0. DOCID:22913 SCORE: 0.00422217551554887
DOCNO: 7578386
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
QUALIFIER: methods
AUTHOR: P Rossi P
AUTHOR: M Bezzi M
AFFILIATION: Department of Radiology, University of Rome La Sapienza, Policlinico Umberto I, Italy.
PUBTYPE: Journal Article
JOURNALTITLE: Current opinion in oncology.
COUNTRY: UNITED STATES
TITLE: Interventional radiology in gastrointestinal neoplasms.
PUBDATE: 19950701
Interventional radiology plays a significant role in different fields of gastrointestinal oncology. Percutaneous techniques can be used to diagnose and stage bile duct and pancreatic cancer. Palliation of esophageal tumors and malignant biliary obstruction may be achieved with interventional techniques, whereas curative attempts are directed mainly towards primary and secondary liver tumors. The therapeutic potential of interventional radiology is still expanding, as are all other forms of minimally invasive therapy. This article reviews the relevant contributions on this subject that have appeared in the past year. The introduction of new techniques is described, and the results of clinical studies are discussed.


1. DOCID:22740 SCORE: 0.00399348359808298
DOCNO: 7742518
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Laparoscopy
QUALIFIER: surgery
AUTHOR: J M Childers JM
AUTHOR: A Nasseri A
AFFILIATION: Department of Obstetrics and Gynecology, University of Arizona, Tucson, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Current opinion in obstetrics & gynecology.
COUNTRY: UNITED STATES
TITLE: Minimal access surgery in gynecologic cancer: we can, but should we?
PUBDATE: 19950201
Operative laparoscopists continue to refine surgical techniques applicable to patients with gynecologic malignancies. Various techniques for radical hysterectomy and larger series of patients with endometrial cancer have now been reported. The technical feasibility of such operations is being established. Although oncologic patients may enjoy the known benefits of laparoscopic surgery, such as shorter hospitalization, the known shortcomings, such as longer operative times and increased cost, are a concern. The unknown shortcomings and the unknown overall survival of laparoscopically managed patients continue to keep the majority of oncologic surgeons a safe distance away.


2. DOCID:20969 SCORE: 0.00390577742812919
DOCNO: 7821417
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Oxidative Stress
QUALIFIER: metabolism
QUALIFIER: metabolism
AUTHOR: S Toyokuni S
AUTHOR: K Okamoto K
AUTHOR: J Yodoi J
AUTHOR: H Hiai H
AFFILIATION: Department of Pathology, Faculty of Medicine, Kyoto University, Japan.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: FEBS letters.
COUNTRY: NETHERLANDS
TITLE: Persistent oxidative stress in cancer.
PUBDATE: 19950101
DNA of cancers such as renal cell carcinoma and mammary invasive ductal carcinoma, is persistently exposed to more oxidative stress than that of adjacent normal tissue. We suggest that the concept of 'persistent oxidative stress in cancer' may open up a new research area, explaining part of the characteristic tumor biology of cancer such as activated transcription factors and proto-oncogenes, genomic instability, chemotherapy-resistance, invasion and metastasis.


3. DOCID:23775 SCORE: 0.00373613188703648
DOCNO: 7808686
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: secondary
QUALIFIER: secondary
QUALIFIER: complications
QUALIFIER: secondary
QUALIFIER: pathology
QUALIFIER: etiology
AUTHOR: V Bruzzese V
AUTHOR: F Biferali F
AUTHOR: S Paventi S
AFFILIATION: Divisione Medicina Generale, Ospedale S. Giacomo in Augusta, Roma.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Minerva medica.
COUNTRY: ITALY
TITLE: [Neoplastic pericarditis secondary to ovarian adenocarcinoma. Report of a clinical case]
PUBDATE: 19941101
The pericardial metastatic disease is rare in genital cancers but is frequent in all other cancer. The authors report the case of a female affected by both papillary ovarian cancer and pericardial metastatic disease. Carcinomatous pericarditis began with cardiac tamponade. This pericarditis is very rare during ovarian cancer and there is little informations in the literature about it. The clinical picture showed an acuteness that cleared up with many pericardial tapping paracenteses, and after six cycles of polychemotherapy we obtained the disappearance of pericardial effusion and metastasis with total disappearance of abdominal metastases and the total remission of the cancer.


