0. DOCID:24375 SCORE: 0.00173444107128832
DOCNO: 10373991
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: therapeutic use
QUALIFIER: therapy
QUALIFIER: therapy
AUTHOR: L K Swibold LK
AFFILIATION: Veterans Affairs Medical Center, Tucson, AZ, USA.
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
JOURNALTITLE: Urologic nursing : official journal of the American Urological Association Allied.
COUNTRY: UNITED STATES
TITLE: Maintenance therapy with bacillus Calmette-Guerin in patients with superficial bladder cancer.
PUBDATE: 19990301
The effectiveness of intravesical therapy with bacillus Calmette-Guerin for the treatment of superficial bladder cancer has been well established. However, there is no consensus about the optimum regimen for administering BCG. Maintenance therapy in 28 patients, results, and complications are addressed.

1. DOCID:26635 SCORE: 0.00113507627730883
DOCNO: 11720739
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Genes, Tumor Suppressor
DESCRIPTOR: Genetic Predisposition to Disease
QUALIFIER: genetics
QUALIFIER: physiopathology
QUALIFIER: genetics
QUALIFIER: physiopathology
QUALIFIER: genetics
QUALIFIER: physiopathology
AUTHOR: F J Kaye FJ
AFFILIATION: Genetics Branch, Center for Cancer Research, National Cancer Institute-Navy Oncology and National Naval Medical Center, Naval Hospital, Building 8/Room 5105, Bethesda, MD 20889, USA. fkaye@helix.nih.com
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Lung cancer (Amsterdam, Netherlands)
COUNTRY: Ireland
TITLE: Molecular biology of lung cancer.
PUBDATE: 20011201
Lung cancer develops slowly over many years from the sequential accumulation of gene alterations in susceptible pulmonary cells. The global epidemic of tobacco addiction has accelerated the incidence of lung cancer and has now focused increased attention on this disease worldwide. This review will briefly outline some of the tumor suppressor gene pathways that are known or suspected to play an important role in the development of this deadly malignancy.

2. DOCID:27475 SCORE: 0.00113462086584927
DOCNO: 10658734
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Coal
DESCRIPTOR: Tomography, X-Ray Computed
QUALIFIER: radiography
QUALIFIER: radiography
AUTHOR: H Y Kim HY
AUTHOR: J G Im JG
AUTHOR: J M Goo JM
AUTHOR: J Y Kim JY
AUTHOR: S K Han SK
AUTHOR: J K Lee JK
AUTHOR: J W Song JW
AFFILIATION: Department of Radiology and the Institute of Radiation Medicine MRC, Seoul National University, College of Medicine, Korea.
PUBTYPE: Journal Article
JOURNALTITLE: AJR. American journal of roentgenology.
COUNTRY: UNITED STATES
TITLE: Bronchial anthracofibrosis (inflammatory bronchial stenosis with anthracotic pigmentation): CT findings.
PUBDATE: 20000201
OBJECTIVE: The aim of this study was to describe CT findings of patients with bronchial anthracofibrosis. CONCLUSION: Atelectasis caused by smooth bronchial narrowing, surrounded by calcified or noncalcified lymph nodes, in elderly and nonsmoking women is a typical finding of anthracofibrosis. Calcified lymph nodes adjacent to the involved bronchi and multifocal involvement of bronchial narrowing may be helpful in differentiating this condition from lung cancer.

3. DOCID:24796 SCORE: 0.0011345803356567
DOCNO: 10208958
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Mutation
QUALIFIER: genetics
QUALIFIER: genetics
AUTHOR: P Weber P
AUTHOR: V Keim V
AUTHOR: K P Zimmer KP
AFFILIATION: University Children's Hospital, CH-4005 Basel, Switzerland.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Archives of disease in childhood.
COUNTRY: ENGLAND
TITLE: Hereditary pancreatitis and mutation of the trypsinogen gene.
PUBDATE: 19990501
Hereditary pancreatitis is a rare form of chronic recurrent pancreatitis. A family, in which 11 members had chronic pancreatitis, five had diabetes, and two had pancreatic cancer, was studied, and hereditary pancreatitis was diagnosed in all patients by demonstrating the mutation in exon 3 of the cationic trypsinogen gene (R117H). The clinical implications of genotypic analysis in hereditary pancreatitis are discussed.

