0. DOCID:9722 SCORE: 0.00446824675563077
DOCNO: 6709743
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: psychology
AUTHOR: L A Stevens LA
AUTHOR: M H McGrath MH
AUTHOR: R G Druss RG
AUTHOR: S J Kister SJ
AUTHOR: F E Gump FE
AUTHOR: K A Forde KA
PUBTYPE: Journal Article
JOURNALTITLE: Plastic and reconstructive surgery.
COUNTRY: UNITED STATES
TITLE: The psychological impact of immediate breast reconstruction for women with early breast cancer.
PUBDATE: 19840401
Twenty-five patients were evaluated, 13 who had immediate breast reconstruction and 12 who had delayed breast reconstruction for early breast cancer. Data were elicited about the psychological impact of the cancer, the mastectomy, and the reconstruction. Our results support the conclusion that immediate breast reconstruction is accompanied by a lower incidence of psychological morbidity postoperatively, and we recommend that immediate breast reconstruction be offered as an alternative to women with early breast cancer.


1. DOCID:14684 SCORE: 0.00440792661380785
DOCNO: 2746756
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Chromosome Aberrations
DESCRIPTOR: Chromosomes, Human, Pair 11
DESCRIPTOR: Chromosomes, Human, Pair 9
QUALIFIER: genetics
QUALIFIER: genetics
QUALIFIER: genetics
AUTHOR: R Lundgren R
AUTHOR: P Elfving P
AUTHOR: S Heim S
AUTHOR: U Kristoffersson U
AUTHOR: N Mandahl N
AUTHOR: F Mitelman F
AFFILIATION: Department of Clinical Genetics, University Hospital, Lund, Sweden.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of urology.
COUNTRY: UNITED STATES
TITLE: A squamous cell bladder carcinoma with karyotypic abnormalities reminiscent of transitional cell carcinoma.
PUBDATE: 19890801
A squamous cell carcinoma was investigated cytogenetically by means of chromosome banding. The karyotype was complex with many structural and numerical changes, including -9 and del(11p), aberrations that also have been noted in transitional cell carcinoma. Thus, cytogenetic studies may be an important complement to the histological classification of bladder tumors, and may even contribute to our understanding of the etiology and pathogenesis of the 2 main types of bladder cancer.


2. DOCID:11785 SCORE: 0.00421369741099242
DOCNO: 6340203
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: diagnosis
AUTHOR: H MacMahon H
AUTHOR: J V Courtney JV
AUTHOR: A G Little AG
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Seminars in oncology.
COUNTRY: UNITED STATES
TITLE: Diagnostic methods in lung cancer.
PUBDATE: 19830301
We feel that the guidelines described here reflect the state of the art at the time of writing (April 1982). The role of CT scanning is likely to evolve further and nuclear magnetic resonance (NMR) will probably play a significant role in the future. Experience, expertise, and equipment will vary from one hospital to another and thus rigid rules cannot reasonably be applied for the workup of suspected lung cancer. Ideally the diagnostic approach to an individual patient will be highly tailored, not only in regard to the nature of the pulmonary lesion, but also to his or her overall medical and social situation. We have found that a policy of early consultation between clinician and imaging specialist most readily facilitates effective use of available diagnostic resources.


3. DOCID:15394 SCORE: 0.00408867425289454
DOCNO: 2694155
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: prevention & control
AUTHOR: W F Malone WF
AUTHOR: G J Kelloff GJ
AUTHOR: C Boone C
AUTHOR: D W Nixon DW
AFFILIATION: Division of Cancer Prevention and Control, National Cancer Institute, Bethesda, Maryland 20852-4200.
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
PUBTYPE: Review
JOURNALTITLE: Preventive medicine.
COUNTRY: UNITED STATES
TITLE: Chemoprevention and modern cancer prevention.
PUBDATE: 19890901
Chemoprevention is a new area of research emphasis in cancer control. The rationale is based on the accumulation of laboratory and epidemiological data indicating that various agents may halt or reverse cancer progression in animals and may reduce risks in humans. For planning purposes, research leads are submitted to a strategic system of staging with defined criteria and decision points. A research lead that enters an intervention stage must evolve through a series of phases of testing and evaluation. Human intervention clinical trials have begun to test the hypothesis that certain agents can lower cancer incidence.


