0. DOCID:30937 SCORE: 0.00262326805587226
DOCNO: 15508437
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Laparoscopy
QUALIFIER: methods
QUALIFIER: surgery
AUTHOR: Yutaka Kawamura Y
AUTHOR: Fumio Konishi F
AFFILIATION: Dept. of Surgery, Omiya Medical Center, Jichi Medical School, Saitama, Japan.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: Japan
TITLE: [Colorectal cancer]
PUBDATE: 20041001
Laparoscopic surgery for the cure of colorectal cancer has been a controversial issue. In this article summarizes the surgical procedures for right-and left-sided colon cancer as well as the results of randomized controlled trials (RCTs) while comparing the long-term results of laparoscopic and open surgery. The RCTs revealed no significant differences in overall survival rate between laparoscopic and open procedures. In future, laparoscopic surgery will be a standard operation for a certain group of patients with colorectal cancer. Adequate skills of the surgical team and appropriate patient selection are essential.


1. DOCID:31088 SCORE: 0.00246842095184604
DOCNO: 15119470
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: epidemiology
AUTHOR: Ghada N Radwan GN
AUTHOR: Mostafa K Mohamed MK
AUTHOR: Maged El-Setouhy M
AUTHOR: Ebenezer Israel E
AFFILIATION: Egyptian Smoking Prevention Research Institute.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Journal of the Egyptian Society of Parasitology.
COUNTRY: Egypt
TITLE: Review on water pipe smoking.
PUBDATE: 20031201
Water-pipe smoking may lead to cancers, genetic damage, diseases of the lungs and other disease conditions. Many of the studies on these subjects are merely anecdotal or lack the necessary rigorous study design or the power needed to be certain of the results. Given the large number of people who smoke waterpipe and the fact that waterpipe smoking has become a fashionable trend in the Middle East and the Western world among the youth, it is essential to study the health effects of waterpipe smoking with renewed emphasis.


2. DOCID:31301 SCORE: 0.0024074704844939
DOCNO: 12575893
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Perioperative Care
QUALIFIER: surgery
AUTHOR: Ellen F Manzullo EF
AUTHOR: Harrison G Weed HG
AFFILIATION: Department of General Internal Medicine, Ambulatory Treatment, and Emergency Care, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Box 437, Houston, TX 77030, USA. emanzull@mdanderson.org
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The Medical clinics of North America.
COUNTRY: United States
TITLE: Perioperative issues in patients with cancer.
PUBDATE: 20030101
The perioperative care of patients with cancer can be an exciting challenge. The physician must consider many factors, including the cancer diagnosis, the extent of disease, treatment received, the presence of comorbid conditions, and the patient's prognosis and must understand the impact of these factors on the planned surgical procedure. In this setting, the physician has the opportunity to perform an essential role in the perioperative management of patients with cancer.


3. DOCID:31489 SCORE: 0.00238412602667079
DOCNO: 15993613
OWNER: NLM
STATUS: In-Process
AUTHOR: Cheng-Lin Lee CL
AUTHOR: Chi-Fong Lin CF
AUTHOR: Wan-Ru Lin WR
AUTHOR: Kun-Sheng Wang KS
AUTHOR: Ya-Her Chang YH
AUTHOR: Shinne-Ren Lin SR
AUTHOR: Yang-Chang Wu YC
AUTHOR: Ming-Jung Wu MJ
AFFILIATION: Faculty of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung, Taiwan.
PUBTYPE: Journal Article
JOURNALTITLE: Bioorganic & medicinal chemistry.
COUNTRY: England
TITLE: Design, syntheses, and biological evaluations of squamostolide and its related analogs.
PUBDATE: 20051001
Squamostolide and its related analogs were designed and synthesized for biological evaluation. All these compounds were tested for growth inhibition activities against human tumor cell lines, in which one of the compounds showed the most potent cytotoxicity among these derivatives against a full panel of 60 human cancer cell lines. The same compound also showed G2/M phase arrest and a weak apoptotic effect during flow cytometric analysis.


