0. DOCID:15861 SCORE: 0.00697346652404484
DOCNO: 2481893
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Palliative Care
QUALIFIER: drug therapy
QUALIFIER: drug therapy
AUTHOR: L Gran L
AUTHOR: C F Borchgrevink CF
PUBTYPE: Journal Article
JOURNALTITLE: Tidsskrift for den Norske laegeforening.
COUNTRY: NORWAY
TITLE: [Pain treatment of patients with cancer]
PUBDATE: 19891101
In Vestfold, with a population of 192,200, all patients who died from cancer in 1987 were followed retrospectively through their last six months. 61% (n = 342) had cancer-related pain and received analgesic treatment. In 9% pain remained a problem. In the same group, 74% suffered from other symptoms, such as nausea, dyspnoea, anxiety and depression. These symptoms were reduced efficiently in only 58%. Nausea was the main problem. We found a significant connection between nausea, chemotherapy and opiate treatment. Anxiety and depression were recognised in about 20% of the patients, and were seldom adequately relieved. In order to provide optimal quality of life, more attention should be drawn not only to pain but also to the other symptoms.


1. DOCID:10566 SCORE: 0.00537244467955721
DOCNO: 6312623
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: etiology
QUALIFIER: adverse effects
QUALIFIER: pharmacology
AUTHOR: J L Trudel JL
AUTHOR: M K Senterman MK
AUTHOR: R A Brown RA
PUBTYPE: Journal Article
JOURNALTITLE: Surgery.
COUNTRY: UNITED STATES
TITLE: The fat/fiber antagonism in experimental colon carcinogenesis.
PUBDATE: 19831001
Current epidemiologic and experimental data emphasize the importance of nutrition in colon carcinogenesis. The interactions between dietary fat and dietary fiber were studied in the dimethylhydrazine model for colon cancer. A strict pair-feeding system was developed, and rats were fed one of five semisynthetic diets containing various amounts and types of fat and fiber. The incidence and number of tumors per animal were increased in all fat-fed groups. Adding fiber to the diets provided either partial (polyunsaturated fat) or complete (saturated fat) protection against the deleterious effect of fat. The antagonism between fat and fiber and the clinical relevance of these data are discussed.


2. DOCID:15611 SCORE: 0.00528771683351383
DOCNO: 3167795
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: prevention & control
QUALIFIER: prevention & control
AUTHOR: A W Kopf AW
AFFILIATION: Department of Dermatology, New York University School of Medicine, NY.
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Prevention and early detection of skin cancer/melanoma.
PUBDATE: 19881001
In the USA malignant neoplasms of the skin are the most common cancers of man. Annually, over 500,000 new cutaneous cancers are diagnosed. Of particular concern is the inexorable increase in the incidence and mortality rate of malignant melanoma (in 1978: 25,000 new cases; 5800 deaths). There are substantial data that (1) implicate sunlight as the probable cause of many cancers of the skin, and that, (2) indicate early diagnosis and prompt treatment results in cure in most instances. The time has come to create, implement, and evaluate a National Program on Education of the Medical Profession and the Public on Cancers of the Skin with emphasis on cutaneous malignant melanoma.


3. DOCID:11552 SCORE: 0.00524582242426296
DOCNO: 6645064
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
AUTHOR: H Konno H
AUTHOR: K Okuyama K
AUTHOR: K Isono K
AUTHOR: S Onoda S
AUTHOR: H Hirasawa H
AUTHOR: H Satoh H
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [Thoracic esophageal cancer in a young adult]
PUBDATE: 19831001
A 34-year-old Japanese male was admitted to the Second Department of Surgery, Chiba University Hospital complaining of swallowing difficulties of three months duration. Radiological examination with barium swallowing revealed thoracic esophageal cancer, classified as EiEa, was 6cm long and of the serrated type. Preoperative combined therapy included Fast Neutron, Pepleomycin, Bestatin and hyperthermia. The operative procedure was total thoracic esophagectomy and ante-thoracic esophago-gastrostomy using the right thoracotomy approach plus laparotomy. Postoperative combined therapy included Linac irradiation and Cisplatin. His postoperative course was uneventful and he was discharged without complications. The tumor was of ill-defined ulcerative type macroscopically; the pathological diagnosis was moderately differentiated squamous cell carcinoma.