4. DOCID:26958 SCORE: 0.000836473525896896
DOCNO: 10374686
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: secondary
QUALIFIER: pathology
QUALIFIER: secondary
AUTHOR: A Giuliani A
AUTHOR: A Caporale A
AUTHOR: M Di Bari M
AUTHOR: M Demoro M
AUTHOR: P Mingazzini P
AFFILIATION: Istituto I Clinica Chirurgica, Università La Sapienza, Rome, Italy.
PUBTYPE: Journal Article
JOURNALTITLE: Journal of experimental & clinical cancer research : CR.
COUNTRY: ITALY
TITLE: Isolated splenic metastasis from endometrial carcinoma.
PUBDATE: 19990301
Splenic involvement by carcinomatous metastases occurs late in the course of widely disseminated disease. Solitary metastasis to the spleen from a primary of any source is an uncommon event. We report a case of a 58-year-old woman in which an asymptomatic solitary metastatic endometrial adenocarcinoma of the spleen was detected 28 months after resection of the primary malignancy and treated by splenectomy. There are thirteen other reported cases of solitary splenic metastasis from gynecological cancers; in four of these reports the source was endometrial.

5. DOCID:26825 SCORE: 0.000836435085963999
DOCNO: 11380352
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: psychology
QUALIFIER: etiology
AUTHOR: F J Andrews FJ
AFFILIATION: BreastScreen Victoria Inc., Carlton, Victoria, Australia. fionaa@breastscreen.org.au
PUBTYPE: Journal Article
JOURNALTITLE: Australasian radiology.
COUNTRY: Australia
TITLE: Pain during mammography: implications for breast screening programmes.
PUBDATE: 20010501
Pain experienced during mammography can deter women from attending for breast cancer screening. Review of the current literature on pain experienced during mammography reveals three main areas of interest: reports of the frequency of pain, identification of predictors of pain and strategies for responding to pain. Implications of this literature for breast screening programmes include the need for appropriate measurements of pain during mammography that are valid for screening populations, a further understanding of organizational factors involved in screening programmes that may be predictors of pain and for the development of valid strategies for responding to pain within breast screening programmes.

6. DOCID:26957 SCORE: 0.00083641662050984
DOCNO: 10399438
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: ultrastructure
QUALIFIER: pathology
QUALIFIER: ultrastructure
QUALIFIER: ultrastructure
QUALIFIER: ultrastructure
QUALIFIER: ultrastructure
AUTHOR: V I Tsygankov VI
AUTHOR: S I Shvets SI
AUTHOR: G L Mogileva GL
AUTHOR: V M Kindialov VM
AUTHOR: N P Mel'nikova NP
PUBTYPE: Journal Article
JOURNALTITLE: Klinicheskaia laboratornaia diagnostika.
COUNTRY: RUSSIA
TITLE: [The nuclear morphotypes of epithelial cells in breast diseases]
PUBDATE: 19990501
Staining of the nucleolar ribosome organizer with AgNO3 followed by computer analysis of images by discriminant analysis helped distinguish 6 morphological types in the cells of cytological preparations of mammary glands. Comparison of the morphometrical data and results of visual examination of cells showed that the first type included nonproliferating fibroadenoma and mastopathy, type 2 fibroadenoma and mastopathy with moderate proliferation of epithelium, type 3 fibroadenoma and mastopathy with precancer epithelial proliferation, and types 4-6 included malignant proliferating cells which are compatible with well, moderately, and poorly differentiated cancer.

