0. DOCID:14757 SCORE: 0.00391033171322832
DOCNO: 2767670
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Gene Frequency
DESCRIPTOR: Names
QUALIFIER: genetics
AUTHOR: R K Cleek RK
PUBTYPE: Journal Article
JOURNALTITLE: Human biology; an international record of research.
COUNTRY: UNITED STATES
TITLE: Surnames and cancer genes.
PUBDATE: 19890401
The surname analysis of over 40,000 Wisconsin cancer mortalities for the period 1979 through 1985 partially reveals the relative genetic component of various major cancers. The surname frequencies and frequency distributions indicate that both tumor-promoting and tumor-suppressing genes may be involved. A number of cancers exhibit some probable genetic component, but genetic involvement seems marked in male and female leukemia and male lung cancer. Evidence is found for autosomal and sex-linked, dominant and recessive patterns. Most surprising is the strong evidence for tumor-suppressing genes for most cancers. Clustering of surnames across cancers evinces a number of Wisconsin surnames that may be involved in a cancer family syndrome.

1. DOCID:15352 SCORE: 0.00361487879360311
DOCNO: 3257804
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Tomography, Emission-Computed
QUALIFIER: radionuclide imaging
QUALIFIER: radionuclide imaging
AUTHOR: R I Gabuniia RI
AUTHOR: T I Zaĭtseva TI
AUTHOR: Iu B Bogdasarov IuB
PUBTYPE: Journal Article
JOURNALTITLE: Meditsinskaia radiologiia.
COUNTRY: USSR
TITLE: [Emission computed tomography in the diagnosis of lung diseases]
PUBDATE: 19880201
Investigations of pulmonary perfusion with 99m Tc-MMA by the method of emission computed tomography (ECT) were conducted in 172 patients with different pulmonary diseases. The authors described ECT procedure of the lungs and scinti-tomographic symptomatology typical of the normal lungs and different types of pulmonary pathology (lung cancer, benign tumors, metastases and chronic inflammatory pulmonary processes). A high sensitivity of ECT as compared to poly-positional scintigraphy was shown. The obtained results suggested that ECT permitted more specified and earlier diagnosis of pulmonary perfusion disorders which was of great importance in the diagnosis of different pulmonary diseases as well as in the assessment of therapeutic efficacy.

2. DOCID:13885 SCORE: 0.00339575156165959
DOCNO: 2626114
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
AUTHOR: P Jayalakshmi P
AUTHOR: R Pathmanathan R
AUTHOR: R Raman R
AUTHOR: U Prasad U
PUBTYPE: Journal Article
JOURNALTITLE: The Medical journal of Malaysia.
COUNTRY: MALAYSIA
TITLE: Microscopically diagnosed head and neck cancers in the University Hospital, Kuala Lumpur.
PUBDATE: 19890301
A retrospective study of 1000 cases of microscopically diagnosed head and neck cancers in the University Hospital, Kuala Lumpur was done. Head and neck neoplasms comprise 7.1% of all tumours diagnosed in this Hospital and the commonest sites of involvement are the nasopharynx (29.1%), cervical lymph nodes (22.6%), oral cavity (10.2%), thyroid (8.2%) and skin (6.5%). Histologically, 87% of tumours are epithelial in nature. The results of this study show that nasopharyngeal carcinoma is commonest in Chinese males, while oral and laryngeal malignancies occur more frequently in Indians.

3. DOCID:15190 SCORE: 0.00279502275104283
DOCNO: 3405455
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: etiology
AUTHOR: F Galietti F
AUTHOR: G E Giorgis GE
AUTHOR: A Oliaro A
AUTHOR: A Boidi-Trotti A
AUTHOR: A Ardizzi A
AUTHOR: S Barberis S
AFFILIATION: Ospedale Pneumologico S. Luigi Gonzaga, Orbassano, Torino.
PUBTYPE: Journal Article
JOURNALTITLE: Minerva medica.
COUNTRY: ITALY
TITLE: [Post-actinic pulmonary fibrosis. Longitudinal study of 279 cases]
PUBDATE: 19880701
The incidence and extent of postactinic pulmonary fibrosis was investigated in relation to the different types of radiation therapy. For this purpose, 131 patients treated with fast electron (for breast cancer) and 148 patients treated with TCT (for breast cancer and cancer of other nature) observed in the period 1976-1987 were followed up (from 13 months to 7 years). The frequency of postactinic fibrosis was much less in the first group of patients than the second (6.61% vs 18.99%); further, the functional damage in these patients proved less and developed in a less unfavourable way.

