0. DOCID:22852 SCORE: 0.00444774122475374
DOCNO: 7773901
AUTHOR: A Mullens A
PUBTYPE: Journal Article
JOURNALTITLE: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.
COUNTRY: CANADA
TITLE: The Dutch experience with euthanasia: lessons for Canada?
PUBDATE: 19950601
Anne Mullens used a recent fellowship provided by the Atkinson Foundation to take an in-depth look at euthanasia in the Netherlands. During her time in Holland, she discussed the issue with doctors who support and oppose euthanasia. She accompanied a doctor as he visited a patient who was dying of cancer and was beginning to consider the possibility of euthanasia. She talked to a nonphysician who is adamantly opposed to euthanasia and carries a card stating that. She visited a hospital in Amsterdam that has received requests from foreigners seeking euthansia. Mullens offers a comprehensive look at an issue that continues to provoke strong feelings among Canadian physicians and patients.


1. DOCID:22851 SCORE: 0.00444774103293839
DOCNO: 8844291
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Kidney Pelvis
DESCRIPTOR: Neoplasms, Multiple Primary
QUALIFIER: diagnosis
QUALIFIER: diagnosis
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: M Ando M
AUTHOR: C Arisawa C
AUTHOR: T Okano T
AFFILIATION: Department of Urology, East Tokyo Metropolitan Hospital, Japan.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: International journal of urology : official journal of the Japanese Urological Association.
COUNTRY: JAPAN
TITLE: A case of renal cell carcinoma associated with synchronous contralateral renal pelvic cancer and bladder tumor.
PUBDATE: 19960701
We report a case of renal cell carcinoma associated with synchronous contralateral renal pelvic cancer and bladder tumor. The patient underwent total nephroureterectomy for the left renal pelvic cancer with transurethral resection of the bladder tumor. After 2 courses of combination chemotherapy, we performed surgical enucleation of the right renal cell carcinoma. Although transurethral resection of the recurrent bladder tumors was undergone 17 months after the last operation, the patient retains normal renal function.


2. DOCID:22825 SCORE: 0.00444774065645133
DOCNO: 7774494
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: analysis
AUTHOR: A W Martin AW
AUTHOR: D D Davey DD
AFFILIATION: Department of Pathology, University of Louisville School of Medicine, KY, USA.
PUBTYPE: Journal Article
JOURNALTITLE: Diagnostic cytopathology.
COUNTRY: UNITED STATES
TITLE: Comparison of immunoreactivity of neu oncoprotein in fine-needle aspirates and paraffin-embedded materials.
PUBDATE: 19950301
Expression of the neu oncogene has been extensively examined in frozen and paraffin section breast cancers; however, very few studies examine neu oncoprotein oncoprotein expression in fine-needle aspirates. To this effect, we compared the expression of neu oncoprotein in formalin-fixed paraffin-embedded breast cancers and the corresponding fine-needle aspirates of these cancers. There was 100% correlation between the expression of neu oncoprotein in the paraffin-embedded breast cancers and the fine-needle aspirates, indicating the suitability of fine-needle aspirates for the expression of neu oncoprotein in breast cancers.


3. DOCID:7094 SCORE: 0.00427210155117307
DOCNO: 7008297
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: epidemiology
QUALIFIER: analysis
QUALIFIER: immunology
QUALIFIER: epidemiology
AUTHOR: L Dominioni L
AUTHOR: R Dionigi R
AUTHOR: M Campani M
PUBTYPE: Journal Article
JOURNALTITLE: Tumori.
COUNTRY: ITALY
TITLE: Postoperative infections and variations of complement components in cancer patients.
PUBDATE: 19801001
Sequential determinations of C4 and factor B serum levels were performed pre- and postoperatively in 56 cancer patients. Patients who underwent radical mastectomy and excision of melanoma had an incidence of surgical infections of 7% and 15%, respectively, and showed a significant postoperative acute-phase increase of C4 and factor B serum levels. A higher incidence of postoperative infections, mostly Gram negative, was recorded in patients who underwent gastric resection (35%) and colorectal resection (73%); these failed to show an early acute-phase response of complement postoperatively. The results of this study confirm the high susceptibility of cancer patients to postoperative infections. Moreover, the lack of postoperative acute-phase increase of C4 and factor B observed in cancer patients who developed postoperative infections suggests an active role of complement in host defense mechanisms against surgical infections.