7. DOCID:26417 SCORE: 0.000836406575152935
DOCNO: 9973959
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Chromosome Aberrations
DESCRIPTOR: Chromosome Disorders
QUALIFIER: genetics
QUALIFIER: pathology
AUTHOR: L A Espinoza LA
AUTHOR: J Barbieri Neto J
AUTHOR: C Casartelli C
AFFILIATION: Departamento de Genética, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Brazil.
PUBTYPE: Journal Article
JOURNALTITLE: Cancer genetics and cytogenetics.
COUNTRY: UNITED STATES
TITLE: Pathological and karyotypic abnormalities in advanced gastric carcinomas.
PUBDATE: 19990201
Twenty samples of stomach cancers were analyzed by conventional cytogenetic and histopathological techniques. Nineteen tumors were diagnosed as adenocarcinomas and one as an adenosquamous carcinoma. Multiple and complex chromosomal abnormalities were found in the cases evaluated cytogenetically. This heterogeneity of chromosomal changes appears to indicate a certain correlation with tumor progression. Histological analysis showed a distinctive growth pattern of gastric cancer samples and a potential for invasiveness and recurrence for all tumors as well as a poor prognosis.

8. DOCID:26862 SCORE: 0.000836406574017769
DOCNO: 10664673
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
AUTHOR: E J Small EJ
AUTHOR: D M Reese DM
AFFILIATION: Department of Medicine, University of California San Francisco, USA. smalle@medicine.ucsf.edu
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Radiologic clinics of North America.
COUNTRY: UNITED STATES
TITLE: New treatment strategies in advanced prostate cancer.
PUBDATE: 20000101
The treatment of advanced prostate cancer has evolved rapidly in the last 5 years. Therapeutic options for patients with advanced disease, once essentially limited to the use of androgen deprivation, have expanded to include a number of interventions, including secondary hormonal manipulations, chemotherapy, and a variety of investigational approaches. Novel therapeutic approaches in prostate cancer patients are likely to be undertaken in patients with disease that is at or below the limits of detection by current imaging technology, so novel methods will be essential to the successful evaluation and use of these agents.

9. DOCID:24794 SCORE: 0.000836376993850022
DOCNO: 10680733
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Insulin-Like Growth Factor I
QUALIFIER: etiology
AUTHOR: A L Cradock AL
AFFILIATION: Department of Health and Social Behavior, Harvard School of Public Health, Boston, MA, USA.
PUBTYPE: Congresses
JOURNALTITLE: Cancer causes & control : CCC.
COUNTRY: NETHERLANDS
TITLE: Research questions concerning insulin-like growth factor-1.
PUBDATE: 20000101
The Harvard Center for Cancer Prevention (HCCP) convened a workshop on June 4, 1999 in Boston, MA. The objectives of the meeting were to briefly review the current state of knowledge in the area of insulin-like growth factor-1 physiology as related to cancer risk, to define the area's major remaining gaps in knowledge, and lastly to discuss research opportunities.

10. DOCID:27607 SCORE: 0.000836322678853094
DOCNO: 9820032
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Genes, Tumor Suppressor
DESCRIPTOR: Ligases
DESCRIPTOR: Tumor Suppressor Proteins
DESCRIPTOR: Ubiquitin-Protein Ligases
QUALIFIER: genetics
QUALIFIER: genetics
AUTHOR: W G Kaelin WG
AUTHOR: E R Maher ER
AFFILIATION: Division of Adult Oncology, Dana-Farber Cancer Hospital, Boston, MA, USA. william_kaelin@macmailgw.dfci.harvard.edu
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Trends in genetics : TIG.
COUNTRY: ENGLAND
TITLE: The VHL tumour-suppressor gene paradigm.
PUBDATE: 19981001
The VHL tumour-suppressor gene (TSG) has a critical 'gatekeeper' role in regulating growth and differentiation of human kidney cells, and inactivation of the VHL gene is the most frequent genetic event in human kidney cancer. There are many similarities between the genetics of the VHL and retinoblastoma TSGs, but the VHL tumourigenesis model is more complex. Here, we examine the current knowledge of the genetics and functional aspects of the VHL TSG, and emphasize how the VHL gene provides a paradigm that illustrates many aspects of TSG biology.

