0. DOCID:15319 SCORE: 0.00393714074604043
DOCNO: 2698778
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: secondary
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: J Ishii J
AUTHOR: T Amagasa T
AUTHOR: T Tachibana T
AUTHOR: K Shinozuka K
AUTHOR: S Shioda S
AFFILIATION: First Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Tokyo Medical and Dental University.
PUBTYPE: Journal Article
JOURNALTITLE: The Bulletin of Tokyo Medical and Dental University.
COUNTRY: JAPAN
TITLE: Ultrasonic evaluation of cervical lymph node metastasis of squamous cell carcinoma in oral cavity.
PUBDATE: 19891201
Forty-four patients with oral cancer were examined by ultrasonography to detect cervical lymph nodal metastases. The lymph nodes, which were histopathologically or clinically confirmed to have cancer metastases, showed the following characteristic echogram findings: distinctive nodal boundary, posterior echo enhancement and an increased ratio of the shortest and the longest diameters of the node. It is suggested that these three peculiar ultrasonographic findings are considered to be important items for the differential diagnosis of benign nodes from the cervical metastasis of oral cancer.

1. DOCID:15230 SCORE: 0.00368824332244975
DOCNO: 2427753
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analysis
QUALIFIER: analysis
AUTHOR: K Uehara K
AUTHOR: Y Miyamoto Y
AUTHOR: M Izuo M
AUTHOR: H Shiozaki H
AUTHOR: S Aiba S
AUTHOR: H Matsumoto H
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [Significance of AFP in gastric cancer]
PUBDATE: 19860701
Serum alpha-fetoprotein (AFP) was positive in as few as 5.7-13.5% of gastric cancer patients prior to surgery, and most of the positive cases had cancer of stage IV or higher. Thus, the parameter did not seem to be very useful in diagnosis. It was positive in as many as 45% of terminal cancer patients, while many cases with AFP of more than 1000 ng/ml had metastases to the liver. Thus, AFP was proved to be useful for follow-up of the postoperative course. AFP staining was conducted in 29 dissected stomachs and five of them were positive for AFP staining.

2. DOCID:11702 SCORE: 0.00365036186254935
DOCNO: 6309132
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Terminology
QUALIFIER: classification
QUALIFIER: classification
QUALIFIER: classification
AUTHOR: N C Davis NC
AUTHOR: R C Newland RC
PUBTYPE: Journal Article
JOURNALTITLE: The Australian and New Zealand journal of surgery.
COUNTRY: AUSTRALIA
TITLE: Terminology and classification of colorectal adenocarcinoma: the Australian clinico-pathological staging system.
PUBDATE: 19830601
A new system--the Australian Clinico-pathological Staging (ACPS) System--is proposed for the reporting of cases of colorectal adenocarcinoma. It utilizes all information available--clinical, operative and pathological--before a stage is allotted. This contrasts with Dukes' classification which is based solely on the pathological examination of the resected specimen. The ACPS has a special category 'D' for incurable cancer--those with a locally advanced irremovable tumour or with distant metastases. This method requires co-operation between clinician and pathologist and the use of precise terminology with strict adherence to definitions. The validity of the system is tested by analysing the survival pattern of 709 patients from Concord Hospital according to the ACPS and Dukes' system.

3. DOCID:11151 SCORE: 0.00363533164907347
DOCNO: 6478393
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: methods
QUALIFIER: drug therapy
AUTHOR: J Mäenpää J
AUTHOR: M Grönroos M
AUTHOR: M Leppänen M
AUTHOR: L Kangas L
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: The subrenal capsule assay in mice. Prediction of rat tumor sensitivity to chemotherapy.
PUBDATE: 19841001
The predictive value of the subrenal capsule (SRC) assay for cancer chemotherapy was tested in five rat tumors. Tumor-bearing rats were used as controls. In order to simulate clinical chemotherapy, different dose regimens and drug combinations were used. All five tumors were evaluable in in the SRC assay. Taking into account cytotoxic drugs, 86% compatibility was obtained between the SRC assay and the rat model. Antitumor effect of three antiestrogenic compounds could not be predicted by the SRC assay. It is concluded that the SRC assay can be expected to have predictive value in the assessment of tumor sensitivity to single and combination chemotherapy based on experimental animal models.