4. DOCID:7136 SCORE: 0.00427210140582518
DOCNO: 75080
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Cryosurgery
QUALIFIER: surgery
AUTHOR: A A Gage AA
PUBTYPE: Journal Article
JOURNALTITLE: Comprehensive therapy.
COUNTRY: UNITED STATES
TITLE: Cryosurgery for cancer.
PUBDATE: 19780201
Cryosurgery has a wide range of uses for the destruction of tumours. Acceptability among dermatologists for the treatment of skin cancer appears high. In the treatment of oral cancer, cryosurgery is not yet widely accepted, but it should be more commonly used for early cancer and in the management of selected problems in therapy. It has established a reasonably firm place in the treatment of prostatic cancer, perhaps because of continued interest in the immunologic benefits, while its use in gynecologic organs is limited to carcinoma in situ or to selected patients with advanced cancer. In all these areas, it has been used with surprisingly good results in selected patients who were high risks under conventional methods of therapy. The trial of cryosurgery in the treatment of bone tumors should prove its efficacy. Today's interest in cryosurgery is consistent with the current trend to conservatism in cancer surgery.


5. DOCID:1773 SCORE: 0.00258117119380698
DOCNO: 1159922
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Prostatectomy
QUALIFIER: surgery
AUTHOR: F H Schroeder FH
AUTHOR: E Belt E
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of urology.
COUNTRY: UNITED STATES
TITLE: Carcinoma of the prostate: a study of 213 patients with stage C tumors treated by total perineal prostatectomy.
PUBDATE: 19750801
The effects of age, histological grade and clinical extension of carcinoma of the prostate are analyzed in a series of 213 patients with stage C carcinomas treated by total perineal prostatectomy. Survival data and the incidence of local recurrence, distant metastases and deaths from cancer of the prostate are the parameters used for comparison with 132 stage B patients, 70 patients with seminal vesicle invasion and data from the literature. Long-term survivors in the young age group and some long-term survivors with high grade lesions are good arguments for the possible curability of early stage C carcinoma of the prostate by total prostatectomy. Correct surgical staging of these tumors by previous pelvic lymphadenectomy is mandatory.


6. DOCID:16526 SCORE: 0.00235300205238636
DOCNO: 2021690
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Genetic Counseling
QUALIFIER: genetics
AUTHOR: J Feingold J
AFFILIATION: Unité d'epidémiologie génétique, INSERM unité 155, université Paris-VII, France.
PUBTYPE: Journal Article
JOURNALTITLE: Bulletin du cancer.
COUNTRY: FRANCE
TITLE: [Genetic counseling in cancerology]
PUBDATE: 19910101
The evidence that genetic factors are of some importance in the etiology of cancer originates has been determined by genetic epidemiology, molecular biology, cytogenetics. Genetic counselling is one of the possible strategies for controlling cancer through genetics. Genetic counselling in this field more often concerns the family of the affected individual than the individual himself. Its aim is to develop a family oriented preventive medicine.


7. DOCID:15983 SCORE: 0.00215564195289607
DOCNO: 3495421
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Immunization, Passive
QUALIFIER: therapy
QUALIFIER: therapeutic use
QUALIFIER: transplantation
QUALIFIER: therapy
AUTHOR: Z H Wang ZH
AUTHOR: X B Li XB
AUTHOR: X D Yao XD
AUTHOR: D N Ba DN
PUBTYPE: Journal Article
JOURNALTITLE: Zhonghua zhong liu za zhi [Chinese journal of oncology].
COUNTRY: CHINA
TITLE: [Antimetastasis effect of lymphokine-activated killer (LAK) cells on fibrosarcoma in WKA rats]
PUBDATE: 19861101
Treating WKA rats with fibrosarcoma with LAK cells, antimetastasis effect was studied. The results indicated that splenocytes incubated by IL-2 could produce lytic activity to WKA rats with fibrosarcoma in vitro. Passive infusion of LAK cells lead to a marked reduction in the number of metastatic nodules in the lung. After intravenous injection of LAK cells, cancer cells in the lung speedily disappeared. LAK cell administration for 3 times gave better result than once only (P less than 0.01). In this paper, the possibility of LAK cells used as an adoptive immunotherapy for human neoplasms is briefly discussed.