4. DOCID:11705 SCORE: 0.00402282201692395
DOCNO: 6407408
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: therapeutic use
QUALIFIER: drug therapy
AUTHOR: F Alcobendas F
AUTHOR: A Milla A
AUTHOR: J Estape J
AUTHOR: J Curto J
AUTHOR: C Pera C
PUBTYPE: Clinical Trial
PUBTYPE: Journal Article
PUBTYPE: Randomized Controlled Trial
JOURNALTITLE: Annals of surgery.
COUNTRY: UNITED STATES
TITLE: Mitomycin C as an adjuvant in resected gastric cancer.
PUBDATE: 19830701
As a result of their previous experience with mitomycin C at high discontinuous doses in advanced gastric cancer, the authors studied its role as an adjuvant for locally advanced cases after surgical complete resection. Results from 70 evaluable patients are presented. Patients were allocated randomly to receive mitomycin C, 20 mg/m2 I.V. direct once every 6 weeks, four courses, or a placebo. After a follow-up period of 250 weeks, seven patients of treatment arm and 23 controls have already relapsed (p less than 0.001). Toxicity was moderate and controllable by symptomatic measures. The authors consider this investigation a positive contribution in the field of adjuvant therapy of gastric cancer.


5. DOCID:11631 SCORE: 0.00402278791245427
DOCNO: 6887659
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: pathology
AUTHOR: A Suzuki A
AUTHOR: T Takahashi T
PUBTYPE: Journal Article
JOURNALTITLE: The Japanese journal of surgery.
COUNTRY: JAPAN
TITLE: Histogenesis of the gallbladder carcinoma induced by methylcholanthrene beeswax pellets in hamsters.
PUBDATE: 19830101
Gallbladder carcinoma was induced in hamsters by inserting methylcholanthrene beeswax pellets into the gallbladder lumen. The histogenesis and mode of development of the cancer was studied. The mode of development was classified into four; the infiltrative, the polypoid, the para-adenoma, and the mixed type. Twenty-one gallbladder carcinoma included six of the infiltrative type, seven of the polypoid type, three of the para-adenoma type (each case was accompanied by the infiltrative type), and eight of the mixed type (containing three of the infiltrative plus the para-adenoma type, and five of the infiltrative plus the polypoid type). Concerning histogenesis, the infiltrative type developed as de novo cancer. The polypoid and the para-adenoma type developed from adenomatous hyperplasia or adenoma.


6. DOCID:15447 SCORE: 0.00363061015720065
DOCNO: 3568922
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: F P Gall FP
AUTHOR: J Tonak J
AUTHOR: A Altendorf A
PUBTYPE: Journal Article
JOURNALTITLE: Diseases of the colon and rectum.
COUNTRY: UNITED STATES
TITLE: Multivisceral resections in colorectal cancer.
PUBDATE: 19870501
From 1969 to 1983 a total of 1918 patients with colorectal cancer were treated by curative resection. One hundred twenty one patients in this group had multivisceral organ involvement, necessitating extended multivisceral radical resection. Tumor infiltration was proven histologically in 55 percent, while 45 percent had inflammatory adherence to the attached organ only. Postoperative mortality was 12 percent. Dukes' A and B stages were present in 57 percent. The five-year survival rate (postoperative mortality included) was 54 percent for patients with inflammatory adherence, 49 percent for patients with tumor infiltration resected en bloc without tumor tears of rupture, and 17 percent when the surgeon inadvertently had torn or cut into tumor tissue during resection.