4. DOCID:13889 SCORE: 0.00363414505245363
DOCNO: 2476882
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analysis
QUALIFIER: secondary
QUALIFIER: administration & dosage
QUALIFIER: drug therapy
QUALIFIER: blood
AUTHOR: M A Ferro MA
AUTHOR: D Gillatt D
AUTHOR: M O Symes MO
AUTHOR: P J Smith PJ
AFFILIATION: Department of Urology, Bristol Royal Infirmary, United Kingdom.
PUBTYPE: Journal Article
JOURNALTITLE: Urology.
COUNTRY: UNITED STATES
TITLE: High-dose intravenous estrogen therapy in advanced prostatic carcinoma. Use of serum prostate-specific antigen to monitor response.
PUBDATE: 19890901
High-dose intravenous estrogen therapy was shown to be effective in relieving bone pain due to metastatic disease in 22 of 29 (75.9%) men with advanced hormone-resistant prostate cancer. This clinical response was accompanied by significant falls in serum prostate-specific antigen (PSA) levels in 13 (44.8%) patients. It is suggested that this clinical benefit is due to a direct inhibitory effect of estrogen on prostate cancer cells.

5. DOCID:11842 SCORE: 0.00360405692696859
DOCNO: 6322320
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: therapeutic use
QUALIFIER: drug effects
AUTHOR: J L Borgna JL
AUTHOR: H Rochefort H
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: La semaine des hôpitaux : organe fondé par l'Association d'enseignement médical des hôpitaux de Paris.
COUNTRY: FRANCE
TITLE: [Effects and mechanism of action of antiestrogens in breast cancer]
PUBDATE: 19840301
Tamoxifen, a non-steroidal antiestrogen, is currently used to treat post-menopausal breast cancer. In estrogen-sensitive breast cancer cell lines, tamoxifen and some of its metabolites display, for the induction of estrogen-regulated proteins, a partial agonist/antagonist activity. They also inhibit totally the proliferation of these cells. Evidence is given, which suggests that the pharmacological properties of these antiestrogens are mediated by the estrogen receptor. These antiestrogens interact with the estrogen receptor but they appear to induce only a partial or altered activation of the receptor. This partial or altered activation and the competition with estrogens for binding to the estrogen receptor could explain the estrogen agonist/antagonist properties of antiestrogens.

6. DOCID:11299 SCORE: 0.00359857719719023
DOCNO: 6306804
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: etiology
QUALIFIER: diagnosis
AUTHOR: A Prier A
AUTHOR: B Augereau B
AUTHOR: D Brugel D
AUTHOR: A C Koeger AC
AUTHOR: J P Camus JP
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: La semaine des hôpitaux : organe fondé par l'Association d'enseignement médical des hôpitaux de Paris.
COUNTRY: FRANCE
TITLE: [Non-tuberculous abscesses of the psoas. A case of apparently primary abscess of the psoas due to Staphylococcus aureus]
PUBDATE: 19830401
Abscess of the psoas, which is a well recognized complication in tuberculous osteoarticular infections, can also occur in certain regional diseases of the bones or viscera: common germ osteitis, diverticulosis, colic cancer, appendicitis and, above all, Crohn disease. Abscess of the psoas can also present as an apparently primary pyogenic muscular infection. A case is reported of an abscess of the psoas due to Staphylococcus aureus, which occurred spontaneously in an apparently healthy 50-year-old woman, was cured by surgical drainage, and whose course confirmed its primary nature.