4. DOCID:23400 SCORE: 0.00370394741394787
DOCNO: 9179488
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
QUALIFIER: radiation effects
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
AUTHOR: C MacLeod C
AUTHOR: E Moylan E
AUTHOR: G L Falk GL
AFFILIATION: Department of Radiation Oncology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus / I.S.D.E.
COUNTRY: SCOTLAND
TITLE: Carcinoma of the esophagus treated with radical chemoradiation 19 years after irradiation for recurrent breast cancer.
PUBDATE: 19970401
Prior irradiation to a site is a relative and often absolute contraindication to further irradiation because the tolerance dose of normal tissues is usually exceeded and therefore the risk of serious long-term side-effects is high. This case report describes radical salvage chemoradiation for an esophageal carcinoma in a patient who had prior high-dose neck and chest wall irradiation for the management of a breast cancer 19 years previously.


5. DOCID:21569 SCORE: 0.00348185811444069
DOCNO: 7780111
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: biosynthesis
QUALIFIER: drug effects
QUALIFIER: pharmacology
AUTHOR: X Chen X
AUTHOR: R Han R
AFFILIATION: Department of Pharmacology, Institute of Materia Medica, CAMS, Beijing.
PUBTYPE: Journal Article
JOURNALTITLE: Chinese medical sciences journal = Chung-kuo i hsüeh k'o hsüeh tsa chih / Chinese Academy of Medical Sciences.
COUNTRY: CHINA
TITLE: Effect of glycyrrhetinic acid on DNA damage and unscheduled DNA synthesis induced by benzo(a)pyrene.
PUBDATE: 19950301
Glycyrrhetinic acid (GA) is an active component of Glycyrrhiza uraleusis fisch. In this study, GA was found to inhibit ear edema and ornithine decarboxylase (ODC) activity induced by croton oil in mice. GA could also protect rapid DNA damage and decrease the unscheduled DNA synthesis induced by benzo(a)pyrene. The results demonstrate that GA has a potential cancer chemopreventive activity.


6. DOCID:22906 SCORE: 0.00338884433113843
DOCNO: 8634979
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Health Care Costs
QUALIFIER: economics
AUTHOR: J S Bailes JS
AFFILIATION: American Society of Clinical Oncology, Alexandria, Virginia 22314, USA.
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: The economics of cancer care.
PUBDATE: 19951101
Considerable attention has been paid to the high cost of cancer care. These medical services are expensive, accounting for 10% of total health care expenditures. Factors contributing to high costs include (1) the likelihood that anticancer treatments will lead to costly medical complications: (2) intensive research and development necessary to ensure rapid introduction of a broad array of treatment options; and (3) specialized facilities required for delivery of care. Such efforts as rationing of care and utilizing practice guidelines have been ineffective in controlling costs. To realize savings, we must develop new therapies with sufficient specificity so that anticancer interventions do not impair the patient's general health.


7. DOCID:21554 SCORE: 0.00309344953295806
DOCNO: 8865481
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapy
AUTHOR: B A Lowe BA
AFFILIATION: Division of Urology, Oregon Health Sciences University, Portland 97201, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Seminars in urologic oncology.
COUNTRY: UNITED STATES
TITLE: Management of stage T1a prostate cancer.
PUBDATE: 19960801
The patient with incidentally discovered prostate cancer by transurethral resection of the prostate (TURP) presents a difficult management problem for the clinician. These tumors are small and generally of low biologic potential. Offering aggressive treatment is not necessary in most patients; though in some patients, the tumor is not organ confined. Selecting that patient who may require tumor eradication to optimize survival requires careful analysis of known histological parameters identified at the time of diagnosis, an estimation of projected individual survival, and extensive counseling regarding options.


