0. DOCID:14684 SCORE: 0.00440792661380785
DOCNO: 2746756
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Chromosome Aberrations
DESCRIPTOR: Chromosomes, Human, Pair 11
DESCRIPTOR: Chromosomes, Human, Pair 9
QUALIFIER: genetics
QUALIFIER: genetics
QUALIFIER: genetics
AUTHOR: R Lundgren R
AUTHOR: P Elfving P
AUTHOR: S Heim S
AUTHOR: U Kristoffersson U
AUTHOR: N Mandahl N
AUTHOR: F Mitelman F
AFFILIATION: Department of Clinical Genetics, University Hospital, Lund, Sweden.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of urology.
COUNTRY: UNITED STATES
TITLE: A squamous cell bladder carcinoma with karyotypic abnormalities reminiscent of transitional cell carcinoma.
PUBDATE: 19890801
A squamous cell carcinoma was investigated cytogenetically by means of chromosome banding. The karyotype was complex with many structural and numerical changes, including -9 and del(11p), aberrations that also have been noted in transitional cell carcinoma. Thus, cytogenetic studies may be an important complement to the histological classification of bladder tumors, and may even contribute to our understanding of the etiology and pathogenesis of the 2 main types of bladder cancer.


1. DOCID:15394 SCORE: 0.00408867425289454
DOCNO: 2694155
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: prevention & control
AUTHOR: W F Malone WF
AUTHOR: G J Kelloff GJ
AUTHOR: C Boone C
AUTHOR: D W Nixon DW
AFFILIATION: Division of Cancer Prevention and Control, National Cancer Institute, Bethesda, Maryland 20852-4200.
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Preventive medicine.
COUNTRY: UNITED STATES
TITLE: Chemoprevention and modern cancer prevention.
PUBDATE: 19890901
Chemoprevention is a new area of research emphasis in cancer control. The rationale is based on the accumulation of laboratory and epidemiological data indicating that various agents may halt or reverse cancer progression in animals and may reduce risks in humans. For planning purposes, research leads are submitted to a strategic system of staging with defined criteria and decision points. A research lead that enters an intervention stage must evolve through a series of phases of testing and evaluation. Human intervention clinical trials have begun to test the hypothesis that certain agents can lower cancer incidence.


2. DOCID:15447 SCORE: 0.00363061015720065
DOCNO: 3568922
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: F P Gall FP
AUTHOR: J Tonak J
AUTHOR: A Altendorf A
PUBTYPE: Journal Article
JOURNALTITLE: Diseases of the colon and rectum.
COUNTRY: UNITED STATES
TITLE: Multivisceral resections in colorectal cancer.
PUBDATE: 19870501
From 1969 to 1983 a total of 1918 patients with colorectal cancer were treated by curative resection. One hundred twenty one patients in this group had multivisceral organ involvement, necessitating extended multivisceral radical resection. Tumor infiltration was proven histologically in 55 percent, while 45 percent had inflammatory adherence to the attached organ only. Postoperative mortality was 12 percent. Dukes' A and B stages were present in 57 percent. The five-year survival rate (postoperative mortality included) was 54 percent for patients with inflammatory adherence, 49 percent for patients with tumor infiltration resected en bloc without tumor tears of rupture, and 17 percent when the surgeon inadvertently had torn or cut into tumor tissue during resection.


3. DOCID:13272 SCORE: 0.0032090238253209
DOCNO: 3061138
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: methods
QUALIFIER: methods
QUALIFIER: surgery
AUTHOR: E G Tseń≠likman EG
PUBTYPE: Journal Article
JOURNALTITLE: Vestnik khirurgii imeni I. I. Grekova.
COUNTRY: USSR
TITLE: [A method of plastic split esophago-gastric anastomosis in proximal resection of the stomach]
PUBDATE: 19880501
An estimation of functional results of gastrectomy for gastric cancer in 183 patients has been made. Radical operations with the formation of Y-shaped interintestinal anastomosis and an artificial food reservoir in the area of the small intestine portion anastomozed with the esophagus were performed in 102 patients. Macroscopic signs of reflux-esophagitis were noted in 2 patients (1.96%), dumping-syndrome in 4 patients (3.9%) and hyperproteinemia in 1 patient (0.98%), i. e. the operations performed gave favourable functional results.


4. DOCID:14922 SCORE: 0.00313037030965903
DOCNO: 2853249
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Hyperthermia, Induced
QUALIFIER: therapy
QUALIFIER: therapy
QUALIFIER: therapy
AUTHOR: G Wiedemann G
AUTHOR: O Mella O
AUTHOR: R S Coltart RS
AUTHOR: B C Schem BC
AUTHOR: O Dahl O
AFFILIATION: Department of Oncology, Haukeland Hospital, University of Bergen, Norway.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Klinische Wochenschrift.
COUNTRY: GERMANY, WEST
TITLE: Hyperthermia improves local tumour control in locally advanced breast cancer.
PUBDATE: 19881001
We report three patients with advanced breast cancer who received hyperthermia (43 degrees C over 1 h, weekly x 4) and radiotherapy as palliative treatment for chest-wall recurrence. The case reports demonstrate situations where hyperthermia may be beneficial. These include tumours where radiotherapy alone is not expected to achieve control, such as large fungating tumours, and in previously irradiated areas. In these patients, hyperthermia with radiation achieves better local control of the tumour and delays the need for systemic chemotherapy. This may improve the quality of palliation.


