0. DOCID:8878 SCORE: 0.000864463844949942
DOCNO: 6708220
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
QUALIFIER: adverse effects
QUALIFIER: etiology
AUTHOR: A C Kinn AC
AUTHOR: B Lantz B
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of urology.
COUNTRY: UNITED STATES
TITLE: Vitamin B12 deficiency after irradiation for bladder carcinoma.
PUBDATE: 19840501
Vitamin B12 deficiency was found in 10 of 41 patients who underwent radiotherapy before cystectomy with Bricker urinary diversion for carcinoma of the bladder. Of 13 patients given full irradiation because of inoperable bladder cancer 5 had malabsorption of vitamin B12. Serum folic acid was normal in these patients, indicating predominantly ileal irradiation sequelae. Routine evaluation of serum vitamin B12 after radiotherapy is recommended so that appropriate medication can be given, if possible before neurological symptoms appear.

1. DOCID:10242 SCORE: 0.000560572892624995
DOCNO: 6839297
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Heat
QUALIFIER: immunology
AUTHOR: A Izumi A
AUTHOR: S Koga S
AUTHOR: M Maeta M
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: Effects of in vitro hyperthermia on murine and human lymphocytes.
PUBDATE: 19830601
The effect of in vitro hyperthermia on the immune response of murine and human lymphocytes was investigated. Viability, blastogenesis and cytotoxic activity of murine lymphocytes were reduced at 39 and 42 degrees C hyperthermia. In human lymphocytes, rosette formation inhibition depended on heating-time and temperature. PHA-induced lymphocyte blastogenesis was markedly inhibited at 42 degrees C, irrespective of the duration of exposure and of the origin of the cells, although it was enhanced in some patients at 39 degrees C. Therefore, the possibility of hyperthermia-induced inhibition of the host immune response must be considered in clinical trials of total-body hyperthermia for cancer.

2. DOCID:8678 SCORE: 0.000559619321840874
DOCNO: 6412281
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: epidemiology
QUALIFIER: epidemiology
AUTHOR: H N Hwang HN
PUBTYPE: Journal Article
JOURNALTITLE: Radiology.
COUNTRY: UNITED STATES
TITLE: Nasopharyngeal carcinoma in the people's Republic of China: incidence, treatment, and survival rates.
PUBDATE: 19831001
The incidence, treatment regimens, and survival rates for nasopharyngeal carcinoma in China, one of the most common cancers in that country, are reviewed. Although treated almost exclusively with megavoltage photon therapy, in some cancer centers intracavitary radium insertions are used to increase the radiation dose to the primary tumor site. A histological study of these tumors shows that patients whose tumors are well-differentiated and contain an abundance of lymphocytes have the best prognosis.

3. DOCID:8510 SCORE: 0.000559406733260636
DOCNO: 3974941
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: blood
QUALIFIER: blood
AUTHOR: M Mancuso M
AUTHOR: E Leonardo E
AUTHOR: B Sanfilippo B
AUTHOR: C Dogliotti C
AUTHOR: F Pischedda F
AUTHOR: A Oliaro A
AUTHOR: P Debernochi P
PUBTYPE: Journal Article
JOURNALTITLE: Minerva medica.
COUNTRY: ITALY
TITLE: [Immuno-oncologic monitoring of patients with bronchial carcinoma. III. Plasma glycoproteins]
PUBDATE: 19850201
Alpha and beta serum glycoprotein levels were determined in lung cancer patients at time of diagnosis and during the natural course of the disease. The results do not suggest that these glycoproteins can be used as tumour markers. Moreover, some glycoproteins, which have activity in cell-mediated processes and macrophage functions, can suggest prognosis.

4. DOCID:9802 SCORE: 0.000559373015939776
DOCNO: 4059060
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Radioisotope Renography
QUALIFIER: adverse effects
QUALIFIER: diagnostic use
QUALIFIER: drug effects
QUALIFIER: drug therapy
AUTHOR: W Hengst W
AUTHOR: H Wieler H
AUTHOR: U Rabs U
AUTHOR: R A Bürger RA
PUBTYPE: Journal Article
JOURNALTITLE: Nuklearmedizin.
COUNTRY: GERMANY, WEST
TITLE: 131I-Orthoiodohippurate clearance in the detection of cisplatin nephrotoxicity.
PUBDATE: 19850601
In this study, 26 patients were treated with 20 mg cisplatin (CP)/m2 body surface daily for 5 days as part of a combination therapy for testicular cancer. Simultaneously a vigorous hyperhydration (3000 ml daily) was applied to reduce the nephrotoxic effect induced by the drug, 131I-orthoiodohippurate clearance values obtained by the modified method of Oberhausen did not show any significant evidence of tubular dysfunction after therapy. These results may have been due to the vigorous hydration as well as to the youth of the patients.