8. DOCID:23922 SCORE: 0.00301875124073837
DOCNO: 9059411
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Magnetic Resonance Imaging
QUALIFIER: diagnosis
QUALIFIER: diagnosis
AUTHOR: S Mussurakis S
AUTHOR: P J Carleton PJ
AUTHOR: L W Turnbull LW
AFFILIATION: Centre for MR Investigations, University of Hull, Hull Royal Infirmary, United Kingdom.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Acta radiologica (Stockholm, Sweden : 1987)
COUNTRY: DENMARK
TITLE: MR imaging of primary non-Hodgkin's breast lymphoma. A case report.
PUBDATE: 19970101
In this report we describe the MR imaging findings, including dynamic data, in a patient with primary non-Hodgkin's lymphoma of the breast. The precontrast T1-weighted sequence showed several hypointense, ill-defined, non-spiculated masses. In the T2-weighted images the masses showed a hyperintense halo. In the dynamic and postcontrast sequences all lesions enhanced markedly, and a further large mass was discovered. In comparison to mammography and sonography, only MR imaging identified the multicentric extent of the tumour. Differentiation from invasive cancer, based on either MR or conventional imaging features, was not possible.


9. DOCID:23001 SCORE: 0.00282058260270574
DOCNO: 7654826
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: drug therapy
QUALIFIER: drug therapy
AUTHOR: R Tavorath R
AUTHOR: D G Pfister DG
AFFILIATION: Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Current opinion in oncology.
COUNTRY: UNITED STATES
TITLE: Chemotherapy for recurrent disease and combined modality therapies for head and neck cancer.
PUBDATE: 19950501
The identification and development of new agents and innovative treatment approaches remain a priority. The prognosis for patients with recurrent or metastatic head and neck cancer remains poor; thus participation in trials of promising investigational agents is an important option for these individuals. For patients with locally advanced tumors, combined modality treatment is undergoing rapid evolution. The optimal combination and sequence of therapies have yet to be determined. However, available data support an increasing role for chemotherapy especially as part of strategies to preserve organ function and treat unresectable disease.


10. DOCID:22124 SCORE: 0.0027781883635218
DOCNO: 8733712
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: adverse effects
QUALIFIER: etiology
QUALIFIER: adverse effects
AUTHOR: Y K Keung YK
AUTHOR: J Gendreau J
AUTHOR: A Barber A
AUTHOR: E Cobos E
AFFILIATION: Division of Oncology@Hematology, Texas Tech University Health Sciences Center, Lubbock 79430, USA.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Bone marrow transplantation.
COUNTRY: ENGLAND
TITLE: Acute mediastinitis secondary to leakage of parenteral nutrition from a migrated central venous catheter in a patient undergoing autologous bone marrow transplant.
PUBDATE: 19960501
We describe an unusual case of pyrexia of unknown origin in a patient undergoing autologous bone marrow transplantation for metastatic breast cancer. The fever was due to extravasation of lipid-containing hyperalimentation fluid from a migrated central venous catheter into the mediastinum, resulting in mediastinitis and pleurisy. The fever persisted despite broad-spectrum antibiotics and amphotericin B, and finally responded to steroids.