4. DOCID:30526 SCORE: 0.00237111151303077
DOCNO: 12892510
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: methods
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
QUALIFIER: drug therapy
AUTHOR: C A Kendall CA
AUTHOR: C A Morton CA
AFFILIATION: Cranfield Postgraduate Medical School, Gloucestershire Royal Hospital, Great Western Road, Gloucester GL1 3NN, UK. c.kendall@medical-research-centre.com
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Technology in cancer research & treatment.
COUNTRY: United States
TITLE: Photodynamic therapy for the treatment of skin disease.
PUBDATE: 20030801
The efficacy of photodynamic therapy for the treatment of a large number of skin diseases, in particular non-malignant skin cancer, has been reported by a number of studies. It has been demonstrated to be particularly beneficial for large or multiple lesions, especially where good cosmesis is required. However for PDT to become established in routine clinical practice further comparative multi-center studies with currently accepted standard techniques are required.


5. DOCID:31748 SCORE: 0.00236592660531903
DOCNO: 16138976
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: etiology
QUALIFIER: etiology
AUTHOR: Lars Frost L
AUTHOR: Peter Vestergaard P
AFFILIATION: Arhus Universitetshospital, Arhus Sygehus, Medicinsk-kardiologisk Afdeling A. rlg04lfr@as.aaa.dk
PUBTYPE: Journal Article
JOURNALTITLE: Ugeskrift for laeger.
COUNTRY: Denmark
TITLE: [Alcohol consumption and the risk of atrial fibrillation or flutter--secondary publication. A cohort study]
PUBDATE: 20050801
We prospectively examined the association between alcohol consumption and risk of atrial fibrillation or flutter among 47,949 participants (mean age 56 years) in the Danish Diet, Cancer and Health Study. During follow-up (mean 5.7 years) atrial fibrillation or flutter developed in 556 subjects (374 men and 182 women). We found that consumption of alcohol was associated with an increased risk of atrial fibrillation or flutter in men. In women, moderate consumption of alcohol did not seem to be associated with an increased risk of atrial fibrillation or flutter.


6. DOCID:30577 SCORE: 0.00235270413783222
DOCNO: 14650952
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Pyridines
QUALIFIER: pharmacology
QUALIFIER: methods
AUTHOR: Yukimasa Shiotsu Y
AFFILIATION: Pharmaceutical Research Institute, Kyowa Hakko Kogyo Co., Ltd, 1188 Shimotogari, Nagaizumi-cho, Sunto-gun, Shizuoka 411-8731, Japan.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: Japan
TITLE: [Current screening for molecular target therapy of cancer]
PUBDATE: 20031101
Recent progress in molecular biology and cancer biology has revealed that many molecules, which are heavily involved in the un-limited growth, anti-apoptotic effects and invasion of tumors, would be targets of cancer therapy. Part of the drugs which inhibit these molecules have shown clinical response as well as clinical benefits. In this review article, the summary of mechanism based drug screening for cancer as well as recent status of new molecular target drugs for cancer, are described.


7. DOCID:30544 SCORE: 0.00235269934554222
DOCNO: 12722401
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Digestive System Surgical Procedures
QUALIFIER: surgery
AUTHOR: Jarosław Debniak J
AUTHOR: Dagmara Klasa-Mazurkiewicz D
AUTHOR: Maciej Stukan M
AUTHOR: Dariusz Wydra D
AUTHOR: Janusz Emerich J
AFFILIATION: Kliniki Ginekologii, Akademii Medycznej w Gdańsku.
PUBTYPE: Journal Article
JOURNALTITLE: Ginekologia polska.
COUNTRY: Poland
TITLE: [Gastrointestinal surgery in patients with ovarian cancer]
PUBDATE: 20021101
OBJECTIVES: The objectives were to assess indications as well as outcome and morbidity of gastrointestinal surgery in patients with ovarian cancer. METHODS: The study included 74 patients with primary ovarian cancer who had debulking surgery (bowel surgery) from 1987 to 2001. RESULTS: In our group postoperative residual tumor was--R0 in 15 cases (20.3%) and < or = 2 cm (R2) in 33 patients (44.6%). CONCLUSION: Gastrointestinal surgery is frequently indicated during operation in ovarian cancer. Gynecologic cancer surgeons should be trained accordingly.