4. DOCID:14451 SCORE: 0.00518945829471893
DOCNO: 3436510
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Vaginal Smears
QUALIFIER: secondary
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: secondary
AUTHOR: V Jaluvka V
AUTHOR: W Engelhardt W
AFFILIATION: Frauenklinik und Poliklinik, Freien Universität im Klinikum Steglitz.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Geburtshilfe und Frauenheilkunde.
COUNTRY: GERMANY, WEST
TITLE: [Cervix cytology and primary malignancies of the gastrointestinal tract]
PUBDATE: 19871201
During the cancer check-up of a 46-year-old woman a PAP V was diagnosed in the cervical scrapings. The atypical cells of the abrasion specimens from the corpus uteri arouse strong suspicion of malignancy. Connected with the clinical data, this finding primarily indicated a metastatic involvement of the inner genitals. This suspicion was confirmed by exploratory surgery laparotomy. A large tumor was found intraoperatively which was occupying the entire stomach. Concurrently, a diffuse peritoneal carcinomatosis was found with involvement of the left adnexae in the sense of a Krukenberg's tumor.


5. DOCID:15359 SCORE: 0.00470382335156632
DOCNO: 2820741
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: drug therapy
AUTHOR: D A Morgan DA
AUTHOR: D Gilson D
AUTHOR: J Fletcher J
AFFILIATION: Hogarth Centre of Radiotherapy and Oncology, General Hospital, Nottingham, England.
PUBTYPE: Journal Article
JOURNALTITLE: European journal of cancer & clinical oncology.
COUNTRY: ENGLAND
TITLE: Vincristine and etoposide: an effective chemotherapy regimen with reduced toxicity in extensive small-cell lung cancer.
PUBDATE: 19870601
Chemotherapy prolongs survival of patients with small-cell lung cancer, but very few are cured, and the treatment is unpleasant. Thirty patients, 28 with advanced disease, were treated with etoposide 250 mg/m2 orally, daily for 5 days, plus vincristine 2 mg intravenously on the first day, the cycle being repeated 3-weekly, to a maximum of 6. There was a response rate of 70%, a median survival of 249 days, and an 11% 2-year survival. Symptomatic side-effects were less pronounced than with most other regimens of comparable efficacy.


6. DOCID:14776 SCORE: 0.00469442942094938
DOCNO: 3172524
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: etiology
QUALIFIER: therapy
QUALIFIER: therapeutic use
AUTHOR: R Nakamura R
AUTHOR: M Watanabe M
AUTHOR: Y Sugimura Y
AUTHOR: M Kondoh M
AUTHOR: K Saitoh K
AUTHOR: S Sasou S
AFFILIATION: Dept. of Surgery I, Iwate Medical Univ., School of Med.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [Early esophageal cancer discovered 6 months after endoscopic injection sclerotherapy of esophageal varices]
PUBDATE: 19880801
Early esophageal cancer was discovered in a 55-year-old male with liver cirrhosis six months after the start of treatment for esophageal varices by a series of endoscopic sclerotherapeutic injections using 5% ethanolamine oleate. A histological examination of the entire length of the resected esophageal wall revealed a carcinomatous lesion oralwards and far removed from the lesion where subsequent changes due to sclerotherapy were prominent. Further, the causal relationship between sclerotherapy and carcinoma is discussed.


7. DOCID:11395 SCORE: 0.00450680410195997
DOCNO: 6884824
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
QUALIFIER: therapeutic use
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
AUTHOR: D Nori D
AUTHOR: J M Cain JM
AUTHOR: B S Hilaris BS
AUTHOR: W B Jones WB
AUTHOR: J L Lewis JL
PUBTYPE: Journal Article
JOURNALTITLE: Gynecologic oncology.
COUNTRY: UNITED STATES
TITLE: Metronidazole as a radiosensitizer and high-dose radiation in advanced vulvovaginal malignancies, a pilot study.
PUBDATE: 19830801
Advanced vulvovaginal cancers have a survival of less than 25% in 5 years when treated with radiotherapy alone. The radiosensitizer metronidazole was used with unconventional radiation fractions in 10 patients. Local control was achieved in 9 out of 10 patients treated. Five of 10 patients have remained free of disease 9-30 months postdiagnosis. Two patients died with metastatic disease, but with local control. In only 1 patient did this approach fail to control local disease. The outcome of these 10 patients represents a significant improvement over conventional radiation. A randomized prospective study has been started on the basis of this pilot study.


