0. DOCID:24375 SCORE: 0.00173444107128832
DOCNO: 10373991
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: therapeutic use
QUALIFIER: therapy
QUALIFIER: therapy
AUTHOR: L K Swibold LK
AFFILIATION: Veterans Affairs Medical Center, Tucson, AZ, USA.
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
JOURNALTITLE: Urologic nursing : official journal of the American Urological Association Allied.
COUNTRY: UNITED STATES
TITLE: Maintenance therapy with bacillus Calmette-Guerin in patients with superficial bladder cancer.
PUBDATE: 19990301
The effectiveness of intravesical therapy with bacillus Calmette-Guerin for the treatment of superficial bladder cancer has been well established. However, there is no consensus about the optimum regimen for administering BCG. Maintenance therapy in 28 patients, results, and complications are addressed.


1. DOCID:28372 SCORE: 0.00118876643604928
DOCNO: 15989555
OWNER: NLM
STATUS: MEDLINE
AUTHOR: Michael A Morse MA
AFFILIATION: Department of Medicine, Duke University Medical Center, Durham, NC, USA. m.morse@cgct.duke.edu
PUBTYPE: Journal Article
JOURNALTITLE: Expert opinion on emerging drugs.
COUNTRY: England
TITLE: 38th Annual Meeting of the American Society of Clinical Oncology. 18-21 May 2002, Orlando, Florida, USA.
PUBDATE: 20021001
The American Society of Clinical Oncology 38th Annual Meeting has continued to showcase an increasing number of biological and targeted therapies for the treatment of cancer and its complications. This review will provide an overview of the posters and presentations describing novel biological agents.


2. DOCID:28814 SCORE: 0.00116562519851629
DOCNO: 12371585
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Sentinel Lymph Node Biopsy
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: Alex G Little AG
AFFILIATION: Department of Surgery, University of Nevada, School of Medicine, Las Vegas 89102, USA. alittle@med.unr.edu
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The Surgical clinics of North America.
COUNTRY: United States
TITLE: Sentinel node biopsy for staging lung cancer.
PUBDATE: 20020601
The importance and value of accurate clinical and pathological staging of lung cancer is emphasized. The philosophy, techniques, and general results of the sentinel node technique for lymphatic mapping are reviewed. The experience with this technique in patients with non-small cell lung cancer is discussed and the future use of lymphatic mapping is pondered.


3. DOCID:29645 SCORE: 0.00115778659645615
DOCNO: 14686738
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: immunology
QUALIFIER: blood
QUALIFIER: complications
QUALIFIER: etiology
AUTHOR: David Schiff D
AUTHOR: Josep Dalmau J
AUTHOR: Delynne J Myers DJ
AFFILIATION: Department of Neurological Surgery, University of Pittsburgh Medical Center, USA. ds4jd@virginia.edu
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Journal of neuro-oncology.
COUNTRY: Netherlands
TITLE: Anti-GAD antibody positive stiff-limb syndrome in multiple myeloma.
PUBDATE: 20031101
Although most cases of stiff-limb syndrome are unassociated with malignancy, occasional cases have been associated with breast and lung cancer. Only four reported patients have had cancer and stiff-limb syndrome associated with anti-GAD antibodies. We report the first case of stiff-limb syndrome in a patient with multiple myeloma undergoing treatment with thalidomide, and explore the potential link to the cancer and its treatment.


4. DOCID:26635 SCORE: 0.00113507627730883
DOCNO: 11720739
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Genes, Tumor Suppressor
DESCRIPTOR: Genetic Predisposition to Disease
QUALIFIER: genetics
QUALIFIER: physiopathology
QUALIFIER: genetics
QUALIFIER: physiopathology
QUALIFIER: genetics
QUALIFIER: physiopathology
AUTHOR: F J Kaye FJ
AFFILIATION: Genetics Branch, Center for Cancer Research, National Cancer Institute-Navy Oncology and National Naval Medical Center, Naval Hospital, Building 8/Room 5105, Bethesda, MD 20889, USA. fkaye@helix.nih.com
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Lung cancer (Amsterdam, Netherlands)
COUNTRY: Ireland
TITLE: Molecular biology of lung cancer.
PUBDATE: 20011201
Lung cancer develops slowly over many years from the sequential accumulation of gene alterations in susceptible pulmonary cells. The global epidemic of tobacco addiction has accelerated the incidence of lung cancer and has now focused increased attention on this disease worldwide. This review will briefly outline some of the tumor suppressor gene pathways that are known or suspected to play an important role in the development of this deadly malignancy.