7. DOCID:11233 SCORE: 0.00337782726058435
DOCNO: 6834499
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: pathology
QUALIFIER: diagnosis
AUTHOR: W J Catalona WJ
AUTHOR: J Fleischmann J
AUTHOR: M Menon M
PUBTYPE: Journal Article
JOURNALTITLE: The Journal of urology.
COUNTRY: UNITED STATES
TITLE: Pelvic lymph node status as predictor of extracapsular tumor extension in clinical stage B prostatic cancer.
PUBDATE: 19830201
To examine the accuracy of normal pelvic lymph node status in identifying patients with clinical stage B prostatic cancer not having extracapsular tumor extension we reviewed 63 consecutive patients (39 stage B1 and 24 stage B2) treated with radical prostatectomy. Ten per cent of the patients with stage B1 lesions (tumor involving 1 lobe) and 38 per cent with stage B2 lesions (tumor involving both lobes) had extracapsular extension. Extracapsular tumor extension was more common in patients with larger, less differentiated lesions. The results suggest that a negative pelvic lymphadenectomy does not exclude with a high degree of confidence extracapsular tumor extension in patients with clinical stage B2 prostatic cancer.


8. DOCID:13272 SCORE: 0.0032090238253209
DOCNO: 3061138
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: methods
QUALIFIER: methods
QUALIFIER: surgery
AUTHOR: E G Tseń≠likman EG
PUBTYPE: Journal Article
JOURNALTITLE: Vestnik khirurgii imeni I. I. Grekova.
COUNTRY: USSR
TITLE: [A method of plastic split esophago-gastric anastomosis in proximal resection of the stomach]
PUBDATE: 19880501
An estimation of functional results of gastrectomy for gastric cancer in 183 patients has been made. Radical operations with the formation of Y-shaped interintestinal anastomosis and an artificial food reservoir in the area of the small intestine portion anastomozed with the esophagus were performed in 102 patients. Macroscopic signs of reflux-esophagitis were noted in 2 patients (1.96%), dumping-syndrome in 4 patients (3.9%) and hyperproteinemia in 1 patient (0.98%), i. e. the operations performed gave favourable functional results.


9. DOCID:11647 SCORE: 0.00316523872142919
DOCNO: 7078184
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: immunology
QUALIFIER: analysis
QUALIFIER: immunology
AUTHOR: N N Khanna NN
AUTHOR: S N Das SN
AUTHOR: S Khanna S
PUBTYPE: Journal Article
JOURNALTITLE: Journal of surgical oncology.
COUNTRY: UNITED STATES
TITLE: Serum immunoglobulins in squamous cell carcinoma of the oral cavity.
PUBDATE: 19820501
Serum immunoglobulins (IgG, IgA, and IgM) have been studied in 70 patients with squamous cell carcinoma of oral cavity and in 40 age-matched normal controls. The results were correlated with clinical stage, tumor size, lymph node status, tumor differentiation, and treatment modalities. There was a significant rise in serum IgM and IgA in oral cancer patients as compared to controls. It was further raised in advanced clinical stage, but tumor size and histological differentiation and treatment modalities (surgery and chemotherapy) do not seem to affect serum immunoglobulin levels. The observations implies that the extension and dissemination of tumor mass is the important factor for the change in serum immunoglobulin level in squamous cell carcinoma of the oral cavity.


10. DOCID:14922 SCORE: 0.00313037030965903
DOCNO: 2853249
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Hyperthermia, Induced
QUALIFIER: therapy
QUALIFIER: therapy
QUALIFIER: therapy
AUTHOR: G Wiedemann G
AUTHOR: O Mella O
AUTHOR: R S Coltart RS
AUTHOR: B C Schem BC
AUTHOR: O Dahl O
AFFILIATION: Department of Oncology, Haukeland Hospital, University of Bergen, Norway.
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Klinische Wochenschrift.
COUNTRY: GERMANY, WEST
TITLE: Hyperthermia improves local tumour control in locally advanced breast cancer.
PUBDATE: 19881001
We report three patients with advanced breast cancer who received hyperthermia (43 degrees C over 1 h, weekly x 4) and radiotherapy as palliative treatment for chest-wall recurrence. The case reports demonstrate situations where hyperthermia may be beneficial. These include tumours where radiotherapy alone is not expected to achieve control, such as large fungating tumours, and in previously irradiated areas. In these patients, hyperthermia with radiation achieves better local control of the tumour and delays the need for systemic chemotherapy. This may improve the quality of palliation.


