0. DOCID:11603 SCORE: 0.00454862041274072
DOCNO: 3883219
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: administration & dosage
QUALIFIER: drug therapy
QUALIFIER: pathology
AUTHOR: B A Rodan BA
AUTHOR: F L Cohen FL
AUTHOR: W J Bean WJ
AUTHOR: S N Martyak SN
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Neurosurgery.
COUNTRY: UNITED STATES
TITLE: Fibrous mass complicating epidural morphine infusion.
PUBDATE: 19850101
The benefits of continuous epidural morphine infusion using an implanted pump delivery system to control intractable cancer pain have recently been described. Most articles on this subject relate to dosage, technique, degree of pain relief, and tolerance. There are some anticipated complications of the treatment related to the surgical implantation of the system and drug toxicity. We present a complication presumably related to the epidural catheter. A fibrous reaction that developed around the catheter tip progressed into a mass. This caused a significant displacement of the spinal cord with the development of long tract symptoms. Identification of this abnormality using myelography and computed tomography led to prompt surgical decompression resulting in improvement of the patient's condition.


1. DOCID:14757 SCORE: 0.00391033171322832
DOCNO: 2767670
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Gene Frequency
DESCRIPTOR: Names
QUALIFIER: genetics
AUTHOR: R K Cleek RK
PUBTYPE: Journal Article
JOURNALTITLE: Human biology; an international record of research.
COUNTRY: UNITED STATES
TITLE: Surnames and cancer genes.
PUBDATE: 19890401
The surname analysis of over 40,000 Wisconsin cancer mortalities for the period 1979 through 1985 partially reveals the relative genetic component of various major cancers. The surname frequencies and frequency distributions indicate that both tumor-promoting and tumor-suppressing genes may be involved. A number of cancers exhibit some probable genetic component, but genetic involvement seems marked in male and female leukemia and male lung cancer. Evidence is found for autosomal and sex-linked, dominant and recessive patterns. Most surprising is the strong evidence for tumor-suppressing genes for most cancers. Clustering of surnames across cancers evinces a number of Wisconsin surnames that may be involved in a cancer family syndrome.


2. DOCID:15352 SCORE: 0.00361487879360311
DOCNO: 3257804
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Tomography, Emission-Computed
QUALIFIER: radionuclide imaging
QUALIFIER: radionuclide imaging
AUTHOR: R I Gabuniia RI
AUTHOR: T I Zaĭtseva TI
AUTHOR: Iu B Bogdasarov IuB
PUBTYPE: Journal Article
JOURNALTITLE: Meditsinskaia radiologiia.
COUNTRY: USSR
TITLE: [Emission computed tomography in the diagnosis of lung diseases]
PUBDATE: 19880201
Investigations of pulmonary perfusion with 99m Tc-MMA by the method of emission computed tomography (ECT) were conducted in 172 patients with different pulmonary diseases. The authors described ECT procedure of the lungs and scinti-tomographic symptomatology typical of the normal lungs and different types of pulmonary pathology (lung cancer, benign tumors, metastases and chronic inflammatory pulmonary processes). A high sensitivity of ECT as compared to poly-positional scintigraphy was shown. The obtained results suggested that ECT permitted more specified and earlier diagnosis of pulmonary perfusion disorders which was of great importance in the diagnosis of different pulmonary diseases as well as in the assessment of therapeutic efficacy.


3. DOCID:10218 SCORE: 0.00360283984516884
DOCNO: 6546864
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: microbiology
QUALIFIER: microbiology
AUTHOR: J S Warren JS
AUTHOR: J W Smith JW
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Archives of pathology & laboratory medicine.
COUNTRY: UNITED STATES
TITLE: Pasteurella multocida urinary tract infection.
PUBDATE: 19840501
Most Pasteurella multocida infections in humans have been associated with animal bites or scratches. While a variety of infections involving P multocida, unassociated with animal trauma, have been described, infections of the urinary tract are rare. We studied a case in which P multocida was isolated from the urine of a woman with advanced uterine cervical cancer. In most of the cases in which P multocida has been isolated from urine, the patients have had anatomic defects of the urinary tract, as well as an underlying chronic illness. These host-related characteristics appear to be important in the pathogenesis of P multocida urinary tract infection.