8. DOCID:11193 SCORE: 0.00450486553275067
DOCNO: 2995755
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
QUALIFIER: therapy
QUALIFIER: therapy
QUALIFIER: methods
QUALIFIER: therapy
QUALIFIER: methods
AUTHOR: S L Dar'ialova SL
AUTHOR: P G Bitiutskiĭ PG
AUTHOR: V A Sukirko VA
AUTHOR: A L Klochikhin AL
AUTHOR: G A Frank GA
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
PUBTYPE: Randomized Controlled Trial
JOURNALTITLE: Meditsinskaia radiologiia.
COUNTRY: USSR
TITLE: [Preoperative irradiation of laryngeal cancer patients under different oxygen regimens]
PUBDATE: 19850901
Radiation therapy under the conditions of hyperbaric oxygenation (HBO) using the method of mean fractionation (3.3 Gy 3 times a week up to the summary dose of 33 Gy) was employed to overcome tumor hypoxia and to raise selectively radiosensitivity of laryngeal cancer. A randomized study of 120 patients has shown that the use of radiation therapy under HBO conditions makes it possible to reduce the frequency of radiation reactions, to increase tumor resorption and the degree of radiation damage, to reduce the frequency of postoperative purulent complications, and to prevent the occurrence of early and late recurrences and metastases.


9. DOCID:12816 SCORE: 0.00427236357136497
DOCNO: 3627614
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Pelvic Exenteration
QUALIFIER: transplantation
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: J E Delmore JE
AUTHOR: D A Turner DA
AUTHOR: D M Gershenson DM
AUTHOR: D V Horbelt DV
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Obstetrics and gynecology.
COUNTRY: UNITED STATES
TITLE: Perineal hernia repair using human dura.
PUBDATE: 19870901
A patient developed a large perineal hernia and prolapse of a myocutaneous neovagina 13 months after total pelvic exenteration for recurrent squamous cell cancer of the cervix and gracilis myocutaneous vaginal reconstruction. The neovagina was removed and the pelvic floor defect was repaired with preserved human dura. Twelve months postoperatively, the patient remained asymptomatic. Current and potential uses for human dura allografts are discussed.


10. DOCID:10805 SCORE: 0.00421163139045689
DOCNO: 6525600
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
AUTHOR: G Ehninger G
AUTHOR: K H Weible KH
AUTHOR: E G Heidemann EG
AUTHOR: H D Waller HD
PUBTYPE: Journal Article
JOURNALTITLE: Cancer treatment reports.
COUNTRY: UNITED STATES
TITLE: Mitoxantrone and cyclophosphamide in patients with advanced breast cancer.
PUBDATE: 19841001
Twenty-eight patients with advanced breast cancer who had no prior chemotherapy received 14 mg/m2 of mitoxantrone iv on Day 1 and 600 mg/m2 of cyclophosphamide on Day 2, repeated every 4 weeks. Three patients (10%) achieved complete response and ten (36%) achieved partial response. The dose-limiting toxicity was leukopenia, and no septicemia occurred. Slightly greater than 50% of the patients had a wbc count nadir less than 2000/mm3. Based on the remarkably good tolerability, ie, mild nausea, rarely severe alopecia, and observed remission rate, this combination represents a positive addition to chemotherapy for advanced breast cancer.