4. DOCID:15077 SCORE: 0.00272932001991072
DOCNO: 2470931
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: enzymology
QUALIFIER: biosynthesis
QUALIFIER: enzymology
AUTHOR: T Kamio T
AUTHOR: K Sameshima K
AUTHOR: J Irie J
AUTHOR: K Shigematsu K
AUTHOR: K Kawai K
AUTHOR: H Tsuchiyama H
AUTHOR: M Nakano M
AFFILIATION: 2nd Dept. of Pathology, School of Med., Nagasaki Univ.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [Two cases of amylase-producing lung cancer]
PUBDATE: 19890501
In 1951, Weiss et al. first reported a case of an amylase-producing lung cancer. Since then, reports on immunohistochemical, ultrastructural, and biochemical studies have been published. We recently have experienced two autopsy cases of lung cancer that manifested high amylase activity in the serum, urine, and pleural effusions. Histologically, both lung cancers were classified as being well differentiated adenocarcinomas, and immunohistochemically, the tumor cells showed positive immunoreactivity for amylase. This paper discusses the histogenesis of amylase-producing lung cancers and cases found in the literature.

5. DOCID:15034 SCORE: 0.00262577143233834
DOCNO: 3594361
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: etiology
QUALIFIER: surgery
AUTHOR: A Maringhini A
AUTHOR: R Thiruvengadam R
AUTHOR: L J Melton LJ
AUTHOR: V S Hench VS
AUTHOR: A R Zinsmeister AR
AUTHOR: E P DiMagno EP
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Pancreatic cancer risk following gastric surgery.
PUBDATE: 19870701
To estimate the risk of pancreatic cancer after gastric surgery for benign disease, we followed all 336 residents of Olmsted County, Minnesota, who had surgical treatment for benign peptic ulcer disease during the years 1935 to 1959. These patients were followed for 6549 person-years of observation. Pancreatic cancer developed in only one patient although 1.6 primary pancreatic cancers were expected (relative risk 0.64; 95% confidence interval, 0.02 to 3.53) based on pancreatic cancer incidence rates for the general population of Olmsted County. We conclude that in our study the incidence of pancreatic cancer is not significantly increased after gastric surgery.

6. DOCID:14904 SCORE: 0.00258482076825134
DOCNO: 2702566
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: A G Bernal AG
AUTHOR: J J Cruz JJ
AUTHOR: P Sánchez P
AUTHOR: A Muñoz A
AUTHOR: A Nieto A
AUTHOR: E Fonseca E
AUTHOR: R Calle R
AUTHOR: J L Gómez JL
AFFILIATION: Department of Oncology, Hospital Clínico Universitario, Salamamca, Spain.
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Four-day continuous infusion of cisplatin and 5-fluorouracil in head and neck cancer.
PUBDATE: 19890501
A combination of cisplatin and 5-fluorouracil, both administered 4 days continuously as infusion, was assessed in advanced head and neck cancer. Of the 37 patients studied, there were 15 complete and 17 partial responses (40.5% and 45.9%, respectively). Survival is 79.1% at 22 months. None of the patients in complete response has relapsed. In general toxic effects were moderate. Given as initial treatment, the regimen is effective and of considerable use in this type of patient.

