0. DOCID:10689 SCORE: 0.00312306414108581
DOCNO: 6607823
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Sigmoidoscopy
QUALIFIER: diagnosis
QUALIFIER: utilization
QUALIFIER: diagnosis
AUTHOR: J Rosevelt J
AUTHOR: H Frankl H
PUBTYPE: Journal Article
JOURNALTITLE: Digestive diseases and sciences.
COUNTRY: UNITED STATES
TITLE: Colorectal cancer screening by nurse practitioner using 60-cm flexible fiberoptic sigmoidoscope.
PUBDATE: 19840201
In a routine sigmoidoscopy clinic a specially trained nurse practitioner examined 825 patients between the ages of 23 and 88 with a mean age of 59. Seventy-two patients were found to have polyps; only eight of these patients had a history of rectal bleeding. Seventy-nine percent of these polyps were above 25 cm or beyond the reach of the rigid scope. Three patients with polyps were found to have cancer in the polyp. None of these patients had noted rectal bleeding. Significantly, there was a 10.6% yield of positive pathology among patients 50 and over. The training of the nurse practitioner is described in the article.

1. DOCID:11463 SCORE: 0.00292325353632035
DOCNO: 6689385
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
QUALIFIER: therapy
AUTHOR: M Fazio M
AUTHOR: F Badellino F
AUTHOR: G L Sannazzari GL
AUTHOR: V Vercellino V
AUTHOR: M Airoldi M
AUTHOR: A Manca A
AUTHOR: S Gandolfo S
PUBTYPE: Journal Article
JOURNALTITLE: Tumori.
COUNTRY: ITALY
TITLE: Oral and pharyngeal cancer: combined approach for multimodal therapy.
PUBDATE: 19831201
Five-year results in 60 oral and pharyngeal cancer patients treated with combined approach chemoradiotherapy (39 patients) and chemoradiotherapy plus lymph node surgery (21 patients) are reported. Complete remission (CR) was achieved in 16/39 (41%) patients treated with chemoradiotherapy alone, and in 16/21 (76%) patients who had chemoradiotherapy plus surgery. The number of CR was statistically (chi-square test) higher (p less than 0.025) in the second group. The 5-year actuarial survival was 39.7% in the group of patients treated with chemoradiotherapy plus surgery. After 5 years 53% of the patients who reached CR are living free of disease in the first group and 76% in the second group.

2. DOCID:11129 SCORE: 0.00262563261806315
DOCNO: 4053659
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Tomography, X-Ray Computed
QUALIFIER: radiography
AUTHOR: K Chintapalli K
AUTHOR: M K Thorsen MK
AUTHOR: T L Lawson TL
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of computed tomography.
COUNTRY: UNITED STATES
TITLE: Differential diagnosis of low-attenuation splenic lesions on computed tomography.
PUBDATE: 19851001
A retrospective computed tomography evaluation of proved low-attenuation splenic lesions in nontraumatic cases was done. Computed tomography was able to distinguish cystic from solid lesions. Although computed tomography examination is sensitive in the detection of low-attenuation lesions, the computed tomography findings alone are not helpful in differentiation of different low-attenuation lesions. Associated computed tomography findings in other organs and clinical findings are more helpful than the size, shape, and computed tomography attenuation of the lesions. Splenic lesions may be the only metastatic manifestation in some cancer patients. A thin needle aspiration may be done to document the nature of the pathologic lesion in problematic cases.

3. DOCID:10278 SCORE: 0.00253288591891213
DOCNO: 2579498
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
AUTHOR: N Green N
AUTHOR: H Bodner H
AUTHOR: E Broth E
PUBTYPE: Journal Article
JOURNALTITLE: Urology.
COUNTRY: UNITED STATES
TITLE: Prostate cancer: experience with definitive irradiation in the aged.
PUBDATE: 19850301
When considering therapeutic options for localized prostate cancer, stage and grade of disease have been the most important determinants. In the elderly, the nominal age has assumed increasing importance in the final decision. A balanced judgment must be reached between the patient's normal life expectancy and the rapidity with which the cancer may be expected to express its malignant potential. By careful attention to patient selection and the details of treatment, definitive irradiation can improve quality of life and survival. Of 63 patients aged seventy-three to ninety years referred for irradiation, 56 were found medically suitable for definitive treatment. A review of our experience is presented.