4. DOCID:13885 SCORE: 0.00339575156165959
DOCNO: 2626114
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
AUTHOR: P Jayalakshmi P
AUTHOR: R Pathmanathan R
AUTHOR: R Raman R
AUTHOR: U Prasad U
PUBTYPE: Journal Article
JOURNALTITLE: The Medical journal of Malaysia.
COUNTRY: MALAYSIA
TITLE: Microscopically diagnosed head and neck cancers in the University Hospital, Kuala Lumpur.
PUBDATE: 19890301
A retrospective study of 1000 cases of microscopically diagnosed head and neck cancers in the University Hospital, Kuala Lumpur was done. Head and neck neoplasms comprise 7.1% of all tumours diagnosed in this Hospital and the commonest sites of involvement are the nasopharynx (29.1%), cervical lymph nodes (22.6%), oral cavity (10.2%), thyroid (8.2%) and skin (6.5%). Histologically, 87% of tumours are epithelial in nature. The results of this study show that nasopharyngeal carcinoma is commonest in Chinese males, while oral and laryngeal malignancies occur more frequently in Indians.


5. DOCID:8268 SCORE: 0.00330490737676129
DOCNO: 3006904
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
AUTHOR: R E Walsh RE
AUTHOR: J D Bonnet JD
AUTHOR: P M Kroening PM
AUTHOR: R F Peterson RF
AUTHOR: G V Brindley GV
PUBTYPE: Journal Article
JOURNALTITLE: Clinics in geriatric medicine.
COUNTRY: UNITED STATES
TITLE: Primary malignant pulmonary tumors in the older patient.
PUBDATE: 19850501
The incidence of lung cancer, the most common visceral malignancy, is increasing in the elderly patient. Careful preoperative preparation and postoperative care will allow some of these patients to have surgical resections. Radiotherapy and chemotherapy offer benefits for those patients who cannot have a curative surgical resection.


6. DOCID:9751 SCORE: 0.00317696504083024
DOCNO: 3912080
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: enzymology
QUALIFIER: diagnostic use
AUTHOR: V Y Rogalsky VY
AUTHOR: I H Koven IH
AUTHOR: D R Miller DR
AUTHOR: A Pollard A
PUBTYPE: Journal Article
JOURNALTITLE: Clinical biochemistry.
COUNTRY: CANADA
TITLE: Macro creatine kinase type 2 in human colonic tissues.
PUBDATE: 19851201
Macro creatine kinase type 2 (MCK-2) is a promising new tumour marker for carcinoma of the colon. We have purified it from tumour tissue, from serum and, for the first time, from normal colonic epithelium and identified it in a tissue culture line of colon cancer cells. The molecular weight of each preparation, regardless of the source, was similar. Its consistent presence in tumours and in normal colon, contrasted to its variable appearance in serum, implies that there are other factors affecting its release into, or removal from, the circulation.


7. DOCID:11614 SCORE: 0.00316512731696117
DOCNO: 6471418
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pharmacology
QUALIFIER: pathology
AUTHOR: Y Hanatani Y
AUTHOR: T Kubota T
AUTHOR: K Ishibiki K
AUTHOR: O Abe O
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [In vitro chemosensitivity test of human solid cancer: 3H-thymidine uptake inhibition test]
PUBDATE: 19840701
In vitro chemosensitivity test of human solid cancers, serially transplanted into nude mice was performed by detecting the inhibitory rate of 3H-thymidine incorporation to cancer cells. And the results of in vitro chemosensitivity test were compared with those in nude mice. This in vitro chemosensitivity test could present the quantitative results from a relatively small number of cancer cells within a short term (48 hours). Additionally, many samples could be handled at the same time by using microtestplates and a semiautomatic multiple cell harvester. The predictability of this in vitro chemosensitivity test to the in vivo effects was 80.6% (29/36) with 3 false positive and 4 false negative cases.