7. DOCID:14861 SCORE: 0.00258482038002419
DOCNO: 3294269
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Neoplasm Metastasis
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: I J Fidler IJ
AFFILIATION: Department of Cell Biology, University of Texas M.D. Anderson Cancer Center, Houston 77030.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The Journal of dermatologic surgery and oncology.
COUNTRY: UNITED STATES
TITLE: The biology of melanoma metastasis.
PUBDATE: 19880801
The process of cancer metastasis is sequential and selective and contains stochastic elements. The growth of melanoma metastases represents the endpoint of many lethal events that few tumor cells can survive. Primary tumors consist of multiple subpopulations of cells with heterogeneous metastatic properties, and the outcome of metastasis depends on the interplay of metastatic tumor cells with various host factors. This viewpoint is more optimistic than that of metastasis as a random process. A selective biological process is regulated by the interaction of tumor cells with their host, and these complex interactions can now be studied and manipulated.

8. DOCID:13679 SCORE: 0.00246362494899202
DOCNO: 2538778
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: etiology
QUALIFIER: complications
QUALIFIER: etiology
QUALIFIER: complications
QUALIFIER: complications
AUTHOR: L Amico L
AUTHOR: L R Caplan LR
AUTHOR: C Thomas C
AFFILIATION: Department of Neurology, Michael Reese Hospital, University of Chicago, IL.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Neurology.
COUNTRY: UNITED STATES
TITLE: Cerebrovascular complications of mucinous cancers.
PUBDATE: 19890401
Six patients with mucinous cancer (2 colonic, 2 pancreatic, and 2 pulmonary origin) had necropsy evidence of thrombosis of large and small systemic, extracranial, and intracranial arteries and veins, and multiple cerebral infarcts and small hemorrhages. On microscopic examination, we found small infarcts and hemorrhages within the brain and mucin within vessels, macrophages, and in areas of infarction. The clinical picture included strokes and encephalopathy. Mucin-producing cancers can be associated with a coagulopathy that causes extensive occlusive vascular disease.

9. DOCID:14045 SCORE: 0.00246339010405894
DOCNO: 3789603
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: methods
QUALIFIER: radiography
QUALIFIER: methods
AUTHOR: M J Lee MJ
AUTHOR: J R Lee JR
AUTHOR: H Thompson H
AUTHOR: G D Oates GD
PUBTYPE: Journal Article
JOURNALTITLE: Annals of the Royal College of Surgeons of England.
COUNTRY: ENGLAND
TITLE: Mammographic identification and biopsy of occult breast cancer.
PUBDATE: 19860701
During a 9 year period we excised 70 suspicious non-palpable breast lesions detected by mammography. We found the most effective method of preoperative localisation to be insertion of a self retaining wire, and this procedure was facilitated by a Perspex grid incorporated in the mammography equipment. Thirty biopsies (43%) were found to be malignant, of which 14 contained invasive and 16 in situ carcinoma. The presence of malignancy could not be predicted from the mammographic appearance, although in situ cancer was always associated with microcalcification.

10. DOCID:13922 SCORE: 0.00244709366110245
DOCNO: 2956477
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: secondary
QUALIFIER: secondary
QUALIFIER: pathology
AUTHOR: M E Fisher ME
AUTHOR: R I Gabuniia RI
AUTHOR: E K Kolesnikova EK
AUTHOR: S A Bal'ter SA
AUTHOR: I V Ostrovtsev IV
PUBTYPE: Journal Article
JOURNALTITLE: Meditsinskaia radiologiia.
COUNTRY: USSR
TITLE: [Complex preoperative diagnosis of the dissemination of stomach cancer to abdominal and retroperitoneal organs and tissues]
PUBDATE: 19870701
An analysis of 136 cases of stomach cancer led to the determination of the role and place of gamma-topography, echography, computerized x-ray tomography, angiography and laparoscopy in specified preoperative diagnosis of extra-organ spreading of primary tumors. The informative value and shortcomings of certain methods were shown. A high accuracy of the entire set of diagnostic procedures (94.8%) in the preoperative definition of stomach cancer involvement of the abdominal and retroperitoneal organs and tissues was emphasized.