4. DOCID:11958 SCORE: 0.00252939562495294
DOCNO: 6149198
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Prenatal Exposure Delayed Effects
QUALIFIER: etiology
QUALIFIER: etiology
AUTHOR: R H Depue RH
PUBTYPE: Journal Article
JOURNALTITLE: International journal of epidemiology.
COUNTRY: ENGLAND
TITLE: Maternal and gestational factors affecting the risk of cryptorchidism and inguinal hernia.
PUBDATE: 19840901
Case-control studies of cryptorchidism and inguinal hernia were undertaken on white males born within the cohort of the Collaborative Perinatal Project of the National Institute of Neurological and Communicative Disorders and Stroke. Significantly elevated risks of cryptorchidism were found for low birthweight, for a high maternal Quetelet's index and for oestrogens administered during gestation (R = 2.8). Similarly, in the case of inguinal hernia, significantly increased risk ratios were observed for low birthweight, for gestational use of progestins (RR = 2.1), and for breech labour (RR = 2.3). Because these malformations and testis cancer share many of the same risk factors, a common mechanism for production of these diseases is proposed which is mediated by testicular hypoplasia induced by excess exogenous or endogenous oestrogen in the mother.

5. DOCID:11219 SCORE: 0.0024872102826451
DOCNO: 6697332
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug effects
QUALIFIER: drug therapy
AUTHOR: E Cadman E
AUTHOR: C Benz C
PUBTYPE: Journal Article
JOURNALTITLE: Cancer treatment reports.
COUNTRY: UNITED STATES
TITLE: Cytotoxicity of several chemotherapeutic agents in a human pancreatic cancer cell line (Colo-357).
PUBDATE: 19840201
Seven commonly available chemotherapeutic drugs were used to determine the concentration and time of exposure necessary to kill the newly available human pancreatic cancer cell line, Colo-357. The exposure periods were 2, 6, 12, and 24 hours. The most active drugs were methotrexate, mitomycin, and doxorubicin, each with an ID50 less than 0.1 microM for both a 12- and a 24-hour exposure. Cisplatin was intermediate, with an ID50 of approximately 0.7 microM at 12 and 24 hours. 5-FU, carmustine, and streptozocin were the least effective agents, with ID50 values greater than 50 microM after a 12-hour exposure and greater than 25 microM after a 24-hour exposure.

6. DOCID:11203 SCORE: 0.00238782384419237
DOCNO: 3982252
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiation effects
QUALIFIER: adverse effects
QUALIFIER: therapeutic use
QUALIFIER: prevention & control
QUALIFIER: therapeutic use
QUALIFIER: radiation effects
QUALIFIER: radiotherapy
AUTHOR: G M Zharinov GM
AUTHOR: S F Vershinina SF
AUTHOR: O I Dran'kova OI
PUBTYPE: Journal Article
JOURNALTITLE: Meditsinskaia radiologiia.
COUNTRY: USSR
TITLE: [Prevention of radiation damage to the bladder and rectum using local application of dimethyl sulfoxide]
PUBDATE: 19850301
A method for the prevention of radiation injuries of the urinary bladder and rectum for cervical cancer patients was worked out. It was based on the local application of the radioprotective agent dimethylsulfoxide (DMSO) before a session of interstitial irradiation with the AGAT-B apparatus. Concomitant radiation therapy with DMSO was provided to 22 cervical cancer patients. The control group included 59 patients who received similar treatment without DMSO. The expression of early reactions and late injuries of the rectum and urinary bladder were significantly lower in the DMSO group. A radioprotective DMSO effect with relation to tumor was not found.