11. DOCID:27549 SCORE: 0.000836227900877392
DOCNO: 11242659
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: standards
AUTHOR: M Shimoyama M
AFFILIATION: Nagoya National Hospital, 4-1-1 Sannomaru, Naka-ku, Nagoya 460-0001, Japan.
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: Japan
TITLE: [Guideline for phase I study on new anticancer agents]
PUBDATE: 20010201
Since more than 50% of patients with cancer could no be cured by present standard therapy, new effective anticancer agents are needed in clinical level. In the evaluation of new anti-cancer agents by phase I study, there are several important and specific issues from scientific, medical, statistical, and ethical view points. Clinical safety data management is critically important in phase I study. This paper shows major parts of a report entitled "Guideline for phase I study on new anticancer agents", already published in JPs Pharmacol Ther 26: 441-454, 1998, with minor modification in order to answer these issues.

12. DOCID:27304 SCORE: 0.000836128094980561
DOCNO: 10630224
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Palliative Care
DESCRIPTOR: Patient Care Team
DESCRIPTOR: Pharmacists
AUTHOR: T Ishiguro T
AUTHOR: M Takahashi M
AUTHOR: H Kato H
AUTHOR: C Abe C
AUTHOR: A Shioya A
AUTHOR: T Ishiguro T
AUTHOR: T Yoshizawa T
AUTHOR: A Yoshizawa A
AFFILIATION: Dept. of Pharmacy, Kaname-cho Hospital.
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [Role of pharmacists in the medical team--attempting palliative care]
PUBDATE: 19991201
The Pharmacy Department at our hospital is attempting to develop methods for palliative care, for example of cancer pain or smelly tumors. The participation of pharmacists on the medical team for home care is necessary, because the supply of proper drugs for patients' individual conditions is indispensable in palliative care. Communication between not only patients, but also between their families and us, as well as the maintenance of close contact with the medical team, are important in home care.

13. DOCID:27376 SCORE: 0.000834614468048878
DOCNO: 10494319
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: blood
QUALIFIER: diagnosis
QUALIFIER: immunology
QUALIFIER: blood
AUTHOR: L F Wymenga LF
AUTHOR: H J Mensink HJ
AFFILIATION: Martini Ziekenhuis, afd. Urologie, Groningen.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Nederlands tijdschrift voor geneeskunde.
COUNTRY: NETHERLANDS
TITLE: [Prostate-specific antigen as a tumor marker of prostate carcinoma]
PUBDATE: 19990801
Prostate specific antigen (PSA) is currently the tumour marker of choice for prostatic carcinoma. Various indices of PSA have been developed in an attempt to refine its sensitivity and improve its clinical value. These include the ratio of serum PSA level and prostate volume, the rate of change of the PSA level with time, age-referenced PSA, and the proportion of free PSA in serum relative to total PSA (free to total PSA ratio). The free to total PSA ratio is lower in patients with prostate cancer than in those with elevated PSA levels due to benign prostatic hyperplasia.

14. DOCID:27412 SCORE: 0.000834614455143828
DOCNO: 14538145
OWNER: NLM
STATUS: PubMed-not-MEDLINE
AUTHOR: S Scheinbach S
AFFILIATION: Nabisco Research, Schaeberle Technology Center, 200 DeForest Ave., E. Hanover, New Jersey 07936, USA. ScheinbachS@Nabisco.com
PUBTYPE: Journal Article
JOURNALTITLE: Biotechnology advances.
COUNTRY: England
TITLE: Probiotics: functionality and commercial status.
PUBDATE: 19980501
Probiotics in the form of fermented milk products have been consumed for centuries. In this century various health benefits have been purported to result from consumption of foods containing live microorganisms, particularly lactic acid bacteria (LAB). Probiotics can provide relief for lactose intolerant individuals and reduce bouts of diarrhea. Evidence for other claims such as lowering serum cholesterol, suppressing cancer and stimulating the immune system remains to be clearly established by conducting well-controlled, statistically-valid clinical trials. Although the benefits to healthy individuals are uncertain, many consumers especially in Japan and Europe, perceive probiotic products to be healthful, and sales are robust.