11. DOCID:13618 SCORE: 0.0024233604227471
DOCNO: 2725920
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: blood supply
AUTHOR: G Viglione G
AUTHOR: R Rivetti R
AUTHOR: F Lavagna F
AUTHOR: Q Cartia Q
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Minerva chirurgica.
COUNTRY: ITALY
TITLE: [Revascularization of the hepatic artery. Apropos of a case]
PUBDATE: 19890301
A case of emergency revascularisation of the hepatic artery for liver necrosis following its forced ligature during corpo-caudal pancreatectomy for cancer of the pancreas in referred. Necrosis protection mechanisms, namely higher portal flow, increase in O2 extraction and collateral circulation are analysed. The therapeutic aids for preventing this serious event are presented. It is considered that peripheral expansion of the hepatic artery thrombosis prevented the installation of a valid collateral circulation, although the hypothesis of a reduction in portal flow should not be ignored.

12. DOCID:12936 SCORE: 0.00238993291125723
DOCNO: 3587888
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: genetics
QUALIFIER: genetics
QUALIFIER: genetics
AUTHOR: D J Derkinderen DJ
AUTHOR: J W Koten JW
AUTHOR: R Wolterbeek R
AUTHOR: F A Beemer FA
AUTHOR: K E Tan KE
AUTHOR: W Den Otter W
PUBTYPE: Journal Article
JOURNALTITLE: Ophthalmic paediatrics and genetics.
COUNTRY: NETHERLANDS
TITLE: Non-ocular cancer in hereditary retinoblastoma survivors and relatives.
PUBDATE: 19870301
An epidemiological survey has been carried out to establish the incidence of second malignant neoplasms in hereditary retinoblastoma survivors in The Netherlands and the relative risk of cancer in non-affected relatives. The cumulative incidence of second neoplasms was 19% at the age of 35 years. Fathers, unaffected by retinoblastoma, were at risk for pancreatic cancer, the relative risk being 8.3.

13. DOCID:14569 SCORE: 0.00235667072730087
DOCNO: 3387892
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: complications
QUALIFIER: complications
AUTHOR: A McCallum A
AUTHOR: M A Eastwood MA
AUTHOR: A N Smith AN
AUTHOR: P M Fulton PM
AFFILIATION: Gastro-intestinal Unit, University of Edinburgh, Western General Hospital, U.K.
PUBTYPE: Journal Article
JOURNALTITLE: Scandinavian journal of gastroenterology.
COUNTRY: NORWAY
TITLE: Colonic diverticulosis in patients with colorectal cancer and in controls.
PUBDATE: 19880401
The barium enemas of 119 patients with colorectal cancer and 119 age-matched controls were examined for evidence of diverticula. Amongst men, 39.6% of patients with colorectal cancer had diverticulosis, compared with 50% in the control group. In the women, 39.3% of patients with colorectal cancer had diverticular disease, compared with 36% of the controls. There appears to be no significant aetiologic association between the two conditions, since they do not occur together more frequently than in controls, although each is reputedly the result of fibre lack.

14. DOCID:13275 SCORE: 0.00229337156660496
DOCNO: 3046306
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Diet
QUALIFIER: metabolism
QUALIFIER: chemically induced
QUALIFIER: metabolism
AUTHOR: P P Nair PP
AFFILIATION: Lipid Nutrition Laboratory, US Department of Agriculture, Beltsville, MD 20705.
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: The American journal of clinical nutrition.
COUNTRY: UNITED STATES
TITLE: Role of bile acids and neutral sterols in carcinogenesis.
PUBDATE: 19880901
Epidemiological evidence regarding cancer causation suggests the existence of a strong link to diet-related lifestyles. Neutral sterols and bile acids constitute a group of metabolic endproducts known to have multiple interactions both from the standpoint of being influenced by diet as well as from the standpoint of their role in cellular and molecular processes relating to carcinogenesis. Epidemiological and experimental studies on the possible role of these steroid metabolites are reviewed.