7. DOCID:10482 SCORE: 0.00236445792555733
DOCNO: 6373856
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: genetics
QUALIFIER: genetics
QUALIFIER: genetics
QUALIFIER: genetics
AUTHOR: L Banse-Kupin L
AUTHOR: A Morales A
AUTHOR: M Barlow M
PUBTYPE: Case Reports
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Journal of the American Academy of Dermatology.
COUNTRY: UNITED STATES
TITLE: Torre's syndrome: report of two cases and review of the literature.
PUBDATE: 19840501
Two patients with multiple sebaceous adenomas associated with visceral carcinoma (Torre's syndrome) are described, and reported cases in the literature are summarized. Certain aspects of Torre's syndrome are emphasized: that the presence of multiple sebaceous adenomas is a cutaneous marker for visceral carcinomas, that the associated carcinomas are of comparatively low-grade malignancy, and that it is a genetic condition probably related to the Cancer Family syndrome. In addition, three morphologic patterns of the sebaceous adenoma are described: solid, cystic, and "keratoacanthoma-like"; then, the potential pitfalls in the histopathologic interpretation of this tumor are discussed.

8. DOCID:10523 SCORE: 0.00236445760796432
DOCNO: 6205336
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: secondary
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: F Beaufort F
AUTHOR: M Gölles M
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
PUBTYPE: Randomized Controlled Trial
JOURNALTITLE: Onkologie.
COUNTRY: SWITZERLAND
TITLE: [Calcitonin in bone-metastasizing breast carcinoma. Results of a pilot study]
PUBDATE: 19840601
48 patients with metastatic breast cancer and extensive bone involvement were treated with salm-calcitonin and polychemo-therapy or hormonal treatment. They were compared with a control group of 73 patients without calcitonin therapy. One third of the patients from the calcitonin group referred pain relief which was obviously independent from the therapy effects of the polychemo or hormonal treatment. Since only subjective criteria for sceletal pains were used and no therapy arm with calcitonin alone was studied, the results of our study have to be critically analyzed together with other reports about calcitonin and bone metastases in the literature.

9. DOCID:11413 SCORE: 0.0023554091567548
DOCNO: 7063854
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Aging
DESCRIPTOR: Diet
QUALIFIER: epidemiology
AUTHOR: R Weindruch R
AUTHOR: R L Walford RL
PUBTYPE: Journal Article
JOURNALTITLE: Science.
COUNTRY: UNITED STATES
TITLE: Dietary restriction in mice beginning at 1 year of age: effect on life-span and spontaneous cancer incidence.
PUBDATE: 19820301
Lifelong dietary restriction beginning at 3 to 6 weeks of age in rodents is known to decelerate the rate of aging, increase mean and maximum life-spans, and inhibit the occurrence of many spontaneous cancers. Little is known about the effects of dietary restriction started in middle age. In the experiments now reported the food intake of 12- to 13-month-old mice of two long-lived strains was restricted by using nutrient-enriched diets in accordance with the concept of "undernutrition without malnutrition." The mice on the restricted diet averaged 10 to 20 percent increases in mean and maximum survival times compared to the control mice. Spontaneous lymphoma was inhibited by the food restriction.

10. DOCID:11279 SCORE: 0.00226153211083095
DOCNO: 6462573
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: D M Luesley DM
AUTHOR: K K Chan KK
AUTHOR: J W Fielding JW
AUTHOR: R Hurlow R
AUTHOR: G R Blackledge GR
AUTHOR: J A Jordon JA
PUBTYPE: Journal Article
JOURNALTITLE: Obstetrics and gynecology.
COUNTRY: UNITED STATES
TITLE: Second-look laparotomy in the management of epithelial ovarian carcinoma: an evaluation of fifty cases.
PUBDATE: 19840901
Fifty patients with ovarian cancer had a second-look laparotomy performed after chemotherapy. Complete histologic response was confirmed in 12 patients, microscopic disease was found in 12 patients, and macroscopic disease was found in 26 patients. Fifteen patients with macroscopic disease had total tumor clearance at second look. Surgical response to chemotherapy was found to correlate well with disease volume at the onset of chemotherapy. The operation is a safe, accurate technique for assessing the ovarian cancer patient. The findings and outcome probably depend upon the timing of the procedure. Any survival benefit from the operation remains to be proved.