8. DOCID:11033 SCORE: 0.00308994721185028
DOCNO: 6653531
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: adverse effects
AUTHOR: M A Mehlman MA
PUBTYPE: Journal Article
JOURNALTITLE: Environmental health perspectives.
COUNTRY: UNITED STATES
TITLE: Current toxicological information as the basis for sulfur oxide standards.
PUBDATE: 19831001
The ambient air quality standard established in 1973 is 0.03 ppm annual average for sulfur dioxide and 0.075 mg/m3 for particulates. It is now generally believed that the toxicity of sulfur oxides in ambient air is significantly influenced by the coincident presence of particulates. Inhalation of 1 ppm of sulfur dioxide for 2 hr may produce alterations in pulmonary ventilatory function, both in normal and asthmatic subjects. Effects obtained at 0.5 ppm of sulfur dioxide are controversial and of questionable biological significance. No clear evidence exists that sulfur dioxide or bisulfite causes mutagenicity in mammals, and it is concluded from a variety of animal experiments that long-term exposure to sulfur dioxide alone does not cause cancer.


9. DOCID:11037 SCORE: 0.00298054055412972
DOCNO: 6225394
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analogs & derivatives
QUALIFIER: administration & dosage
QUALIFIER: administration & dosage
QUALIFIER: drug therapy
QUALIFIER: administration & dosage
AUTHOR: S Yokota S
AUTHOR: J Yoshida J
AUTHOR: Y Fuse Y
AUTHOR: K Nishida K
AUTHOR: T Abe T
AUTHOR: T Takino T
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gan to kagaku ryoho. Cancer & chemotherapy.
COUNTRY: JAPAN
TITLE: [Immunochemotherapy with tegafur and schizophyllan for stomach cancer--report of 2 cases]
PUBDATE: 19830901
Two cases of gastric cancer were treated with immunochemotherapy using Tegafur and Schizophyllan. In one case, a marked reduction in the size of metastatic liver tumor and disappearance of most subjective symptoms were observed. The response continued even 8 months after the initial treatment. In the other case, no marked symptoms except occasional dysphagis have been noted for 2 years and 2 months since diagnosis, although the primary tumor size has remained unchanged. Thus, it is presumed that the combined immunochemotherapy regimen may be useful in the treatment of advanced gastric cancer.


10. DOCID:9469 SCORE: 0.00290831661230955
DOCNO: 6828016
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: O F Dent OF
AUTHOR: P H Chapuis PH
AUTHOR: K J Goulston KJ
PUBTYPE: Journal Article
JOURNALTITLE: The Medical journal of Australia.
COUNTRY: AUSTRALIA
TITLE: Relationship of survival to stage of the tumour and duration of symptoms in colorectal cancer.
PUBDATE: 19830301
It has been suggested that reduction of diagnostic delay in symptomatic colorectal cancer will not improve survival. Published reports show varying effects of duration of symptoms both on stage of cancer and on survival. However, tumour stage can be measured only at the end of the symptomatic period and, therefore, conclusions cannot be drawn about early diagnosis of symptomatic colorectal cancer and its effect on survival. On current evidence, early diagnosis and treatment may improve survival and should be encouraged.