11. DOCID:11088 SCORE: 0.00418477912476748
DOCNO: 6737706
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: prevention & control
AUTHOR: T Hirayama T
PUBTYPE: Journal Article
JOURNALTITLE: Japanese journal of clinical oncology.
COUNTRY: JAPAN
TITLE: Epidemiology of stomach cancer in Japan. With special reference to the strategy for the primary prevention.
PUBDATE: 19840601
Characteristics of both descriptive and analytic epidemiology of stomach cancer were summarised. Dietary changes, especially reduced intake of salted food mainly due to the wider use of electric refrigerator, were considered as the major reasons of recent decline in mortality. Other features of descriptive epidemiology such as socio-economic variation, lower risk in Okinawa residents and Japanese migrants to the U.S.A. were also described. In analytic epidemiology, daily cigarette smoking was found as a risk-enhancing factor in addition to frequent intake of salted food. Daily intake of green-yellow vegetables, soybean paste soup and milk were considered as risk reducing factors. Possibilities of primary prevention of stomach cancer was discussed based on these findings.


12. DOCID:15438 SCORE: 0.00399178320094375
DOCNO: 3307257
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: surgery
AUTHOR: A Viste A
AUTHOR: G E Eide GE
AUTHOR: O Søreide O
PUBTYPE: Journal Article
JOURNALTITLE: Acta chirurgica Scandinavica.
COUNTRY: SWEDEN
TITLE: Stomach cancer: a prospective study of anastomotic failure following total gastrectomy.
PUBDATE: 19870401
The incidence and cause of esophagojejunal anastomotic leakage were prospectively studied in 350 patients following total gastrectomy for stomach cancer. Anastomotic leak was demonstrated in 30 patients (8.6%), ten of whom underwent reoperation. Nine of the 30 patients died. Statistical analysis revealed that the outcome was better for patients with stapled esophagojejunostomy than when the anastomosis was hand-sutured. The odds for leakage were 2.37 times higher in patients with hand-sutured, than in those with stapled anastomosis. Antibiotic prophylaxis may be significant in preventing leakage. No association was found between anastomotic leakage and type of hospital, patient age or sex, preoperative weight loss, concomitant splenectomy or residual tumor in the resection margin.


13. DOCID:15342 SCORE: 0.00382762271812327
DOCNO: 2461645
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: methods
QUALIFIER: surgery
AUTHOR: H Nakajima H
AUTHOR: K Mori K
AUTHOR: S Ohnishi S
AUTHOR: S Kato S
AUTHOR: H Tanda H
AFFILIATION: Sanjukai Hospital.
PUBTYPE: Journal Article
JOURNALTITLE: Hinyokika kiyo. Acta urologica Japonica.
COUNTRY: JAPAN
TITLE: [Clinical studies of transurethral resection in patients with benign prostatic hypertrophy]
PUBDATE: 19880801
During the last 9 years, 1,892 patients underwent surgery of the prostate. Benign prostatic hypertrophy (BPH) accounted for 1,812 cases, and prostatic cancer 80 cases. In the case of BPH, transurethral resection was done in 1,645 cases, cryosurgery in 136 cases, and suprapubic prostatectomy in 31 cases. Latent cancer was detected in 54 (3.3%) of the BPH cases. The average patient age of the patients with latent cancer (73.6 +/- 6.9 years) was higher than that of those without latent cancer (69.5 +/- 7.7 years). This suggested a significant relationship between the age of the patient and the occurrence of latent cancer.


14. DOCID:14272 SCORE: 0.00379591068945241
DOCNO: 2777441
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: chemically induced
AUTHOR: T Y Chuang TY
AUTHOR: J Tse J
AUTHOR: D J Cripps DJ
AFFILIATION: Dermatology Section, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin.
PUBTYPE: Journal Article
JOURNALTITLE: International journal of dermatology.
COUNTRY: UNITED STATES
TITLE: A preliminary study on the link between PUVA and skin cancer.
PUBDATE: 19890901
One hundred four psoriatic patients who had 8-methoxypsoralen-ultraviolet light A (PUVA) treatment between 1975-1987 were investigated to determine if skin cancer had ever occurred during or after the therapeutic period. Incidence data of skin cancer was applied to this group of patients to measure the expected number of patients with skin cancer. The significance of observed number versus expected of PUVA-treated patients with skin cancer was analyzed. The authors did not observe a significant increase of patients with skin cancer.