7. DOCID:11449 SCORE: 0.00358305878494289
DOCNO: 6394574
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: history
QUALIFIER: history
AUTHOR: R S Griffith RS
PUBTYPE: Historical Article
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of antimicrobial chemotherapy.
COUNTRY: ENGLAND
TITLE: Vancomycin use--an historical review.
PUBDATE: 19841201
In the early 1950s the increase of antibiotic-resistant strains of Staphylococcus aureus in hospitalized patients with infection stimulated a screening program to develop an effective new agent. A soil sample found in the jungles of Borneo contained a microorganism, Streptomyces orientalis, that produced a substance later called vancomycin. Vancomycin was shown to have antistaphylococcal activity and to be relatively safe when administered to patients. With the resurgence of staphylococcal infections resistant to the newer antistaphylococcal antibiotics, there has been a corresponding increase in the use of vancomycin. Vancomycin is also being used for prophylaxis in patients with reduced renal function undergoing dialysis, for the treatment of patients with antibiotic-induced enterocolitis, and in combination with other antibiotics for 'sterilization' of the intestinal tract in patients with cancer.

8. DOCID:11434 SCORE: 0.00346445403864933
DOCNO: 2412543
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
AUTHOR: L E Hughes LE
PUBTYPE: Journal Article
JOURNALTITLE: The Australian and New Zealand journal of surgery.
COUNTRY: AUSTRALIA
TITLE: A surgeon's view of oncology.
PUBDATE: 19850401
The past thirty years has seen a profound change in emphasis and direction in the management of cancer. In many countries this has been away from traditional surgical management towards specialists trained primarily in medical oncology or radiotherapy. This trend has occurred despite the fact that surgery is still by far the most effective method of treatment of most common cancers. The effectiveness of sound cancer surgery and the importance of local disease control as an element in improving cure rates and palliation needs to be emphasised so that patients are not denied optimal treatment. The case for surgery can best be developed by encouraging special training and expertise in the field of surgical oncology, as one element in the provision of a surgical service for cancer patients.

9. DOCID:14898 SCORE: 0.00338813741526332
DOCNO: 3757740
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: diagnosis
AUTHOR: B C Zhang BC
AUTHOR: N J Wang NJ
AUTHOR: X Y Huang XY
AUTHOR: M R Wang MR
AUTHOR: Q M Zhang QM
AUTHOR: L Q Shao LQ
PUBTYPE: Journal Article
JOURNALTITLE: Zhonghua zhong liu za zhi [Chinese journal of oncology].
COUNTRY: CHINA
TITLE: [Fine needle aspiration cytology in the diagnosis of primary liver cancer]
PUBDATE: 19860701
From Dec. 1979 to Dec. 1984, 171 patients suspicious of primary liver cancer (PLC) were examined by fine needle aspiration cytology (FNAC). In this series, 148 patients were finally diagnosed as PLC. By FNAC, 133 of 148 patients showed positive cytology and 4 suspiciously positive cytology. The overall diagnostic accuracy was 92.6% There was no false positive. Neither spreading or bleeding were observed. The results show that FNAC examination, being simple, rapid and safe, could serve as a reliable way of diagnosing the suspected PLC.

10. DOCID:15462 SCORE: 0.00338752983205801
DOCNO: 3008137
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: R L Stephens RL
PUBTYPE: Journal Article
JOURNALTITLE: Postgraduate medicine.
COUNTRY: UNITED STATES
TITLE: Chemotherapy in adult cancer. When is it most useful?
PUBDATE: 19860401
Much has been accomplished in the cure of cancer with chemotherapy, but much remains to be done. The primary care physician's responsibility is to know which cancers are curable and in which a significant portion of patients may benefit from chemotherapy. Patients with a malignancy in a relatively resistant organ site represent the greatest challenge to the "art" of medicine. Even if more than half of patients with a given malignancy are cured by chemotherapy, the remainder deserve the right to participate in research protocols, an undertaking that might further improve these otherwise substantial gains. As research studies show improved cure rates with antineoplastic agents, the need to reduce both short- and long-term side effects will remain a challenge.