5. DOCID:27475 SCORE: 0.00113462086584927
DOCNO: 10658734
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Coal
DESCRIPTOR: Tomography, X-Ray Computed
QUALIFIER: radiography
QUALIFIER: radiography
AUTHOR: H Y Kim HY
AUTHOR: J G Im JG
AUTHOR: J M Goo JM
AUTHOR: J Y Kim JY
AUTHOR: S K Han SK
AUTHOR: J K Lee JK
AUTHOR: J W Song JW
AFFILIATION: Department of Radiology and the Institute of Radiation Medicine MRC, Seoul National University, College of Medicine, Korea.
PUBTYPE: Journal Article
JOURNALTITLE: AJR. American journal of roentgenology.
COUNTRY: UNITED STATES
TITLE: Bronchial anthracofibrosis (inflammatory bronchial stenosis with anthracotic pigmentation): CT findings.
PUBDATE: 20000201
OBJECTIVE: The aim of this study was to describe CT findings of patients with bronchial anthracofibrosis. CONCLUSION: Atelectasis caused by smooth bronchial narrowing, surrounded by calcified or noncalcified lymph nodes, in elderly and nonsmoking women is a typical finding of anthracofibrosis. Calcified lymph nodes adjacent to the involved bronchi and multifocal involvement of bronchial narrowing may be helpful in differentiating this condition from lung cancer.


6. DOCID:24796 SCORE: 0.0011345803356567
DOCNO: 10208958
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Mutation
QUALIFIER: genetics
QUALIFIER: genetics
AUTHOR: P Weber P
AUTHOR: V Keim V
AUTHOR: K P Zimmer KP
AFFILIATION: University Children's Hospital, CH-4005 Basel, Switzerland.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Archives of disease in childhood.
COUNTRY: ENGLAND
TITLE: Hereditary pancreatitis and mutation of the trypsinogen gene.
PUBDATE: 19990501
Hereditary pancreatitis is a rare form of chronic recurrent pancreatitis. A family, in which 11 members had chronic pancreatitis, five had diabetes, and two had pancreatic cancer, was studied, and hereditary pancreatitis was diagnosed in all patients by demonstrating the mutation in exon 3 of the cationic trypsinogen gene (R117H). The clinical implications of genotypic analysis in hereditary pancreatitis are discussed.


7. DOCID:30318 SCORE: 0.000847456154228685
DOCNO: 16139958
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Apoptosis
QUALIFIER: physiology
QUALIFIER: physiology
QUALIFIER: physiopathology
QUALIFIER: physiology
AUTHOR: Ze-Jun Liu ZJ
AUTHOR: Xin Lu X
AUTHOR: Shan Zhong S
AFFILIATION: Laboratory of International Cooperation, Southwest Hospital, Third Military Medical University, Chongqing 400038, PRC. a65424208@cta.cq.cn
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Biochimica et biophysica acta.
COUNTRY: Netherlands
TITLE: ASPP--Apoptotic specific regulator of p53.
PUBDATE: 20050901
The p53 protein is one of the best-known tumor suppressors. The recently identified ASPP family (apoptosis-stimulating protein of p53) can interfere with the working of p53. Three members of ASPP family are proved to be apoptotic specific regulators of p53. The discovery of ASPP family may answer such questions as "how cells choose to die". Understanding the ASPP status in human cancer will allow us to develop better strategies to treat cancer.


8. DOCID:30342 SCORE: 0.000847456146674817
DOCNO: 16320132
OWNER: NLM
STATUS: In-Data-Review
AUTHOR: Andrew P Byrnes AP
AFFILIATION: Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Rockville, MD 20852, USA. ByrnesA@cber.FDA.gov.
PUBTYPE: Journal Article
JOURNALTITLE: IDrugs : the investigational drugs journal.
COUNTRY: England
TITLE: Challenges and future prospects in gene therapy.
PUBDATE: 20051201
Gene therapy is a promising technique for treating disease through the modification of gene expression. It is currently being tested not only for correcting genetic defects, but also for treating cancer and other acquired diseases. Although this field is still relatively young, evidence for clinical efficacy has been observed and continued progress seems assured, as clinical trials continue to yield insights into how gene therapy can be applied and improvements are made in gene therapy tools.


9. DOCID:30279 SCORE: 0.000845997030857589
DOCNO: 14755893
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: metabolism
QUALIFIER: therapeutic use
QUALIFIER: metabolism
QUALIFIER: therapeutic use
QUALIFIER: metabolism
QUALIFIER: therapeutic use
QUALIFIER: metabolism
AUTHOR: Michael L Salgaller ML
AFFILIATION: Toucan Capital Corp, 7600 Wisconsin Ave, 7th Floor, Bethesda, MD 20814, USA. msalgaller@toucancapital.com
PUBTYPE: Evaluation Studies
PUBTYPE: Journal Article
JOURNALTITLE: Current opinion in molecular therapeutics.
COUNTRY: England
TITLE: Technology evaluation: bevacizumab, Genentech/Roche.
PUBDATE: 20031201
Bevacizumab, an antivascular endothelial growth factor monoclonal antibody, is being developed by Genentech and Roche as an anti-angiogenesis therapy for the potential treatment of solid tumors. In June 2003, bevacizumab was granted Fast Track status by the FDA for the potential treatment of first-line colorectal cancer. The antibody is currently in phase III trials for non-small-cell lung, colorectal and breast cancers, and in phase II trials for various other solid tumor types.