5. DOCID:9967 SCORE: 0.000555613968465992
DOCNO: 7093912
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: instrumentation
QUALIFIER: pathology
AUTHOR: L O Tim LO
AUTHOR: G Leiman G
AUTHOR: I Segal I
AUTHOR: D G Hamilton DG
AUTHOR: A Mannell A
PUBTYPE: Journal Article
JOURNALTITLE: Cancer.
COUNTRY: UNITED STATES
TITLE: A suction-abrasive cytology tube for the diagnosis of esophageal carcinoma.
PUBDATE: 19820801
A simple, easily constructed, and inexpensive suction-abrasive cytology tube was developed to study esophageal cytology. The reliability of this method for the diagnosis of esophageal carcinoma was evaluated in 101 patients. Of 47 patients with esophageal carcinoma, 93% were diagnosed correctly on exfoliative cytology. There were no false diagnoses of cancer. The cytology tube was well tolerated by all patients and provided a rapid and reliable method of diagnosis. As a screening procedure, this method may be applicable for widespread use to detect early esophageal cancer in high-risk populations.

6. DOCID:8635 SCORE: 0.000530514761735891
DOCNO: 6391449
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Surgery, Plastic
QUALIFIER: surgery
AUTHOR: B C Mendelson BC
PUBTYPE: Journal Article
JOURNALTITLE: Australian family physician.
COUNTRY: AUSTRALIA
TITLE: Breast reconstruction after mastectomy. What the family physician should know.
PUBDATE: 19840901
The most common female malignancy, cancer of the breast, affects one in 15 women in Australia. A significant number of those who have had a mastectomy seek the advice of their general practitioner about breast reconstruction. The counsel of the past--that they should think themselves fortunate to have survived the mastectomy and 'leave well enough alone'--is no longer valid. This article discusses the need for reconstruction, its worth and the procedures available.

7. DOCID:10772 SCORE: 0.000520079731208383
DOCNO: 6292600
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: injuries
QUALIFIER: etiology
QUALIFIER: adverse effects
QUALIFIER: etiology
AUTHOR: M Strauss M
AUTHOR: M J Bushey MJ
AUTHOR: C Chung C
AUTHOR: S Baum S
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: The Laryngoscope.
COUNTRY: UNITED STATES
TITLE: Fracture of the clavicle following radical neck dissection and postoperative radiotherapy: a case report and review of the literature.
PUBDATE: 19821101
The treatment of head and neck cancer with radiotherapy and radical neck dissection has many recognized complications. Radiotherapy in therapeutic doses can produce devascularization and weakening of bone. Radical neck dissection results in altered mechanics of the shoulder girdle and a disruption of normally balanced forces acting on the clavicle. An unusual case of clavicle fracture which is considered to have resulted from an interaction of the effects of these therapies is discussed. An approach for recognizing and distinguishing this entity by its time course, and radiographic and nuclide bone scan appearance is presented.

8. DOCID:9086 SCORE: 0.000508294714072
DOCNO: 6439202
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Antineoplastic Agents
QUALIFIER: therapeutic use
AUTHOR: S Darkin S
AUTHOR: J McQuillan J
AUTHOR: R K Ralph RK
PUBTYPE: Journal Article
JOURNALTITLE: Biochemical and biophysical research communications.
COUNTRY: UNITED STATES
TITLE: Chlorpromazine: a potential anticancer agent?
PUBDATE: 19841101
The antipsychotic drug chlorpromazine causes scission of the DNA in PY815 mouse mastocytoma cells or isolated PY815 cell nuclei and the broken DNA reseals when chlorpromazine is removed from nuclei. These properties suggest that chlorpromazine interferes with topoisomerase action as do several other DNA-intercalating anti-cancer drugs. However, protein is not associated with the broken DNA after chlorpromazine treatment suggesting a different mode of action on the topoisomerase. Reasons why chlorpromazine may have potential as anti-cancer agent are considered.

9. DOCID:9966 SCORE: 0.000447591608180521
DOCNO: 7201390
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analysis
QUALIFIER: analysis
QUALIFIER: analysis
QUALIFIER: analysis
QUALIFIER: analysis
AUTHOR: T Thorsen T
PUBTYPE: Journal Article
JOURNALTITLE: European journal of cancer & clinical oncology.
COUNTRY: ENGLAND
TITLE: Association of plasminogen activator activity and steroid receptors in human breast cancer.
PUBDATE: 19820201
Plasminogen activating activity (PAA) has been determined in 105 human breast cancer cytosols with a colorimetric assay. PAA has been related to steroid receptors in the same cytosols. A strong positive correlation between PAA and progesterone receptor levels was found (Spearmans coefficient of rank correlation, R - 0.74, P less than 0.001). PAA discriminates between progesterone receptor-positive and -negative tumours, irrespective of oestradiol receptor content. It is suggested that PAA is a marker of functional oestradiol receptor and that fibrinolytic activity may be a causative factor in the low metastatic potential of progesterone receptor-positive tumours.