8. DOCID:9952 SCORE: 0.00204403443166534
DOCNO: 6865687
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Preoperative Care
QUALIFIER: radiation effects
QUALIFIER: therapy
AUTHOR: A I Popov AI
PUBTYPE: Journal Article
JOURNALTITLE: Meditsinskaia radiologiia.
COUNTRY: USSR
TITLE: [Effect of preoperative radiation therapy on intravascular blood coagulation in the combined treatment of kidney cancer patients]
PUBDATE: 19830601
Hemostasis has been studied over time in 137 patients with renal cancer. Of these, 69 underwent surgery only, 68 received combined treatment with preoperative large fractionation radiotherapy. It has been established that renal cancer development in the body stimulates intravascular blood coagulation (IVBC). In the patients with renal cancer who were radiation treated, IVBC activation was more noticeable than in those who had surgery only. To prevent IVBC activation and the development of the DIVC-syndrome, it is proposed to prescribe deaggregates in the period of preoperative therapy and heparin in the postoperative period.


9. DOCID:3839 SCORE: 0.00197575557145546
DOCNO: 1028554
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
PUBTYPE: Journal Article
JOURNALTITLE: Consumer reports.
COUNTRY: UNITED STATES
TITLE: Estrogen therapy: the dangerous road to Shangri-La.
PUBDATE: 19761101
The use of estrogens almost tripled during the 1965-75 period, with usage concentrated as a cure-all for aging, for the degenerative diseases associated with aging, and for the emotional difficulties of middle age. 3 separate studies published in the last year have shown a high level of association between estrogen use and the development of endometrial cancer. Results of these studies coupled with the significant recent increase in the incidence of cancer in women over 50 who are in the high socioeconomic groups--the groups most likely to use estrogen therapy--emphasize the association. The U.S. FDA has proposed a modification in the labeling for estrogens, and a package insert for patients which would warn of possible hazards of estrogen therapy. It is recommended that estrogen be used only for vasomotor symptoms and vaginal atrophy. The lowest possible effective dosage should be used and for the shortest possible amount of time. Earlier studies had suggested that estrogen replacement therapy might protect against breast cancer; most recent studies suggest the opposite. In addition, estrogen may trigger high blood pressure and increase some blood clotting. Women with high blood pressure or a family history of early heart attacks are contraindicated from using estrogen therapy. Even for the treatment of osteoporosis, there may be safer alternative therapies. Women are cautioned as to their own responsibilities when taking estrogens.


10. DOCID:2394 SCORE: 0.00196296897813452
DOCNO: 1258933
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: chemically induced
AUTHOR: H K Ziel HK
AUTHOR: W D Finkle WD
PUBTYPE: Journal Article
JOURNALTITLE: American journal of obstetrics and gynecology.
COUNTRY: UNITED STATES
TITLE: Association of estrone with the development of endometrial carcinoma.
PUBDATE: 19760401
Although few clinicians suspect estrogen as the prime cause of endometrial carcinoma, a retrospective study showed the following among postmenopausal women: 70 per cent of those with endometrial carcinoma and only 23 per cent of matched control subjects used estrogen systemically. Endometrial cancer developed an average of five years earlier in those taking than in those not receiving estrogen. Forty-two per cent of those with endometrial cancer had received estrogen three years or more. Most significantly, conjugated estrogens were used by 89 per cent of postmenopausal cancer patients who had received any estrogenic substance. The increased risk of endometrial cancer for all patients receiving conjugated estrogen (the risk ratio) was 7.4. This risk ratio increased with duration of conjugated estrogen exposure, from 4.6 in patients with less than three years' exposure to 9.2 in patients with three or more years' exposure.