8. DOCID:31414 SCORE: 0.00232682579078657
DOCNO: 12946629
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Genome
QUALIFIER: metabolism
AUTHOR: Rakesh R Khakhar RR
AUTHOR: Jennifer A Cobb JA
AUTHOR: Lotte Bjergbaek L
AUTHOR: Ian D Hickson ID
AUTHOR: Susan M Gasser SM
AFFILIATION: Cancer Research UK Laboratories, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK OX3 9DS.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Trends in cell biology.
COUNTRY: England
TITLE: RecQ helicases: multiple roles in genome maintenance.
PUBDATE: 20030901
The RecQ helicases are highly conserved in evolution and are required for maintaining genome stability in all organisms. In humans, loss of RecQ helicase function is associated with predisposition to cancer and/or premature ageing. Recent data show that RecQ helicases have several roles during S phase of the cell cycle, ranging from facilitating the resumption of DNA synthesis at sites of replication fork breakdown to resolving structures during the process of homologous recombination.


9. DOCID:30488 SCORE: 0.00231909989140045
DOCNO: 16055020
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pharmacology
QUALIFIER: drug therapy
QUALIFIER: physiopathology
QUALIFIER: antagonists & inhibitors
AUTHOR: Francesco Hofmann F
AUTHOR: Carlos García-Echeverría C
AFFILIATION: Oncology Research, Novartis Institutes for BioMedical Research, Basel, Switzerland. francesco.hofmann@novartis.com
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Drug discovery today.
COUNTRY: England
TITLE: Blocking the insulin-like growth factor-I receptor as a strategy for targeting cancer.
PUBDATE: 20050801
Clear links between cancer and cellular signaling triggered by the insulin-like growth factor-I (IGF-I) receptor (IGF-IR) and its cognate ligands (IGF-I and IGF-II) have been reported throughout the past two decades. Experimental results suggest that the pharmaceutical targeting of this signaling pathway could be beneficial for the treatment of cancer. Here, more recent advances towards potentially clinically viable strategies to interfere with the function of IGF-IR will be discussed.


10. DOCID:30359 SCORE: 0.00226759388955912
DOCNO: 15738898
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: secondary
QUALIFIER: pathology
QUALIFIER: secondary
AUTHOR: Elodie Vauléon E
AUTHOR: Anne-Sophie De Lajarte-Thirouard AS
AUTHOR: Eveline Boucher E
AUTHOR: Elisabeth Le Prisé E
AUTHOR: Patrick Guihaire P
AUTHOR: Jean-Luc Raoul JL
AFFILIATION: Department of Medical Oncology, Comprehensive Cancer Center E. Marquis, CS 44229, 35042 Rennes Cedex, France.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gastroentérologie clinique et biologique.
COUNTRY: France
TITLE: Tonsillar metastasis revealing signet-ring cell carcinoma of the rectum.
PUBDATE: 20050101
A 45-year-old man presented with a tonsillar tumor and rectal syndrome. Histology specimens revealed signet-cell adenocarcinoma of both the tonsils and rectum. The clinical course was rapidly degenerated with multiple metastases in the skin and bones. Tonsil metastasis is rare and generally develops from primary gastric or colorectal cancer, predominantly poorly-differentiated or signet-ring cell adenocarcinomas.


11. DOCID:30743 SCORE: 0.00224048074649663
DOCNO: 14629738
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: metabolism
AUTHOR: Gareth Morgan G
AFFILIATION: National Public Health Service for Wales, 36 Orchard Street, Swansea, U.K. gareth.morgan@nphs.wales.nhs.uk
PUBTYPE: Journal Article
JOURNALTITLE: Pharmacology & toxicology.
COUNTRY: Denmark
TITLE: Should aspirin be used to counteract 'salicylate deficiency'?
PUBDATE: 20031001
Aspirin (acetylsalicylate) is an inexpensive drug that is used extensively to reduce cardiovascular disease risk. Emerging evidence suggests that aspirin reduces the risk of other chronic diseases such as certain forms of cancer. Salicylate may contribute to the disease reduction effects. It is present naturally in fruits and vegetables and individuals with a low intake of these foods may be 'salicylate deficient'. This deleterious state may constitute a significant public health threat. Interventions to prevent deficiency, such as low-dose aspirin programmes, could have substantial beneficial health impacts around the world.