11. DOCID:11124 SCORE: 0.00224730001504753
DOCNO: 3843683
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Hysterectomy
QUALIFIER: surgery
AUTHOR: C B Travis CB
PUBTYPE: Journal Article
JOURNALTITLE: Risk analysis : an official publication of the Society for Risk Analysis.
COUNTRY: UNITED STATES
TITLE: Medical decision making and elective surgery: the case of hysterectomy.
PUBDATE: 19850901
Review and analyses of three sources of data are presented indicating that 25% of hysterectomies are elective. Annual mortality associated with elective hysterectomy is estimated to be 319, or about 12,122 woman years. Cost-benefit analyses of mortality, life expectancy, morbidity, psychological sequelae, as well as dollar expenditures, reveal high costs and relatively limited benefits. Explanations for this apparent anomaly in decision making are explored and include economic incentives, system structure, sexism, and cancer prophylaxis. Principles of risk perception are discussed in terms of potential biases associated with the cancer prophylaxis motive. It is suggested that physicians' judgements of risk may be more salient to the decision process than those of prospective patients.

12. DOCID:10200 SCORE: 0.00224399714491719
DOCNO: 3967183
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Smoking
QUALIFIER: etiology
AUTHOR: P Hartge P
AUTHOR: R Hoover R
AUTHOR: A Kantor A
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Bladder cancer risk and pipes, cigars, and smokeless tobacco.
PUBDATE: 19850201
Interview data from 2982 patients with bladder cancer and 5782 controls selected from the general population were used to assess the effects of non-cigarette tobacco use on bladder cancer risk. Compared to men who had never smoked, those who had smoked pipes but not cigars or cigarettes had a relative risk estimated at 1.23 (95% confidence interval [CI] = 0.75-2.00). Those who smoked cigars but not pipes or cigarettes were estimated to have a relative risk of 1.33 (95% CI = 0.92-1.94). Little evidence of dose response was observed. The excess relative risk to pipe smokers was limited to those who inhaled deeply.

13. DOCID:10231 SCORE: 0.0022177339754676
DOCNO: 6618707
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Alcohol Drinking
DESCRIPTOR: Smoking
QUALIFIER: etiology
AUTHOR: A J Tuyns AJ
PUBTYPE: Journal Article
JOURNALTITLE: International journal of cancer. Journal international du cancer.
COUNTRY: DENMARK
TITLE: Oesophageal cancer in non-smoking drinkers and in non-drinking smokers.
PUBDATE: 19831001
Alcohol and tobacco are the two major risk factors for cancer of the oesophagus; they usually combine their action. The action of each factor is studied here in non-users of the other. Among non-drinking male smokers the relative risk is higher than 5; among non-smoking drinkers, risks are much higher and increase with average daily intake; this effect is also observed in females, with risk values of the same order of magnitude as for males. Thus the high sex ratio of oesophageal cancer in France can be entirely ascribed to different drinking levels in females and in males.

14. DOCID:9737 SCORE: 0.00221423914069001
DOCNO: 6836163
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Adaptation, Psychological
QUALIFIER: rehabilitation
QUALIFIER: methods
AUTHOR: P Herschbach P
PUBTYPE: Journal Article
JOURNALTITLE: Die Rehabilitation.
COUNTRY: GERMANY, WEST
TITLE: [Psychosocial rehabilitation of cancer patients]
PUBDATE: 19830201
The author draws attention of three myths that seem to be establishing in the framework of psychosocial rehabilitation of cancer patients, i.e. - that our current knowledge of the psychosocial situation of cancer patients is sufficient to enable systematic therapies to be offered; - that our current knowledge allows coping processes in cancer patients to be evaluated; - that disease models stemming from the treatment of neuroses can be transferred to psychotherapy of cancer patients. The potentially adverse implications these doctrines have for practical therapeutic work are underlined, and proposals are put forward relative to the fundamental research needed in the field of psychotherapy of cancer patients.