11. DOCID:15190 SCORE: 0.00279502275104283
DOCNO: 3405455
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: etiology
QUALIFIER: etiology
AUTHOR: F Galietti F
AUTHOR: G E Giorgis GE
AUTHOR: A Oliaro A
AUTHOR: A Boidi-Trotti A
AUTHOR: A Ardizzi A
AUTHOR: S Barberis S
AFFILIATION: Ospedale Pneumologico S. Luigi Gonzaga, Orbassano, Torino.
PUBTYPE: Journal Article
JOURNALTITLE: Minerva medica.
COUNTRY: ITALY
TITLE: [Post-actinic pulmonary fibrosis. Longitudinal study of 279 cases]
PUBDATE: 19880701
The incidence and extent of postactinic pulmonary fibrosis was investigated in relation to the different types of radiation therapy. For this purpose, 131 patients treated with fast electron (for breast cancer) and 148 patients treated with TCT (for breast cancer and cancer of other nature) observed in the period 1976-1987 were followed up (from 13 months to 7 years). The frequency of postactinic fibrosis was much less in the first group of patients than the second (6.61% vs 18.99%); further, the functional damage in these patients proved less and developed in a less unfavourable way.


12. DOCID:15077 SCORE: 0.00272932001991072
DOCNO: 2470931
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: enzymology
QUALIFIER: biosynthesis
QUALIFIER: enzymology
AUTHOR: T Kamio T
AUTHOR: K Sameshima K
AUTHOR: J Irie J
AUTHOR: K Shigematsu K
AUTHOR: K Kawai K
AUTHOR: H Tsuchiyama H
AUTHOR: M Nakano M
AFFILIATION: 2nd Dept. of Pathology, School of Med., Nagasaki Univ.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Gan no rinsho. Japan journal of cancer clinics.
COUNTRY: JAPAN
TITLE: [Two cases of amylase-producing lung cancer]
PUBDATE: 19890501
In 1951, Weiss et al. first reported a case of an amylase-producing lung cancer. Since then, reports on immunohistochemical, ultrastructural, and biochemical studies have been published. We recently have experienced two autopsy cases of lung cancer that manifested high amylase activity in the serum, urine, and pleural effusions. Histologically, both lung cancers were classified as being well differentiated adenocarcinomas, and immunohistochemically, the tumor cells showed positive immunoreactivity for amylase. This paper discusses the histogenesis of amylase-producing lung cancers and cases found in the literature.


13. DOCID:9426 SCORE: 0.00270964000341433
DOCNO: 6432073
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: immunology
QUALIFIER: immunology
AUTHOR: A P Savinskaia AP
PUBTYPE: Journal Article
JOURNALTITLE: Biulleten' eksperimental'noĭ biologii i meditsiny.
COUNTRY: USSR
TITLE: [Changes in antitumor resistance during chemical carcinogenesis]
PUBDATE: 19840801
Subcutaneous injection of 4 mg DMBA to noninbred rats leads to a considerable decrease in host resistance to cancer, which progresses with tumor growth. The rats with inhibited host resistance to cancer accepted well, at the stage of tumor germ, the DMBA-induced tumors from other animals, permitting them to grow--the phenomenon that was not observed in normal noninbred young rats. At the stage of clinically demonstrable nodules at the sites of DMBA injections, the tumors with different transplantability did not only get adapted but developed distant metastases in part of the animals.


14. DOCID:9412 SCORE: 0.00270963697849358
DOCNO: 6312787
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiography
QUALIFIER: radiography
QUALIFIER: radiography
QUALIFIER: radiography
AUTHOR: B Felson B
AUTHOR: G Ralaisomay G
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: AJR. American journal of roentgenology.
COUNTRY: UNITED STATES
TITLE: Carcinoma of the lung complicating lipoid pneumonia.
PUBDATE: 19831101
The authors have encountered four cases of oil aspiration pneumonia complicated by carcinoma. Each had a clear-cut history of chronic intake of an oily substance, radiographic changes, and histologically documented oil aspiration pneumonia. Lung cancer later appeared in the involved area. A small number of similar cases also have been reported. The implication is that oil aspiration pneumonitis may induce bronchogenic carcinoma, particularly either the alveolar cell or the squamous cell variety. The radiographic diagnosis of the malignant transformation is difficult, and consequently the prognosis is poor.