5. DOCID:15915 SCORE: 0.00299390774290544
DOCNO: 3799577
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: etiology
QUALIFIER: complications
QUALIFIER: etiology
AUTHOR: E Feller E
AUTHOR: F J Schiffman FJ
PUBTYPE: Journal Article
JOURNALTITLE: The American journal of gastroenterology.
COUNTRY: UNITED STATES
TITLE: Colonic obstruction as the first manifestation of ovarian carcinoma.
PUBDATE: 19870101
Fourteen patients with colonic obstruction as the initial manifestation of a malignant ovarian tumor are described. Although common in advanced ovarian tumor, bowel obstruction as the presenting feature of carcinoma of the ovary is not well recognized. Clinical features were that of partial or complete large bowel obstruction, roentgenographically and pathologically involving the sigmoid colon in 12 of 14 patients. Barium enema was abnormal in all 12 patients in whom it was performed. Prognosis may be more favorable in large bowel obstruction as the first clinical manifestation of ovarian cancer than in obstruction occurring in previously diagnosed disease. Our experience suggests that consideration of ovarian pathology is indicated in the presence of signs of large bowel obstruction in women.


6. DOCID:15939 SCORE: 0.00294996976416017
DOCNO: 2591207
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Computer Simulation
DESCRIPTOR: Risk
DESCRIPTOR: Software
AUTHOR: J Wan J
AFFILIATION: University of Alabama, Birmingham 35294.
PUBTYPE: Journal Article
JOURNALTITLE: Computers and biomedical research, an international journal.
COUNTRY: UNITED STATES
TITLE: A method for comparing semi-parametric models with parametric models in competing risks analysis.
PUBDATE: 19891201
In survival analysis, Cox's regression model is often used to assess the effect of covariates on the time of failure. This semi-parametric model has been extended to the situation where more than one cause of failure is of interest. In this paper, two semi-parametric models for the analysis of competing risks with covariates in the presence of independent random censoring are considered. Particular attention is devoted to the comparison between the two models. A method using a measure derived from the generalized variance is proposed. This method is illustrated with an example in a cancer clinical trial. A FORTRAN program for the computer implementation of the method is also discussed.


7. DOCID:13864 SCORE: 0.00277127950526398
DOCNO: 2823605
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: genetics
QUALIFIER: genetics
QUALIFIER: genetics
QUALIFIER: genetics
AUTHOR: H Abusamra H
AUTHOR: S Maximova S
AUTHOR: S Bar-Meir S
AUTHOR: M Krispin M
AUTHOR: H H Rotmensch HH
AFFILIATION: Department of Medicine E, Edith Wolfson Medical Center, Holon, Israel.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: The American journal of medicine.
COUNTRY: UNITED STATES
TITLE: Cancer family syndrome of Lynch.
PUBDATE: 19871101
This report describes a family in whom eight cancers (six colonic and two endometrial) occurred in seven relatives. The colonic cancer was diagnosed in five of the six affected patients at an unusually young age, had a predilection for the proximal colon, and was of the mucinous type in four patients. Polyposis was not found in any colon. The occurrence of cancer in this kindred is characteristic of the "cancer family syndrome" of Lynch.


8. DOCID:15426 SCORE: 0.00277041683117895
DOCNO: 2452890
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pharmacology
QUALIFIER: pharmacology
QUALIFIER: drug effects
AUTHOR: W J Urba WJ
AUTHOR: D L Longo DL
AUTHOR: F A Lombardo FA
AUTHOR: R B Weiss RB
AFFILIATION: Program Resources, Incorporated, NCI-Frederick Cancer Research Facility, MD 21701.
PUBTYPE: Journal Article
JOURNALTITLE: Journal of the National Cancer Institute.
COUNTRY: UNITED STATES
TITLE: Enhancement of natural killer activity in human peripheral blood by flavone acetic acid.
PUBDATE: 19880601
Natural killer cell activity and interferon (IFN) production were measured in 6 patients receiving flavone acetic acid for treatment of cancer. Natural killer cell activity was significantly increased in 3 of 6 patients receiving 6.4 g of flavone acetic acid/m2 by 3-hour iv infusion. Analysis of cell surface markers failed to reveal significant changes in any cell population. There was no evidence of induction of IFN-gamma, but 3 of 4 patients tested had evidence of induction of type I IFN, as measured in a virus neutralization assay.