11. DOCID:11521 SCORE: 0.00310345439286452
DOCNO: 4053924
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: surgery
QUALIFIER: surgery
AUTHOR: J P Bader JP
PUBTYPE: Journal Article
JOURNALTITLE: Digestive diseases and sciences.
COUNTRY: UNITED STATES
TITLE: The surgical treatment of peptic ulcer disease. A physician's view.
PUBDATE: 19851101
Current opinions concerning the surgical treatment of peptic ulcer disease are reviewed. Because of the differences between duodenal and gastric ulcers the approaches to the surgical treatments of these lesions differ. For duodenal ulcers surgery is seldom required when the ulcer craters do not heal or, more often, when the disease is not adequately controlled. In these cases the preferred treatment is hyperselective vagotomy. However, the relatively high level of recurrence some years after hyperselective vagotomy may lead to more radical surgery in the future. In contrast to duodenal ulcers, the risk of cancer with gastric ulcers, although low and difficult to evaluate, often leads to quicker surgical intervention. For gastric ulcers the surgeon faces the difficult choice between partial gastrectomy and vagotomy with ulcer excision.


12. DOCID:8905 SCORE: 0.00307601941308151
DOCNO: 2578557
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: drug therapy
QUALIFIER: adverse effects
QUALIFIER: drug therapy
AUTHOR: B J Brooks BJ
AUTHOR: M E Lippman ME
PUBTYPE: Case Reports
PUBTYPE: Journal Article
JOURNALTITLE: Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
COUNTRY: UNITED STATES
TITLE: Tamoxifen flare in advanced endometrial carcinoma.
PUBDATE: 19850201
Tamoxifen citrate has recently been shown to be effective palliative therapy in advanced endometrial carcinoma. Flare reactions from tamoxifen are well known in treatment of metastatic breast carcinoma and are not an indication for stopping therapy. We report a patient being treated with tamoxifen for advanced endometrial cancer who developed acute abdominal pain as a manifestation of a flare reaction and the significance of this observation.


13. DOCID:15915 SCORE: 0.00299390774290544
DOCNO: 3799577
OWNER: NLM
STATUS: MEDLINE
QUALIFIER: complications
QUALIFIER: etiology
QUALIFIER: complications
QUALIFIER: etiology
AUTHOR: E Feller E
AUTHOR: F J Schiffman FJ
PUBTYPE: Journal Article
JOURNALTITLE: The American journal of gastroenterology.
COUNTRY: UNITED STATES
TITLE: Colonic obstruction as the first manifestation of ovarian carcinoma.
PUBDATE: 19870101
Fourteen patients with colonic obstruction as the initial manifestation of a malignant ovarian tumor are described. Although common in advanced ovarian tumor, bowel obstruction as the presenting feature of carcinoma of the ovary is not well recognized. Clinical features were that of partial or complete large bowel obstruction, roentgenographically and pathologically involving the sigmoid colon in 12 of 14 patients. Barium enema was abnormal in all 12 patients in whom it was performed. Prognosis may be more favorable in large bowel obstruction as the first clinical manifestation of ovarian cancer than in obstruction occurring in previously diagnosed disease. Our experience suggests that consideration of ovarian pathology is indicated in the presence of signs of large bowel obstruction in women.


14. DOCID:15939 SCORE: 0.00294996976416017
DOCNO: 2591207
OWNER: NLM
STATUS: MEDLINE
DESCRIPTOR: Computer Simulation
DESCRIPTOR: Risk
DESCRIPTOR: Software
AUTHOR: J Wan J
AFFILIATION: University of Alabama, Birmingham 35294.
PUBTYPE: Journal Article
JOURNALTITLE: Computers and biomedical research, an international journal.
COUNTRY: UNITED STATES
TITLE: A method for comparing semi-parametric models with parametric models in competing risks analysis.
PUBDATE: 19891201
In survival analysis, Cox's regression model is often used to assess the effect of covariates on the time of failure. This semi-parametric model has been extended to the situation where more than one cause of failure is of interest. In this paper, two semi-parametric models for the analysis of competing risks with covariates in the presence of independent random censoring are considered. Particular attention is devoted to the comparison between the two models. A method using a measure derived from the generalized variance is proposed. This method is illustrated with an example in a cancer clinical trial. A FORTRAN program for the computer implementation of the method is also discussed.