11. DOCID:21498 SCORE: 0.00277272142237699
DOCNO: 8939650
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: metabolism
QUALIFIER: physiology
AUTHOR: D Garrod D
AUTHOR: M Chidgey M
AUTHOR: A North A
AFFILIATION: Epithelial Morphogenesis Research Group, School of Biological Sciences, University of Manchester, 3.239 Stopford Building, Oxford Road, Manchester M13 9PT, UK. David.Garrod@man.ac.uk
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Current opinion in cell biology.
COUNTRY: UNITED STATES
TITLE: Desmosomes: differentiation, development, dynamics and disease.
PUBDATE: 19961001
Recent evidence on the distribution of desmosomal glycoprotein isoforms that shows their combined expression in individual desmosomes has strengthened the belief that the latter are involved in epithelial differentiation and morphogenesis. It has been shown that cellular interactions and protein kinase C can modulate the adhesive properties of desmosomes in epithelial cell sheets. Genetic studies indicate the involvement of desmosomal components in cancer and epidermal diseases.


12. DOCID:22496 SCORE: 0.00263273441937731
DOCNO: 7532383
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: complications
AUTHOR: G Tordjman G
PUBTYPE: Journal Article
JOURNALTITLE: Annales de chirurgie plastique et esthétique.
COUNTRY: FRANCE
TITLE: [Sexuality and genito-urinary cancers]
PUBDATE: 19940201
In mythological terms, cancer symbolizes death and suffering, and sexuality, on the other hand, symbolizes life and pleasure. This diagnosis whether explicit or not, calls for two-fold reflection. Firstly the individual is faced by the inexorable approach of death and is called to bury his fantasies of immortality. Secondly, it also constitutes a threat to the body-image, and this may have profound repercussions on sexuality. The author investigates the impact of genito-urinary cancers and also cancers of the breast, which are included on the basis of its symbolic nature, on the patient's personal life: conjugal dynamism, socio-professional life and, in particular, physiological changes of sexual function.


13. DOCID:22919 SCORE: 0.00262591978315365
DOCNO: 7655647
AUTHOR: T A Mityukova TA
AUTHOR: L N Astakhova LN
AUTHOR: L D Asenchyk LD
AUTHOR: M M Orlov MM
AUTHOR: L VanMiddlesworth L
AFFILIATION: Research Institute of Radiation Medicine, Ministry of Health of Belarus, Minsk.
PUBTYPE: Journal Article
JOURNALTITLE: European journal of endocrinology / European Federation of Endocrine Societies.
COUNTRY: ENGLAND
TITLE: Urinary iodine excretion in Belarus children.
PUBDATE: 19950801
Casual urine samples were collected to determine iodine excretion of 1680 Belarus children during 1990-1994. The subjects, 8-16 years old, were from nine different regions of Belarus; 60% were from the Gomel oblast, which has been associated with relatively high levels of radioiodine fallout and increased incidence of thyroid cancer. Most of the median values indicate borderline/low iodine intake or mild iodine deficiency. Ranges were wide but 163 children excreted < 20 micrograms I/l urine and they should be considered severely deficient in iodine.


14. DOCID:23117 SCORE: 0.00249435028333429
DOCNO: 9295070
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Graves Disease
DESCRIPTOR: Muscle Neoplasms
DESCRIPTOR: Thyroid Neoplasms
AUTHOR: H A Druker HA
AUTHOR: L Kasprzak L
AUTHOR: L R Bégin LR
AUTHOR: S Jothy S
AUTHOR: S A Narod SA
AUTHOR: W D Foulkes WD
AFFILIATION: Department of Human Genetics, McGill University, Montreal, Quebec, Canada.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: American journal of medical genetics.
COUNTRY: UNITED STATES
TITLE: Family with Graves disease, multinodular goiter, nonmedullary thyroid carcinoma, and alveolar rhabdomyosarcoma.
PUBDATE: 19971001
Benign thyroid disease is a risk factor for nonmedullary thyroid carcinoma [Houlston and Stratton: Q J Med 88:685-693, 1995]. We report on a family with 7 members with benign and/or malignant thyroid neoplasia; one affected female died of a paravertebral alveolar rhabdomyosarcoma at age 20. The occurrence of thyroid nodular hyperplasia, nonmedullary thyroid cancer, and rhabdomyosarcoma in the same family may be due to chance, common environmental factors, or, most likely, genetic predisposition.