff J
AUTHOR: M W Müller MW
AUTHOR: J Schmidt J
AUTHOR: H Friess H
AUTHOR: M W Büchler MW
AFFILIATION: Abteilung für Allgemein-, Visceral- und Unfallchirurgie, Chirurgische Universitätsklinik Heidelberg.
PUBTYPE: Journal Article
JOURNALTITLE: Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen.
COUNTRY: Germany
TITLE: [Kausch-Whipple pancreaticoduodenectomy. Technique and results]
PUBDATE: 20041101
The Kausch-Whipple operation is the standard procedure for resection of pancreatic head cancer, distal bile duct cancer, and periampullary cancers. It is also used for some cases of chronic pancreatitis. Traditionally, this operation is associated with high perioperative morbidity and mortality. The aim of our study was to present our current technique for Kausch-Whipple pancreaticoduodenectomy and to demonstrate that acceptable perioperative and long-term outcomes can be achieved by a standardised technique in a high-volume centre.


14. DOCID:30735 SCORE: 0.00275815881213456
DOCNO: 15013720
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Depsipeptides
QUALIFIER: analogs & derivatives
QUALIFIER: drug effects
QUALIFIER: drug effects
QUALIFIER: methods
QUALIFIER: drug therapy
QUALIFIER: genetics
AUTHOR: David S Schrump DS
AFFILIATION: Thoracic Oncology Section, Surgery Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892, USA. david_Schrump@nih.gov
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The Journal of surgical research.
COUNTRY: United States
TITLE: Genomic surgery for lung cancer.
PUBDATE: 20040301
An emerging body of literature indicates that reversible alterations in chromatin structure modulate gene expression during malignant transformation. Chromatin structure is regulated in part by DNA methylation and histone acetylation; these independent yet highly interrelated epigenetic processes are influenced by a variety of signal transduction pathways. The present review highlights recent advances regarding cancer epigenetics, focusing on the potential utilization of chromatin remodeling agents to induce apoptosis and enhance the immunogenicity of thoracic malignancies.