11. DOCID:21442 SCORE: 0.00192337548484798
DOCNO: 8854414
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Mass Screening
DESCRIPTOR: Patient Education
QUALIFIER: prevention & control
AUTHOR: A Boyden A
AFFILIATION: Public Health Branch, Dept. of Human Services, Victoria.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Australian family physician.
COUNTRY: AUSTRALIA
TITLE: Prostate cancer screening: what general practitioners and patients need to know.
PUBDATE: 19960901
Much controversy surrounds the appropriateness of screening for prostate cancer. The individual benefit from screening is unproven. Screening may result in many men being unnecessarily treated for prostate cancer with the associated risks of developing treatment related side effects, including impotence and incontinence. Men requesting screening need to be informed of these issues before they decide whether to proceed. This article reviews the current position in relation to screening, critically appraising current thinking in order to clarify the issues.


12. DOCID:24375 SCORE: 0.00173444107128832
DOCNO: 10373991
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: therapeutic use
QUALIFIER: therapy
QUALIFIER: therapy
AUTHOR: L K Swibold LK
AFFILIATION: Veterans Affairs Medical Center, Tucson, AZ, USA.
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
JOURNALTITLE: Urologic nursing : official journal of the American Urological Association Allied.
COUNTRY: UNITED STATES
TITLE: Maintenance therapy with bacillus Calmette-Guerin in patients with superficial bladder cancer.
PUBDATE: 19990301
The effectiveness of intravesical therapy with bacillus Calmette-Guerin for the treatment of superficial bladder cancer has been well established. However, there is no consensus about the optimum regimen for administering BCG. Maintenance therapy in 28 patients, results, and complications are addressed.


13. DOCID:22400 SCORE: 0.00171176344735501
DOCNO: 7529813
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Home Care Services
DESCRIPTOR: Palliative Care
QUALIFIER: therapeutic use
QUALIFIER: complications
QUALIFIER: drug therapy
QUALIFIER: complications
AUTHOR: S Mercadante S
AUTHOR: M T Simonetti MT
AFFILIATION: Department of Anesthesia and Intensive Care, Buccheri La Ferla Fatebenefratelli Hospital, Palermo, Italy.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Journal of pain and symptom management.
COUNTRY: UNITED STATES
TITLE: Dobutamine as palliative drug in home-care advanced cancer patients.
PUBDATE: 19941001
We describe a patient with advanced cancer whose severe symptoms of congestive heart failure were successfully treated with dobutamine. The intermittent intravenous administration of dobutamine 5 micrograms/kg/min for 3 hr per day at home enabled control of dyspnea, leg edema, and pain, and increased urine output after 1 day. An improvement in renal function was observed in the following days. The mechanism and the utility of a palliative approach with dobutamine are discussed.


14. DOCID:6892 SCORE: 0.00170947391268785
DOCNO: 556273
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Tendons
QUALIFIER: pathology
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: T O Ekfors TO
AUTHOR: V Rantakokko V
PUBTYPE: Journal Article
JOURNALTITLE: Pathology, research and practice.
COUNTRY: GERMANY, WEST
TITLE: Clear cell sarcoma of tendons and aponeuroses: malignant melanoma of soft tissues? Report of four cases.
PUBDATE: 19791201
In a survey of 246 soft tissue sarcomas in the extremities and limb girdles reported to the Finnish Cancer Registry in 1960-1969, two clear cell sarcomas of tendons and aponeurones were diagnosed. We subsequently diagnosed two more examples. Three tumors were located in the foot and one in the wrist. The histology of the tumors was characteristic, and three of them were shown to contain brown pigment tinctorially indistinguishable from melanin. The pigment could be bleached with potassium permanganate. Ultrastructural studies performed in the most recent case revealed premelanosomes in the cytoplasm of tumor cells. Increasing evidence in the literature and results of the present study seem to suggest that clear cell sarcoma of tendons and aponeuroses represents a soft tissue malignant melanoma.