9. DOCID:14288 SCORE: 0.00260923582653364
DOCNO: 2856316
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: radiotherapy
QUALIFIER: radiotherapy
AUTHOR: A T Turrisi AT
AFFILIATION: Department of Radiation Oncology, Univ. of Pennsylvania Hospital.
PUBTYPE: Journal Article
JOURNALTITLE: Oncology (Williston Park, N.Y.)
COUNTRY: UNITED STATES
TITLE: Limited small cell lung cancer--the role of radiotherapy.
PUBDATE: 19880701
At this time there is no standard therapy for limited small cell lung cancer. Chemotherapy regimens are usually cyclophosphamide-based, but vary in dose, intensity, and in other agents used. Radiotherapy varies in dose, duration, and course (split or continuous). Combinations of the two modalities include sequential therapy, concurrent therapy, and alternating therapy. What emerges from recent trials is the fact that radiotherapy is clearly active in small cell lung cancer and improves local control. What must still be determined are the optimal type of combined chemotherapy/radiotherapy and the best method of integration and timing.


10. DOCID:14131 SCORE: 0.00249392870160845
DOCNO: 2688015
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: standards
QUALIFIER: pathology
AUTHOR: D Brohee D
AUTHOR: A Van Meerhaeghe A
AUTHOR: N Dourov N
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Revue médicale de Bruxelles.
COUNTRY: BELGIUM
TITLE: [The gold standard and optimalization of diagnostic choice: the pulmonary nodule and transthoracic pulmonary puncture-biopsy]
PUBDATE: 19891101
In this review of the literature, it is emphasized that the published results about the transthoracic pulmonary needle biopsy (TPNB) cannot be readily evaluated due to the inconsistency of the reference tests, the methods and the investigated subjects. Gold-standards for evaluation of lung tumors have been described and are recalled. The limits of the TPNB are pointed out in the diagnosis of solitary pulmonary nodules and benign lesions. In a bayesian approach, it is shown that the TPNB is only useful in confirming an a-priori diagnosis of cancer.


11. DOCID:14433 SCORE: 0.00243259608593353
DOCNO: 2545893
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: G Barnes G
AUTHOR: W E Matory WE
PUBTYPE: Journal Article
JOURNALTITLE: Journal of the National Medical Association.
COUNTRY: UNITED STATES
TITLE: Needle localization and surgical management of occult breast lesions.
PUBDATE: 19890601
Screening mammography can locate small breast cancer lesions not detectable on physical examination. In this study, the records of 57 patients undergoing radiographically guided preoperative needle localization were reviewed for the period August 1986 to May 1988. Of the 57 cases, 15.8% were positive for cancer and 84.2% were benign breast lesions. Invasive ductal carcinoma was the pathologic diagnosis in all malignant biopsies, except for one case of carcinoma in situ. All positive lesions had shown as microcalcifications on mammogram. The authors examine the criteria for biopsy and discuss their experience with needle localization of occult breast lesion suspicious of breast cancer.


12. DOCID:13240 SCORE: 0.00242543376598272
DOCNO: 3299423
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: psychology
AUTHOR: H T Kriesel HT
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Primary care.
COUNTRY: UNITED STATES
TITLE: The psychosocial aspects of malignancy.
PUBDATE: 19870601
This article has described many of the psychosocial issues associated with malignancy. Issues related to delivering the diagnosis of cancer, such as telling the truth, including the family, and initiating a "shared meaning" process, were considered. Patient reactions related to cancer such as grief, depression, and needs for control were described. Family reactions to the cancer patient, including anticipatory grief and weariness, were noted. The need for psychosocial support for the family of the cancer patient was discussed. Finally, the need for caregivers to pay attention to their own emotional needs was described.


13. DOCID:13270 SCORE: 0.00237745066124806
DOCNO: 2725915
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
AUTHOR: E Bortolani E
AUTHOR: M Erba M
AUTHOR: P Pizzocari P
PUBTYPE: Journal Article
JOURNALTITLE: Minerva chirurgica.
COUNTRY: ITALY
TITLE: [Prognostic evaluation of malignant tumors of the lower third of the rectum]
PUBDATE: 19890301
Authors took into consideration 44 cases of neoplasm located in the lower third of the rectum. This site represents one of the most affected by the large bowel cancer and is also distressed by the highest frequency of late recurrences after curative resection. A careful follow-up of these patients has been made in order to define the survival rate in relation to different prognostic factors. To this purpose staging, grading and other morphologic features of the neoplasm turned out to be especially significant.


14. DOCID:14482 SCORE: 0.00234535576144012
DOCNO: 2471861
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Breast Neoplasms
QUALIFIER: secondary
QUALIFIER: secondary
QUALIFIER: surgery
AUTHOR: Y Shimada Y
AUTHOR: M Imamura M
AUTHOR: T Tobe T
AFFILIATION: First Department of Surgery, Faculty of Medicine Kyoto University, Japan.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: The Japanese journal of surgery.
COUNTRY: JAPAN
TITLE: Successful esophagectomy for metastatic carcinoma of the esophagus from breast cancer--a case report.
PUBDATE: 19890101
A case of progressive dysphagia due to metastatic carcinoma of the esophagus from breast cancer is described herein. The patient was a 55-year-old Japanese woman who had undergone a right radical mastectomy for carcinoma of the right breast 9 years previously. We performed a subtotal esophagectomy and reconstruction, using the stomach. She is now well and working without any further symptoms, five years after surgery. Thus, palliative surgery for the complications caused by metastatic carcinoma of the esophagus may be worthwhile.