10. DOCID:31449 SCORE: 0.000845883594772029
DOCNO: 12063827
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Infusions, Intra-Arterial
QUALIFIER: drug therapy
QUALIFIER: administration & dosage
QUALIFIER: drug therapy
AUTHOR: Matthias Lorenz M
AUTHOR: Stefan Heinrich S
AFFILIATION: Department of General and Vascular Surgery, University Hospital of Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany. M.Lorenz@em.uni-frankfurt.de
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Hematology/oncology clinics of North America.
COUNTRY: United States
TITLE: Regional chemotherapy.
PUBDATE: 20020201
Regional chemotherapy is an interesting treatment option in patients with advanced pancreatic cancer but cannot be considered standard treatment, and it should not be performed outside controlled clinical trials. The real value of regional chemotherapy must be evaluated in larger, randomized trials. New drug combinations may reduce the observed side effects and improve tumor response. Gene therapy with p53 and K-ras modulated herpesviruses may become a palliative treatment option and can be administered easily by regional chemotherapy techniques [23].


11. DOCID:28491 SCORE: 0.000845330192903122
DOCNO: 12413934
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: Nelson Gustavo Neder Kalil NG
AUTHOR: William Patrick McGuire WP
AFFILIATION: Hematology/Oncology Section, Franklin Square Hospital Center, 9000 Franklin Square Drive, Baltimore, Maryland 21237-3998, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Best practice & research. Clinical obstetrics & gynaecology.
COUNTRY: England
TITLE: Chemotherapy for advanced epithelial ovarian carcinoma.
PUBDATE: 20020801
Advanced epithelial ovarian cancer (AOC) is the most common clinical presentation of ovarian cancer. Virtually all patients will require some form of chemotherapy with curative or palliative intent. Prognostic factors, first- and second-line therapy, as well as experimental approaches for AOC are reviewed.


12. DOCID:26958 SCORE: 0.000836473525896896
DOCNO: 10374686
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: secondary
QUALIFIER: pathology
QUALIFIER: secondary
AUTHOR: A Giuliani A
AUTHOR: A Caporale A
AUTHOR: M Di Bari M
AUTHOR: M Demoro M
AUTHOR: P Mingazzini P
AFFILIATION: Istituto I Clinica Chirurgica, Università La Sapienza, Rome, Italy.
PUBTYPE: Journal Article
JOURNALTITLE: Journal of experimental & clinical cancer research : CR.
COUNTRY: ITALY
TITLE: Isolated splenic metastasis from endometrial carcinoma.
PUBDATE: 19990301
Splenic involvement by carcinomatous metastases occurs late in the course of widely disseminated disease. Solitary metastasis to the spleen from a primary of any source is an uncommon event. We report a case of a 58-year-old woman in which an asymptomatic solitary metastatic endometrial adenocarcinoma of the spleen was detected 28 months after resection of the primary malignancy and treated by splenectomy. There are thirteen other reported cases of solitary splenic metastasis from gynecological cancers; in four of these reports the source was endometrial.


13. DOCID:26825 SCORE: 0.000836435085963999
DOCNO: 11380352
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: psychology
QUALIFIER: etiology
AUTHOR: F J Andrews FJ
AFFILIATION: BreastScreen Victoria Inc., Carlton, Victoria, Australia. fionaa@breastscreen.org.au
PUBTYPE: Journal Article
JOURNALTITLE: Australasian radiology.
COUNTRY: Australia
TITLE: Pain during mammography: implications for breast screening programmes.
PUBDATE: 20010501
Pain experienced during mammography can deter women from attending for breast cancer screening. Review of the current literature on pain experienced during mammography reveals three main areas of interest: reports of the frequency of pain, identification of predictors of pain and strategies for responding to pain. Implications of this literature for breast screening programmes include the need for appropriate measurements of pain during mammography that are valid for screening populations, a further understanding of organizational factors involved in screening programmes that may be predictors of pain and for the development of valid strategies for responding to pain within breast screening programmes.


14. DOCID:26957 SCORE: 0.00083641662050984
DOCNO: 10399438
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: ultrastructure
QUALIFIER: pathology
QUALIFIER: ultrastructure
QUALIFIER: ultrastructure
QUALIFIER: ultrastructure
QUALIFIER: ultrastructure
AUTHOR: V I Tsygankov VI
AUTHOR: S I Shvets SI
AUTHOR: G L Mogileva GL
AUTHOR: V M Kindialov VM
AUTHOR: N P Mel'nikova NP
PUBTYPE: Journal Article
JOURNALTITLE: Klinicheskaia laboratornaia diagnostika.
COUNTRY: RUSSIA
TITLE: [The nuclear morphotypes of epithelial cells in breast diseases]
PUBDATE: 19990501
Staining of the nucleolar ribosome organizer with AgNO3 followed by computer analysis of images by discriminant analysis helped distinguish 6 morphological types in the cells of cytological preparations of mammary glands. Comparison of the morphometrical data and results of visual examination of cells showed that the first type included nonproliferating fibroadenoma and mastopathy, type 2 fibroadenoma and mastopathy with moderate proliferation of epithelium, type 3 fibroadenoma and mastopathy with precancer epithelial proliferation, and types 4-6 included malignant proliferating cells which are compatible with well, moderately, and poorly differentiated cancer.