11. DOCID:11919 SCORE: 0.00331263882981401
DOCNO: 6351758
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Chlorides
DESCRIPTOR: Zinc Compounds
QUALIFIER: surgery
QUALIFIER: administration & dosage
AUTHOR: N A Swanson NA
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Archives of dermatology.
COUNTRY: UNITED STATES
TITLE: Mohs surgery. Technique, indications, applications, and the future.
PUBDATE: 19830901
Each year, it is estimated, more than 500,000 new cases of nonmelanoma skin cancer develop. The majority of these cutaneous neoplasms are treated by various modalities that include excision, electrodesiccation and curettage, cryosurgery, and irradiation, with greater than 90% success. Certain of the remaining primary tumors, as well as recurrent carcinomas, present a demanding therapeutic challenge. For these lesions, Mohs surgery has evolved as the most reliable and cost-effective treatment modality, offering maximal preservation of normal tissue and therefore the lowest functional and cosmetic morbidity. In this review, the history and evolution of Mohs surgery and the technique itself will be briefly outlined. The indications for Mohs surgery, together with methods of handling the postoperative wound and future applications of the technique, will be discussed in detail.

12. DOCID:11767 SCORE: 0.00330648691199407
DOCNO: 6702036
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: E Laor E
AUTHOR: Z Schiffman Z
AUTHOR: R E Reid RE
AUTHOR: B M Tolia BM
AUTHOR: S Z Freed SZ
PUBTYPE: Journal Article
JOURNALTITLE: Urology.
COUNTRY: UNITED STATES
TITLE: Sex-dependent variations in natural history of transitional cell carcinoma of bladder.
PUBDATE: 19840301
The records of 196 patients with transitional cell carcinoma of the bladder diagnosed up to 1975 were analyzed for age, sex, tumor histology, and survival parameters. Analysis of the series as a whole showed it to be comparable to literature controls in the male to female ratio, average age at presentation, and in survival data. Sex stratification combined with parametric analysis showed that females had longer recurrence-free survivals and died less frequently of bladder cancer than their male counterparts. In addition, the incidence of high-grade tumors was lower in females. These facts and the comments that follow point to a probable less aggressive natural history of transitional cell carcinoma of the bladder in females.

13. DOCID:9239 SCORE: 0.00322108055794959
DOCNO: 6365356
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: blood
QUALIFIER: blood
QUALIFIER: blood
QUALIFIER: blood
AUTHOR: K W Lam KW
AUTHOR: C Dannaher C
AUTHOR: S Letchford S
AUTHOR: T Eastlund T
AUTHOR: C Y Li CY
AUTHOR: L T Yam LT
PUBTYPE: Journal Article
JOURNALTITLE: Clinical chemistry.
COUNTRY: UNITED STATES
TITLE: Tartrate-resistant acid phosphatase in serum of cancer patients.
PUBDATE: 19840301
Tartrate-resistant acid phosphatase activity determined by enzyme immunoassay was higher in the serum of cancer patients than that in normal blood donors. The highest activity was found among patients having malignancy metastatic to bone. The classic colorimetric method showed a broad range of values among normal blood donors, and the contrast between normal and cancer patients was less obvious. Most of the cancer patients had normal to low alkaline phosphatase activities.

14. DOCID:10215 SCORE: 0.00321003796586404
DOCNO: 6719163
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Lymph Node Excision
QUALIFIER: methods
QUALIFIER: surgery
AUTHOR: J L Powell JL
AUTHOR: M O Burrell MO
AUTHOR: E W Franklin EW
PUBTYPE: Journal Article
JOURNALTITLE: Southern medical journal.
COUNTRY: UNITED STATES
TITLE: Radical hysterectomy and pelvic lymphadenectomy.
PUBDATE: 19840501
In recent years there has been an increasing awareness that radical hysterectomy and pelvic lymphadenectomy can play an important role in the management of early invasive cervical cancer. We present a series of 255 patients who had radical hysterectomy for gynecologic malignancy over a nine-year period. The incidence of ureteral fistulas was 0.8% and of vesical fistulas 1.6%. The operative mortality was 0.78%, which compares favorably with the rates in most larger centers in which radical pelvic operations are common. With proper patient selection and excellent operative technique, survival rates of well over 90%, with minimal complications, can be obtained.