12. DOCID:29433 SCORE: 0.00223325807591294
DOCNO: 14748728
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: chemistry
QUALIFIER: metabolism
QUALIFIER: chemistry
QUALIFIER: metabolism
QUALIFIER: metabolism
AUTHOR: E Ikonen E
AUTHOR: S Heino S
AUTHOR: S Lusa S
AFFILIATION: Institute of Biotechnology, University of Helsinki, 00251 Helsinki, Finland. elina.ikonen@ktl.fi
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Biochemical Society transactions.
COUNTRY: England
TITLE: Caveolins and membrane cholesterol.
PUBDATE: 20040201
Caveolae (small plasma membrane invaginations) and their coat proteins, caveolins, have attracted the attention of researchers in diverse fields, including cell biology, cardiovascular and cancer research. The tight association between caveolin and cholesterol governs the biochemical behaviour of caveolae and is emerging as an important characteristic in a number of processes assigned to these multifunctional organelles. In this review, selected aspects of the caveolin-cholesterol association and its potential functional implications are discussed.


13. DOCID:31652 SCORE: 0.00222536241910159
DOCNO: 15663694
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: secondary
QUALIFIER: pathology
QUALIFIER: secondary
AUTHOR: Ill Young Seo IY
AUTHOR: Sun Gook Kim SG
AUTHOR: Won Cheol Han WC
AUTHOR: Joung Sik Rim JS
AFFILIATION: Department of Urology, Wonkwang University School of Medicine, 344-2 Sinyong-dong, Iksan, Jeonbuk 570-180, Korea. seraph@wonkwang.md
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: International journal of urology : official journal of the Japanese Urological Association.
COUNTRY: Australia
TITLE: Paratesticular mucinous cystadenocarcinoma: metastasis from pancreatic cancer.
PUBDATE: 20041201
We experienced a case of a paratesticular mucinous adenocarcinoma from primary pancreatic cancer. A 67-year old man presented with a scrotal mass. Scrotal ultrasound showed a cystic mass on the testis. Radical orchiectomy was performed and the tumor was revealed as a mucinous cystadenocarcinoma separated from epididymis and testis. Metastatic cancer was suspected and abdominal computed tomography showed pancreatic cancer. We report this rare case of metastatic paratesticular cystoadenocarcinoma.


14. DOCID:31935 SCORE: 0.0022078496610102
DOCNO: 12443768
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Macrolides
QUALIFIER: chemistry
QUALIFIER: pharmacology
QUALIFIER: antagonists & inhibitors
AUTHOR: Yuya Yoshimoto Y
AUTHOR: Takaaki Jyojima T
AUTHOR: Tsuyoshi Arita T
AUTHOR: Minoru Ueda M
AUTHOR: Masaya Imoto M
AUTHOR: Shuichi Matsumura S
AUTHOR: Kazunobu Toshima K
AFFILIATION: Department of Bioscience and Informatics, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan.
PUBTYPE: Journal Article
JOURNALTITLE: Bioorganic & medicinal chemistry letters.
COUNTRY: England
TITLE: Vacuolar-type H(+)-ATPase inhibitory activity of synthetic analogues of the concanamycins: is the hydrogen bond network involving the lactone carbonyl, the hemiacetal hydroxy group, and the C-19 hydroxy group essential for the biological activity of the concanamycins?
PUBDATE: 20021201
Synthetic analogue of the concanamycins, which lacks the hydrogen bond network existing in the concanamycin structure, retains vacuolar-type H(+)-ATPase (V-ATPase) inhibitory activity and induces apoptosis to cancer cells that overexpressing epidermal growth factor receptors (EGFR).