10. DOCID:11875 SCORE: 0.00024927940206227
DOCNO: 3864319
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: A J Kaelin AJ
AUTHOR: J B Emans JB
PUBTYPE: Journal Article
JOURNALTITLE: Zeitschrift für Kinderchirurgie : organ der Deutschen, der Schweizerischen und der Osterreichischen Gesellschaft für Kinderchirurgie = Surgery in infancy and childhood.
COUNTRY: GERMANY, WEST
TITLE: En-bloc resection for proximal humerus osteogenic sarcoma.
PUBDATE: 19850801
From 1975 to 1982, 101 children were treated for osteogenic sarcoma at the Children's Hospital of the Medical Center and Dana Farber Cancer Institute, Boston. 12 of these patients presented proximal humerus localisation and 8 underwent a local en-bloc resection. In the past these lesions were surgically treated by disarticulation of the shoulder or by interscapulothoracic amputation (forequarter amputation); the death rate was very high. Nowadays, high-dosage chemotherapy and resection of lung metastases carry new hopes for better and prolonged survival, and also for a higher rate of complete remissions. The quality of this prolonged life can be improved if en-bloc resection of the shoulder with upper limb preservation is performed.

11. DOCID:9623 SCORE: 0.000249247883064628
DOCNO: 6702037
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: adverse effects
QUALIFIER: adverse effects
QUALIFIER: surgery
AUTHOR: D E Patterson DE
AUTHOR: H Zincke H
PUBTYPE: Journal Article
JOURNALTITLE: Urology.
COUNTRY: UNITED STATES
TITLE: Perioperative complications of pelvic lymphadenectomy and radical retropubic prostatectomy for Stages C and D1 prostate cancer.
PUBDATE: 19840301
The complications experienced by 205 consecutive patients who underwent bilateral pelvic lymphadenectomy and radical retropubic prostatectomy for surgical Stages C and D1 prostate cancer were analyzed. One hundred five patients had pathologic Stage C disease, and 100 patients had pathologic Stage D1 disease. Seven patients had thromboembolic complications. Wound or pelvic hematomas developed in 6 patients. Only two lymphoceles were detected. Rectal injuries occurred in 6 patients, of whom 4 required colostomies. The overall incidence of perioperative complications was 17 per cent. There was one postoperative death.

12. DOCID:10428 SCORE: 0.000249226407056342
DOCNO: 6575205
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: analogs & derivatives
QUALIFIER: toxicity
QUALIFIER: toxicity
QUALIFIER: chemically induced
QUALIFIER: secondary
AUTHOR: C Hoch-Ligeti C
AUTHOR: P N Harris PN
AUTHOR: H L Stewart HL
PUBTYPE: Journal Article
JOURNALTITLE: Journal of the National Cancer Institute.
COUNTRY: UNITED STATES
TITLE: Endocardial tumors induced by carbamate or fluorenylacetamide derivatives in rats.
PUBDATE: 19830701
Endocardial tumors were induced in 18 rats treated with derivatives of carbamates and in 4 rats treated with derivatives of fluorenylacetamide. The endocardial tumor of 1 rat treated with N,N'-2,7-fluorenylenebisacetamide metastasized to the lung. This is the first report of metastasis of an endocardial tumor. Among the more than 60,000 accessions at the Registry of Experimental Cancers, Division of Cancer Cause and Prevention, National Cancer Institute, there are 4 untreated rats with endocardial tumors. On the basis of the light microscopic morphology, we have classified these endocardial tumors as mesenchymal.

13. DOCID:10011 SCORE: 0.000249225399430531
DOCNO: 6135986
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug effects
QUALIFIER: drug effects
QUALIFIER: toxicity
AUTHOR: J M Mackay JM
AUTHOR: D P Fox DP
AUTHOR: P W Brunt PW
AUTHOR: A W Johnston AW
PUBTYPE: Journal Article
JOURNALTITLE: Mutation research.
COUNTRY: NETHERLANDS
TITLE: Increased sister-chromatid exchange frequency in patients receiving sulphasalazine therapy for ulcerative colitis.
PUBDATE: 19830801
Sister-chromatid exchange and micronucleus frequencies are reported for lymphocytes cultured in vitro from 15 patients receiving sulphasalazine therapy for ulcerative colitis and 15 controls matched for age and sex. While the patients did not differ from matched controls for micronucleus frequency there was a substantial rise in their sister-chromatid exchange frequency. This evidence of DNA damage is discussed in relation to the known cancer risk that ulcerative colitis carries and the possibility of an increased mutation rate in the germ cells of those receiving sulphasalazine therapy.

14. DOCID:10709 SCORE: 0.000249225285824591
DOCNO: 6182514
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Aftercare
QUALIFIER: therapy
AUTHOR: E Sieberth E
PUBTYPE: Journal Article
JOURNALTITLE: Onkologie.
COUNTRY: SWITZERLAND
TITLE: [Clinical, psychological and social aspects of the after care of cancer patients]
PUBDATE: 19820801
The follow-up cancer care has to be based on pathophysiological and psychological principles. Follow-up treatment and rehabilitation must be applied individually. Between these two pillars of follow-up cancer care we find the psychic care and the psychological guidance of the patients--factors of high importance. In all cases of follow-up cancer care, as detailed here, in the last time we find a new group of people approaching us: the self-help groups. In spite of hardly any experience, it seems to be certain that these self-help groups can do a lot in the follow-up cancer care, considering how much there is to do in the vast field of medicine and psychology.